Mastomys coucha (southern multimammate mouse): 116102373
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Entry
116102373 CDS
T07224
Symbol
Igf1r
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
mcoc
Mastomys coucha (southern multimammate mouse)
Pathway
mcoc01521
EGFR tyrosine kinase inhibitor resistance
mcoc01522
Endocrine resistance
mcoc04010
MAPK signaling pathway
mcoc04014
Ras signaling pathway
mcoc04015
Rap1 signaling pathway
mcoc04066
HIF-1 signaling pathway
mcoc04068
FoxO signaling pathway
mcoc04081
Hormone signaling
mcoc04114
Oocyte meiosis
mcoc04140
Autophagy - animal
mcoc04144
Endocytosis
mcoc04150
mTOR signaling pathway
mcoc04151
PI3K-Akt signaling pathway
mcoc04152
AMPK signaling pathway
mcoc04211
Longevity regulating pathway
mcoc04213
Longevity regulating pathway - multiple species
mcoc04510
Focal adhesion
mcoc04520
Adherens junction
mcoc04550
Signaling pathways regulating pluripotency of stem cells
mcoc04730
Long-term depression
mcoc04913
Ovarian steroidogenesis
mcoc04914
Progesterone-mediated oocyte maturation
mcoc05200
Pathways in cancer
mcoc05202
Transcriptional misregulation in cancer
mcoc05205
Proteoglycans in cancer
mcoc05214
Glioma
mcoc05215
Prostate cancer
mcoc05218
Melanoma
mcoc05224
Breast cancer
mcoc05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
mcoc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
116102373 (Igf1r)
04014 Ras signaling pathway
116102373 (Igf1r)
04015 Rap1 signaling pathway
116102373 (Igf1r)
04066 HIF-1 signaling pathway
116102373 (Igf1r)
04068 FoxO signaling pathway
116102373 (Igf1r)
04151 PI3K-Akt signaling pathway
116102373 (Igf1r)
04152 AMPK signaling pathway
116102373 (Igf1r)
04150 mTOR signaling pathway
116102373 (Igf1r)
09133 Signaling molecules and interaction
04081 Hormone signaling
116102373 (Igf1r)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
116102373 (Igf1r)
04140 Autophagy - animal
116102373 (Igf1r)
09143 Cell growth and death
04114 Oocyte meiosis
116102373 (Igf1r)
09144 Cellular community - eukaryotes
04510 Focal adhesion
116102373 (Igf1r)
04520 Adherens junction
116102373 (Igf1r)
04550 Signaling pathways regulating pluripotency of stem cells
116102373 (Igf1r)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
116102373 (Igf1r)
04914 Progesterone-mediated oocyte maturation
116102373 (Igf1r)
09156 Nervous system
04730 Long-term depression
116102373 (Igf1r)
09149 Aging
04211 Longevity regulating pathway
116102373 (Igf1r)
04213 Longevity regulating pathway - multiple species
116102373 (Igf1r)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
116102373 (Igf1r)
05202 Transcriptional misregulation in cancer
116102373 (Igf1r)
05205 Proteoglycans in cancer
116102373 (Igf1r)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
116102373 (Igf1r)
05214 Glioma
116102373 (Igf1r)
05218 Melanoma
116102373 (Igf1r)
05215 Prostate cancer
116102373 (Igf1r)
05224 Breast cancer
116102373 (Igf1r)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
116102373 (Igf1r)
01522 Endocrine resistance
116102373 (Igf1r)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcoc01001
]
116102373 (Igf1r)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
