Mastomys coucha (southern multimammate mouse): 116097543
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Entry
116097543 CDS
T07224
Symbol
Nos3
Name
(RefSeq) nitric oxide synthase, endothelial isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
mcoc
Mastomys coucha (southern multimammate mouse)
Pathway
mcoc00220
Arginine biosynthesis
mcoc00330
Arginine and proline metabolism
mcoc01100
Metabolic pathways
mcoc04020
Calcium signaling pathway
mcoc04022
cGMP-PKG signaling pathway
mcoc04066
HIF-1 signaling pathway
mcoc04071
Sphingolipid signaling pathway
mcoc04151
PI3K-Akt signaling pathway
mcoc04370
VEGF signaling pathway
mcoc04371
Apelin signaling pathway
mcoc04611
Platelet activation
mcoc04915
Estrogen signaling pathway
mcoc04921
Oxytocin signaling pathway
mcoc04926
Relaxin signaling pathway
mcoc04931
Insulin resistance
mcoc04933
AGE-RAGE signaling pathway in diabetic complications
mcoc05415
Diabetic cardiomyopathy
mcoc05417
Lipid and atherosclerosis
mcoc05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mcoc00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
116097543 (Nos3)
00330 Arginine and proline metabolism
116097543 (Nos3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
116097543 (Nos3)
04371 Apelin signaling pathway
116097543 (Nos3)
04066 HIF-1 signaling pathway
116097543 (Nos3)
04020 Calcium signaling pathway
116097543 (Nos3)
04071 Sphingolipid signaling pathway
116097543 (Nos3)
04022 cGMP-PKG signaling pathway
116097543 (Nos3)
04151 PI3K-Akt signaling pathway
116097543 (Nos3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
116097543 (Nos3)
09152 Endocrine system
04915 Estrogen signaling pathway
116097543 (Nos3)
04921 Oxytocin signaling pathway
116097543 (Nos3)
04926 Relaxin signaling pathway
116097543 (Nos3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
116097543 (Nos3)
05418 Fluid shear stress and atherosclerosis
116097543 (Nos3)
05415 Diabetic cardiomyopathy
116097543 (Nos3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
116097543 (Nos3)
04933 AGE-RAGE signaling pathway in diabetic complications
116097543 (Nos3)
Enzymes [BR:
mcoc01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
116097543 (Nos3)
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Gene cluster
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
116097543
NCBI-ProteinID:
XP_031236003
LinkDB
All DBs
Position
Unknown
AA seq
1202 aa
AA seq
DB search
MGNLKSVGQEPGPPCGLGLGLGLGLCGKQGPASPAPEPSQAPAPQSPTRPAPDHSPPLTR
PPDGPRFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQSRPTQGPSPTE
QLLAQARDFINQYYNSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNA
PRCVGRIQWGKLQVFDARDCRTAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGDF
RIWNSQLIRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDELPE
LFTLPPEMVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSSE
IGMRDLCDPHRYNVLEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHH
AATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWK
GSAAKGAGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRL
FRKAFDPRVLCMDEYDVVSLEHEALVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSSP
RPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFC
AFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDAKVAAR
DIFSPKRSWKRQRYRLSTQAESLQLLPGLTHVHRRKMFQATILSVENLQSSKSTRATILV
RLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPPSTEPVAVEQLEKGSPGGPP
PGWVRDPRLPPCTLRQALTYFLDITSPPSPRLLRLLSTLAEESSEQQELEALSQDPRRYE
EWKWFRCPTLLEVLEQFPSVALPAPLILTQLPLLQPRYYSVSSASSIHPGEIHLTVAVLA
YRTQDGLGPLHYGVCSTWMSQLKAGDPVPCFIRGAPSFRLPPDPNLPCILVGPGTGIAPF
RGFWQDRLHDIEIKGLQPAPMTLVFGCRCSQLDHLYRDEVLDAQQRGVFGQVLTAFSRDP
GSPKTYVQDLLRTELAAEVHRVLCLEQGHMFVCGDVTMATSVLQTVQRILATEGGMELDE
AGDVIGILRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWSFDPPGPETP
GS
NT seq
