Methylorubrum extorquens DM4: METDI5687
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Entry
METDI5687 CDS
T00947
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mdi
Methylorubrum extorquens DM4
Pathway
mdi00300
Lysine biosynthesis
mdi00550
Peptidoglycan biosynthesis
mdi01100
Metabolic pathways
mdi01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mdi00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
METDI5687 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
METDI5687 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
METDI5687 (murF)
Enzymes [BR:
mdi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
METDI5687 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
CAX27291
UniProt:
C7C8Y4
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All DBs
Position
complement(5672293..5673756)
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AA seq
487 aa
AA seq
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MNDAPLWTPAALEAATGGRLIGTPRAVTGASIDTRSLEPGDLFFAIRGEARDGHDFVRAA
LEKGAGAAVVAEARAKEFEGAGPVLAVPGEGEDPVLDAMRRLGLAARARTGAAIIAVTGS
VGKTGTKEALRHVLSAQGATHASVASYNNHWGVPLTLTRMPEDTRFGVFEIGMNHGAEIL
PLTAMVRPDVALITTVEPVHIEHFRSLSAIADAKGEIFSGLKPGGVAVINRDNPNYERLL
AHAQASRAGRVITFGEHEAADVCAHRILTRPDVSVVDATVMGIPVTYQLGTPGRHVAMNS
LGVLACIHALGADLARAALSLASLKPPVGRGERTALRIGDGEAFLVDESYNANPASIRAA
LATLAGIDTGAKGRRIAVLGDMKELGAAGEALHRELADAVAANGIDLVFAVGPLMAHLFE
ALPMPVRGTAAPTAEGVTDAVLATLRPGDAVMVKGSNSMRMVRIVEAVKARYAVAPDPRE
ASLNAVR
NT seq
1464 nt
NT seq
+upstream
nt +downstream
nt
atgaacgacgcccccctctggacacccgccgccctggaagcagccaccggcgggcgcctg
atcggcacgccgcgcgccgtcaccggcgcctcgatcgacacccgcagcctggaacccggc
gacctgttcttcgccatccgcggcgaggcgcgcgacgggcacgacttcgtgcgcgctgcc
ctggagaagggcgccggcgcggcggtggtcgcggaagcgcgagcgaaggaattcgagggc
gccggccccgtgctcgccgtgccgggggagggcgaagatccggttctggacgcgatgcgt
cgccttggtctggccgcgcgcgcccgcaccggggcagcgatcatcgcagtgacgggctcc
gtcggcaagaccggtaccaaggaagccctgcgccacgtgctctcggcgcaaggcgccacg
cacgcctcggtcgcctcctacaacaaccattggggcgtgccgctgacgctgacgcggatg
ccggaagacacccgcttcggcgtgttcgagatcggcatgaaccacggcgccgagatcctg
ccgctgaccgcgatggtgcggccggacgtggcgctgatcaccacggtcgagccggtgcat
atcgagcatttccgctcgctctcggccatcgccgacgcgaagggcgagattttttccggg
ctcaagcccggcggcgttgcggtgatcaaccgcgacaacccgaactacgagcgcctgctc
gcccacgcgcaggcctcgcgggccgggcgcgtcatcaccttcggcgagcacgaggcggcg
gatgtgtgcgcccaccgcatcctgacccggcccgacgtctcggtggtcgatgccaccgtg
atgggcattcccgtgacctaccagctcggcacgccgggccggcacgtcgcgatgaactcg
ctcggcgtgctcgcctgcatccacgcgctcggcgccgacctcgcccgcgccgccctgtcg
ctggcgagcctcaagccgccggtcgggcgcggcgagcgcaccgcgcttcggatcggggac
ggcgaggccttcctcgtcgacgagagctacaacgccaaccccgcctcgatccgcgcggcg
ctggcgacgctcgccggcatcgacaccggcgccaagggccggcgcatcgccgtgctcggc
gatatgaaggaactcggtgcggccggcgaagcgctgcaccgcgaactggcggacgcggtc
gccgcgaacgggatcgacctcgtcttcgccgtcggccccctgatggcgcacctgttcgag
gcgctgccgatgccggtgcgggggacggccgcgccgaccgccgagggcgtcaccgacgcc
gtcctcgcgaccctgcggccgggcgatgccgtgatggtgaagggctccaactccatgcgc
atggtccgcattgtcgaagcggtcaaagcccgctacgcggtcgcgccagacccgcgcgaa
gcctcgctgaacgcggttcgctaa
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