mcoc04090
]
116102373 (Igf1r)
Enzymes [BR:
mcoc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
116102373 (Igf1r)
Protein kinases [BR:
mcoc01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
116102373 (Igf1r)
CD molecules [BR:
mcoc04090
]
Proteins
116102373 (Igf1r)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Insulin_TMD
B2
Motif
Other DBs
NCBI-GeneID:
116102373
NCBI-ProteinID:
XP_031242829
LinkDB
All DBs
Position
Unknown
AA seq
1373 aa
AA seq
DB search
MKSGSGGGSPTSLWGLVFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGFLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTIDWSLILDAVSNNYIVGNKPPKECGD
LCPGTLEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSVCGKRACTENNECCHPECLGSCH
TPDDNTTCVACRHYYYKGVCVPACPPGTYRFEGWRCVDRDFCANIPNAESSDSDGFVIHD
GECMQECPSGFIRNSTQSMYCIPCEGPCPKVCGDEEKKTKTIDSVTSAQMLQGCTILKGN
LLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYS
FYVLDNQNLQQLWDWNHRNLTVRSGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINT
RNNGERASCESDVLRFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYD
GQDACGSNSWNMVDVDLPPNKEGEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKS
EILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPTLPNGNLSYYIVRWQRQPQDGYLYR
HNYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGDKGPCCACPKTEAEKQAEKEEAEYR
KVFENFLHNSIFVPRPERRRRDVMQVANTTMSSRSRNTTVADTYNITDPEEFETEYPFFE
SRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVT
WEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPG
NYTARIQATSLSGNGSWTDPVFFYVPAKTTYENFMHLIIALPVAILLIVGGLVIMLYVFH
RKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAK
GVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIM
ELMTRGDLKSYLRSLRPEVEQNNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAA
RNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSF
GVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPS
FLEIIGSIKDEMEPSFQEVSFYYSEENKPPEPEELEMELEMEPENMESVPLDPSASSASL
PLPERHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRANERALPLPQSSTC
NT seq
4122 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcgtgtttctctcc
gccgcgctctcgctctggccgacgagtggagaaatctgtgggcctggaattgacatccgc
aacgactatcagcagctgaagcgcctggaaaactgcacggtgatcgagggctttctccac
atcctgctcatctccaaggccgaggactaccgaagctaccgcttccccaagctcaccgtc
atcactgagtacttgctgctgttccgagtggccggcctcgagagcctgggagaccttttc
ccgaacctcacggtcatccgtggctggaaactcttctacaactacgcactggtcatcttc
gagatgaccaatctcaaggatattgggctttataatctgaggaacataactcggggggcc
atcaggattgagaagaatgccgatctctgttacctctccaccatagactggtctctcatc
ttggatgcggtgtccaataactacattgtggggaacaagcccccaaaagaatgtggggac
ctatgtccagggacattggaggagaagcccatgtgtgagaagaccactatcaacaatgag
tacaactaccgctgctggaccacaaatcgctgccagaaaatgtgcccaagtgtgtgtggg
aagcgagcctgcaccgagaacaacgagtgctgccacccggagtgcctgggcagctgccac
acgcccgacgacaacacaacctgtgtggcctgcagacactactactacaaaggtgtgtgt
gtgcctgcctgcccgcctggcacctacaggttcgagggctggcgctgtgtggaccgcgat
ttctgtgccaacatccccaacgccgagagcagtgactcggatggcttcgtcatccatgac
ggcgagtgcatgcaggagtgtccctcgggcttcatccgcaacagcacccagagcatgtac
tgtatcccctgtgaaggcccctgccccaaagtctgcggcgatgaagaaaagaaaacgaaa
accatcgattcggttacttctgctcaaatgctccaaggatgcaccatcttgaagggcaat
