Methanobacterium congolense: MCBB_0026
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Entry
MCBB_0026 CDS
T04503
Symbol
leuA
Name
(GenBank) putative 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
mcub
Methanobacterium congolense
Pathway
mcub00290
Valine, leucine and isoleucine biosynthesis
mcub00620
Pyruvate metabolism
mcub01100
Metabolic pathways
mcub01110
Biosynthesis of secondary metabolites
mcub01210
2-Oxocarboxylic acid metabolism
mcub01230
Biosynthesis of amino acids
Module
mcub_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mcub00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
MCBB_0026 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MCBB_0026 (leuA)
Enzymes [BR:
mcub01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
MCBB_0026 (leuA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
PAC4
Motif
Other DBs
NCBI-ProteinID:
SCG84615
UniProt:
A0A1D3KZ76
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All DBs
Position
I:22779..24296
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AA seq
505 aa
AA seq
DB search
MYIETVKKTMNLPEKVRIFDTTLRDGEQTPGVAITVDEKIRIAKKLDKLGVDTIEVGFPV
SSPGERKAAREILKLDLNSSICGLARPLKKDLDAAIDCGVDYIHTFIGTSPLHREYKLKM
SKEEILNKAVEGVEYIKDHGITAEFSAEDATRTEFDYLKEIYTAVEDAGADCINVPDTVG
VMIPTSMNYLISELKQEINIPISVHCHDDFGLAVANSLAAVEAGAQQVHATINGLGERAG
NASLEELVMALTTRYNIKTNIQTELLVDMSEFVSRITGIKMPPNKAIVGENAFAHEAGIH
VHGVLQKAETYEPITPEMVGHTRRIVLGKHTGANAIRAKLDEYGIELNEEQFERVFNQVK
SLGDKGKCITDADLKAMAQTVLGKAKKEIVKLEGFSVMTGDNVLPTATVKLNIGGQTKTA
AKTGVGPVDAAINAIQSLVSESADIELKEYHIEAITGGTNALAEVFVIMGDKKGNKATGR
STVDDVVMASVEAVLDSINKILVER
NT seq
1518 nt
NT seq
+upstream
nt +downstream
nt
atgtatatagaaacggtaaaaaagacaatgaatctacctgaaaaggtaagaatattcgat
acaactctaagagatggagaacaaacacccggtgttgcaataacagttgatgaaaagata
agaattgcaaaaaaattggacaaactgggcgttgacacaatagaagtgggatttccagtt
tcatcacctggtgaacgaaaagcagcacgtgaaatacttaaactagatttaaactccagt
atctgcggtttggcaagacccctgaagaaagatttagatgcagccattgactgtggagtt
gactacatacacaccttcataggaacctcccccctccacagggagtacaagctcaaaatg
agcaaggaagagatccttaacaaagctgttgaaggggttgaatacataaaggatcatggt
ataacagcagaattttcagctgaagatgccacaagaacagaattcgactacttgaaggag
atctacactgcagtggaggatgcaggtgcagactgtataaacgtgcctgacacagttggt
gtcatgataccaacctcaatgaactacctcatatctgagcttaagcaggagatcaacatt
cccataagtgtgcactgtcatgatgacttcggactggcagttgcaaactccctggctgca
gttgaagcaggtgcccagcaggtgcacgcaaccatcaacggactgggggaacgtgcagga
aacgcatcccttgaagaacttgtaatggcactcacaacccggtacaatatcaagaccaac
atccagaccgaactcctggttgacatgtcagaattcgtatccaggatcacgggtataaag
atgcctccaaacaaggccatcgttggagaaaatgcattcgcacatgaggcaggtatccac
gtccatggagtgctccaaaaagctgaaacatacgagccaataacccctgaaatggtcgga
cacacaaggagaatagttctgggaaaacacacaggtgcaaatgcaataagggcaaaactc
gatgaatacggaatagaactaaacgaggaacagttcgaaagggttttcaatcaggttaaa
agtcttggagataagggtaaatgtattacagatgctgatctgaaggcaatggctcaaaca
gtccttggaaaagccaagaaagagatagtgaaacttgaaggattctcagtgatgacaggg
gacaacgtgcttccaactgcaacagtcaagctcaacataggcggacaaacaaaaaccgct
gcaaaaactggagttggccctgttgatgcagccataaatgcaatacaaagccttgtaagt
gaaagtgcagacatagaactcaaggagtaccacattgaagccataaccggtggtacaaat
gcactggctgaagttttcgttataatgggtgataaaaagggtaacaaagcaacaggaaga
tcaacagttgacgacgtggtaatggccagcgtggaagctgttctggattccataaacaag
atccttgttgaacgataa
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