Mastomys coucha (southern multimammate mouse): 116089915
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Entry
116089915 CDS
T07224
Symbol
Setx
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
mcoc
Mastomys coucha (southern multimammate mouse)
Pathway
mcoc05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
mcoc00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
116089915 (Setx)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
mcoc03021
]
116089915 (Setx)
Enzymes [BR:
mcoc01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
116089915 (Setx)
5.6.2.5 RNA 5'-3' helicase
116089915 (Setx)
Transcription machinery [BR:
mcoc03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
116089915 (Setx)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
AAA_30
UvrD-helicase
AAA_22
ResIII
Helicase_RecD
AAA_16
nSTAND3
Motif
Other DBs
NCBI-GeneID:
116089915
NCBI-ProteinID:
XP_031225424
LinkDB
All DBs
Position
Unknown
AA seq
2725 aa
AA seq
DB search
MSTCCWCTPGGSSTIDVLKCYASSTGPSEFQTADEDLCYCLECVAEYHRARDEVPFLHEV
LWKLETFRLISHFEKSMKGEAEDDDDLYIVDNNGEEQLFDCSGQDFENKLRVPLFEILKY
PYLLLHERVNELCVEALCRMEQNNCSFQVFDKYPGIYLFLVHPNEMVRRWAILTARTLGK
VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPAHLYDTTNYKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQSDDDSMDPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNESYNREIQNIRNSSLRTKLEPEPHFDDMVTCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLANVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLYSEVKDVLNQTDAVCDKVTEFFILILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFVRSCEKSPGSTPRGPAIMSSLALHSVPSNSVQLACVQLIR
GLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTGQETHELQMCLKQIIRNIKFKMP
QYSTFGDPTSTFKTPPSFKEESEQIDKKPKKDIYCLENCSPISSKEPMKADSHRVFIKAN
TTEEESFKQHYIDLNEEEPLPAELCSKQKSEALFSESAQEQVKISTEKSGKENSSYTPPN
STSRSGPDWGCDRGVIISTHSLTDSSSGFMEKVCTSKDDVPLKDSTVDKTSKPSFKVQKD
EICAKDGTVGKTSKPNFKVQKDEICAKLSHVIKKQHRKSTLVNNIINLEETTAMSDLENC
SGTGRGALKKDSTEHVSSDPVLDDEREEQKSQNSSLFKKEIKSEELDNSSDDEDKLQIQE
GHADNDLVSFTEVADTLVKKTPCEGPAKVVRSRDKEMRANTVVTSNLVEGQVPHDNSKPL
VADRQIDLCNITLISQTTVIQFPSGLSKQDSFQLQKDDKRYLTANQNSAATSHGQIIVIS
DSDEENEDDENEDERSCNEENIKQTKEYMEKECSEQHGLEKKLEKEETTCVVEFEDSESQ
VFEFESSSEVFSVWQDHKIDSKTSLQEEQKSRITHAADSTNNNLGCGVDSVSEEVRNKEE
GVKEHAEPHSSVAAEELCKTGVRKRKRKRCDKVTAEDPQRPSSSVGTEQSVDHRDLTGSD
LKSADMEMAVPSSSVERDSTVLQKSTKSRTHSKPVRKVPAAKATKKTHSDTRRGQNKSSC
YISCRTSPAIVPPKKFRPCPEPTSTVEKLGLKKAPRKAFELSQRSLECIVQLRDHGKTVG
VVDAPKKTKLISPQTLSIKNNKKLLTSQDLQFQRLMRSRSHQKRDFDYKNTDTVRAVSRI
