KEGG   Mastomys coucha (southern multimammate mouse): 116073648
Entry
116073648         CDS       T07224                                 
Symbol
Mapk6
Name
(RefSeq) mitogen-activated protein kinase 6
  KO
K04371  mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
Organism
mcoc  Mastomys coucha (southern multimammate mouse)
Pathway
mcoc01521  EGFR tyrosine kinase inhibitor resistance
mcoc01522  Endocrine resistance
mcoc01524  Platinum drug resistance
mcoc04010  MAPK signaling pathway
mcoc04012  ErbB signaling pathway
mcoc04014  Ras signaling pathway
mcoc04015  Rap1 signaling pathway
mcoc04022  cGMP-PKG signaling pathway
mcoc04024  cAMP signaling pathway
mcoc04062  Chemokine signaling pathway
mcoc04066  HIF-1 signaling pathway
mcoc04068  FoxO signaling pathway
mcoc04071  Sphingolipid signaling pathway
mcoc04072  Phospholipase D signaling pathway
mcoc04114  Oocyte meiosis
mcoc04140  Autophagy - animal
mcoc04148  Efferocytosis
mcoc04150  mTOR signaling pathway
mcoc04151  PI3K-Akt signaling pathway
mcoc04210  Apoptosis
mcoc04218  Cellular senescence
mcoc04261  Adrenergic signaling in cardiomyocytes
mcoc04270  Vascular smooth muscle contraction
mcoc04350  TGF-beta signaling pathway
mcoc04360  Axon guidance
mcoc04370  VEGF signaling pathway
mcoc04371  Apelin signaling pathway
mcoc04380  Osteoclast differentiation
mcoc04510  Focal adhesion
mcoc04517  IgSF CAM signaling
mcoc04520  Adherens junction
mcoc04540  Gap junction
mcoc04550  Signaling pathways regulating pluripotency of stem cells
mcoc04611  Platelet activation
mcoc04613  Neutrophil extracellular trap formation
mcoc04620  Toll-like receptor signaling pathway
mcoc04621  NOD-like receptor signaling pathway
mcoc04625  C-type lectin receptor signaling pathway
mcoc04650  Natural killer cell mediated cytotoxicity
mcoc04657  IL-17 signaling pathway
mcoc04658  Th1 and Th2 cell differentiation
mcoc04659  Th17 cell differentiation
mcoc04660  T cell receptor signaling pathway
mcoc04662  B cell receptor signaling pathway
mcoc04664  Fc epsilon RI signaling pathway
mcoc04666  Fc gamma R-mediated phagocytosis
mcoc04668  TNF signaling pathway
mcoc04713  Circadian entrainment
mcoc04720  Long-term potentiation
mcoc04722  Neurotrophin signaling pathway
mcoc04723  Retrograde endocannabinoid signaling
mcoc04724  Glutamatergic synapse
mcoc04725  Cholinergic synapse
mcoc04726  Serotonergic synapse
mcoc04730  Long-term depression
mcoc04810  Regulation of actin cytoskeleton
mcoc04910  Insulin signaling pathway
mcoc04912  GnRH signaling pathway
mcoc04914  Progesterone-mediated oocyte maturation
mcoc04915  Estrogen signaling pathway
mcoc04916  Melanogenesis
mcoc04917  Prolactin signaling pathway
mcoc04919  Thyroid hormone signaling pathway
mcoc04921  Oxytocin signaling pathway
mcoc04926  Relaxin signaling pathway
mcoc04928  Parathyroid hormone synthesis, secretion and action
mcoc04929  GnRH secretion
mcoc04930  Type II diabetes mellitus
mcoc04933  AGE-RAGE signaling pathway in diabetic complications
mcoc04934  Cushing syndrome
mcoc04935  Growth hormone synthesis, secretion and action
mcoc04960  Aldosterone-regulated sodium reabsorption
mcoc05010  Alzheimer disease
mcoc05020  Prion disease
mcoc05022  Pathways of neurodegeneration - multiple diseases
mcoc05034  Alcoholism
mcoc05132  Salmonella infection
mcoc05133  Pertussis
mcoc05135  Yersinia infection
mcoc05140  Leishmaniasis
mcoc05142  Chagas disease
mcoc05145  Toxoplasmosis
mcoc05152  Tuberculosis
mcoc05160  Hepatitis C
mcoc05161  Hepatitis B
