Mastomys coucha (southern multimammate mouse): 116077605
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Entry
116077605 CDS
T07224
Symbol
Erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
mcoc
Mastomys coucha (southern multimammate mouse)
Pathway
mcoc01521
EGFR tyrosine kinase inhibitor resistance
mcoc01522
Endocrine resistance
mcoc01524
Platinum drug resistance
mcoc04010
MAPK signaling pathway
mcoc04012
ErbB signaling pathway
mcoc04020
Calcium signaling pathway
mcoc04066
HIF-1 signaling pathway
mcoc04151
PI3K-Akt signaling pathway
mcoc04510
Focal adhesion
mcoc04518
Integrin signaling
mcoc04520
Adherens junction
mcoc04530
Tight junction
mcoc05200
Pathways in cancer
mcoc05205
Proteoglycans in cancer
mcoc05206
MicroRNAs in cancer
mcoc05212
Pancreatic cancer
mcoc05213
Endometrial cancer
mcoc05215
Prostate cancer
mcoc05219
Bladder cancer
mcoc05223
Non-small cell lung cancer
mcoc05224
Breast cancer
mcoc05226
Gastric cancer
mcoc05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mcoc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
116077605 (Erbb2)
04012 ErbB signaling pathway
116077605 (Erbb2)
04066 HIF-1 signaling pathway
116077605 (Erbb2)
04020 Calcium signaling pathway
116077605 (Erbb2)
04151 PI3K-Akt signaling pathway
116077605 (Erbb2)
09133 Signaling molecules and interaction
04518 Integrin signaling
116077605 (Erbb2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
116077605 (Erbb2)
04520 Adherens junction
116077605 (Erbb2)
04530 Tight junction
116077605 (Erbb2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
116077605 (Erbb2)
05206 MicroRNAs in cancer
116077605 (Erbb2)
05205 Proteoglycans in cancer
116077605 (Erbb2)
05230 Central carbon metabolism in cancer
116077605 (Erbb2)
09162 Cancer: specific types
05212 Pancreatic cancer
116077605 (Erbb2)
05226 Gastric cancer
116077605 (Erbb2)
05219 Bladder cancer
116077605 (Erbb2)
05215 Prostate cancer
116077605 (Erbb2)
05213 Endometrial cancer
116077605 (Erbb2)
05224 Breast cancer
116077605 (Erbb2)
05223 Non-small cell lung cancer
116077605 (Erbb2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
116077605 (Erbb2)
01524 Platinum drug resistance
116077605 (Erbb2)
01522 Endocrine resistance
116077605 (Erbb2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcoc01001
]
116077605 (Erbb2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mcoc04147
]
116077605 (Erbb2)
04090 CD molecules [BR:
mcoc04090
]
116077605 (Erbb2)
Enzymes [BR:
mcoc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
116077605 (Erbb2)
Protein kinases [BR:
mcoc01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
116077605 (Erbb2)
Exosome [BR:
mcoc04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
116077605 (Erbb2)
CD molecules [BR:
mcoc04090
]
Proteins
116077605 (Erbb2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Haspin_kinase
