KEGG   Monodelphis domestica (gray short-tailed opossum): 100013592
Entry
100013592         CDS       T01031                                 
Symbol
APC
Name
(RefSeq) APC, WNT signaling pathway regulator
  KO
K02085  adenomatosis polyposis coli protein
Organism
mdo  Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo04310  Wnt signaling pathway
mdo04390  Hippo signaling pathway
mdo04550  Signaling pathways regulating pluripotency of stem cells
mdo04810  Regulation of actin cytoskeleton
mdo04934  Cushing syndrome
mdo05010  Alzheimer disease
mdo05022  Pathways of neurodegeneration - multiple diseases
mdo05165  Human papillomavirus infection
mdo05200  Pathways in cancer
mdo05206  MicroRNAs in cancer
mdo05210  Colorectal cancer
mdo05213  Endometrial cancer
mdo05217  Basal cell carcinoma
mdo05224  Breast cancer
mdo05225  Hepatocellular carcinoma
mdo05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:mdo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    100013592 (APC)
   04390 Hippo signaling pathway
    100013592 (APC)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100013592 (APC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100013592 (APC)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100013592 (APC)
   05206 MicroRNAs in cancer
    100013592 (APC)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100013592 (APC)
   05225 Hepatocellular carcinoma
    100013592 (APC)
   05226 Gastric cancer
    100013592 (APC)
   05217 Basal cell carcinoma
    100013592 (APC)
   05213 Endometrial cancer
    100013592 (APC)
   05224 Breast cancer
    100013592 (APC)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    100013592 (APC)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100013592 (APC)
   05022 Pathways of neurodegeneration - multiple diseases
    100013592 (APC)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100013592 (APC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mdo01009]
    100013592 (APC)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mdo03036]
    100013592 (APC)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:mdo04812]
    100013592 (APC)
Protein phosphatases and associated proteins [BR:mdo01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     100013592 (APC)
Chromosome and associated proteins [BR:mdo03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centrosome associated proteins
    100013592 (APC)
Cytoskeleton proteins [BR:mdo04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     100013592 (APC)
SSDB
Motif
Pfam: Arm_APC_u3 APC_basic EB1_binding APC_r APC_u5 APC_rep APC_u14 APC_u9 APC_u15 APC_N_CC SAMP APC_u13 Arm APC_15aa Suppressor_APC ARM_ARMC5 Sec7-like_HUS CEBP_ZZ
Other DBs
NCBI-GeneID: 100013592
NCBI-ProteinID: XP_001363397
Ensembl: ENSMODG00000013281
LinkDB
Position
6:complement(536030..703760)
AA seq 2842 aa
MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM
ASSGQIDLLERLKELNLDSSNFPGVKLRPKMSIRSYGSREGSVSSRSGECSPVPMGSFSR
RGFMNGSRESTGYLEELEKERSLLLAELEKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL
QTDMTRRQLEYEARQIRAAMEEQLGTCQDMEKRAQLRVARIQQIEKDILRIRQLLQSQPA
EAERASQSKPDHASHEAERPNEGPGAADVSVAPPAGSQGSVAQVDQETASGGSANGAYSV
PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL
HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC
WQWQEAHEQGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ
VDCEMYGLTSDHYSVTLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDL
EQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT
ENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENS
CLQTLLQHLKSHSLTIVSNACGTLWNLSARNTKDQEALWDMGAVSMLKNLIHSKHKMIAM
GSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLS
PKTSHRPKQRHKQSVYGEYALDASRHDDSRPDAFSTGNLTVLSPYLNSTVLPGSSSSRTS
LESSRSEKDRSLDRERAVALSTFHPAADSPGNPSKRLGMQLSTTTAQIAKVMEEVSAIHA
QEDQSSASTTDLHCVAEERSTLRRASAAHAHSNTYNFPKPDNSNRTCAMPYAKVEYKRSS
NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDEE
LDTPINYSLKYSDEQLNSGRQSPSQNDRWARPKHVIEDEIKQNEQRQARGQNTPFSAYSE
STDDKHMKFQSRFGQQECVSPYRSRGASGSEQNRVSSGHGINQKVNQSLCHEDDYDEDKP
TNYSERYSEEEQHEEEDRPTNYSMKYNEEEHHADQPIDYSLKYAADITPSSQKPSFSFSK
SSSVQSNKTGHISSGGNTSTAPASTKRQNQLLPSSAQNRSGHTQKTASCKAPSINQETIQ
TYCVEDTPICFSRCSSLSSLSSAEDEIGRDQTTRGSETTNTLQIAELKENSASVSTGDTG
SEVPSTSQHIRTKANRLQTTSLSPSDSTRHKAVEFSSGAKSPAKSGAQTPKSPPEHYVQE
TPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTP
PPPQTGQTKREATKSKLPSAEKRESGPRQAAVNAAVQRVQVLPDADTLLHFATESTPDGF
SCSSSLSALSLDEPFIQKDVELRLMPPVQENEHGNETEPEQLEDVSEVKEKKAEKPTESE
KDILDDSDDDDIEILEECIISAMPTKSSRKAKKPSQAASKIPPPVARKPSQLPVYKLLPS
QNRLQAQKHVSFTPGDDVPRVYCVEGTPINFSTATSLSDLTIESPPNELAGVEGTSTGAL
LGDFEKRDTIPTEGRSTDDIQIGKSSNVNTSAFDDNKTEEGEILAECINSAMPKGKSHKP
FRVKKIMDQIQQASASSSGNSKNPLDSEKKKPTSPVKPMPQSAEYRTRIRKNAESKNVNV
ERSYSDKDSKKLSLKNNARDFLDKMPNNEDRVRGSFTFDSPHHYTPIEGTPYCFSRNDSL
SSLDFDDDDVDLSREKAELKGKEAKETEAKVSNHLELTSNQQSANRAQICAKHPVERGQS
KPLLQKQSTFPQSSKDMPDRVAATDEKLQNFAIENTPVCFSRNSSLSSLSDIDQENNNNK
ESEPTKETEPPDSQGEPNRPQTSGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQEC
ISSAMPKKKRPSRFKGDDEKPSPRNMDGILAEDLTLDLRDIQRPDSEHGFSPDSENFDWK
AIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSN
KGPRILKPGEKSTLETKKIESENKGIKGGKKVYKSLITGKVRSNSEVSGQLKQPLPTNMP
SISRGRTMIHIPGIRNSSSSTSPVSKKGPSLKTPTSKSPSEGPTSSTSPRGAKPSVKSEL
SPVTRQTSQPGGSSKGPSRSGSRDSTPSRPSQQPLSRPMQSPGRNSISPGRNGISPPNKL
SQLPRTSSPSTSSTKSSGSGKISYTSPGRQMSQQNLTKQTGLSKNTSNIPRSESASKGLN
QISNSNGTNKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKETPSPTLRRKLEESASL
ESLSSSSRPDSPTKSQVQTPILSPSLPDMSLSTHSSIQTGSWRKLPPNLNPSIEFNDGRS
TKRHDIARSHSESPSRLPVNRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSE
KAKSEDEKHVSSLLGTKQTKENQGPAKGTWRKIKESEMTPISNVSQVTSSGTTNGADSKT
LIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDNVAEKVSSGNKESKDNQG
KPNGGNGSSAPARTVGLENRLNSFIQIDSPDKKAAETKSGQVNLVPAPETSETSVAERTP
FSSTSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSSAARPSQIPTPVNNSTKKRDSKTE
NTESSGTQSPKRHSGSYLVTSV