mcoc05163  Human cytomegalovirus infection
mcoc05164  Influenza A
mcoc05165  Human papillomavirus infection
mcoc05166  Human T-cell leukemia virus 1 infection
mcoc05167  Kaposi sarcoma-associated herpesvirus infection
mcoc05170  Human immunodeficiency virus 1 infection
mcoc05171  Coronavirus disease - COVID-19
mcoc05200  Pathways in cancer
mcoc05203  Viral carcinogenesis
mcoc05205  Proteoglycans in cancer
mcoc05206  MicroRNAs in cancer
mcoc05207  Chemical carcinogenesis - receptor activation
mcoc05208  Chemical carcinogenesis - reactive oxygen species
mcoc05210  Colorectal cancer
mcoc05211  Renal cell carcinoma
mcoc05212  Pancreatic cancer
mcoc05213  Endometrial cancer
mcoc05214  Glioma
mcoc05215  Prostate cancer
mcoc05216  Thyroid cancer
mcoc05218  Melanoma
mcoc05219  Bladder cancer
mcoc05220  Chronic myeloid leukemia
mcoc05221  Acute myeloid leukemia
mcoc05223  Non-small cell lung cancer
mcoc05224  Breast cancer
mcoc05225  Hepatocellular carcinoma
mcoc05226  Gastric cancer
mcoc05230  Central carbon metabolism in cancer
mcoc05231  Choline metabolism in cancer
mcoc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mcoc05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mcoc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    116073648 (Mapk6)
   04012 ErbB signaling pathway
    116073648 (Mapk6)
   04014 Ras signaling pathway
    116073648 (Mapk6)
   04015 Rap1 signaling pathway
    116073648 (Mapk6)
   04350 TGF-beta signaling pathway
    116073648 (Mapk6)
   04370 VEGF signaling pathway
    116073648 (Mapk6)
   04371 Apelin signaling pathway
    116073648 (Mapk6)
   04668 TNF signaling pathway
    116073648 (Mapk6)
   04066 HIF-1 signaling pathway
    116073648 (Mapk6)
   04068 FoxO signaling pathway
    116073648 (Mapk6)
   04072 Phospholipase D signaling pathway
    116073648 (Mapk6)
   04071 Sphingolipid signaling pathway
    116073648 (Mapk6)
   04024 cAMP signaling pathway
    116073648 (Mapk6)
   04022 cGMP-PKG signaling pathway
    116073648 (Mapk6)
   04151 PI3K-Akt signaling pathway
    116073648 (Mapk6)
   04150 mTOR signaling pathway
    116073648 (Mapk6)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    116073648 (Mapk6)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    116073648 (Mapk6)
   04148 Efferocytosis
    116073648 (Mapk6)
  09143 Cell growth and death
   04114 Oocyte meiosis
    116073648 (Mapk6)
   04210 Apoptosis
    116073648 (Mapk6)
   04218 Cellular senescence
    116073648 (Mapk6)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    116073648 (Mapk6)
   04520 Adherens junction
    116073648 (Mapk6)
   04540 Gap junction
    116073648 (Mapk6)
   04550 Signaling pathways regulating pluripotency of stem cells
    116073648 (Mapk6)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    116073648 (Mapk6)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    116073648 (Mapk6)
   04613 Neutrophil extracellular trap formation
    116073648 (Mapk6)
   04620 Toll-like receptor signaling pathway
    116073648 (Mapk6)
   04621 NOD-like receptor signaling pathway
    116073648 (Mapk6)
   04625 C-type lectin receptor signaling pathway
    116073648 (Mapk6)
   04650 Natural killer cell mediated cytotoxicity
    116073648 (Mapk6)
   04660 T cell receptor signaling pathway
    116073648 (Mapk6)
   04658 Th1 and Th2 cell differentiation
    116073648 (Mapk6)
   04659 Th17 cell differentiation
    116073648 (Mapk6)
   04657 IL-17 signaling pathway
    116073648 (Mapk6)
   04662 B cell receptor signaling pathway