VQGSDVLAADSDEPDNHRGSEPLAISNEKQLAKCVLSKPEVAEASSDSWVTGITCLVNQC
ESRVLSGGVPTDVVMVSASEDPVGGGALTVQVGEVAAVKATEPESSSDTDDDDNLFLTQH
DPQDMDLCSQLENNKTIIVAHKDTVQREDSLGRPQSESLSITKCKYKDCVETIKNQGEYC
PRHTAAKAADDSLFRKPGLPLSVARPMRPTTTKIFSSSSASRTANLSKSLESTTLQSALK
SKSSGAQPNLKVIPPSSMSSQKPVAEVKSLCNIFHFQTPSSSNKQRNKLTFSENRPTSAS
SPVNILLPSQSIFDTFIKEVLKWKYQMFLNFDKCGAPTSLCQSISRPVPVRFQDCTEYFN
VFLPLIILNAFETMAQEWLSSPNKENFYQLHLRKFPADYKKYWEFLIYLEESELAKQLHP
KENDLVFLVPEKKYMDRHDMQDYNHYYCGYVHKFRRTSVMRSGKAECSLCIQTQNNLPAS
VKELTKCIVISSLVTTQRKLKAMSLLSSRNQLARAILNPNPMDFCTKDLLTTTSERIVSA
DLNEAKKIAYLKDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL
LTESQRKGHSDENFNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD
INLVRLGPEKSINTEVLKFSLDSQVNHRMKKDLPSHIQEMLRRKEILDAELDDLSRQRAL
CRGGREIQRQELDEHIVIVSKERQELASKIKEVQGRPQRAQNTIILESHVICCTLSTSGG
LLLESAFRGQGGVPFSCVIVDEAGQSCEVETLSPLIHRCNKLILVGDPKQLPPTVISMKA
QEYGYDQSMMARFCKLLEENVEQNMIGRLPVLQLTIQYRMHPDICLFPSNYVYNKNLKTN
RLTESIRCSSDWPFQPYLVFDVGDGSEQRDNDSYINVQEIKLVMELIKLIKEKRKDISFR
NIGIITHYKAQKTMIQKDLEKEFDKKGLLQPILMGESRQQDSEVSKQQQKSSECMHASDE
LGSSTVTQSGISSLENGATHTGPAEVDTVDAFQGRQKDCIIVTCVRASAVQGSIGFLASL
QRLNVTITRAKYSLFILGHLRTLMENQHWYELIQDAQKRGAIIKTCDPNYRHDAMKILKL
KPVLQRSLTHPPATAPEAPRPQGGLPSNRLDSGLATTSFAASLYHTPSDTVTSKEPERPL
LQDRLRDPRLLRRLDAEAKGASLKDPQPVSPQLPGVVHLLGGPGFPVVFQDPGFVVPPST
AIVAPLGSHRSPMQAEPPPAHPAAAASTSKRKYSDPDVGLSYRREPRAFSGEHGRHGSVS
HHMLRSTDRDRRRLDDSNAKRRRFL
NT seq
8178 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgctgttggtgcactccaggtggctcttccaccattgatgtcctaaagtgc
tatgcatctagcactggaccaagtgaatttcaaacagctgatgaagacctctgctactgc
ttagagtgtgtggctgagtaccacagagccagagatgaggtgccattcttgcatgaggtt
ttatggaagctagaaaccttccgcctcataagtcactttgagaagtccatgaagggagaa
gctgaagatgatgatgatttatatatagtagacaacaatggagaggaacagctgtttgac
tgtagtggccaagattttgaaaataagcttcgagttccactttttgaaatactgaagtac
ccttacttgcttctgcatgagcgtgttaatgaactgtgtgtggaagcgctttgtcgaatg
gaacaaaacaattgctcctttcaggtttttgacaaatatccaggcatctatttgtttttg
gttcatcccaatgaaatggttcggcgatgggctattctgactgcaagaaccctggggaag
gtggacagagatgactattatgacttacaggaagttttaacttgccttttcaaagtcatt
gagctggggcttttggaaagtccagacatttacacatcttctgtgcttgagaaaggcaaa
ctgatccttttgcctgcacacttgtatgatacaaccaactacaaaaactattggctaggt
atttgcatgttgttgactattcttgaggagcaagccatggattcactgttgctgggctca
gacaaacaaaatgattttatgcaatcaattcttcacaccatggagaggcaatcggatgat
gacagcatggatcctttctggccagcattacactgtttcatggtgattcttgatcgcctt
ggttctaaggtgtggggtcaacttattgatcctatagaagcatttcaaaccatcattaac
