Mastomys coucha (southern multimammate mouse): 116086139
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Entry
116086139 CDS
T07224
Symbol
Gart
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
mcoc
Mastomys coucha (southern multimammate mouse)
Pathway
mcoc00230
Purine metabolism
mcoc00670
One carbon pool by folate
mcoc01100
Metabolic pathways
mcoc01523
Antifolate resistance
Module
mcoc_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mcoc00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
116086139 (Gart)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
116086139 (Gart)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
116086139 (Gart)
Enzymes [BR:
mcoc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
116086139 (Gart)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
116086139 (Gart)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
116086139 (Gart)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_3
CPSase_L_D2
Dala_Dala_lig_C
ATP-grasp_4
ATP-grasp_2
Motif
Other DBs
NCBI-GeneID:
116086139
NCBI-ProteinID:
XP_031220262
LinkDB
All DBs
Position
Unknown
AA seq
1010 aa
AA seq
DB search
MAARVLVIGSGGREHMLAWKLAQSPHVKQVLVAPGNAGTACSGKISNAAVSVRDHTALAH
FCKEEKIELVVVGPEAPLAAGIVGDLTSAGVRCFGPTAQAAQLESSKKFAKEFMDRHGIP
TAQWRAFTNPEDACSFIMSASFPALVVKASGLAAGKGVIVAKSQGEACRAVQEIMQEKSF
GAAGETVVVEEFLEGEEVSCLCFTDGKTVAAMPPAQDHKRLLDGDQGPNTGGMGAYCPAP
QVSKDLLVKIKNTILQRTVDGMQQEGAPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTFDGLLSTSLPVWLENHSAVTVVMASAGYPGAYTKGVEITGFPEA
QALGLQVFHAGTALKDGKVVTSGGRVLAVTAVQENLLSALEEARKGLAALKFEGAVYRKD
IGFHAVAFLQQPRGLTYKDSGVDIAAGNMLVKKIQPLAKATSRPGCSVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCNKHDSIGQDLVAMCVNDILAQGAEPLFFLDYFAC
GKLDLSTTEAVVAGIAAACRQAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERHQKLP
QLERIAEGDAVIGVASSGLHSNGFSLVRKIVERSSLQYSSPAPGACGGQTLGDLLLTPTR
IYSHSLLPIIRSGRVKAFAHITGGGLLENIPRVLPQKFGVDLDACTWRVPKVFSWLQQEG
QLSEEEMARTFNCGVGAALVVSKDQTEQILYDIRQHQEEAWVIGSVVARPEDSPRVRVKN
LIETIQTNESVVANGFLRSNFPVQQKKARVAVLISGTGSNLQALIDSTRDPKSSSHIVLV
ISNKAAVAGLDRAEQAGIPTRVINHKLYKNRVEFDNAIDCVLEEFSVDIVCLAGFMRILS
GPFVRKWDGKMLNIHPSLLPSFKGSNAHEQVLEAGVTITGCTVHFVAEDVDAGQIILQEA
VPVQRSDTVATLSERVKVAEHKIFPAALQLVASGTVQLREDGRIHWASEL
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagttcttgtaattggtagtggaggaagggaacatatgctggcctggaaa
cttgcacagtcgcctcacgtcaagcaagtgttggttgccccaggaaatgcaggcaccgct
tgctctgggaagatctccaatgctgctgtctctgtcagggatcacactgcccttgcccac
ttctgcaaagaggaaaagattgaacttgtagttgtcggaccagaggcccctctggctgca
ggaattgttggggacctgacctctgcaggagtgcgatgctttggccccacagcacaagca
gctcaactggagtccagtaaaaagtttgccaaagagtttatggaccgccatggaatccca
actgcgcagtggagagcattcaccaatcctgaggatgcctgcagctttattatgagtgcc