NT seq 8529 nt   +upstreamnt  +downstreamnt
atggcagcagcttcatacgatcagttgttaaaacaagttgaagcactgaagatggagaac
tcgaatcttcgacaagagctagaagataattccaatcatctaacaaaactggaaactgag
gcatctaatatgaaggaagtacttaaacagttacaaggaagtattgaagatgaagcaatg
gcttcgtctggacaaattgatttgttggagcgtctcaaagaactcaacttggacagcagc
aatttccctggagtgaagcttcggccaaagatgtctatccgttcctatggaagtagagaa
ggttctgtatcgagtcgttccggagagtgtagtcctgtacccatgggatccttttcaaga
agaggtttcatgaatggaagccgagaaagcactggatatttagaagaacttgagaaagaa
agatccctcctgcttgcagaactggaaaaagaggaaaaagagaaagactggtattatgcg
cagcttcaaaacctaacgaaaaggatagacagccttcctctaacagaaaacttctcattg
caaacagatatgactaggaggcagttggagtatgaagcaagacaaatcagagctgcaatg
gaggagcagctaggtacttgtcaggatatggagaaacgagcccagttaagagtggctaga
attcagcaaattgagaaagacatacttcgcatacgacagttattacagtcccaacctgca
gaagcagagagggcctctcagagcaagcctgatcatgcctcccatgaagccgagcggccg
aacgaaggcccgggagcggccgacgtcagcgtggcaccccctgctgggagtcagggttcc
gtggcccaagtggaccaggagacagccagcggcgggagtgctaacggtgcttactctgtt
cctcggaggctgaccagtcacctagggaccaaggtggagatggtctactccctgctgtcc
atgctcggcacccacgacaaggacgacatgtcgcgcacgctgctggccatgtcgagctcc
caggacagctgcatctccatgcgccagtcgggctgcctccccctcctcatccagctcctc
cacggcaacgacaaagactcggtgctgctgggcaactcgcgcggcagcaaggaggcgcgg
gcccgggccagcgcggcgctgcacaacatcatccactcgcagcccgacgacaagaggggc
cgccgcgagatccgcgtcctccacctcctggagcagatccgggcctactgcgagacctgc
tggcagtggcaggaggcccacgagcagggcatggaccaggacaagaatccaatgccggcc
ccggtggaacaccagatctgccctgctgtgtgcgtcctaatgaagctgtccttcgatgaa
gagcacaggcacgcaatgaacgaactcggtggcctccaagccattgctgagttactgcaa
gtcgactgcgagatgtacggcctcacgagcgaccactacagcgtcacgctgagacgctac
gccggaatggctctgacaaacttgacttttggagacgtggcaaataaggctactctgtgc
tctatgaaaggctgtatgagagcgctcgtagcccagttgaaatctgaaagtgaagactta
gaacaggtcattgcaagtgttctgaggaatttgtcttggcgagctgacgtgaatagtaaa
aagactctgcgtgaagttggaagtgtaaaagcattaatggaatgtgctttggaagttaaa
aaggaatccaccctcaaaagcgtactgagtgccttatggaatttgtccgcacattgcact
gaaaataaagcggatatctgtgctgtggacggtgctcttgcatttttggttggcacactc
acttaccggagccagacgaatactttagccatcattgagagcggaggtgggatactgagg
aatgtgtctagcttgatagccacaaatgaggaccacaggcaaatcttgagagaaaacagt
tgcttacagaccttgctacagcacttaaagtctcatagtttgacaatcgtcagcaatgca
tgtggaactctgtggaatctgtcagcgagaaacacgaaggaccaagaagctttatgggac
atgggggcggtgagcatgctgaagaacctaattcactcaaagcacaagatgattgctatg
ggcagtgctgctgccttacggaacctcatggcaaacaggcctgccaagtacaaggacgcc
aatatcatgtcgcctggttccagcttgccgtctctgcatgttagaaagcagaaggccctg
gaagccgagttagacgcccagcatttatcggagacgtttgataacatcgacaatctaagc
cccaagacgtcgcaccgccctaagcagagacataagcaaagcgtctatggggagtacgcg
ctggacgcgagtcgccacgacgacagccggccggatgctttcagcaccgggaatctgact
gtcctttcgccgtatctgaacagcacggtgctgccgggatcctcttcctcgaggaccagt
ttggaaagctctcggtctgaaaaagatcggagcctggacagagagcgagcagtcgcactg
agcacctttcacccagcagcagacagtcctggcaacccttccaaacgcctggggatgcag
ctctccaccaccacggcccagattgctaaagtcatggaggaagtatccgcgattcatgcc
caggaagaccagagttcagcatcgacgaccgacttacactgtgtagcagaagagagaagc
acattgagaagagcgtccgctgcccacgcgcattcgaatacgtacaacttccccaaaccg
