Mastomys coucha (southern multimammate mouse): 116103808
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Entry
116103808 CDS
T07224
Symbol
Plce1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
mcoc
Mastomys coucha (southern multimammate mouse)
Pathway
mcoc00562
Inositol phosphate metabolism
mcoc01100
Metabolic pathways
mcoc04014
Ras signaling pathway
mcoc04015
Rap1 signaling pathway
mcoc04020
Calcium signaling pathway
mcoc04024
cAMP signaling pathway
mcoc04070
Phosphatidylinositol signaling system
mcoc04919
Thyroid hormone signaling pathway
mcoc04933
AGE-RAGE signaling pathway in diabetic complications
mcoc05205
Proteoglycans in cancer
Module
mcoc_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
mcoc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
116103808 (Plce1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
116103808 (Plce1)
04015 Rap1 signaling pathway
116103808 (Plce1)
04020 Calcium signaling pathway
116103808 (Plce1)
04070 Phosphatidylinositol signaling system
116103808 (Plce1)
04024 cAMP signaling pathway
116103808 (Plce1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
116103808 (Plce1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
116103808 (Plce1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
116103808 (Plce1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mcoc04131
]
116103808 (Plce1)
Enzymes [BR:
mcoc01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
116103808 (Plce1)
Membrane trafficking [BR:
mcoc04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
116103808 (Plce1)
Endocytosis
Macropinocytosis
Phospholipase C
116103808 (Plce1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
116103808
NCBI-ProteinID:
XP_031246085
LinkDB
All DBs
Position
Unknown
AA seq
2299 aa
AA seq
DB search
MTSEEMTASVLIPVTQRKVASVQSVAEETSEKVSDAGIPKSRAGRQGVLIPRTISQWNKH
KEESSRSNLSKVYSIARGGPVSDENHNEKCWEGNVPDSTENHSVNCNSLVQSHQHELPRS
QLCEACDSVTGGDLCLQPGIPSPLERKVLPGIQLEMGDSPMDVSPLGNQPGMVESSGPRA
DGNTAVFHFRYEADRTMSDAFHALSEKLILDDCANCVTLRGGQQNKNYMAYACKLMELTR
TCGSKNGQLKCEHCASLRDEYLCFESSCPKADDVCSGGGFGEDGFAHGPDAKTFLSSLED
FSDNCEDVDDFLKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIMRTLPSGHIGPAAWNY
VDQKKAGLIWPCGNVMGPLTTMDTRQSGSQRLSEAQWCLIYSAVRRGEETEDTLGSFLHC
SIQLPTSETVHGRIGAGPCLKQCVQDIECEYRATLQRTSIAQYITGSLLEATTSLGARSG
LLSSFGGSTGRIMLKERQPGNSMANSNPVPSSSAGISKELIDLQPLIQFPEEVASILTEQ
EQNIYRRVLPMDYLCFLTRDLSSPECQRSLPRLKASISESILTSQSGEHNALEDLVMRFN
EVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQF
MDQSDIETMRSLKDAMAQHESSVEYKKVVTRALHIPGCKVVPFCGVFLKELCEVLDGASG
LLKLFPRYSSQEEALEFVADYSGQENFLQRVGQNGLKNSEKELTINSIFQIIRSCSRSLE
MEEEDSASEGSDSRKNSLKDKTRWQFIIGDLLDSENDIFEKSKECDPHGSEESQKAFDHG
TELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWMKPPTASPA
GARPKLGVLSNVAEPGKFPSLGNTGVSGLVEGILDLFSVKAVYMGHPSIDIHTVCVQNKL
SSMLLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTTAVRKIRKFPDQRQQW
LRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGMSAKNAEKPNMQRNNTLGIS
TTKKKKKMLMRGESGEVTDDEMATRKAKMYRECRSRSGSDPQDVNEQEESEANVITNPPN
PLHSRRAYSLTTAGSPNLATGMSSPIRPVSSPVLSSSNKSPSSAWSSSSWHGRIRGGMRG
FQSFMVSDSNMSFVEFVELFKSFSIRSRKDLKDIFDIYSVPCHRSALESAPLYTNLTIEE
NTSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSLGVF
GVGILQLNDFLVNCQGEHCTYDEILSLIQKFEPNISMCHQGLLSFEGFARFLMDKDNFAS
RNDESQENEKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSIELDCWD
GDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFITSDLPIIISIENHCSLPQQRKMAEIFK
SVFGEKLVAKFLFETDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASM
QAQAFTGGNANPPPASNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCADKLQFEYNEE
VPKRIKKADNSSGNKAKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLST
LNSSGSSRGKERKSRKSIFGSNPGRLSPGETASFNRTSGKSSCEGIRQTWEESSPLSPST
SLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNPLM
FWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPALWDKSCPMYQKFSPLERDL
DTMDPAIYSLTIISGQNVCPSNSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQ
FLFRVHFEDLVFLRFAVVENNSSAITAQRIIPLRALKRGYRHLQLRNLHNEILEISSLFI
NSRRMEENPSGSTMPASLMFNTEERKCSQTHKVTVHGVPGPEPFAVFTINEGTKAKQLLQ
QILAVDQDTKLTATDYFLMEEKHFISKEKNECRKQPFQRAVGPEEDIVQILNSWFPEEGY
VGRIVLKAQQEALEEKSIVHDDREVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQD
VIQQTLCKAKYSYSILNNPNPCDYVLLEEVMKDVPNKKSSTPKSSQRILLDQECVFQAQS
KWKGAGKFILKLKEQVQASREDKRRGISFASELKKLTKSTKQSRGLTSPPQLVASESVQS
KEEKPVGALASGDTVAYQQ
NT seq
6900 nt
NT seq
+upstream
nt +downstream
nt
atgacgtccgaagaaatgaccgcttccgtcctcatccctgtgacccaaaggaaagtggct
tctgtccagtcagtggcagaagagacgagtgaaaaagtctcagatgctgggattcctaag
tcacgcgctggcaggcagggtgtactcatccctcgaaccatctcacagtggaacaaacac
aaggaagagtcttctagaagtaatttgtccaaggtctactcaatagcgaggggaggacca
gtcagtgatgagaatcacaatgaaaagtgctgggagggaaatgtaccggattccacggaa
aaccactccgttaactgcaacagcttagtgcaaagccaccagcatgagcttccccggagc
cagctttgtgaagcctgtgattctgtcacaggaggagacctgtgcttgcagcctgggatt
ccttctccactggaaaggaaggtgctccctggaattcaactggagatgggggactctccc
atggacgtgagccctttgggaaatcagcctgggatggtggagtccagcggacctcgcgct
gacggcaacacggcggtgtttcatttccgttatgaagctgacaggacaatgtcggatgct
tttcatgccctgtcagaaaaattaattttggatgactgtgcaaattgtgttactcttcgt
ggggggcagcaaaataaaaattacatggcgtatgcttgtaaactgatggaactgacaaga
acctgtggtagtaagaatgggcagctgaagtgtgagcattgtgcctcgctgcgtgatgaa
tacctgtgctttgaaagctcctgcccgaaggcggacgacgtctgctcaggtggtggcttt
ggcgaggacggcttcgctcacggccctgatgccaagacttttctgagctctctggaggat
ttctctgataattgtgaagacgtagacgattttttgaaaagcaaaaaggagcggtccact
ttgttagtccggaggttttgtaaaaatgacagggaagttaagaagtctgtgtataccggg
acaagagcaatcatgagaactctgccttctggccatattgggccggctgcttggaattat
gttgatcagaagaaagctggtctcatatggccttgtgggaatgtaatgggacctctgaca
acaatggacacaagacaaagtgggagccaaaggctgtctgaagcccagtggtgtctgatc
tacagtgccgtgagaagaggggaagagacagaagatacgcttggatcttttctccattgc
tccatacagctcccaacctctgagacagtccatggcaggattggagctggtccctgctta