    116073648 (Mapk6)
   04664 Fc epsilon RI signaling pathway
    116073648 (Mapk6)
   04666 Fc gamma R-mediated phagocytosis
    116073648 (Mapk6)
   04062 Chemokine signaling pathway
    116073648 (Mapk6)
  09152 Endocrine system
   04910 Insulin signaling pathway
    116073648 (Mapk6)
   04929 GnRH secretion
    116073648 (Mapk6)
   04912 GnRH signaling pathway
    116073648 (Mapk6)
   04915 Estrogen signaling pathway
    116073648 (Mapk6)
   04914 Progesterone-mediated oocyte maturation
    116073648 (Mapk6)
   04917 Prolactin signaling pathway
    116073648 (Mapk6)
   04921 Oxytocin signaling pathway
    116073648 (Mapk6)
   04926 Relaxin signaling pathway
    116073648 (Mapk6)
   04935 Growth hormone synthesis, secretion and action
    116073648 (Mapk6)
   04919 Thyroid hormone signaling pathway
    116073648 (Mapk6)
   04928 Parathyroid hormone synthesis, secretion and action
    116073648 (Mapk6)
   04916 Melanogenesis
    116073648 (Mapk6)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    116073648 (Mapk6)
   04270 Vascular smooth muscle contraction
    116073648 (Mapk6)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    116073648 (Mapk6)
  09156 Nervous system
   04724 Glutamatergic synapse
    116073648 (Mapk6)
   04725 Cholinergic synapse
    116073648 (Mapk6)
   04726 Serotonergic synapse
    116073648 (Mapk6)
   04720 Long-term potentiation
    116073648 (Mapk6)
   04730 Long-term depression
    116073648 (Mapk6)
   04723 Retrograde endocannabinoid signaling
    116073648 (Mapk6)
   04722 Neurotrophin signaling pathway
    116073648 (Mapk6)
  09158 Development and regeneration
   04360 Axon guidance
    116073648 (Mapk6)
   04380 Osteoclast differentiation
    116073648 (Mapk6)
  09159 Environmental adaptation
   04713 Circadian entrainment
    116073648 (Mapk6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    116073648 (Mapk6)
   05206 MicroRNAs in cancer
    116073648 (Mapk6)
   05205 Proteoglycans in cancer
    116073648 (Mapk6)
   05207 Chemical carcinogenesis - receptor activation
    116073648 (Mapk6)
   05208 Chemical carcinogenesis - reactive oxygen species
    116073648 (Mapk6)
   05203 Viral carcinogenesis
    116073648 (Mapk6)
   05230 Central carbon metabolism in cancer
    116073648 (Mapk6)
   05231 Choline metabolism in cancer
    116073648 (Mapk6)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    116073648 (Mapk6)
  09162 Cancer: specific types
   05210 Colorectal cancer
    116073648 (Mapk6)
   05212 Pancreatic cancer
    116073648 (Mapk6)
   05225 Hepatocellular carcinoma
    116073648 (Mapk6)
   05226 Gastric cancer
    116073648 (Mapk6)
   05214 Glioma
    116073648 (Mapk6)
   05216 Thyroid cancer
    116073648 (Mapk6)
   05221 Acute myeloid leukemia
    116073648 (Mapk6)
   05220 Chronic myeloid leukemia
    116073648 (Mapk6)
   05218 Melanoma
    116073648 (Mapk6)
   05211 Renal cell carcinoma
    116073648 (Mapk6)
   05219 Bladder cancer
    116073648 (Mapk6)
   05215 Prostate cancer
    116073648 (Mapk6)
   05213 Endometrial cancer
    116073648 (Mapk6)
   05224 Breast cancer
    116073648 (Mapk6)
   05223 Non-small cell lung cancer
    116073648 (Mapk6)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    116073648 (Mapk6)
   05170 Human immunodeficiency virus 1 infection
    116073648 (Mapk6)
   05161 Hepatitis B
    116073648 (Mapk6)
   05160 Hepatitis C
    116073648 (Mapk6)
   05171 Coronavirus disease - COVID-19
    116073648 (Mapk6)
   05164 Influenza A
    116073648 (Mapk6)