ctgcttattaacatcaggcgaggcaataacattgcctcagaattggagaacttcatgggg
ctcatcgaggtggtgactggctatgtgaagatccgccattctcatgccttggtctccctg
tccttcctgaagaacctgcgtctcatcttaggagaggagcagctagaagggaactactcc
ttctatgtcctggacaaccagaacttgcagcagctgtgggactggaaccaccggaacctg
actgtcaggtcggggaaaatgtacttcgctttcaatcccaagctgtgtgtctctgaaatt
tatcgcatggaggaagtgaccggaaccaagggacgccagagcaaaggggacataaacacc
aggaacaacggagagcgagcttcctgtgaaagtgatgtcctccgtttcacctccaccacc
acctggaagaaccgcatcatcataacatggcaccggtaccggccgccagactaccgggat
ctcatcagcttcacagtttactacaaggaggcaccctttaaaaatgttacggaatatgat
gggcaggacgcctgtggctccaacagctggaacatggtggatgtggacctgcctccgaac
aaggagggggagcctggcattttactgcatgggctgaagccctggacccagtatgctgtc
tatgtcaaggctgtgaccctcaccatggtagaaaacgaccacatccgtggggccaaaagt
gaaatcttgtacattcgcaccaatgcttcagttccttccattcccctagatgtcctctca
gcatcaaactcttcctctcaactcattgtgaagtggaatcccccaactctacccaacggt
aacttgagttactacattgtgaggtggcagcggcagccacaggatggctacctgtaccgg
cacaactactgctccaaagacaaaatacctatcagaaagtatgctgatggtaccattgat
gtggaggaagtgacagaaaaccccaagacagaagtgtgtggtggtgataaaggaccatgc
tgtgcttgtcctaaaactgaagctgagaagcaggctgagaaggaggaggccgagtaccgt
aaagtctttgagaatttccttcacaattccatctttgtgcccagacccgaaaggaggcgg
agagacgtcatgcaggtggccaacaccaccatgtccagccgaagcaggaacaccacagta
gccgacacctacaacatcacagacccggaggagtttgagacagagtaccctttctttgag
agcagagtggataacaaggagaggactgtcatttccaacctccggcctttcactctgtac
cgcatcgatatccacagctgcaaccacgaggctgagaagctgggctgtagcgcctccaac
tttgtctttgcgagaaccatgccagcagaaggagcagatgacattcctggtccggtgacc
tgggagccaagacctgaaaactccatctttttaaagtggccagaacccgagaacccgaat
ggattaattctaatgtatgaaataaaatacggatctcaagtggaggatcagcgggaatgt
gtgtccagacaagagtacaggaagtacggaggggccaaacttaaccgtctaaacccaggg
aactatacagcccggattcaggctacctccctctctgggaatgggtcgtggacagatcct
gtgttcttctatgtcccagccaaaacgacgtatgagaacttcatgcatctgatcattgct
ctgccagttgccatcctgctgattgtgggggggctggtaatcatgctgtatgtcttccat
agaaagagaaataacagcaggttgggcaatggagttctgtacgcctctgtgaaccctgag
tatttcagcgcagctgatgtgtatgtgcctgatgaatgggaggtagctcgagagaagatc
accatgaaccgggagctcggacaagggtcctttgggatggtctatgaaggagtggccaag
ggcgtggtcaaggatgaacctgaaaccagagtggccatcaagacagtgaacgaggctgca
agtatgcgagaaagaattgagtttctcaacgaggcctcggtgatgaaggagttcaactgt
caccatgtggtccggttgctgggtgtggtatcccaaggccagcccaccctggtcatcatg
gaactaatgacacgtggcgatctcaaaagttatctccggtctctaaggccagaagtggag
cagaataatctagtcctgattcctccgagcttaagcaagatgatccagatggctggagag
attgcagatggcatggcctacctcaatgccaacaagtttgttcacagagacctggctgct
cggaactgcatggtagctgaagatttcacagtcaagattggagattttggtatgacacga
gacatctacgagacggactactaccggaaaggcgggaaggggttgctgcctgtgcgctgg
atgtccccagagtccctcaaggatggcgtcttcactactcattccgatgtctggtccttt
ggagtcgtcctctgggagattgccacactggctgagcagccgtaccagggcttgtccaac
gagcaagttcttcgtttcgtcatggagggtggccttctggacaagccggacaactgcccc
gatatgctgtttgaacttatgcgcatgtgctggcagtataaccccaagatgcgaccatcg
ttcctggagatcatcggcagcatcaaggatgagatggagcccagcttccaggaggtctcc
ttctattacagtgaggagaacaagcctcccgagccggaggagctggagatggagctggag
atggagcccgagaacatggagagcgtcccactggacccttcggcctcctcagcctccctg
cctctgcctgaaagacactcaggacacaaggctgagaatggccccggccctggtgtgctg
gttctccgtgccagttttgatgagagacagccttacgctcacatgaacgggggacgcgcc
aacgagagggccttgcctctgccccagtcctctacctgctga
DBGET
integrated database retrieval system
