KEGG   Mastomys coucha (southern multimammate mouse): 116091289
Entry
116091289         CDS       T07224                                 
Symbol
Src
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X1
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
mcoc  Mastomys coucha (southern multimammate mouse)
Pathway
mcoc01521  EGFR tyrosine kinase inhibitor resistance
mcoc01522  Endocrine resistance
mcoc04012  ErbB signaling pathway
mcoc04015  Rap1 signaling pathway
mcoc04062  Chemokine signaling pathway
mcoc04081  Hormone signaling
mcoc04137  Mitophagy - animal
mcoc04144  Endocytosis
mcoc04360  Axon guidance
mcoc04370  VEGF signaling pathway
mcoc04510  Focal adhesion
mcoc04520  Adherens junction
mcoc04530  Tight junction
mcoc04540  Gap junction
mcoc04611  Platelet activation
mcoc04613  Neutrophil extracellular trap formation
mcoc04625  C-type lectin receptor signaling pathway
mcoc04727  GABAergic synapse
mcoc04750  Inflammatory mediator regulation of TRP channels
mcoc04810  Regulation of actin cytoskeleton
mcoc04912  GnRH signaling pathway
mcoc04915  Estrogen signaling pathway
mcoc04917  Prolactin signaling pathway
mcoc04919  Thyroid hormone signaling pathway
mcoc04921  Oxytocin signaling pathway
mcoc04926  Relaxin signaling pathway
mcoc05100  Bacterial invasion of epithelial cells
mcoc05135  Yersinia infection
mcoc05152  Tuberculosis
mcoc05161  Hepatitis B
mcoc05163  Human cytomegalovirus infection
mcoc05167  Kaposi sarcoma-associated herpesvirus infection
mcoc05168  Herpes simplex virus 1 infection
mcoc05203  Viral carcinogenesis
mcoc05205  Proteoglycans in cancer
mcoc05207  Chemical carcinogenesis - receptor activation
mcoc05208  Chemical carcinogenesis - reactive oxygen species
mcoc05219  Bladder cancer
mcoc05417  Lipid and atherosclerosis
mcoc05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mcoc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    116091289 (Src)
   04015 Rap1 signaling pathway
    116091289 (Src)
   04370 VEGF signaling pathway
    116091289 (Src)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    116091289 (Src)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    116091289 (Src)
   04137 Mitophagy - animal
    116091289 (Src)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    116091289 (Src)
   04520 Adherens junction
    116091289 (Src)
   04530 Tight junction
    116091289 (Src)
   04540 Gap junction
    116091289 (Src)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    116091289 (Src)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    116091289 (Src)
   04613 Neutrophil extracellular trap formation
    116091289 (Src)
   04625 C-type lectin receptor signaling pathway
    116091289 (Src)
   04062 Chemokine signaling pathway
    116091289 (Src)
  09152 Endocrine system
   04912 GnRH signaling pathway
    116091289 (Src)
   04915 Estrogen signaling pathway
    116091289 (Src)
   04917 Prolactin signaling pathway
    116091289 (Src)
   04921 Oxytocin signaling pathway
    116091289 (Src)
   04926 Relaxin signaling pathway
    116091289 (Src)
   04919 Thyroid hormone signaling pathway
    116091289 (Src)
  09156 Nervous system
   04727 GABAergic synapse
    116091289 (Src)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    116091289 (Src)
  09158 Development and regeneration
   04360 Axon guidance
    116091289 (Src)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    116091289 (Src)
   05207 Chemical carcinogenesis - receptor activation
    116091289 (Src)
   05208 Chemical carcinogenesis - reactive oxygen species
    116091289 (Src)
   05203 Viral carcinogenesis
    116091289 (Src)
  09162 Cancer: specific types
   05219 Bladder cancer
    116091289 (Src)
  09172 Infectious disease: viral
   05161 Hepatitis B
    116091289 (Src)
