KEGG   Mastomys coucha (southern multimammate mouse): 116101889
Entry
116101889         CDS       T07224                                 
Symbol
Akt2
Name
(RefSeq) RAC-beta serine/threonine-protein kinase
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
mcoc  Mastomys coucha (southern multimammate mouse)
Pathway
mcoc01521  EGFR tyrosine kinase inhibitor resistance
mcoc01522  Endocrine resistance
mcoc01524  Platinum drug resistance
mcoc04010  MAPK signaling pathway
mcoc04012  ErbB signaling pathway
mcoc04014  Ras signaling pathway
mcoc04015  Rap1 signaling pathway
mcoc04022  cGMP-PKG signaling pathway
mcoc04024  cAMP signaling pathway
mcoc04062  Chemokine signaling pathway
mcoc04066  HIF-1 signaling pathway
mcoc04068  FoxO signaling pathway
mcoc04071  Sphingolipid signaling pathway
mcoc04072  Phospholipase D signaling pathway
mcoc04140  Autophagy - animal
mcoc04150  mTOR signaling pathway
mcoc04151  PI3K-Akt signaling pathway
mcoc04152  AMPK signaling pathway
mcoc04210  Apoptosis
mcoc04211  Longevity regulating pathway
mcoc04213  Longevity regulating pathway - multiple species
mcoc04218  Cellular senescence
mcoc04261  Adrenergic signaling in cardiomyocytes
mcoc04370  VEGF signaling pathway
mcoc04371  Apelin signaling pathway
mcoc04380  Osteoclast differentiation
mcoc04510  Focal adhesion
mcoc04550  Signaling pathways regulating pluripotency of stem cells
mcoc04611  Platelet activation
mcoc04613  Neutrophil extracellular trap formation
mcoc04620  Toll-like receptor signaling pathway
mcoc04625  C-type lectin receptor signaling pathway
mcoc04630  JAK-STAT signaling pathway
mcoc04660  T cell receptor signaling pathway
mcoc04662  B cell receptor signaling pathway
mcoc04664  Fc epsilon RI signaling pathway
mcoc04666  Fc gamma R-mediated phagocytosis
mcoc04668  TNF signaling pathway
mcoc04722  Neurotrophin signaling pathway
mcoc04725  Cholinergic synapse
mcoc04728  Dopaminergic synapse
mcoc04810  Regulation of actin cytoskeleton
mcoc04910  Insulin signaling pathway
mcoc04914  Progesterone-mediated oocyte maturation
mcoc04915  Estrogen signaling pathway
mcoc04917  Prolactin signaling pathway
mcoc04919  Thyroid hormone signaling pathway
mcoc04920  Adipocytokine signaling pathway
mcoc04922  Glucagon signaling pathway
mcoc04923  Regulation of lipolysis in adipocytes
mcoc04926  Relaxin signaling pathway
mcoc04929  GnRH secretion
mcoc04931  Insulin resistance
mcoc04932  Non-alcoholic fatty liver disease
mcoc04933  AGE-RAGE signaling pathway in diabetic complications
mcoc04935  Growth hormone synthesis, secretion and action
mcoc04936  Alcoholic liver disease
mcoc04973  Carbohydrate digestion and absorption
mcoc05010  Alzheimer disease
mcoc05017  Spinocerebellar ataxia
mcoc05132  Salmonella infection
mcoc05135  Yersinia infection
mcoc05142  Chagas disease
mcoc05145  Toxoplasmosis
mcoc05152  Tuberculosis
mcoc05160  Hepatitis C
mcoc05161  Hepatitis B
mcoc05162  Measles
mcoc05163  Human cytomegalovirus infection
mcoc05164  Influenza A
mcoc05165  Human papillomavirus infection
mcoc05166  Human T-cell leukemia virus 1 infection
mcoc05167  Kaposi sarcoma-associated herpesvirus infection
mcoc05168  Herpes simplex virus 1 infection
mcoc05169  Epstein-Barr virus infection
mcoc05170  Human immunodeficiency virus 1 infection
mcoc05200  Pathways in cancer
mcoc05205  Proteoglycans in cancer
mcoc05207  Chemical carcinogenesis - receptor activation
mcoc05208  Chemical carcinogenesis - reactive oxygen species
mcoc05210  Colorectal cancer
mcoc05211  Renal cell carcinoma
mcoc05212  Pancreatic cancer
mcoc05213  Endometrial cancer
mcoc05214  Glioma
mcoc05215  Prostate cancer
mcoc05218  Melanoma
mcoc05220  Chronic myeloid leukemia
mcoc05221  Acute myeloid leukemia
mcoc05222  Small cell lung cancer
mcoc05223  Non-small cell lung cancer
mcoc05224  Breast cancer
mcoc05225  Hepatocellular carcinoma
mcoc05226  Gastric cancer
mcoc05230  Central carbon metabolism in cancer
mcoc05231  Choline metabolism in cancer
mcoc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mcoc05415  Diabetic cardiomyopathy
mcoc05417  Lipid and atherosclerosis
mcoc05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mcoc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    116101889 (Akt2)
   04012 ErbB signaling pathway
