Mycobacterium canettii CIPT 140070017: BN45_51403
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Entry
BN45_51403 CDS
T02422
Symbol
leuC
Name
(GenBank) Putative 3-isopropylmalate dehydratase (large subunit) LeuC (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI)
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mcz
Mycobacterium canettii CIPT 140070017
Pathway
mcz00290
Valine, leucine and isoleucine biosynthesis
mcz00660
C5-Branched dibasic acid metabolism
mcz01100
Metabolic pathways
mcz01110
Biosynthesis of secondary metabolites
mcz01210
2-Oxocarboxylic acid metabolism
mcz01230
Biosynthesis of amino acids
Module
mcz_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mcz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
BN45_51403 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
BN45_51403 (leuC)
Enzymes [BR:
mcz01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
BN45_51403 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
BN45_51403 (leuC)
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Gene cluster
GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
CCK65164
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All DBs
Position
complement(3438283..3439704)
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AA seq
473 aa
AA seq
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MALQTGEPRTLAEKIWDDHIVVSGGGSAPDLIYVDLHLVHEVTSPQAFDGLRLAGRRVRR
PELTLATEDHNVPTVDIDQPIADPVSRTQVETLRRNCAEFGIRLHSMGNIEQGIVHVVGP
QLGLTQPGMTIVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFKTMAVNVDGR
LPDGVSAKDIILALIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTICNMSIEAGARAGMV
APDETTYAFLRGRPHAPTGAQWDTALAYWQRLRTDVGAVFDTEVYLDAASLSPFVTWGTN
PGQGVPLAAAVPDPQLMTDDAERQAAEKALAYMDLRPGTAMRDIAVDAVFVGSCTNGRIE
DLRVVADVLRGRKVADGVRMLIVPGSMRVRAQAEAEGLGEIFTAAGAQWRQAGCSMCLGM
NPDQLASGERCAATSNRNFEGRQGAGGRTHLVSPAVAAATAVRGTLSSPADLN
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
atggcgttgcagaccggcgagccacgcacactggccgagaagatttgggacgaccacatt
gtggtatcaggcgggggctctgcgcccgacctgatctacgtcgatctgcatctggtgcat
gaggtcaccagcccgcaggcgttcgacggcctgcgcctggccgggcgccgggtgcggcgg
cccgagctcaccctcgccaccgaggatcacaatgtgcccaccgtcgacatcgaccagccg
atcgccgacccggtgtcacgcacccaggtggagacgttgcgccgaaactgcgccgaattc
ggaatccggctgcattcaatgggcaatatcgagcagggcatcgtgcacgtcgtcggaccg
caattgggtctcacccagccgggaatgacgatcgtctgtggcgacagccacacctcaacc
cacggcgcattcggcgcgttggcgatgggcatcggtacgtcggaggtcgagcacgtgctg
gccacccagacgctgccgctgcggccgttcaagaccatggcggtcaacgtcgatgggcgg
ctgcccgacggtgtgtcggccaaggacatcatcctggcgttgatcgccaagatcggcacc
ggcggcggccaggggcatgtcatcgaataccggggcagcgccatcgaatcgctgtccatg
gaaggccggatgacgatctgcaacatgagcatcgaagccggcgctcgtgcgggcatggtg
gctccggacgaaaccacctacgcgttcttgcgtggtcgtccgcacgcacccaccggtgcc
cagtgggacaccgcactcgcctactggcaacggcttcgcaccgacgtcggcgccgttttc
gacaccgaggtgtatctggacgccgcgtcgttgagcccgtttgtcacctggggcaccaac
ccaggccaaggggtaccgctggcggccgcggtgccagatccgcaactgatgaccgacgac
gccgagcggcaggccgccgagaaagcattggcctacatggaccttcgacccggcaccgcg
atgcgcgacatcgcggtcgacgccgtgttcgtcgggtcgtgtaccaatgggcgcatcgaa
gatctgcgcgtggtcgccgacgtgctgcgcggccgcaaggtggccgatggcgtgcggatg
ctgatcgttccgggttcgatgcgggtacgcgcgcaggccgaagccgaagggctcggcgag
atcttcaccgccgcgggtgcgcaatggcggcaggcgggatgctcgatgtgcctgggcatg
aatcccgatcagctggcgtccggggagcgctgcgccgcgacgtccaaccgcaacttcgaa
gggcggcagggcgcgggcggccgcacacatttggtgtccccagcagtggcggccgccacc
gcggttcgcggcacactgtccagcccggccgatttgaattga
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