gataattcaaacagaacgtgtgctatgccctatgccaaagtggagtataaaagatcttcc
aatgacagcttgaatagtgtgagcagcagtgacggctatgggaaaagaggtcagatgaaa
ccctccattgaatcctactcggaagatgacgaaagcaaattctgcagttatggccagtat
ccagctgatttagctcacaaaattcacagtgccaatcacatggatgacaatgatgaagaa
ttagataccccaatcaattatagcctcaagtattcagacgaacaattaaattctggaagg
cagagtccttcccagaacgatcgatgggccagaccgaaacacgtaatagaagatgaaatc
aaacagaatgagcagaggcaggcgaggggtcaaaacacacccttctcggcatacagtgaa
agcactgatgataaacatatgaagtttcagtcgcgttttggacagcaagaatgtgtttct
ccatatagatcaaggggagccagtggttccgagcagaatcgagtgagttcaggtcatgga
attaatcagaaagtgaaccagtctttgtgtcatgaggatgattatgatgaagacaaacca
accaactatagtgaacgttattctgaagaggaacagcatgaggaagaagacagacccacc
aattatagcatgaaatataatgaagaagaacatcatgcagatcagcctattgattatagt
ttgaaatatgcagccgacattacgccctcctcccagaagccatctttttcattctccaag
agctcatccgtacagagtaataaaacaggtcacatctcaagtggtgggaacacatcaacc
gctccagctagtaccaaaaggcagaatcagcttcttcccagttcagcgcagaacagaagt
ggtcacactcagaaaacggcctcttgtaaagcgccttctatcaaccaggaaacaatacag
acttactgtgtggaagatacaccgatatgtttttcaaggtgtagctcattatcttctttg
tcttccgctgaagatgaaataggacgtgatcagacaacccgaggctcagagactaccaac
actctacagatagcagaactaaaagaaaacagtgcaagtgtgtcaactggtgacacagga
agtgaagtgccatcaacatcgcaacacattcgaaccaaagccaacagactccaaacgaca
agtttgtctccttcagactcaaccagacataaagctgttgaattttcctcaggtgccaaa
tctccagccaaaagtggtgctcagacacccaaaagtccaccagagcattatgttcaagag
actccactcatgtttagcaggtgtacttctgtcagttcacttgatagctttgagagtcgc
tcaattgccagttctgtccaaagtgaaccctgcagtggaatggtaagtggcatcataagc
cccagcgacctcccagatagtcctggacaaaccatgccaccgagtagaagtaaaactcct
cctcctcctcagacaggacaaacgaaaagagaagccacaaaaagtaagctccccagcgct
gaaaagagagaaagcggacctcggcaggcggctgtcaatgccgctgtccagagagtccag
gtgctccccgatgcggacaccttgttacattttgcgacagaaagcactccggatggattt
tcttgttcatctagtttaagcgctctgagtctcgacgagccgttcatacagaaagatgtc
gagttaagattaatgccccccgtacaggagaatgagcatggaaatgaaacggagcctgag
cagctagaagacgtcagtgaagtcaaagagaagaaagcagagaagcctactgagtccgag
aaagacatcctggatgactctgatgacgatgatatcgaaatattagaagaatgtattatt
tctgccatgccgacaaagtcttcgcgtaaagccaaaaagccctcccaagctgcttcaaaa
ataccccctccggtggccaggaaaccaagtcagttgcctgtatacaaacttcttccttca
cagaacaggttacaagctcagaaacatgtcagttttactcctggagatgacgtgccgcgg
gtgtactgtgtcgaaggcacgcctataaacttttccaccgctacatctctcagtgatctc
acgatagaatcgcctccaaatgagttggctggtgtggaaggcactagcacaggggccctg
ttgggagattttgaaaagagggataccatccctacagaaggcagaagcacagatgacatt
cagatagggaagagttctaatgtaaatacttctgcattcgatgacaacaaaacggaggaa
ggcgagatccttgctgagtgcattaattcggctatgcctaaaggaaagagtcacaagcct
ttccgtgtgaagaagataatggaccagattcaacaagcttctgcatcttcatctggaaac
agtaagaacccactagacagcgagaagaagaaacccacgtcaccagtaaaaccgatgcca
caaagtgctgaatatagaactcgtataaggaaaaacgcagaatccaaaaatgtgaatgtg
gagagatcttactcggataaagactcaaagaaactgagcctgaaaaacaatgccagagac
tttcttgataagatgccaaacaacgaggaccgcgtgagaggaagttttacttttgactct
cctcatcactacacccccattgagggaactccttactgcttctcacgaaacgattccttg
agttctcttgactttgatgatgatgatgttgacctttctagggaaaaggcagagttgaaa
ggaaaagaagctaaggaaacagaagctaaagtcagtaaccatttggagctaacatcaaat
