KEGG   Mastomys coucha (southern multimammate mouse): 116078408
Entry
116078408         CDS       T07224                                 
Symbol
Socs3
Name
(RefSeq) suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
mcoc  Mastomys coucha (southern multimammate mouse)
Pathway
mcoc04120  Ubiquitin mediated proteolysis
mcoc04380  Osteoclast differentiation
mcoc04630  JAK-STAT signaling pathway
mcoc04668  TNF signaling pathway
mcoc04910  Insulin signaling pathway
mcoc04917  Prolactin signaling pathway
mcoc04920  Adipocytokine signaling pathway
mcoc04930  Type II diabetes mellitus
mcoc04931  Insulin resistance
mcoc04932  Non-alcoholic fatty liver disease
mcoc04935  Growth hormone synthesis, secretion and action
mcoc05160  Hepatitis C
mcoc05164  Influenza A
mcoc05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:mcoc00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    116078408 (Socs3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    116078408 (Socs3)
   04668 TNF signaling pathway
    116078408 (Socs3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    116078408 (Socs3)
   04920 Adipocytokine signaling pathway
    116078408 (Socs3)
   04917 Prolactin signaling pathway
    116078408 (Socs3)
   04935 Growth hormone synthesis, secretion and action
    116078408 (Socs3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    116078408 (Socs3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    116078408 (Socs3)
   05164 Influenza A
    116078408 (Socs3)
   05168 Herpes simplex virus 1 infection
    116078408 (Socs3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    116078408 (Socs3)
   04932 Non-alcoholic fatty liver disease
    116078408 (Socs3)
   04931 Insulin resistance
    116078408 (Socs3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:mcoc04121]
    116078408 (Socs3)
Ubiquitin system [BR:mcoc04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     116078408 (Socs3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 116078408
NCBI-ProteinID: XP_031209470
LinkDB
Position
Unknown
AA seq 225 aa
MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLL
SAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV
LKLVHHYMPPPGTPSFSLPPTEPSSEVPEQPPAQALPGSTPKRAYYIYSGGEKIPLVLSR
PLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
NT seq 678 nt   +upstreamnt  +downstreamnt
atggtcacccacagcaagtttcccgccgccgggatgagccgccccctggacaccagcctg
cgcctcaagaccttcagctccaagagcgagtaccagctggtggtgaacgccgtgcgcaag
ctgcaggagagcggattctactggagcgccgtgaccggcggcgaggcgaacctgctgctc
agcgccgagcccgcgggcacctttcttatccgcgacagctcggaccagcgccacttcttc
acgctgagcgtcaagacccagtcggggaccaagaacctgcgcatccagtgtgaggggggc
agcttttcgctgcagagtgacccccggagcacgcagccagtaccccgcttcgactgtgta
ctcaagctggtgcaccactacatgccgcccccagggaccccctccttctctttgccaccc
acggaaccctcctctgaggttccggagcagccacctgcccaggcactccccgggagtacc
cccaagagagcttactacatctattctgggggcgagaagattccgctggtactgagccga
cctctctcctccaatgtggccaccctccagcacctttgtcggaagactgtcaacggccac
ctggactcctatgagaaagtgacccagctgcctggacccatccgggagttcctggaccag
tatgatgctccgctttaa

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