aatgagagctacaacagagagatccagaatatacggaacagctccttaaggaccaagtta
gagccggagccacattttgatgatatggtgacgtgcagccagattgtttataactataat
cctgaaaagaccaaaaaggattctgggtggagatcagccatttgtccagattattgtcca
aacatgtatgaagaaatggaaacattagccaatgtacttcagtcagatattggtcaagat
atgcgtgttcataacagcacctttctgtggttcataccttttgttcagtcactcatggat
cttaaggatttgggtgtggcttacatagtagaagttattcatcatctatactcagaagtc
aaagatgtactcaaccaaacagatgctgtgtgtgacaaagtcactgaattttttattctg
attttagtatcagtgattgagctgcatagaaataaaaaatgtttgcatcttctgtgggtg
agttctcagcagtgggtagaagctgttgtgaagtgtgccaagcttcctaccactgcattt
gtacggagttgtgagaagtcacctggaagtacccctagaggaccagcaataatgtcatct
ttggcgttgcattcagtgccatctaactctgtccagcttgcttgtgtacagttgattagg
ggcctcctcaaagaaggttatcagcttggtcagcaaacactttgtaagcggttctgggat
aagcttaatttattccttcgaggaaatttgtctcttggttggcaattgactggtcaagaa
acccatgaattgcaaatgtgtttgaaacaaataattagaaacataaaattcaaaatgccc
caatatagcacttttggggatccaacttctacattcaaaacccctccatcttttaaagaa
gaaagcgaacaaatagacaagaagcctaaaaaagacatttattgcttagaaaattgcagc
ccaatatcttctaaagagccaatgaaagctgacagccatcgagtatttattaaagcaaat
actacagaagaggagtccttcaagcagcattacattgatttgaatgaagaagagcctctt
ccagctgagttgtgctcgaagcagaaaagtgaggctcttttttctgaaagtgctcaagag
caagttaaaataagcacagagaagtctggaaaagaaaactcttcatatacaccaccaaat
agtacttcaagaagtggtccggattggggatgtgacagaggagtgataatatcaacacat
tcattgactgattctagcagtggttttatggaaaaggtatgtacatcaaaagatgatgtc
ccattaaaggatagcactgttgataaaacttcaaaaccaagtttcaaagtacagaaagat
gaaatttgtgcaaaggatggcactgttggtaaaacttcaaaaccaaatttcaaagtacag
aaagatgaaatttgtgcaaagttatcacatgtcataaagaagcaacacaggaaaagtact
ttggtcaataacattatcaatctagaggaaactacagctatgtctgaccttgagaactgt
tcaggaacaggtagaggagctctaaagaaagatagcactgaacatgtgtcttcagaccct
gttctagacgatgagcgtgaagagcaaaaatctcaaaacagttcattgttcaagaaagag
ataaaaagtgaggagttggataatagttctgatgatgaagacaagcttcaaatccaggaa
ggccatgctgacaatgacttggtatcatttacagaagttgctgatacactggtgaagaaa
actccatgtgagggtcctgcaaaggtggttagatcacgagataaggaaatgagggcgaat
acagtggtgacttctaacttggtagaaggacaggtgcctcatgataatagcaagcctttg
gttgcagatcgtcaaatagacctctgtaacataactttaatatctcaaaccactgttatt
caatttccatcaggtttaagtaaacaggattcatttcagctacaaaaggatgataaaaga
tatctgacagctaaccaaaacagtgctgccacctcccatggacaaattattgttatttca
gattctgacgaagaaaatgaagatgatgaaaatgaagatgagagaagttgtaatgaggaa
aatatcaaacagaccaaagaatacatggagaaagaatgttcagagcagcatggtttggaa
aagaagcttgaaaaagaagaaacaacatgtgttgtagaatttgaagactctgaatctcag
gtttttgagtttgaaagttcatctgaagtcttttcagtttggcaagatcataaaatagac
agcaaaacttcacttcaggaggaacaaaagagccgtataactcatgcagctgatagtacg
aacaataacttgggttgtggtgtagactctgtttctgaagaggttagaaacaaagaagag