    116101889 (Akt2)
   04014 Ras signaling pathway
    116101889 (Akt2)
   04015 Rap1 signaling pathway
    116101889 (Akt2)
   04370 VEGF signaling pathway
    116101889 (Akt2)
   04371 Apelin signaling pathway
    116101889 (Akt2)
   04630 JAK-STAT signaling pathway
    116101889 (Akt2)
   04668 TNF signaling pathway
    116101889 (Akt2)
   04066 HIF-1 signaling pathway
    116101889 (Akt2)
   04068 FoxO signaling pathway
    116101889 (Akt2)
   04072 Phospholipase D signaling pathway
    116101889 (Akt2)
   04071 Sphingolipid signaling pathway
    116101889 (Akt2)
   04024 cAMP signaling pathway
    116101889 (Akt2)
   04022 cGMP-PKG signaling pathway
    116101889 (Akt2)
   04151 PI3K-Akt signaling pathway
    116101889 (Akt2)
   04152 AMPK signaling pathway
    116101889 (Akt2)
   04150 mTOR signaling pathway
    116101889 (Akt2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    116101889 (Akt2)
  09143 Cell growth and death
   04210 Apoptosis
    116101889 (Akt2)
   04218 Cellular senescence
    116101889 (Akt2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    116101889 (Akt2)
   04550 Signaling pathways regulating pluripotency of stem cells
    116101889 (Akt2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    116101889 (Akt2)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    116101889 (Akt2)
   04613 Neutrophil extracellular trap formation
    116101889 (Akt2)
   04620 Toll-like receptor signaling pathway
    116101889 (Akt2)
   04625 C-type lectin receptor signaling pathway
    116101889 (Akt2)
   04660 T cell receptor signaling pathway
    116101889 (Akt2)
   04662 B cell receptor signaling pathway
    116101889 (Akt2)
   04664 Fc epsilon RI signaling pathway
    116101889 (Akt2)
   04666 Fc gamma R-mediated phagocytosis
    116101889 (Akt2)
   04062 Chemokine signaling pathway
    116101889 (Akt2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    116101889 (Akt2)
   04922 Glucagon signaling pathway
    116101889 (Akt2)
   04923 Regulation of lipolysis in adipocytes
    116101889 (Akt2)
   04920 Adipocytokine signaling pathway
    116101889 (Akt2)
   04929 GnRH secretion
    116101889 (Akt2)
   04915 Estrogen signaling pathway
    116101889 (Akt2)
   04914 Progesterone-mediated oocyte maturation
    116101889 (Akt2)
   04917 Prolactin signaling pathway
    116101889 (Akt2)
   04926 Relaxin signaling pathway
    116101889 (Akt2)
   04935 Growth hormone synthesis, secretion and action
    116101889 (Akt2)
   04919 Thyroid hormone signaling pathway
    116101889 (Akt2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    116101889 (Akt2)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    116101889 (Akt2)
  09156 Nervous system
   04725 Cholinergic synapse
    116101889 (Akt2)
   04728 Dopaminergic synapse
    116101889 (Akt2)
   04722 Neurotrophin signaling pathway
    116101889 (Akt2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    116101889 (Akt2)
  09149 Aging
   04211 Longevity regulating pathway
    116101889 (Akt2)
   04213 Longevity regulating pathway - multiple species
    116101889 (Akt2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    116101889 (Akt2)
   05205 Proteoglycans in cancer
    116101889 (Akt2)
   05207 Chemical carcinogenesis - receptor activation
    116101889 (Akt2)
   05208 Chemical carcinogenesis - reactive oxygen species
    116101889 (Akt2)
   05230 Central carbon metabolism in cancer
    116101889 (Akt2)
   05231 Choline metabolism in cancer
    116101889 (Akt2)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    116101889 (Akt2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    116101889 (Akt2)
   05212 Pancreatic cancer
    116101889 (Akt2)
   05225 Hepatocellular carcinoma
    116101889 (Akt2)
   05226 Gastric cancer
    116101889 (Akt2)
   05214 Glioma
    116101889 (Akt2)
   05221 Acute myeloid leukemia
    116101889 (Akt2)
   05220 Chronic myeloid leukemia
    116101889 (Akt2)
   05218 Melanoma
    116101889 (Akt2)
   05211 Renal cell carcinoma
    116101889 (Akt2)
   05215 Prostate cancer
    116101889 (Akt2)
   05213 Endometrial cancer
    116101889 (Akt2)
   05224 Breast cancer
    116101889 (Akt2)
   05222 Small cell lung cancer
    116101889 (Akt2)
   05223 Non-small cell lung cancer
