Mastomys coucha (southern multimammate mouse): 116085336
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Entry
116085336 CDS
T07224
Symbol
Mapk8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
KO
K04440
mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:
2.7.11.24
]
Organism
mcoc
Mastomys coucha (southern multimammate mouse)
Pathway
mcoc01522
Endocrine resistance
mcoc04010
MAPK signaling pathway
mcoc04012
ErbB signaling pathway
mcoc04014
Ras signaling pathway
mcoc04024
cAMP signaling pathway
mcoc04068
FoxO signaling pathway
mcoc04071
Sphingolipid signaling pathway
mcoc04137
Mitophagy - animal
mcoc04140
Autophagy - animal
mcoc04141
Protein processing in endoplasmic reticulum
mcoc04210
Apoptosis
mcoc04215
Apoptosis - multiple species
mcoc04217
Necroptosis
mcoc04310
Wnt signaling pathway
mcoc04380
Osteoclast differentiation
mcoc04510
Focal adhesion
mcoc04517
IgSF CAM signaling
mcoc04519
Cadherin signaling
mcoc04530
Tight junction
mcoc04620
Toll-like receptor signaling pathway
mcoc04621
NOD-like receptor signaling pathway
mcoc04622
RIG-I-like receptor signaling pathway
mcoc04625
C-type lectin receptor signaling pathway
mcoc04657
IL-17 signaling pathway
mcoc04658
Th1 and Th2 cell differentiation
mcoc04659
Th17 cell differentiation
mcoc04660
T cell receptor signaling pathway
mcoc04664
Fc epsilon RI signaling pathway
mcoc04668
TNF signaling pathway
mcoc04722
Neurotrophin signaling pathway
mcoc04723
Retrograde endocannabinoid signaling
mcoc04728
Dopaminergic synapse
mcoc04750
Inflammatory mediator regulation of TRP channels
mcoc04910
Insulin signaling pathway
mcoc04912
GnRH signaling pathway
mcoc04914
Progesterone-mediated oocyte maturation
mcoc04917
Prolactin signaling pathway
mcoc04920
Adipocytokine signaling pathway
mcoc04926
Relaxin signaling pathway
mcoc04930
Type II diabetes mellitus
mcoc04931
Insulin resistance
mcoc04932
Non-alcoholic fatty liver disease
mcoc04933
AGE-RAGE signaling pathway in diabetic complications
mcoc04935
Growth hormone synthesis, secretion and action
mcoc04936
Alcoholic liver disease
mcoc05010
Alzheimer disease
mcoc05012
Parkinson disease
mcoc05016
Huntington disease
mcoc05017
Spinocerebellar ataxia
mcoc05020
Prion disease
mcoc05022
Pathways of neurodegeneration - multiple diseases
mcoc05132
Salmonella infection
mcoc05133
Pertussis
mcoc05135
Yersinia infection
mcoc05142
Chagas disease
mcoc05145
Toxoplasmosis
mcoc05152
Tuberculosis
mcoc05161
Hepatitis B
mcoc05162
Measles
mcoc05166
Human T-cell leukemia virus 1 infection
mcoc05167
Kaposi sarcoma-associated herpesvirus infection
mcoc05169
Epstein-Barr virus infection
mcoc05170
Human immunodeficiency virus 1 infection
mcoc05171
Coronavirus disease - COVID-19
mcoc05200
Pathways in cancer
mcoc05208
Chemical carcinogenesis - reactive oxygen species
mcoc05210
Colorectal cancer
mcoc05212
Pancreatic cancer
mcoc05231
Choline metabolism in cancer
mcoc05415
Diabetic cardiomyopathy
mcoc05417
Lipid and atherosclerosis
mcoc05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mcoc00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
116085336 (Mapk8)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
116085336 (Mapk8)
04012 ErbB signaling pathway
116085336 (Mapk8)
04014 Ras signaling pathway
116085336 (Mapk8)
04310 Wnt signaling pathway
116085336 (Mapk8)
04668 TNF signaling pathway
116085336 (Mapk8)
04068 FoxO signaling pathway
116085336 (Mapk8)
04071 Sphingolipid signaling pathway
116085336 (Mapk8)
04024 cAMP signaling pathway
116085336 (Mapk8)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
116085336 (Mapk8)
04519 Cadherin signaling
116085336 (Mapk8)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
116085336 (Mapk8)
04137 Mitophagy - animal
116085336 (Mapk8)
09143 Cell growth and death
04210 Apoptosis
116085336 (Mapk8)
04215 Apoptosis - multiple species
116085336 (Mapk8)
04217 Necroptosis
116085336 (Mapk8)
09144 Cellular community - eukaryotes
04510 Focal adhesion
116085336 (Mapk8)
04530 Tight junction
116085336 (Mapk8)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
116085336 (Mapk8)
04621 NOD-like receptor signaling pathway
116085336 (Mapk8)
04622 RIG-I-like receptor signaling pathway
116085336 (Mapk8)
04625 C-type lectin receptor signaling pathway
116085336 (Mapk8)
04660 T cell receptor signaling pathway
116085336 (Mapk8)
04658 Th1 and Th2 cell differentiation
116085336 (Mapk8)
04659 Th17 cell differentiation
116085336 (Mapk8)
04657 IL-17 signaling pathway
116085336 (Mapk8)
04664 Fc epsilon RI signaling pathway
116085336 (Mapk8)
09152 Endocrine system
04910 Insulin signaling pathway