3609 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagtgtgggccaggagcctgggccaccctgtggcctagggctcggg
ctgggcctaggactgtgcggcaagcagggtccagcctctccagcaccggaacctagccag
gcaccagcaccccagtccccaacccgaccagcaccagaccacagccccccgctaacccga
cccccagacggacccaggtttcctcgagtaaagaactgggaagtgggcagcatcacctac
gacaccctcagtgcccaggctcagcaggatgggccctgtaccccaagacgctgcttggga
tccctggtatttccaaggaagttacagagccggcccacccagggcccttcacccactgag
cagctattggctcaagcccgggacttcatcaatcagtactataactccatcaaaaggagt
ggttcccaggctcatgagcagcggcttcaggaagtggaggctgaggtggcagccacaggc
acctaccagctccgggagagtgagctggtgtttggggccaagcaggcctggcgtaatgct
ccccgatgtgtgggccggatccagtggggaaagctgcaggtattcgatgctcgggactgc
aggaccgcacaggaaatgttcacctacatctgtaaccacattaagtatgcaacaaataga
ggcaatcttcgttcagccatcacagtgttcccccagcgctgccctggccggggagacttc
cggatctggaacagccagctgatccgctatgcaggctacaggcagcaggatggctcggtg
cgaggggaccctgccaacgtggagatcactgagctctgtatccaacatggctggacccca
ggaaatggtcgctttgatgtgctgcccctgttactccaggctcctgatgaactcccagaa
ctcttcactctgcccccagagatggtcctcgaggtgcctctggagcaccccacgctagag
tggtttgctgcccttggcctgcgctggtatgccctcccagctgtgtccaacatgctgcta
gaaatcgggggtctggagtttcctgctgcccctttcagtggctggtacatgagttcagag
attggcatgagggacctgtgtgaccctcaccgctacaacgtacttgaggatgtggctgtc
tgcatggatctagacaccaggacaacctcatccctgtggaaagacaaggcagcggtggaa
attaatgtggctgtactgcacagttaccagctggccaaagtgaccatagtggaccaccac
gccgccacagcctccttcatgaagcacctggaaaatgagcagaaggccagagggggctgc
cctgccgattgggcctggatcgtgccccccatctcaggcagcctcactcctgtcttccat
caagagatggtcaactatttcctgtcccctgccttccgctaccagccagacccctggaag
ggaagtgcggcaaagggcgcaggcatcaccaggaagaagacctttaaggaagtagccaat
gcagtgaagatctctgcctcactcatgggcacggtgatggcgaagcgtgtgaaggcaacc
atcctgtatggctctgagactggccgggcccagagctacgcacagcagctggggaggctc
ttccggaaggcgtttgatccccgggtcctgtgcatggatgagtatgatgtggtatctcta
gagcacgaggcactggtgttggtggtgaccagcacatttggcaatggggatcccccggag
aatggagagagctttgcagcagcactgatggaaatgtcaggcccctacaacagctccccg
aggcctgaacagcacaagagctacaaaatccgattcaacagtgtctcctgctcagaccca
ctggtatcctcctggaggcgcaagaggaaggagtctagtaacacagacagtgcaggggcc
ctgggcaccctcaggttctgtgtgtttgggctgggctcccgagcatacccccacttctgt
gcctttgctcgagcggtggacacaaggctggaggagctgggcggggagcgcctactgcag
ctgggccagggtgatgagctctgtggccaggaggaggctttccgaggctgggcccaggca
gccttccaggctgcctgtgaaaccttctgtgtgggagaagatgccaaagttgctgcccga
gatatcttcagccccaaacgcagctggaagcgccagaggtaccggctgagtactcaggct
gagagcctgcagttactaccagggctgactcacgtgcacaggcggaagatgtttcaggct
acaatcctctctgtggaaaacctacagagcagcaaatccacccgagccacaatcctggtg
cgtttggacactggaggccaggagggactgcagtatcagccaggggaccacataggtgtg
tgcccacccaaccggcccggcctagtggaggcactgctgagccgagtggaggaccctcca
ccatccacagagcctgtggctgtggaacagctggagaaaggcagccctggtggccctccc
cctggctgggtacgggacccccggctacccccatgtacgctgcgccaggctctcacctac
ttcctggacatcacttccccacccagccctcgcctccttcgactactcagcaccctggca
gaagagtccagtgaacagcaggagctagaggctctcagccaggacccccggcgctacgaa
gagtggaagtggttccgctgccccacactgctagaggtgctggagcagtttccatcagtg
gcactgcctgccccgctgatcctcacccagctgcccctgctccagccccggtactactct
gtcagctcagcatccagcatccacccaggagagatccacctcactgtagctgtgctggca
tacagaacccaggatgggctgggccctctacactacggtgtctgttccacatggatgagc
caactcaaggcaggagacccagtgccctgcttcatcaggggggctccctccttccggctg
ccacctgatcctaacttgccctgcatcctggtgggcccaggaactggtattgcacccttc
cggggattctggcaggaccgattacatgacattgaaatcaaagggctacagcctgccccc
atgactttggtgtttggctgccgatgctcccaacttgaccatctctaccgggacgaagta
ctggatgcccagcagcgtggggtgtttggacaagtcctcaccgccttttccagggatcct
ggcagccccaagacctatgtgcaagacctcctgaggacagagctggccgcggaggttcac
cgcgtgctgtgcctcgagcaaggacacatgtttgtctgcggcgacgtcactatggcaacc
agcgtcctgcaaaccgtgcagcgaattctggcaacagagggcggcatggagctggatgaa
gctggtgacgtcatcggcatactgcgggatcagcaacgctaccacgaggacattttcgga
cttacattacgcacccaggaggtgacaagccgcatccgcacccagagcttttctttgcag
gagcggcagctgaggggtgcagtgccctggtcctttgacccgcctggcccagaaacccct
ggttcctga
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integrated database retrieval system