    116101889 (Akt2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    116101889 (Akt2)
   05170 Human immunodeficiency virus 1 infection
    116101889 (Akt2)
   05161 Hepatitis B
    116101889 (Akt2)
   05160 Hepatitis C
    116101889 (Akt2)
   05164 Influenza A
    116101889 (Akt2)
   05162 Measles
    116101889 (Akt2)
   05168 Herpes simplex virus 1 infection
    116101889 (Akt2)
   05163 Human cytomegalovirus infection
    116101889 (Akt2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    116101889 (Akt2)
   05169 Epstein-Barr virus infection
    116101889 (Akt2)
   05165 Human papillomavirus infection
    116101889 (Akt2)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    116101889 (Akt2)
   05135 Yersinia infection
    116101889 (Akt2)
   05152 Tuberculosis
    116101889 (Akt2)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    116101889 (Akt2)
   05142 Chagas disease
    116101889 (Akt2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    116101889 (Akt2)
   05017 Spinocerebellar ataxia
    116101889 (Akt2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    116101889 (Akt2)
   05418 Fluid shear stress and atherosclerosis
    116101889 (Akt2)
   05415 Diabetic cardiomyopathy
    116101889 (Akt2)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    116101889 (Akt2)
   04932 Non-alcoholic fatty liver disease
    116101889 (Akt2)
   04931 Insulin resistance
    116101889 (Akt2)
   04933 AGE-RAGE signaling pathway in diabetic complications
    116101889 (Akt2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    116101889 (Akt2)
   01524 Platinum drug resistance
    116101889 (Akt2)
   01522 Endocrine resistance
    116101889 (Akt2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mcoc01001]
    116101889 (Akt2)
Enzymes [BR:mcoc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     116101889 (Akt2)
Protein kinases [BR:mcoc01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   116101889 (Akt2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PH Kinase-like Pkinase_C PH_20 PH_11 ABC1
Other DBs
NCBI-GeneID: 116101889
NCBI-ProteinID: XP_031241706
LinkDB
Position
Unknown
AA seq 481 aa
MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC
QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRGPGEDAM
DYKCGSPSDSSTSEMMEVAVNKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM
KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH
LSRERVFTEDRARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG
ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE
LILMEEIRFPRTLGPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK
KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGSLELDQRTHFPQFSYSASIR
E
NT seq 1446 nt   +upstreamnt  +downstreamnt
atgaatgaggtatctgtcatcaaagaaggctggctccacaaacgtggtgaatacatcaag
acctggaggccccggtacttccttctgaagagtgatggatctttcattgggtataaggag
agacccgaggcccccgaccagaccttaccccccctgaacaatttctctgtagcagaatgc
cagctgatgaagactgagaggccacgacccaacacctttgtcatacgctgcctgcagtgg
accacagtcattgagaggaccttccatgtagactctccagatgagagggaagaatggatg
cgggctatccagatggttgccaacagtctgaagcaacggggcccaggtgaggatgccatg
gattacaagtgtggctccccaagtgactcttccacatctgagatgatggaggtagctgtc
aacaaggcacgggccaaagtgaccatgaatgacttcgattatctcaaactcctcggcaag
ggcaccttcggcaaagtcattctagttcgagagaaggccactggccgctattatgccatg
aagatcctgcggaaggaggtcatcattgcaaaggatgaagttgcccatacagtcacagag
agccgggtcctgcagaataccaggcacccctttcttacagccctgaagtatgccttccag
acccatgaccgtctgtgctttgtgatggagtatgctaacgggggtgagctctttttccac
ctctctcgggagcgagtcttcacagaggatcgggcgcgcttttatggcgcagagattgta
tcagctctggagtatttgcactcaagagatgtggtgtaccgcgacatcaagctggaaaac
cttatgttggacaaagatggccacatcaagatcactgactttggattgtgcaaagagggc
atcagtgatggggccaccatgaaaaccttctgtggtaccccggagtacttggcgcctgag
gtgctagaggacaatgactacgggcgcgcagtggactggtgggggctgggtgtggtcatg
tatgagatgatgtgtggccgcctgcccttctacaaccaggatcatgagcgcctcttcgag
ctcatcctcatggaggagatccgcttcccacgcacgcttgggccagaggccaagtcccta
ctggctgggctgctgaagaaggaccctaagcagaggctcggcggaggtcccagtgatgca
aaggaggtcatggagcataggttcttcctcagcatcaattggcaggatgtggtacagaaa
aagctcctgccacccttcaaacctcaggtcacttcagaagtggacacaaggtacttcgat
gatgaatttaccgcccagtccatcacaatcacacccccagaccgatatgacagcctgggc
tcgctggaactggaccagcggacgcacttcccccagttctcctactcagccagcatccga
gagtga

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