ggtgttaaagagcatgcagaaccacacagtagtgttgctgctgaggagttgtgtaaaact
ggagtaagaaaacgtaagaggaaacgatgtgacaaagtgacagctgaagatcctcagagg
ccttcctcttctgttggaactgaacagtcggttgatcacagagatcttactggaagtgat
ttaaagagtgcagacatggagatggcagttcccagttcaagtgttgagagagattctaca
gttttacagaagtctacaaagtctcgtactcactcaaaacctgttaggaaagttccagct
gctaaggctactaagaaaacacattcagacaccagaagaggacagaataagagttcatgt
tacataagttgtagaacttctcctgctattgtgccaccaaagaagtttcgtccgtgtcca
gagccaacttcaacagttgaaaaacttggtctgaaaaaagctcctcggaaggcatttgag
ttgtcccagaggtctctggagtgcatagtccaattacgtgaccatggcaagactgttgga
gttgttgatgcccccaaaaaaactaaattaatttctcctcagactctttctatcaaaaat
aataagaagcttctgacaagccaggatcttcaatttcaaaggctcatgagatccagatca
catcaaaaacgagactttgattacaaaaatactgatactgtaagagcagtgtcacgcata
gtacagggttcagatgtacttgcagcagactctgatgagccagataatcatagagggagc
gagccacttgctatcagtaatgaaaaacaattagcaaaatgtgtgctttccaaaccagaa
gtagcagaagcctcttcagattcttgggtgacaggtataacttgtcttgtgaaccagtgt
gagtctagagtgttaagtggaggagtgccaacagatgtagtgatggtctctgcttcagag
gaccctgtgggtggaggtgctctcacagtgcaagttggggaggtggcagctgtgaaagcc
acagagccagagtccagtagtgatacagatgatgatgacaatttatttctaacacaacat
gatcctcaagatatggatctgtgctcacagttggaaaataataaaaccattatcgtggct
cataaagatacagttcagagagaagattctttaggtcggcctcagtcagaatctttgagt
attacaaagtgtaaatacaaagactgtgttgaaaccataaaaaaccagggtgaatactgc
ccaagacacactgcagctaaagcagcagatgacagcctgttccgtaagcctggcttgcct
ctttctgtagccaggcctatgcgacccactactaccaaaatatttagctcaagcagcgct
tcacgaacagccaatctttccaagtctttggaaagtaccacacttcagtcggcactaaaa
agtaagtcaagtggagcacagcctaatttgaaagtgataccaccctcttccatgagttct
cagaagccagtggctgaggtgaaaagtctatgcaatatttttcattttcagactccaagc
agttccaacaaacagagaaacaagcttacatttagtgagaacaggcccacgtcagcttct
tctccagtgaacattctcttgccatcgcagtctatctttgataccttcattaaagaggtc
ttaaaatggaaataccaaatgtttttgaactttgataagtgtggtgctccaacaagtctc
tgccagtctatctcaagacctgtgcctgtccgatttcaagattgtacagaatattttaat
gtttttctacctttgattatattgaatgcttttgaaacaatggcacaggaatggttgagc
tctccaaataaagagaatttctatcagttgcatttacgaaaatttccggctgactataaa
aaatactgggagtttctgatttacttggaggaatctgaactagctaaacagcttcaccca
aaggaaaatgatctggtgttcttggttcctgagaagaagtatatggacaggcatgatatg
caagattacaatcactattactgtggctatgtgcataagtttcgtcgtacttcagtcatg
cgcagtgggaaagctgagtgttcattatgcatccagacacaaaataacttgccagccagt
gtaaaagaacttacaaaatgtattgtaatcagttctctggtaactacacagaggaaattg
aaagccatgtctctgttgagtagtcggaaccagttggccagagctattttaaatccaaac
cccatggacttctgtaccaaagatctactaactacaacgtctgaaagaattgtgagtgct
gatttgaatgaagccaagaaaattgcctacttaaaagactttaatgaagaccagaagaaa
