Mastomys coucha (southern multimammate mouse): 116077461
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Entry
116077461 CDS
T07224
Symbol
Top2a
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
mcoc
Mastomys coucha (southern multimammate mouse)
Pathway
mcoc01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
mcoc00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
116077461 (Top2a)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
mcoc03032
]
116077461 (Top2a)
03036 Chromosome and associated proteins [BR:
mcoc03036
]
116077461 (Top2a)
Enzymes [BR:
mcoc01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
116077461 (Top2a)
DNA replication proteins [BR:
mcoc03032
]
Eukaryotic type
DNA Topoisomerases
116077461 (Top2a)
Chromosome and associated proteins [BR:
mcoc03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
116077461 (Top2a)
Centrosome formation proteins
Centriole proteins
116077461 (Top2a)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
116077461
NCBI-ProteinID:
XP_031207885
LinkDB
All DBs
Position
Unknown
AA seq
1527 aa
AA seq
DB search
MELSPLQPVNENMLMNKKKNEDGKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQM
WVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNN
GKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVET
ASREYKKMFKQTWMDNMGRAGDMELKPFSGEDYTCITFQPDLSKFKMQSLDKDIVALMVR
RAYDIAGSTKDVKVFLNGNRLPIKGFRSYVDMYLKDKVDETGNSLKVVHEQVNPRWEVCL
TMSEKGFQQISFVNSIATSKGGRHVDYIADQIVSKLVDVVKKKNKGGVAVKAHQVKNHMW
IFVNALIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQI
QLNKKCSAVKHNKIKGIPKLDDANDAGSRNSTECTLILTEGDSAKTLAVSGLGVVGRDKY
GVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTD
QDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKSS
TPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQVDDR
KEWLTNFMQDRRQRKLLGLPDDYLYGQSTSYLTYNDFINKELILFSNSDNERSIPSMVDG
LKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNL
NLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLRFLYDDNQRVEPEWY
IPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLLDGEEPLPMLPSYKNFKGTIEE
LASNQYVINGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYKEYH
TDTTVKFVIKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILRD
FFELRLKYYGLRKEWLLGMLGAESSKLNNQARFILEKIDGKIVIENKPKKELIKVLIQRG
YDSDPVKAWKEAQQKVPDEEENEESDSETSTSDSAAESGPTFNYLLDMPLWYLTKEKKDE
LCKQRNEKEQELNTLKKKSPSDLWKEDLAVFIEELEVVEAKEKQDELVGLPGKGGKAKGK
KAQMTEVLPSPMGKRVIPQVTVEMKAEAEKKIRKKIKSENVEGTPTEDGAETGSLRQRLE
KKQKREPGTMAKKQTTLPFKPIKKGKKKNPWSDSESDMSSNESNFDVPPREKEQRSAAAK
AKFTVDLDSSEDFSGSDENEDFLPLDATPPKTKIPPKNTKKALKPQNREATAVVDLESDV
KDNVPASPGAPAADFPAETEHLKPTSKKTVGVKKTATKSQSTVSIAGTKKRAASKVTKSD
PALNVGASEKPAPAKAKNSRKRKPSSSDSSDSDFEKAISKGATSKKPKGEEQDFHVDLED
TVAPRAKSGRARKPIKYLEESDDDDLF
NT seq
4584 nt
NT seq
+upstream
nt +downstream
nt
atggagttgtcaccactgcagcctgtaaatgaaaatatgctaatgaacaaaaagaagaat
gaagatggcaagaaaagattgtctattgaaagaatctatcagaaaaaaacacaactggag
catatactgctccgcccagacacctacattggctctgtggagttagtgacccagcaaatg
tgggtttacgatgaagatgttggcattaactacagggaagtcacttttgttcctggtttg
tataaaatctttgatgagattctagttaatgctgctgataacaaacaaagggacccaaaa
atgtcttgtattagagtcacaattgatccagaaaataatttaattagtatctggaataat
ggaaaaggaattcctgttgttgaacacaaagttgagaaaatgtatgtcccagctctcata
tttggacagcttctgacttccagtaactatgatgatgatgagaagaaagtgacaggtggt
cgaaatggctatggagctaaactctgtaatatattcagcaccaaatttactgtggaaaca
gccagtagagaatacaagaaaatgttcaaacagacatggatggataacatgggaagagct
ggtgacatggaactcaagccctttagtggagaagattatacatgtattaccttccagcct
gacttatctaagtttaaaatgcaaagtctggacaaagacattgttgcgttgatggtcaga
agagcatatgacatcgctggttccactaaagatgtcaaagtctttcttaatggaaatagg
ctgccaataaaagggttccgtagttatgtggatatgtatttgaaggataaggtagatgaa
actgggaactcactgaaggtggtacatgaacaagtaaatccccggtgggaagtgtgctta
acaatgagcgagaaaggctttcagcagattagcttcgtcaacagcattgctacttctaag
