Mobiluncus curtisii: HMPREF0573_11487
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Entry
HMPREF0573_11487 CDS
T01257
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
mcu
Mobiluncus curtisii
Pathway
mcu00290
Valine, leucine and isoleucine biosynthesis
mcu00620
Pyruvate metabolism
mcu01100
Metabolic pathways
mcu01110
Biosynthesis of secondary metabolites
mcu01210
2-Oxocarboxylic acid metabolism
mcu01230
Biosynthesis of amino acids
Module
mcu_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mcu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
HMPREF0573_11487
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
HMPREF0573_11487
Enzymes [BR:
mcu01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
HMPREF0573_11487
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
ADI67806
UniProt:
D6ZGP8
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All DBs
Position
1674265..1675893
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AA seq
542 aa
AA seq
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MKTTTQPIEIYDTTLRDGAQMEGISLSVADKLNIAQALDDLGVSFIEGGWPGAIPKDTEF
FALALSKLQLRHATLAAFGATRKVGTKASEDPQVLALLESGAPVITLVAKSDLRHVTDAL
KTTGQENLAMVRDTVQFLVKEGRRVFLDAEHYFDGLTHDAEYGLKVLKAAGEAGAETVVL
CDTNGGNLPSSIGAKVMEARDYLDKNGLTQVKIGIHTHNDTGCAVANAMAAIEAGAAQVQ
GCVNGYGERTGNADILTLAGNIEIKLGRPALLNEKGLAELTRTSHRVAEITNLQPSKRLP
YVGDSSFAHKAGLHASAIRVNPDLYQHIDPATVGNDMRMLVSEMAGRASVQLKAKELGID
LSGTPYLTGRVVEAVKEKESHGYVFDAADASFELLVRAQGGDLPTYFEVETWRTLVQAGR
ASLSENGEAEAEATVKLRTRDGRKIVTGEGNGPVNALDHALRQALSQTYPDITNFELVDY
KVRILDTTSGTDATVRVLITTTNGDIQWTTVGVGEDVIEASWEALVESLTWGLMHLGVRP
KV
NT seq
1629 nt
NT seq
+upstream
nt +downstream
nt
atgaaaacgacgactcagccgatagagatatacgatacaactttgcgtgacggtgcccag
atggagggcatttcgctgtctgtagcggacaagctcaatattgcccaagccctcgatgat
ttaggagttagctttattgagggcggatggcccggcgcgattccgaaagacaccgagttt
ttcgcgctggcgttgtcgaaactgcagctgcgccacgcgactctggcagctttcggcgcc
acccgcaaggtgggaactaaagccagtgaggacccccaggtcctagcactgctagagtcc
ggggcaccggtgattaccctggtggcaaaatccgatttgcgtcatgttacggatgcccta
aaaactaccggtcaagagaacttagcgatggtgcgcgatacggtgcaattcctggttaag
gaaggtcggcgtgtgttcctggatgccgaacattacttcgacggcttgacccacgatgcc
gaatacgggctgaaagtgctgaaagccgccggtgaagcgggtgcggaaacggtcgtgctg
tgcgacaccaacggtggcaatctgccctctagcatcggcgcgaaagtcatggaagcccgc
gactacctggataaaaacggcttgactcaggtaaaaatcgggattcatacccacaatgac
acggggtgtgccgtggctaacgctatggctgccattgaagccggggcggcgcaggtccag
ggctgtgtgaacggctacggggaacgcaccggtaacgctgacatcctcacccttgccggc
aacattgaaatcaaactgggtcgccccgccctgctgaacgaaaaaggtctcgcggagctg
acacgcacttcgcatcgcgttgcagaaatcacgaatctgcagccgtctaagcgtctgcct
tacgtgggggattcttcgtttgcgcacaaggcaggtctgcacgcttcggctatccgcgtg
aatccagacttgtatcaacacattgatcccgcgacggtgggcaacgatatgcggatgttg
gtttctgagatggcaggacgggcatcagtgcagctgaaagccaaagagttgggcattgac
ctgtccgggacaccctacttgaccggtcgcgttgtcgaagcagtgaaggaaaaggagtct
cacggttacgtcttcgacgcggctgacgcctcctttgagctactggtgcgggcacaaggc
ggggacttaccgacctatttcgaggtcgagacgtggcgaactttggtccaggctggtcga
gcgtctctcagcgaaaacggggaagcagaagccgaagccaccgtcaagctgcggactcgt
gacggtcgcaaaattgtcaccggggaaggcaacggtccggtcaacgcgctggatcacgcg
ctgcgtcaggcattgtcccaaacctacccggacatcacgaattttgaactcgtagattac
aaagtgcggattttagacacgacttccggaacggacgcgaccgtgcgggtgctgattacc
accacgaacggagacatccaatggaccactgttggggtgggggaggacgtgattgaagcg
tcctgggaagccctcgtcgagtctctgacctggggcttgatgcatctcggggtgcgcccg
aaggtgtag
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