Kinase-like
EphA2_TM
Tcell_CD4_C
GAPT
PDGLE
Motif
Other DBs
NCBI-GeneID:
116077605
NCBI-ProteinID:
XP_031208122
LinkDB
All DBs
Position
Unknown
AA seq
1289 aa
AA seq
DB search
MELAAWCRWGFLLALLPPGAAGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLPANASLSFLQDIQEVQGYMLIAHNRVKHVPLQRLRIVRGTQLFEDKYALAVLDNR
DPLDNSTTVAPGRIPEGLRELQLRSLTEILKGGVLIRGNPQLCYQDVILWKDVFRKNNQL
APVDVDTNRSRACPPCSPTCKDNHCWGESPEDCQILTGTICTSGCARCKGRLPTDCCHEQ
CAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMLNPEGRYTFGASCVTTC
PYNYLSTEVGSCTLVCPPNNQEITAEDGTQRCEKCSKPCARVCYGLGMEHLRGARAITSD
NIQEFTGCKKIFGSLAFLPESFDGNPSSGIAPLKPEHLQVFETLEEITGYLYISAWPESL
HDLSVFQNLRVIRGRILHDGAYSLTLQGLGIHSLGLRSLRELGSGLALIHRNTHLCFVHT
VPWDQLFRNPHQALLHSGNRPEEECGLEGLVCNSLCSHGHCWGPGPTQCVNCTQFLRGQE
CVEECRVWKGLPREYVSDKHCLPCHPECQPQNSSETCFGSEADQCAACAHYKDSSFCVAR
CPSGVKPDLSYMPIWKYPDEEGICQPCPINCTHSCVDLDERGCPAEQRASPVTFIIATVV
GVLLFLIIVVVVGILIKRRRQKIRKYTMRRLLQETEVRHGKGLLVLPHPQPQALQLPQHG
THPTTLSLQLVEPLTPSGAVPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENV
KIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCL
LDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGL
ARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGI
PAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRF
VVIQNEDLGPSSPMDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFSPDPAPGTGSTAHRR
HRSSSTRSGGGELTLGLEPPEEDPPRSPLAPSEGAGSDVFDGDLAVGVTKGLQSLSPHDL
SPLQRYSEDPTLPLPPETDGYVAPLACSPQPEYVNQPEVRPQPPLTPEGPPPPVRPGGAT
LERPKTLSPGKNGVVKDVFAFGGAVENPEYLAPREGTASQPHPSPAFSPAFDNLYYWDQN
SSEQGPPPSTFEGTPTAENPEYLGLDVPV
NT seq
3870 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgttgggggttcctcctcgccctcctgccccccggagcc
gcgggtacccaagtgtgtaccggcacagacatgaagttgcggctccctgccagtcctgag
acccacctggacatgcttcgccacctctaccagggctgtcaggtggtgcagggcaacttg
gaacttacctacctgcctgccaatgccagcctctcattcctgcaggacatccaggaagtc
cagggatacatgctcatcgctcacaaccgagtgaagcacgtcccactacaaaggttgcgc
atcgtgagagggacccaactctttgaggacaagtatgccctggctgtgctagacaacaga
gatcctttggacaatagcaccaccgtcgccccaggcagaatcccagaagggcttcgggag
ctgcagcttcgaagtctcacagagatcctgaagggaggagttttgatccgtgggaaccct
cagctctgctaccaggacgtgattttgtggaaggatgtcttccgcaagaataaccagttg
gctcctgtcgatgtagacaccaatcgttcccgggcctgtccaccttgctctccaacctgc
aaagataatcactgttggggtgagagtcctgaagactgtcagatcttgactggcaccatc
tgtaccagtggctgtgcccggtgcaagggccggctgcccactgactgttgccacgaacaa
tgtgctgcaggctgcacgggccccaaacattcggactgcctggcctgcctccacttcaac
catagcggtatctgtgagctgcattgcccagccctcgtcacctacaacacagacactttc
gagtccatgctcaaccctgagggtcgttacacctttggtgccagctgtgtgaccacctgc
ccctacaactacctctctacggaagtgggatcctgcactctggtctgtcccccgaataac
caagagatcacagctgaggacggaacacagcggtgtgagaaatgcagcaagccctgtgct
cgagtgtgctatggtctgggcatggagcatcttcgaggggcgagggccatcaccagtgac
aatatccaggagttcactggctgcaagaagatctttgggagcctggcatttttgccggag