aagcaatgtgtgcaagacatcgaatgtgagtaccgcgccaccctccaaaggacgtccata
gctcagtacatcaccggctctctcctagaggcaaccacatctttaggagcaagaagcggc
cttctcagttccttcggaggatccacgggacgaataatgctgaaagaacgccaaccgggc
aactctatggccaattccaatcctgttccttcaagttctgctggaatcagcaaagagctg
attgatctccagcccctcattcagttcccagaggaagtggccagcatcttaacagaacag
gaacagaacatttaccgcagggtcctgcccatggactacctctgtttcttaacccgggac
ttgagttcacctgaatgccagagatcactgccccgtctcaaagcatccatctcagaatca
atcctcacctctcaaagtggagaacacaatgctcttgaagaccttgtgatgagatttaac
gaggtaagctcctgggtgacctggctgatcctcacggcaggctctatggaggagaagcgg
gaagtcttctcttatttggtgcatgtggccaaatgctgctggaacatgggcaactacaac
gctgtcatggagttcctggcaggcctcaggtcaaggaaagttctaaagatgtggcagttc
atggaccagtcggacattgagaccatgcggagcctgaaagatgccatggctcagcatgag
tcctccgtggagtacaagaaggtagtgacccgagccttgcacatccccggctgcaaagtg
gttcccttctgtggggtgttcctgaaggagctctgtgaggtgcttgatggtgcctctggc
ctcctgaagctcttcccacggtacagctcccaagaagaagccctggagtttgtagccgat
tacagtggacaagagaacttcttacaacgagtggggcagaatggcttgaagaattcagag
aaggagctcaccatcaacagcatcttccagatcatccggagctgcagccgaagcttggaa
atggaggaggaggatagcgccagcgaagggagcgactctaggaaaaactccctgaaggac
aaaacccgatggcagtttataattggagatttgctggattcggaaaatgacatctttgag
aagtccaaggagtgtgaccctcatggatcagaggagtcacagaaagcttttgaccatggg
acagagctcatcccatggtacgtgctgtccatccaagcggatgtgcaccagttcctcttg
cagggggccacagtcatccactatgaccaggacacacatctctctgcccgctgctttctc
cagttgcagcctgacaatagcaccttgacctggatgaagcctcccactgcctccccagct
ggtgccagacccaagcttggtgtgcttagtaacgtggctgagcccggcaaattcccatcg
ctgggcaacactggggtgagcggcctggtggagggaatcctggacctgttttcagtgaag
gctgtgtacatgggacaccctagcattgatatacacactgtgtgtgtccagaacaaactt
agtagcatgcttctgtcagagactggggtgacactgctctatgggcttcagaccaccgac
aataggttattgcactttgtggcaccaaagcacacagccaagatgcttttcagtggattg
ctggaactcactacagcagtgagaaagataaggaagttccctgaccaaagacagcagtgg
ctccgcaaacagtacgtcagcctctatcaggaggacggtcggtatgaaggcccaaccttg
gcgcatgctgtggagttgtttggtggtaggcgatggagcactagaaaccccagccctggg
atgtcagcaaagaatgctgagaagcccaacatgcagagaaacaacaccctgggcataagc
accaccaagaaaaagaagaaaatgctcatgaggggagagagtggagaggtgacggacgac
gagatggctacccgcaaggccaagatgtacagagagtgtcgaagccggagcggctctgat
cctcaagacgttaacgaacaagaagagtcggaggccaatgtcatcactaaccctcccaac
cccctccattccagaagggcctactctttgaccacggctgggtcccccaacttggctacc
gggatgtcatctcccatcaggccagtctcttcccccgtgctgtcttcttcaaacaagagt
ccatccagtgcctggagcagcagcagctggcatgggcggatcagaggaggaatgagaggt
ttccagagcttcatggtctcagacagtaacatgagtttcgttgaattcgttgagctgttc
aagtcattcagcataaggagccgcaaggacttgaaagacatctttgacatctactccgta
ccctgccatcggtctgccttggagtcagccccactgtacaccaacctgacaatcgaagaa
aataccagtgaccttcagcctgacctagatttgctgactagaaacgtctccgacttaggg
ctgttcattaagagtaaacagcagctttctgacaaccagaggcagatatctgatgctatc
gctgctgcaagcatcgtgaccaatggcactgggattgaaagcacatcgctgggagtattt
ggagtcggcatactccagctcaatgacttcctggtgaattgccaaggagaacactgcacg
tatgatgaaatcctcagcctcatccagaaattcgagcctaacatcagcatgtgtcatcaa
ggcctattgtcttttgaagggtttgcaaggtttctgatggataaagacaatttcgcctca