gccatagaaactgcatatgccatggtgaagcactcaccatccgttgccaaaatctgtctg
attcatggaccacctggaacaggaaaatcaaaaactattgttggtctcttgtaccgctta
ttgacagagagccagaggaagggccattcagatgaaaatttcaatgccaaaatcaaacaa
aatcgagtcctcgtgtgtgcgccttccaatgcagcggttgatgaacttatgaaaaaaatt
atcctcgagttcaaagaaaaatgtaaagacaagaagaatcctttgggaaactgtggagat
ataaacttagtacgactgggtccagaaaagtctattaatacagaggtcctaaaattcagt
ttggacagccaagtcaaccatagaatgaaaaaagacttgccttctcatattcaagaaatg
cttagaagaaaagaaattctagatgctgaacttgatgatctttctcgtcagcgagctctg
tgtcgaggtgggcgggagatacagaggcaagaattagatgaacacattgtcatagtttca
aaagaaaggcaagaacttgcttcaaaaattaaagaggttcaaggacgcccacagagagca
cagaataccatcatcttggagtcccatgtcatttgctgcacattgagcactagtggtggt
ttattgcttgagtctgcttttcgaggtcaagggggtgtccccttcagttgtgtcattgta
gatgaggctgggcagtcttgtgaagttgagacactttctccactcatccaccgctgcaat
aaacttatcctagtaggagaccccaaacagctccctcccacagtcatctctatgaaagca
caggagtatggctatgaccagtcgatgatggcacgattctgcaagctgctggaagagaat
gtggagcagaacatgattggcaggctgccggtattacagcttaccattcagtacaggatg
catccagacatatgtctcttcccttcgaattatgtttataacaagaacctgaagacaaat
agattgaccgaatccattcgatgttcatcagattggccatttcagccctacctcgtgttt
gatgttggagatggttcagaacaacgggataatgactcatacataaatgttcaagaaata
aagttggtgatggaactaattaaacttattaaagagaaaagaaaagatatttccttccga
aatattggcataataacccattacaaggctcagaagacgatgatccagaaggatttggag
aaagaatttgataagaaaggtttattacagcccatcttgatgggagaatcaaggcagcaa
gactctgaagtatccaagcagcagcagaagagcagtgaatgtatgcatgctagtgatgag
ctcggttcctccactgttacacagtccgggatctccagcctagagaatggtgccacccac
actggacctgcagaagtggatacggtagatgccttccaaggccggcagaaagattgtatc
atcgttacctgtgtcagggcaagtgctgtgcaaggctcaataggattcctggcaagtttg
cagagattgaatgtcaccattacacgagccaagtacagcctctttatccttggacatttg
aggactctgatggaaaaccagcattggtatgaactaattcaggatgctcagaagcgtggt
gccattattaagacctgtgacccaaactatagacacgatgcaatgaaaattttaaaactg
aagcctgtgctacagaggagtctgacccatcccccagccactgcaccagaggcacccaga
cctcagggtggcttgcccagcaacaggctggacagtggacttgctacaacatcttttgct
gcttctttgtatcacacaccctctgatactgtcacttcaaaggaacctgaaaggccactt
cttcaagaccgacttcgagatccacgactacttaggagacttgatgctgaagccaaagga
gcatccctgaaagacccacagcctgtgagcccccagctccctggggtagttcatctcttg
ggagggcctggctttcctgtggttttccaggacccaggttttgttgtaccaccatccact
gccatcgttgctcctctgggcagccacaggtcacctatgcaggctgagccaccacctgct
caccctgctgctgccgcctccacaagtaagaggaagtacagtgacccagatgttgggctc
agctacagaagagagcccagggccttcagtggagagcacgggagacatggctctgtgagt
catcacatgctgagaagcactgaccgggacaggaggaggctggatgacagcaatgccaag
aggagacggtttctatag
DBGET
integrated database retrieval system
