Methylorubrum extorquens DM4: METDI3299
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Entry
METDI3299 CDS
T00947
Symbol
purH
Name
(GenBank) bifunctional: IMP cyclohydrolase (N-terminal); phosphoribosylaminoimidazolecarboxamide formyltransferase (C-terminal)
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
mdi
Methylorubrum extorquens DM4
Pathway
mdi00230
Purine metabolism
mdi00670
One carbon pool by folate
mdi01100
Metabolic pathways
mdi01110
Biosynthesis of secondary metabolites
Module
mdi_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mdi00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
METDI3299 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
METDI3299 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mdi04147
]
METDI3299 (purH)
Enzymes [BR:
mdi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
METDI3299 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
METDI3299 (purH)
Exosome [BR:
mdi04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
METDI3299 (purH)
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Gene cluster
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Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-ProteinID:
CAX24948
UniProt:
C7CMH2
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All DBs
Position
complement(3232408..3234006)
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AA seq
532 aa
AA seq
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MPRDQIRVTRALLSVSDKTGLTDFAAALSQRGVELVSTGGTHRALTEAGLAVREVSELTR
FPEMMDGRVKTLHPAVHGGLLAVRDNPEHQAALAAHGIGAIDLLVVNLYPFEETLKAGKA
YDDCVENIDVGGPAMIRAAAKNHADVAVVVDVSDYSVILAELAEHDGNLTATTRRRLAQK
AFSRTASYDAAIANWLAEVEGRDKAPTFKALGGTLAQSLRYGENPHQSAAFYRLPGTLRP
GIATARQVQGKELSYNNLNDTDAAYECVAEFDPARTAAVAIIKHANPCGVAEGPDLLAAY
EQALACDPTSAFGGIVALNRPLDATAARKIVEIFTEVIIAPDASEEALAIVGAKKNLRLL
LAGGLADPRAKGEVIRTVAGGFLVQGRDALSVDDMDLKVVTKRAPSEAELADMRFAYRVA
KHVKSNAIVYAKGGATVGIGAGQMSRVDSSITAARKAAEAAQRLGLSESLAKGSAVASDA
FFPFADGLLAAAEAGATAVIQPGGSMRDDEVIRAADEAGLAMVFTGVRHFRH
NT seq
1599 nt
NT seq
+upstream
nt +downstream
nt
atgccgcgcgaccagatccgggtcacccgcgccctcctttccgtttcggacaagaccggg
ctcacggacttcgctgcggcgctgagccaacgcggcgtcgaactagtctcgaccggtggc
acccaccgcgcgctgaccgaagcgggtctcgccgtccgggaagtctccgagctgacgcgc
ttccccgagatgatggacggccgggtgaagacgctgcatccggcggttcatggcggcctg
ctcgcggtgcgcgacaaccccgagcatcaggcggctttggccgcccacggcatcggcgcg
atcgacctgctcgtggtcaacctctacccgttcgaggaaacgctgaaggccggcaaggcc
tatgacgactgcgtcgagaacatcgatgtcggcggcccggcgatgatccgcgcggcggcc
aagaaccatgccgacgtcgccgtggtggtcgatgtttcggactacagcgtcatcctcgct
gaactcgcggagcatgacggcaacctcaccgccaccacccgccgcaggctggcgcagaag
gcgttctcgcgcaccgcctcctacgacgcggcgatcgccaactggctcgccgaagtcgag
ggacgcgacaaggccccgaccttcaaggcgctcggcggaacgctcgcccagagcctgcgc
tacggcgagaacccgcaccaatcggccgccttctaccgcctgcccggcaccctgcgcccc
ggcatcgccaccgctcggcaggtccagggcaaggaactgtcctacaacaacctcaacgac
accgacgccgcctacgaatgcgtcgccgagttcgaccccgcccgcacggcggcggtggcg
atcatcaagcacgccaacccctgcggcgtggccgaagggccggatctgctggcggcctac
gagcaggcgctggcctgcgacccgacctcggccttcggcggcatcgtcgccctcaaccgg
ccgctcgacgccacggccgcgagaaagatcgtcgagatcttcaccgaggtcatcatcgcc
cccgatgcctccgaggaggcgctcgctatcgtcggcgccaagaagaacctgcggcttctc
ctcgccggcggcctcgccgatccgcgggcgaagggtgaggtcatccgcactgtggcgggc
ggcttcctggtccagggccgggatgcgctcagcgtggacgacatggacctgaaggtcgtg
accaagcgcgccccgagcgaggcggaactcgccgacatgcgctttgcctatcgggtggcc
aagcacgtgaagtcgaacgcgatcgtctacgccaagggcggcgccacggtcggcatcggc
gcaggccagatgtcgcgggtggattcctcgatcaccgccgcgcgcaaggcggcggaggcg
gcgcagcgcctcggcttgtccgagagccttgcgaagggttcggcggtggcctccgacgcc
ttcttccccttcgccgacggcctgctcgccgccgccgaggccggtgccaccgccgtgatc
cagcccggcggctcgatgcgcgacgacgaggtgatccgggccgccgacgaggccgggctc
gccatggtgttcaccggcgtgcgccacttccggcactag
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