agctttgacgggaacccctcctcgggcattgccccactgaagcctgagcatctccaagtg
ttcgaaaccctggaggagattacaggttacctatacatttcagcatggccagagagcctc
catgacctcagcgttttccagaaccttcgggtcattcggggacggattctccatgacggt
gcctactccttgacactgcaaggtctgggaattcactcgctggggctgcgctcactgcgg
gagcttggcagtggattggctctcattcaccgcaacacccatctctgctttgtacacact
gtaccttgggatcagctcttccggaacccgcaccaggccctgctccacagtgggaaccgg
ccggaagaggaatgtggtctcgagggcttggtctgtaactcactgtgttcccatgggcac
tgctgggggccagggcccacccagtgtgtcaactgcactcagttcctccggggccaggag
tgtgtggaggagtgtcgagtatggaaggggctccccagggagtatgtgagtgacaagcac
tgtctgccatgccaccctgagtgtcagcctcaaaacagctctgagacctgctttggatcg
gaggctgaccagtgcgcagcttgtgcccactacaaggattcatccttctgtgtggctcgc
tgccccagtggtgtgaaaccagacctctcctacatgcccatttggaagtacccggatgag
gagggcatatgtcagccatgccccatcaactgcacccactcttgtgtggacctggatgaa
cgaggctgcccagcagagcagagagccagcccagtgacattcatcattgcaactgtggtg
ggcgtcctgttgttcctgatcatagtggtggtcgttggaatcctaatcaaacgaaggcga
cagaagatccggaagtatacaatgcgtaggctgctgcaggaaactgaggtgagacatggc
aagggcctcctagtgctcccccacccccaaccccaagctttgcagcttcctcagcatggc
actcaccctaccaccctctccctccagctagtggagccgctgacgcccagtggagccgtg
cccaaccaggctcagatgaggatcctgaaagagacggagctaaggaaggtgaaggtgctt
ggatcaggagctttcggcactgtctacaagggcatctggatcccagatggggagaatgtg
aaaatccccgtggccatcaaggtgttgagggaaaacacatctcctaaagctaacaaagaa
atcctagatgaagcttatgtgatggctggtgtgggttctccctatgtgtcccgcctcctg
ggcatctgcctgacatccacagtgcagctggtgacacagcttatgccctatggttgcctt
ctggaccatgtccgagaacaccgaggtcgcctaggctcccaggacctgctcaactggtgt
gttcagatcgccaaggggatgagctacctggaggatgtgcggctcgttcacagggacctc
gctgcccggaacgtgctcgtcaagagtcccaatcacgtcaagattacagacttcgggctg
gctcggctgctggacattgatgagacagaataccatgcagatgggggcaaggtacccatc
aagtggatggcattggaatctattcttagacgccggttcacccatcagagtgatgtgtgg
agctatggcgtgactgtgtgggagctgatgacttttggggccaaaccttacgatgggatc
ccagcccgggagatccctgatttgctggagaagggagaacgcctacctcagcctccaatc
tgcaccatcgatgtctacatgatcatggtcaaatgttggatgattgactctgaatgtcgt
ccgagattccgggagttggtatcagaattctcccgtatggcgagagaccctcagcgcttt
gtggtcatccagaacgaggacttgggcccctccagccccatggacagcaccttctaccgt
tcactgctggaggatgatgacatgggggatctggtcgatgctgaagagtatctggtaccc
cagcagggatttttctccccagaccctgccccaggcactgggagcacagcccaccgcaga
caccgcagctcatccaccaggagtggaggtggtgagctgacactgggcctggagccccct
gaagaagatccccccagatctccactggctccctccgaaggggctggctccgacgtgttt
gatggtgacctggcagtgggggtaaccaaagggctgcagagcctctctccacatgacctc
agccctctacagcggtacagcgaggatcccacgttacctctgcccccggagactgatggc
tacgttgctcccctggcctgcagcccccagcccgagtatgtgaaccagccagaggttcga
cctcagcctcccttgaccccagagggtcctccgcctcctgtccgacctgggggtgctact
ttagaaagacccaagaccctctctcctgggaagaatggggttgtcaaagacgtttttgcc
tttgggggtgctgtggagaaccctgaatacttagcacccagagaaggcaccgcctctcag
ccccacccttctcctgccttcagcccagcctttgacaacctctattattgggaccagaac
tcatcggaacaggggcctccaccaagtacctttgaagggacccccactgcagagaaccct
gagtacctaggcctggatgtgccagtatga
DBGET
integrated database retrieval system