   05163 Human cytomegalovirus infection
    116073648 (Mapk6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    116073648 (Mapk6)
   05165 Human papillomavirus infection
    116073648 (Mapk6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    116073648 (Mapk6)
   05135 Yersinia infection
    116073648 (Mapk6)
   05133 Pertussis
    116073648 (Mapk6)
   05152 Tuberculosis
    116073648 (Mapk6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    116073648 (Mapk6)
   05140 Leishmaniasis
    116073648 (Mapk6)
   05142 Chagas disease
    116073648 (Mapk6)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    116073648 (Mapk6)
   05020 Prion disease
    116073648 (Mapk6)
   05022 Pathways of neurodegeneration - multiple diseases
    116073648 (Mapk6)
  09165 Substance dependence
   05034 Alcoholism
    116073648 (Mapk6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    116073648 (Mapk6)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    116073648 (Mapk6)
   04933 AGE-RAGE signaling pathway in diabetic complications
    116073648 (Mapk6)
   04934 Cushing syndrome
    116073648 (Mapk6)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    116073648 (Mapk6)
   01524 Platinum drug resistance
    116073648 (Mapk6)
   01522 Endocrine resistance
    116073648 (Mapk6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mcoc01001]
    116073648 (Mapk6)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mcoc03036]
    116073648 (Mapk6)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mcoc04147]
    116073648 (Mapk6)
Enzymes [BR:mcoc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     116073648 (Mapk6)
Protein kinases [BR:mcoc01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   116073648 (Mapk6)
Chromosome and associated proteins [BR:mcoc03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     116073648 (Mapk6)
Exosome [BR:mcoc04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   116073648 (Mapk6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr
Other DBs
NCBI-GeneID: 116073648
NCBI-ProteinID: XP_031201568
LinkDB
Position
Unknown
AA seq 311 aa
MDGSFDCDCDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAID
MWAAGCIFAEMLTGKALFAGAHELEQMQLILESIPVVHEEDRQELLSVIPVYIRNDMTEP
HKPLTQLLPGISREALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPTDEPISSHPFHI
EDEVDDILLMDETHSHIYNWERYHDCQFSEHDWPIHNNFDIDEVQLDPRALSDVTDEEEV
QVDPRKYLDGDREKYLEDPAFDTSYSAEPCWQYPDHHENKYCDLECSHTCNYKTRSSSYL
DNLVWRESEVN
NT seq 933 nt   +upstreamnt  +downstreamnt
atggacggtagctttgactgtgattgtgacttggtgctgaagataggtgactttggcctg
gcacggatcatggatcctcattattcccataagggtcatctttctgaaggattggttacc
aaatggtacagatctccacggcttttactttctcctaataattacactaaagccattgac
atgtgggctgcaggctgcatctttgctgaaatgctgactggtaaagccctctttgcaggt
gcacatgaacttgaacagatgcagctgatcttagagtctatccctgttgtgcatgaggaa
gatcggcaggagcttctcagcgtgattccagtttacattagaaacgacatgactgagcca
cacaaaccgctaactcagctgcttccggggattagtcgtgaagcactggatttcctggaa
cagattctgaccttcagccccatggaccggctgacagccgaggaagcactttcccatccc
tacatgagcatctactccttcccaacagatgaaccgatttcaagccatcctttccacata
gaagatgaagtggacgacattttgcttatggatgaaacacatagtcacatttataactgg
gaaaggtaccacgactgtcagttctcagaacatgactggcctattcataacaactttgat
attgatgaggttcagcttgaccccagagctctgtctgatgtcactgatgaagaagaagtt
caagttgatcctcgaaagtacttggacggagaccgagagaagtatctggaagatcccgcc
ttcgacaccagctactctgctgagccttgctggcagtacccagatcaccacgagaacaag
tactgtgatctggagtgtagccacacttgtaactacaaaacaaggtcatcatcataccta
gataacctggtgtggagggagagcgaggttaac

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