agctttccggctttggttgtgaaggccagtggccttgcagcaggaaagggggtgattgtg
gcaaagagccaaggggaagcctgcagagctgtacaggagatcatgcaggaaaagtctttt
ggagcagctggtgaaacagttgttgtagaagagtttctggaaggggaagaagtgtcctgc
ctgtgcttcactgacgggaagacggtggccgcaatgcccccagcacaagaccataagcga
ttgctggatggagaccagggccccaacaccgggggaatgggagcctactgcccagcacct
caggtttctaaggacttgttagtaaaaattaaaaacactattcttcagagaacagtagac
ggcatgcagcaggaaggtgcgccatacacaggaattctttatgctggtataatgctgacc
aaagatggcccaaaagttttggagtttaattgccgttttggtgatccagaatgccaagtc
atcctcccgcttcttaaaagtgacctttatgaagtgattcagtccaccttcgatggcctg
ctgagcacgtctctgcctgtttggctagaaaaccacagcgctgtaactgtcgtcatggcg
agtgcagggtaccctggagcctacaccaagggggtggagattacagggtttcctgaggcc
caagctttaggactacaggtattccatgcaggcactgctcttaaagatggcaaagtggtg
accagcgggggcagagtccttgcagtaacagccgtccaggaaaatctcctgtcagccctt
gaggaggccaggaaaggactcgctgctctaaagtttgagggagcagtttatagaaaggac
attggtttccatgctgtggccttcctccagcagcccaggggcctgacttacaaggactcc
ggagtagatattgcagctggaaatatgctggttaagaaaattcagcctttagcaaaagcc
acctccagaccaggctgcagtgttgaccttgggggctttgctggtctttttgatttgaaa
gcagctggttttaaagaccctcttctggcctctggaacagacggtgtgggaactaaactg
aagatcgcccagctgtgcaataagcatgattccattggtcaggatctggttgcgatgtgt
gtgaacgacatccttgcacaaggagcagagcccctcttcttccttgattactttgcctgt
ggaaaacttgacctcagtacaacggaagctgtcgttgctggaattgctgcagcttgtcga
caggctgggtgtgctctcctgggtggggagacagcagagatgcccgacatgtaccctcct
ggagagtatgatcttgctgggtttgctgttggtgctatggagagacaccagaagctccct
cagctagaaaggatcgctgaaggggatgctgttattggagtagcttcatctggtcttcac
agcaatgggtttagccttgtgaggaaaatcgtggagaggtcttcactccagtactcctcc
ccagcacctggtgcttgtggaggtcagaccttaggggatttacttctaactccaaccagg
atctacagccattcactgttgcctatcatacgttcaggacgtgtcaaagcttttgctcat
attactggaggcggattgctggaaaacatccccagagtcctccctcagaagtttggagta
gatttagatgcctgcacctggagggtccccaaggtcttctcatggctacagcaggaagga
cagctctctgaggaagaaatggccaggacattcaactgtggggttggagctgccctggtg
gtgtcaaaggaccagacagagcagattctatatgacattcggcagcaccaggaagaagcc
tgggtgataggcagtgtcgttgcacgtcctgaagattcccctcgtgtcagagttaagaat
ttgattgaaaccatacaaacaaatgagtcagtggtggcaaatggcttcctgagaagcaat
ttccctgtccaacaaaagaaggcaagagtggctgtcttaatatctggaacagggtcaaac
ctccaggcgctcatagacagcacccgagatcctaagagctcctcacacattgttctcgtc
atctccaacaaagctgccgtagccggcttagaccgagcagaacaagctggtattcctacc
agggtaattaatcacaaattatataaaaaccgtgttgagtttgacaacgcaattgactgc
gtcctggaagagttctctgtagacattgtctgtctcgcaggattcatgaggattctctct
ggtccctttgtcagaaaatgggatgggaaaatgctcaacatccacccatccctgctccct
tcttttaagggttcaaatgctcacgagcaagttctggaagctggagtcacaattactggg
tgtaccgtacactttgtagctgaagatgtagatgctggacaaatcatcctgcaggaagct
gtccctgtgcagaggagtgacactgttgcaacactgtctgaacgagtcaaagtagcagaa
cacaagatctttcctgctgctctccagctggtggccagcgggactgtgcagctgcgagaa
gatggcaggatccactgggccagtgagctatga
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