Monodelphis domestica (gray short-tailed opossum): 100012931
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Entry
100012931 CDS
T01031
Symbol
TYK2
Name
(RefSeq) tyrosine kinase 2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
mdo
Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo04217
Necroptosis
mdo04380
Osteoclast differentiation
mdo04620
Toll-like receptor signaling pathway
mdo04621
NOD-like receptor signaling pathway
mdo04630
JAK-STAT signaling pathway
mdo04658
Th1 and Th2 cell differentiation
mdo04659
Th17 cell differentiation
mdo05145
Toxoplasmosis
mdo05160
Hepatitis C
mdo05161
Hepatitis B
mdo05162
Measles
mdo05164
Influenza A
mdo05165
Human papillomavirus infection
mdo05167
Kaposi sarcoma-associated herpesvirus infection
mdo05168
Herpes simplex virus 1 infection
mdo05169
Epstein-Barr virus infection
mdo05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
mdo00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
100012931 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
100012931 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
100012931 (TYK2)
04621 NOD-like receptor signaling pathway
100012931 (TYK2)
04658 Th1 and Th2 cell differentiation
100012931 (TYK2)
04659 Th17 cell differentiation
100012931 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
100012931 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
100012931 (TYK2)
05160 Hepatitis C
100012931 (TYK2)
05171 Coronavirus disease - COVID-19
100012931 (TYK2)
05164 Influenza A
100012931 (TYK2)
05162 Measles
100012931 (TYK2)
05168 Herpes simplex virus 1 infection
100012931 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
100012931 (TYK2)
05169 Epstein-Barr virus infection
100012931 (TYK2)
05165 Human papillomavirus infection
100012931 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100012931 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mdo01001
]
100012931 (TYK2)
Enzymes [BR:
mdo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100012931 (TYK2)
Protein kinases [BR:
mdo01001
]
Non-receptor tyrosine kinases
JAK family [OT]
100012931 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
SH2
FERM_C_FAK1
ABC1
RA
RA_2
Motif
Other DBs
NCBI-GeneID:
100012931
NCBI-ProteinID:
XP_001367312
Ensembl:
ENSMODG00000005684
UniProt:
F6V3I2
LinkDB
All DBs
Position
3:430988100..431003124
Genome browser
AA seq
1193 aa
AA seq
DB search
MPLCHCAARHNDSDGDWVHPGSGLKVFLHWSNGGEQYVTYNQGTMTAEEVCIHIAKKVGI
TPLCYNLFALYDTQAQIWLPPNHLFEVTKDTNLTLQFRIRYYFRNWHGLNTQEPAVYRSM
TRNIEVSEDKIQMEQGCALLDKASFEYLFEQGKFEFVNDVASLWDLHSEAEIHHFKNESL
GMAVLHLSHLALQRGIPLEEVVRKTSFKDCIPRSFSRQIQQNNFLTKFRLRTVFQKFMRR
FHLQTVGPGHLSKQNIMFKYLATLEQLAPRFGAERFLALTLALPTEAERELCYVNSSGQT
PAGPAGSTFSLDAQVPTHEVLVMGTNGIRWRLLQEKVSELEINRPKSSFGKKSKAQKAEN
QKLSQLPTEKKDPSWTYFCDFQEITHVVVKESNVSIHRQDNKCLELTLPSPIVALSLVSL
IDGYFRLTADSSHYLCHEVAPPRLVMSIQNGIHGPLQESYVLSKLKREEVEDGLYLIRWS
SFDFHRLILTVARKDQAQGLRYKQFRIEEQGRTFQLEGWDQTFSSVRELTTALQGCTLRS
SSGSGPGSSLESFTISKCCLPRAGEISNLIITRHRPKEGPKPLNLSQLSFYQIRKDEITQ
LAHLGQGTRTNIYEGLLHVGGGMEAEDEEEENIPSEPNNNHRELRVVLKVLDPSHRDIAL
AFFETASLMSQVSHIHLAFVHGVCVRGSENIMVAEYVEHGPLDVCLRREKGHVPVAWKIT
VAQQLASALSYLEDKNLVHGNVCAKNILLARRGLGDGTQPFIKLSDPGVSVTALSREERV
ERIPWIAPECVPSGTGLSTAADKWSFGTTLLEICFDGEAPLQGRTPSEKERFYEKKHRLQ
EPSCKELATLISQCLTYEANQRPSFRTILRDLTQLQPQNLSDITTMSPEFPASDPTVFQK
RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKSLKAGCSSQLLSSWQREIEILRTL
YHDHIVKYKGCCSDQGEKIVQLIMEYVPLGSLRDYLPKHSLGLAQILLFAQQICKGMSYL
HSQHYIHRDLAARNVLLENDNIIKIGDFGLAKAVPEGRDYYCVREDGDSPVFWYAMECLK
ESKFYYASDVWSFGVTLYELLTRCDYNQSPPLKFIEMIGVTQGQMTVLRLIDLLERGQRL
PCPKDCPSEIYALMKSCWESEASFRPTFEKLDPILKTFHEKYRSQAPSVFSVC
NT seq
3582 nt
NT seq
+upstream
nt +downstream
nt