116085336 (Mapk8)
04920 Adipocytokine signaling pathway
116085336 (Mapk8)
04912 GnRH signaling pathway
116085336 (Mapk8)
04914 Progesterone-mediated oocyte maturation
116085336 (Mapk8)
04917 Prolactin signaling pathway
116085336 (Mapk8)
04926 Relaxin signaling pathway
116085336 (Mapk8)
04935 Growth hormone synthesis, secretion and action
116085336 (Mapk8)
09156 Nervous system
04728 Dopaminergic synapse
116085336 (Mapk8)
04723 Retrograde endocannabinoid signaling
116085336 (Mapk8)
04722 Neurotrophin signaling pathway
116085336 (Mapk8)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
116085336 (Mapk8)
09158 Development and regeneration
04380 Osteoclast differentiation
116085336 (Mapk8)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
116085336 (Mapk8)
05208 Chemical carcinogenesis - reactive oxygen species
116085336 (Mapk8)
05231 Choline metabolism in cancer
116085336 (Mapk8)
09162 Cancer: specific types
05210 Colorectal cancer
116085336 (Mapk8)
05212 Pancreatic cancer
116085336 (Mapk8)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
116085336 (Mapk8)
05170 Human immunodeficiency virus 1 infection
116085336 (Mapk8)
05161 Hepatitis B
116085336 (Mapk8)
05171 Coronavirus disease - COVID-19
116085336 (Mapk8)
05162 Measles
116085336 (Mapk8)
05167 Kaposi sarcoma-associated herpesvirus infection
116085336 (Mapk8)
05169 Epstein-Barr virus infection
116085336 (Mapk8)
09171 Infectious disease: bacterial
05132 Salmonella infection
116085336 (Mapk8)
05135 Yersinia infection
116085336 (Mapk8)
05133 Pertussis
116085336 (Mapk8)
05152 Tuberculosis
116085336 (Mapk8)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
116085336 (Mapk8)
05142 Chagas disease
116085336 (Mapk8)
09164 Neurodegenerative disease
05010 Alzheimer disease
116085336 (Mapk8)
05012 Parkinson disease
116085336 (Mapk8)
05016 Huntington disease
116085336 (Mapk8)
05017 Spinocerebellar ataxia
116085336 (Mapk8)
05020 Prion disease
116085336 (Mapk8)
05022 Pathways of neurodegeneration - multiple diseases
116085336 (Mapk8)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
116085336 (Mapk8)
05418 Fluid shear stress and atherosclerosis
116085336 (Mapk8)
05415 Diabetic cardiomyopathy
116085336 (Mapk8)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
116085336 (Mapk8)
04936 Alcoholic liver disease
116085336 (Mapk8)
04932 Non-alcoholic fatty liver disease
116085336 (Mapk8)
04931 Insulin resistance
116085336 (Mapk8)
04933 AGE-RAGE signaling pathway in diabetic complications
116085336 (Mapk8)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
116085336 (Mapk8)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcoc01001
]
116085336 (Mapk8)
Enzymes [BR:
mcoc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
116085336 (Mapk8)
Protein kinases [BR:
mcoc01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
116085336 (Mapk8)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kdo
ABC1
RIO1
Kinase-like
FTA2
APH
Motif
Other DBs
NCBI-GeneID:
116085336
NCBI-ProteinID:
XP_031218729
LinkDB
All DBs
Position
Unknown
AA seq
427 aa
AA seq
DB search
MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAMINGSQHPSSSPSVNDMSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq
1284 nt
NT seq
+upstream
nt +downstream
nt
atgagcagaagcaaacgtgacaacaatttttatagtgtagagattggagattctacattc
acagtcctaaaacgataccagaatttaaagcctataggctcaggagctcaaggaatagtg
tgtgcagcttatgatgccattcttgaaagaaatgttgcgatcaagaagctcagccggcca
tttcagaatcagactcatgctaagcgagcctaccgagaactagttcttatgaagtgtgtt
aatcacaaaaatataattggccttttgaatgttttcacaccacagaaatccctagaagaa
tttcaagatgtttacatagtcatggagctcatggatgcaaatctttgccaagtgattcag
atggagttagatcatgaaagaatgtcctaccttctctatcaaatgctgtgtggaatcaag
caccttcactctgctggaattattcatcgggacttaaagcctagtaatatagtagtcaaa
tcagactgcactttgaagattcttgattttggactggcgaggactgcaggaacgagtttt
atgatgacaccttacgtggttactcgctactacagagcaccagaggtcattctcggcatg
ggctacaaggagaacgtggatttatggtctgtggggtgcattatgggagaaatggtttgc
cacaaaatcctctttccaggaagggactatattgatcagtggaataaagttattgaacag
cttggaacaccttgtcctgaattcatgaagaaactacaaccaacagtaaggacttacgtt
gaaaatagacctaaatatgctggatacagctttgagaaactattccctgatgtgcttttc
ccagctgactcagagcataacaaacttaaagccagtcaggccagagatttgttatccaaa
atgctagtaatagatgcatccaaaagaatctccgtagatgaagctctccagcacccgtac
atcaacgtctggtatgatccttcagaagcagaagccccaccaccaaagatccctgacaag
cagttagatgaaagggagcacacaatagaggagtggaaagaactgatatacaaggaggta
atggatttggaggagcgaactaagaatggagtcataagagggcagccatctcctttaggt
gcagcaatgatcaatggctctcagcatccatcgtcttcgccgtctgtcaatgacatgtct
tcaatgtccacagatccgactttggcctcggatacagacagcagcctagaagcatcagcc
ggacctctgggctgctgtagatga
DBGET
integrated database retrieval system