   05168 Herpes simplex virus 1 infection
    116091289 (Src)
   05163 Human cytomegalovirus infection
    116091289 (Src)
   05167 Kaposi sarcoma-associated herpesvirus infection
    116091289 (Src)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    116091289 (Src)
   05152 Tuberculosis
    116091289 (Src)
   05100 Bacterial invasion of epithelial cells
    116091289 (Src)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    116091289 (Src)
   05418 Fluid shear stress and atherosclerosis
    116091289 (Src)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    116091289 (Src)
   01522 Endocrine resistance
    116091289 (Src)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mcoc01001]
    116091289 (Src)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mcoc04131]
    116091289 (Src)
Enzymes [BR:mcoc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     116091289 (Src)
Protein kinases [BR:mcoc01001]
 Non-receptor tyrosine kinases
  SRC family
   116091289 (Src)
Membrane trafficking [BR:mcoc04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    116091289 (Src)
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    116091289 (Src)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    116091289 (Src)
  Macropinocytosis
   Kinases
    116091289 (Src)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH2_1 ABC1 Haspin_kinase
Other DBs
NCBI-GeneID: 116091289
NCBI-ProteinID: XP_031228411
LinkDB
Position
Unknown
AA seq 542 aa
MGSNKSKPKDASQRRRSLEPTENVHGAGGAFPASQTPSKPASADGHRGPSAAFVPPAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKV
DVREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGT
FLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYS
KHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR
VAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLK
GETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLI
EDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREV
LDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGE
NL
NT seq 1629 nt   +upstreamnt  +downstreamnt
atgggcagcaacaagagcaagcccaaggacgccagccagcggcgccgcagcctagagccc
acggagaacgtgcacggggctgggggcgccttcccggcctcacagacaccgagcaagccc
gcctccgccgacggccaccgagggcccagcgccgccttcgtgccccccgcggccgccgag
cccaagctcttcggaggcttcaactcctcggacaccgtcacctccccgcagagggcgggg
cctctggcaggtggggtgaccacctttgtggccctctatgactatgagtcacggacagag
actgacctgtccttcaagaaaggggagcggctgcagattgtcaataacacgaggaaggtg
gatgtcagagagggagactggtggctggcacactcgctgagcacaggacagaccggttac
atccccagcaactatgtggcgccctccgactccatccaggctgaggagtggtactttggc
aagatcactagacgggaatcagagcgtctactgctcaacgctgagaacccgagagggacc
ttcctcgtgagggagagtgagaccacaaaaggtgcctactgcctctccgtatccgacttc
gacaacgccaagggcctaaatgtgaaacattacaagatccggaaactggacagcggcggg
ttctacatcacctcccgcacccagttcaacagcctgcagcagctcgtggcttactactcc
aaacatgctgatggcctctgtcaccgactcactaccgtgtgtcccacatccaagcctcag
acccagggcctggccaaggatgcgtgggagatcccccgggagtccctgcggctggaggtc
aagctgggccagggctgcttcggagaggtgtggatggggacctggaatggtaccacgagg
gttgctatcaaaaccctgaagccaggcaccatgtctccagaggccttcctgcaggaggct
caagtcatgaagaaactgaggcatgagaagctggtgcagctgtatgccgtggtgtcagaa
gaacccatttacattgtgacagagtacatgaacaagggaagcctgctggactttctcaag
ggagaaacggggaaatacttgcggctaccccagctggtggacatgtccgctcagatcgct
tcaggcatggcctatgtggagcggatgaactatgtgcaccgggacctccgagctgccaat
atcctggttggagagaacctggtgtgcaaagtggccgactttgggctggcccggctcata
gaagacaacgaatacacagcccggcaaggtgccaaattccccatcaagtggaccgcccct
gaagctgctctgtacggcaggttcaccattaaatcggatgtgtggtcctttgggatcctg
ctgaccgagctcaccactaagggaagagtgccctatcctgggatggtgaaccgagaggtc
ctggaccaggtggagaggggctaccggatgccttgtccccccgagtgccctgagtctctg
catgacctcatgtgccagtgctggcggaaagagcccgaggagcggcccaccttcgagtac
ctgcaggccttcctggaggactactttacgtccacggagccgcagtaccagcccggggag
aacctatag

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