atgccactatgtcactgtgctgcaagacacaatgactccgatggagactgggtccaccct
ggcagtggactcaaggttttcctccattggagcaatgggggtgaacagtatgtgacctac
aaccaaggcaccatgaccgcagaggaagtctgcatccacattgcaaagaaagtggggatc
accccactctgctacaacctttttgcattatatgatacccaggcccaaatctggctgcct
cctaaccacctttttgaggtcactaaggacaccaacctcaccctacagtttcgaataagg
tattacttccgaaactggcatggtttgaacacccaggagccagctgtgtaccgaagcatg
actagaaatattgaggtctctgaagataagatccaaatggaacaggggtgtgctttgctg
gacaaagcctccttcgagtacctctttgaacaggggaagttcgaatttgtcaatgatgtt
gcctcactttgggacctacacagtgaagcagagatacatcacttcaagaatgagagcctt
ggcatggctgtgctgcacctttcccaccttgccctgcagcgtggtatccctctggaagag
gtggtaaggaagaccagcttcaaagactgcatcccacggtccttcagtcgacaaatccaa
cagaacaatttcctgactaaattccgcctgaggactgtcttccagaagtttatgagacga
ttccatctacagacagtgggtccagggcatcttagtaaacagaacattatgttcaaatac
ctggctactctggagcagctagccccacgatttggtgctgagcgatttcttgccctaact
ttagcattacctacagaggccgaaagggagttgtgctatgttaacagcagtggacaaaca
cctgctggtccagcaggatccactttctctcttgatgctcaggttcctacccatgaggtt
ctagtaatgggtacaaatggtatccgttggaggcttcttcaggagaaggtctctgaattg
gaaattaaccgccccaaaagttcctttggtaagaagtccaaagcccagaaggcagagaac
cagaagctaagccagctgccaactgaaaagaaagacccttcctggacatatttttgtgac
ttccaagagatcactcatgttgtggtcaaggagagcaacgtcagcatccatcgtcaagac
aacaagtgcctggaactgactctcccttcacctatcgtggctctctccctggtatccctg
atagatggctatttcaggctgacagcagactctagccactacctgtgccatgaggtggct
ccccccagactggtgatgagcattcagaatggcatccatggacccctgcaggagagttat
gtactgtccaaactgaagagggaggaagtagaagatggtctctaccttattcgttggagt
tcctttgacttccaccgcctcatcctgactgtggcccggaaggaccaggcacagggtctc
cgttacaagcagttccgtattgaagagcagggccggaccttccagctggaaggctgggat
caaaccttttccagtgttcgtgaactcacaactgccttgcagggctgcacacttcgatcc
agctctggctctggtcctggatccagtctagaaagcttcaccatcagcaaatgttgcctg
cctcgagcaggagaaatctccaacctgatcatcactcggcatcgtcctaaggagggccct
aaaccactcaacttatcccagctcagcttctaccaaatccgaaaggatgaaattactcag
ttggctcatctgggccagggcacccggaccaatatttatgagggacttctgcatgtgggg
ggtggaatggaagctgaggatgaggaagaagagaacattccctcagaacccaacaacaac
catcgggagcttcgagtagtgctgaaagtgctggacccaagtcaccgtgatattgccctg
gcattttttgaaacagccagcctaatgagccaggtctcccacatccacctggccttcgtc
catggtgtttgtgtccggggctctgagaatatcatggtggcagaatatgtagagcatgga
ccactggatgtatgtctccgccgggagaagggccatgtgcctgtggcctggaagattact
gtggcccagcagcttgccagtgctctcagctacctagaggataagaacctggttcatggt
aatgtttgtgccaagaacatcctgttggcaaggcgtggccttggggatggcactcagccc
ttcatcaagctcagtgatcctggagtcagcgtcactgctctctccagggaggaaagggta
gaacgaattccctggattgctcctgaatgtgtacccagtgggactggtcttagcacagct
gctgacaagtggagctttggaacaaccctcctagagatctgctttgatggagaagcaccc
ctccagggtcgtaccccttctgagaaggagcgcttttatgagaagaaacatcggctccag
gagccctcatgcaaggaactggccacactcatcagccagtgccttacctatgaggccaac
cagcgaccttccttccgaaccatccttcgtgacctcacccagctgcagccccaaaatctc
tctgacattaccactatgagcccagagttcccagcctcagaccccaccgtttttcagaag
cgctacctaaagaagattcgagacctgggagagggccattttggcaaagtgagcctctat
tgctatgacccaactaatgatgggacaggtgagatggtggctgtgaagtctctcaaggct
ggctgcagttcccaactcttgagcagctggcaacgggagattgagatccttcggacactc
taccatgaccacatcgtcaaatacaagggctgctgcagtgaccaaggggagaagattgtc
cagctgatcatggagtatgtgccactgggcagtttgcgggactacctgcccaaacatagt
ttggggctggcccagattctgctgtttgctcagcagatctgtaagggcatgtcctacctc
cattctcaacactacatccatcgagacctggcagcccgaaatgtccttctggagaatgac
aacattatcaagattggggactttggcctggccaaggctgtgccagagggccgtgattac
tactgtgtccgggaagatggagacagccctgtcttctggtatgccatggagtgtctcaag
gaatctaagttctactatgcttcagacgtctggtcctttggggtcaccctctatgagctg
ctaacccgctgtgactacaatcagagtccccccttgaaattcattgaaatgattggggtt
acccagggccagatgactgtgctaaggcttattgacttgctagagagaggtcagagactg
ccttgtcccaaggattgtccctctgagatctatgccctcatgaagagttgctgggaatct
gaagcctcctttcgcccaacctttgagaagcttgatcccattctcaagacattccatgag
aagtacaggagtcaagcgccctccgtgtttagtgtatgctga
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