Mycobacterium canettii CIPT 140070008: BN43_10556
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Entry
BN43_10556 CDS
T02420
Symbol
hemD
Name
(GenBank) Putative uroporphyrin-III C-methyltransferase HemD
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mcv
Mycobacterium canettii CIPT 140070008
Pathway
mcv00860
Porphyrin metabolism
mcv01100
Metabolic pathways
mcv01110
Biosynthesis of secondary metabolites
mcv01120
Microbial metabolism in diverse environments
mcv01240
Biosynthesis of cofactors
Module
mcv_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mcv_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mcv00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
BN43_10556 (hemD)
Enzymes [BR:
mcv01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
BN43_10556 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
BN43_10556 (hemD)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
CCK54456
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Position
600993..602690
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AA seq
565 aa
AA seq
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MTIMTRGRKPRPGRIVFVGSGPGDPGLLTTRAAAVLANAALVFTDPDVPEPVLALIGTDL
PPVSGPAPAEPVAGNGDAAGGGSAQEQGRAASAVVSGGPDIRPALGDPADVAKTLTAEAR
SGVDVVRLVAGDPLTVDAVISEVNAVARTHLHIEIVPGLAASSAVPTYAGLPLGSSHTVA
DVRGDVDWDALAAAPGPLILQATASHLAESARSLIDHQLAESTPCVVTAHGTTCQQRSVE
TTLQGLTDPAVLGAADPACSANGRDSQAGPLIVTIGKTVTSRAKLNWWESRALYGWTVLV
PRTKDQAGEMSERLTSYGALPVEVPTIAVEPPRSPAQMERAVKGLVDGRFQWIVFTSTNA
VRAVWEKFGEFGLDARAFSGVKIACVGESTADRVRAFGISPELVPSGEQSSLGLLDDFPP
YDSVFDPVNRVLLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPATTREMIKTGG
FDAVCFTSSSTVRNLVGIAGKPHARTIIACIGPKTAETAAEFGLRVDVQPDTAAIGPLVD
ALAEHAARLRAEGALPPPRKKSRRR
NT seq
1698 nt
NT seq
+upstream
nt +downstream
nt
gtgacaatcatgacgcgagggcgtaagccgagaccgggccgcatcgttttcgtgggctcc
ggtccgggcgaccccggcttgcttacgacacgggctgccgcggtgctggccaacgccgcg
ctggtgttcaccgatcccgacgtaccggagccggtgctggcgctgatcggcacggatctg
ccccccgtgtccggcccggcgcccgccgagccggttgccgggaacggcgatgcggccggc
ggaggaagtgcgcaggaacaaggccgggccgcgtccgcggtagtctccggtggtcctgac
atccgcccggcgctgggcgatcccgccgatgtggccaagacgctgaccgccgaggcccgt
tcgggtgtcgacgtggtgcggctggtggcgggcgatccgctcacggtggatgcggtaatc
agcgaggtgaacgccgtcgcacgcacccacctgcacatcgaaatcgtgcccggcctggcc
gccagcagcgcggtcccgacctatgccgggttgccgctgggttcgtcgcacaccgtcgcc
gacgtgcgcggcgatgtggactgggacgcgctggctgccgcacccgggccgctgatcctg
caggccaccgcatcgcatctagccgaatcggcccgcagcctgatcgatcaccagctggcc
gagtccactccgtgcgtggtgaccgcacacggcaccacctgtcagcagcgttcggtcgag
accacacttcagggattgaccgacccggcagtcctgggcgctgccgaccccgcgtgctcc
gcaaacgggagggactcccaggccggaccgctgatagtgaccatcggcaagacggtgacc
agtcgggcaaagctgaactggtgggagagccgcgctctctacggctggacggtgttggtg
ccgcgcaccaaggaccaggccggcgagatgagcgagcggctcacgtcgtacggcgcgctg
ccggtggaggtgccgaccatcgccgtcgagccgccgcgcagccccgcgcagatggagcgc
gccgtcaagggcctggtcgatggccgattccagtggatcgtgttcacctccaccaacgcg
gtgcgtgcggtgtgggagaagttcggcgagttcggtttggatgcccgcgcgttctccggg
gtgaagatcgcctgtgtcggcgagtcgacggccgaccgggtgcgcgccttcggaatcagt
cccgagctggtgccctccggggagcagtcctcgcttggcttgctagacgacttcccgccc
tacgacagcgttttcgacccggtgaaccgggttttgctgccgcgcgccgacatcgccacc
gaaacgctggccgagggactgcgagagcgtggctgggagatcgaggacgtcaccgcctac
cggaccgtgcgggccgcgccgccgccggccactacccgggaaatgatcaagacgggcggg
tttgacgcggtatgtttcacctccagctcgacggtgcgaaacctggtcggcatcgccggc
aagccgcacgcgcggacgatcatcgcctgcatagggccaaagaccgccgagaccgcagcc
gagttcggcttgcgggtcgatgtccagccggacaccgccgccatcggcccgctggtcgat
gcgctggccgagcatgccgcccggttgcgcgctgagggtgcgctgcccccgccgcgcaag
aagagccgcaggcgctag
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