cagcagtcagctaatagagcacagatttgtgcaaaacatccagtagagcgaggccagtcc
aaacccttgctgcaaaaacaatccacttttcctcagtcatccaaagatatgccagaccga
gttgcagctacagatgagaagttacagaattttgccattgaaaataccccagtttgtttt
tctcgtaattcatctctgagttctctcagtgacattgaccaggaaaataacaacaacaaa
gaaagtgaacctactaaagagactgaaccccctgactcacagggggagccaaacagacct
cagacatcaggttatgctcctaagtcattccacgttgaagacactccagtgtgtttctca
agaaacagctcccttagttctcttagcatagactctgaagatgaccttttgcaggagtgt
atcagttctgcaatgccaaaaaagaaaaggccctcaaggttcaaaggtgatgatgaaaaa
cccagtcctagaaacatggatggtatattagcagaagacttgacgctagatttgagagat
atacagagaccagattcagagcatggtttttctcctgattcagagaactttgattggaaa
gctattcaagaaggtgcaaattctatagtgagtagtttacaccaagctgctgctgctgct
tgtttgtctagacaggcttcatctgattctgattccattctttcactcaagtcaggaatt
tctcttggatcaccatttcatcttacacctgatcaagaggagaaaccctttacaagtaat
aaagggccacgaatcctaaagcctggggagaagagtacattggagacgaaaaaaatagaa
tctgaaaataaaggcatcaaaggaggaaagaaagtttataaaagtttgatcactggaaaa
gttcgttctaattctgaagtttctggccagttgaaacaacccctaccgacaaatatgcct
tcaatttctcgaggaaggacaatgattcacattccaggcatccgaaacagctcctcaagt
acaagtccagtctccaaaaagggcccatccctcaaaaccccaacttccaaaagccccagt
gaggggccaacttccagtacttctcctagaggagctaagccatcagtcaaatccgaatta
agtccggtgaccaggcagacatcccaaccaggtggttcaagtaaaggaccttctagatca
ggatctagagattcaactccttcaagaccgtctcagcaaccattaagtagacctatgcag
tctccgggacgaaactctatttctcctggtagaaatggaataagtcctcctaacaaattg
tctcaactgccacggacttcatcccccagtacttcctcaactaaatcctcaggttctggg
aaaatatcatatacatctccaggaagacagatgagccagcaaaaccttactaaacaaaca
ggtttatctaagaataccagtaatatacccagaagcgagtctgcgtctaaaggactaaat
cagataagtaacagtaatggaactaataaaaaagttgaactttctaggatgtcttccacc
aagtctagtggaagtgaatccgacagatcagaaagacctgttttagtgcgccagtcaact
ttcatcaaagaaaccccaagcccaacgctaaggagaaaattggaagagtctgcctccctt
gaatctttgtcttcatcttctaggccagattctcctaccaaatcccaggtacagactcca
attttaagtccatcccttcctgatatgtctttgtccacccattcatccattcagactgga
agctggcgaaaactcccacctaatctgaatccttctatagagtttaatgatggaagatca
acaaagcgccatgatatagcacgttcccattctgagagcccttctagacttccagttaat
aggtcaggaacttggaagcgtgagcacagtaagcattcatcatcacttcctcgtgtaagc
acttggagaagaactggaagttcctcctctattctctctgcttcatcagaatccagtgaa
aaagcaaaaagtgaagatgaaaaacatgtaagttcacttctgggcacaaagcaaactaaa
gaaaaccaaggaccagcaaaaggaacttggagaaaaataaaagaaagtgaaatgactccc
ataagtaatgtttcccaggttacttcctcaggtactaccaatggtgctgattcaaagact
ttaatttatcaaatggcgcctgctgtctccaagacagaagatgtgtgggtaagaattgag
gattgccccattaataaccctagatcaggaagatcccctactggaaatacacccccagtg
atcgataacgttgcggagaaggtcagttctgggaataaagagtcaaaagataatcaggga
aaacccaacgggggcaacggcagcagtgctcctgctcgcactgttggcttagaaaaccgt
ctgaattccttcatacagatagatagcccagataaaaaggctgctgaaacaaaatcagga
caagtcaatcttgtccctgcaccagagaccagtgagacttccgttgccgagcgtacaccg
ttcagttccactagctcgagcaagcacagttcccctagtggaactgttgctgccagggtg
actcctttcaattacaatccaagtcctaggaagagcagtgcagatagcagtgcagcccgc
ccatcgcagatccctaccccagtaaataacagcacaaaaaagagagattcaaagacggaa
aacacagaatccagtggaactcaaagccctaagcgccattctgggtcttacttggtaacg
tctgtttaa

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