ggtggcaggcatgttgattacatagctgatcagattgtgagcaaactcgttgatgtggtg
aaaaagaagaacaagggcggtgttgcagtgaaggctcatcaggtgaaaaatcacatgtgg
atttttgtaaatgccttaattgaaaacccaacctttgactctcaaacaaaagaaaacatg
actttacaagccaagagctttggatcaacatgtcaattaagtgagaagttcatcaaagct
gcaattggttgtggtattgtcgaaagcatactcaactgggtgaaatttaaggctcaaatc
caattaaacaagaagtgttcagctgtaaaacataacaaaatcaagggaatccccaaactt
gatgatgccaatgatgcagggagccgaaattctactgaatgcacacttatcctgactgag
ggagactcagcaaaaactctggcagtttctggccttggagtggttggaagagacaaatat
ggggtgttccctctcagggggaaaatactcaatgtgcgagaagcttctcataaacagatc
atggaaaatgctgaaattaacaatatcatcaagattgtgggtcttcagtacaagaaaaac
tatgaagatgaagattcattgaaaactcttcgttatgggaagatcatgattatgacagat
caggatcaagatggttcccatatcaaaggcttgctgatcaattttatccatcacaattgg
ccatctcttctgcgacatcgttttctagaagaatttatcactcccattgtaaaggtgtcc
aaaaataagcaagaaatggcattctatagtcttcccgagtttgaagaatggaagagttca
actccaaatcataaaaaatggaaagtcaaatactacaaaggtttgggcaccagcacatca
aaggaagctaaggaatattttgcagatatgaaacgacatcgtattcaattcaaatactct
ggccctgaagatgatgctgcaatcagcctggcctttagtaaaaaacaagtggatgaccga
aaggaatggttaactaatttcatgcaagacagaagacaacggaagttacttggcctgcct
gatgattatttgtatggacaaagcacttcgtacctgacctataatgacttcataaacaag
gaacttatcctcttttcaaactctgataatgaaagatctatcccatctatggtagatggt
ttgaaaccaggtcagagaaaggttttgttcacttgtttcaaacgaaatgacaagcgagaa
gtgaaggttgcccagttagctgggtcagtggcagaaatgtcctcttatcaccatggtgag
atgtcactgatgatgaccattatcaatttggctcagaattttgtgggtagcaataacttg
aaccttttacagcccattggtcagtttggtaccaggctgcatggtggcaaggactcagct
agtcctaggtacatctttacaatgctcagctctttggctcggttgttgtttccaccaaaa
gatgatcacacgttacggtttctatatgatgacaaccagcgtgttgagcctgaatggtac
attcccattatacccatggtgctgataaatggtgctgagggtattggtactgggtggtcc
tgcaaaattcccaactttgatgttcgtgaagtcgtaaataatatcagacggcttttagat
ggagaagagcctctgcccatgcttccaagttataagaatttcaaaggtactattgaagaa
ctggcttcaaatcagtatgtgattaatggagaagtagctattctgaattctacaaccatt
gagatctcagagcttcccatcagaacatggacccaaacatataaagaacaggttctagaa
cccatgttgaatggcactgagaagacaccccctctaataacagactacaaggaataccat
actgataccactgtgaagtttgtcataaagatgactgaagaaaaattggcagaggcagag
agagttggactacacaaagtcttcaaactccagactagtctcacttgcaactctatggtg
ctttttgaccatgtaggttgcttaaagaaatatgacactgtgctggatattctaagagac
ttctttgagctcagacttaaatattatggattaagaaaagaatggcttctaggaatgctt
ggtgcagagtcttctaaactgaataatcaagctcgctttatattagagaaaatagatggc
aaaatagtcattgaaaataaacctaaaaaagaattaattaaagttttgattcagagagga
tacgattctgaccctgtgaaagcctggaaagaagctcaacaaaaggtcccagatgaagag
gaaaatgaagaaagtgactctgaaactagcaccagtgactctgcagccgagtctggccca
accttcaactacctgctcgacatgcccctgtggtaccttaccaaggagaagaaggacgag
ctgtgcaagcaaagaaacgagaaggaacaagagctcaacacattaaagaaaaagagtcca
tcggacttgtggaaggaagatctggctgtttttattgaagaactggaggttgtggaagcc
aaggaaaaacaggatgaactagtaggacttcctggaaaggggggaaaagcaaaggggaag
aaagcacagatgactgaagtcctgccttctcctatgggaaaaagagtcattccccaagtg
actgtagagatgaaggctgaggccgagaagaaaattaggaagaaaattaagagtgaaaat
gttgagggtacccctactgaggatggtgctgaaacaggaagcctacggcaacgattagag
aagaagcagaagagagagccaggcaccatggcaaagaagcaaactacattgccgtttaaa
cctatcaaaaaagggaaaaagaaaaacccctggtctgattctgagtcagatatgagcagt
aatgaaagtaattttgatgtccctccgcgagaaaaagagcaaagaagtgctgcagcgaaa
gccaaattcacagtggatttagactccagtgaagatttctcaggttcagatgaaaatgaa
gatttcctcccattagatgctactccacctaagaccaaaatccccccaaaaaatactaag
aaagcactgaagccacagaaccgtgaagccacagcagtagttgatcttgaaagtgatgtc
aaggacaatgtgccagcttctcctggtgcccctgctgctgacttcccagctgaaactgaa
cacttaaagccaacctccaaaaagactgtgggagtgaagaagacagcaaccaaaagccag
tctacagtctccattgctggtaccaaaaagagagctgcatcgaaggtaaccaaatcagac
ccagccctgaatgtgggtgcctctgaaaagcctgctcctgccaaagccaagaacagtcgc
aaaaggaagccatcttcttctgatagctctgactctgattttgagaaagcaatttctaaa
ggtgccacaagcaagaaaccaaagggagaggaacaggatttccatgtggacttagaagac
actgtggctcctcgagccaaatctggacgagcaaggaagccaattaagtacctggaggag
tctgatgatgatgacctcttctga
DBGET
integrated database retrieval system