agaaatgacgagtcacaggagaacgagaaagagctgcagctacccctctcctactattac
attgaatcttcacataacacctacctcaccggccatcagctcaagggggagtcctctgtg
gagctctatagccaggtccttctgcaaggatgtagaagcatagagctggactgctgggat
ggagatgatgggatgcccatcatttatcatggacatacactgacaaccaagatccctttc
aaggaagtggtggaagccatcgatcgcagtgccttcatcacctctgacctgccaatcatc
atatccattgagaaccattgttccttgcctcaacaacgaaaaatggcagaaattttcaag
agtgtgtttggagaaaagctggtggctaagttcttattcgagaccgatttctcagatgac
ccaatgcttccctcacctgaccaacttagaaggaaagtgcttctcaaaaacaagaagcta
aaggcccatcagacacctgtcgacatcctaaaacaaaaggctcatcagttagcatccatg
caagcacaggctttcactggcgggaatgccaacccgccacctgccagtaatgaggaagag
gaagatgaggaggatgaatatgattatgattacgagtccctttccgacgacaatattctg
gaagacagacctgagaacaaatcatgtgctgacaagcttcagtttgagtacaatgaagaa
gtccccaagaggataaagaaggcagacaactcctctggcaataaggcaaaggtgtatgac
atggaactgggagaagagttttaccttcctcagaacaaaaaagaaagcaggcagattgca
ccagagctctctgacctcgtcatctattgccaggcagtaaaatttccaggcctgtcaact
ctaaattcatctggctctagcagagggaaagaaaggaaaagcaggaagtccatttttggc
agcaatcctggcagactgagcccaggggagacagcgtcatttaacagaacatctggaaaa
agttcctgtgaaggaattcgacaaacctgggaggaatcttctccactcagcccaagcact
tccctcagcgctatcattagaactcctaaatgctatcatatctcgtcactgaatgaaaat
gccgccaaacgtctgtgtcgcaggtattctcagaaactgatccagcacactgcttgtcag
ctgctgaggacctaccccgcagcgaccagaatcgactcctccaatcccaaccccctcatg
ttctggctccatgggatacagcttgtagctctaaactaccagacggatgaccttccttta
catttaaacgctgccatgtttgaggcgaatggtgggtgtggttatgtcttgaagcctcct
gccctgtgggataaaagctgtcccatgtaccagaagttttctccactggaaagagaccta
gacaccatggatcctgctatctactctttaactatcatctctggccagaatgtgtgccct
agtaacagcaccggaagtccgtgcattgaagttgacgtcttgggcatgcccctggacagc
tgccatttccgcacaaagcccatccatcggaacactctgaaccccatgtggaatgagcag
tttctcttccgggttcactttgaagatcttgtatttcttcgttttgcagttgtggaaaac
aacagttcggcaataacggctcagcgaatcattccactcagagctttaaaacgaggatat
cgacatcttcagctgcggaacctccacaatgaaatcttggaaatatctagcttatttata
aacagcagaaggatggaagaaaatccctctggcagtaccatgccagcctcattgatgttt
aatactgaagagaggaaatgttctcagactcacaaagtcacagtgcatggtgtcccaggt
ccagagccctttgctgttttcactataaacgaaggcaccaaggccaagcagcttctccaa
cagattttggcggttgaccaagacaccaaacttactgccacggactattttctgatggaa
gagaagcattttatatctaaggaaaagaatgaatgcaggaaacaaccattccagagagct
gtgggtccagaggaagacatcgtgcagattttaaacagctggttcccggaagaaggctac
gtaggcaggattgtcttaaaggcccaacaggaagccctggaagagaagagcatcgtccat
gatgacagagaggtgatcttgagctcggaggaggagagtttctttgtccaagtgcatgat
gtctctccagagcaacctcgaaccgtcatcaaagccccgcgtgtcagcactgcacaagat
gtgattcaacagaccttatgcaaagccaaatattcctacagcatcctaaacaaccccaat
ccatgtgattatgtgcttttggaagaggtgatgaaagacgtgcctaataagaagtcttct
accccaaagtcctcacagaggatcctcttggaccaagaatgtgtgtttcaagctcaaagc
aagtggaagggtgcagggaaattcatccttaagctaaaggagcaggtgcaggcatcccga
gaagataaaaggcggggtatctcctttgcaagtgaactcaagaaactcactaagtccact
aagcagtcccgaggactcacatcacctcctcagcttgtggcctcagaaagtgttcagagc
aaggaggagaaacctgtgggtgccttagcctctggtgacacagtggcttaccagcagtga
DBGET
integrated database retrieval system
