Monodelphis domestica (gray short-tailed opossum): 100014379
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Entry
100014379 CDS
T01031
Symbol
GCLC
Name
(RefSeq) glutamate-cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
mdo
Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo00270
Cysteine and methionine metabolism
mdo00480
Glutathione metabolism
mdo01100
Metabolic pathways
mdo01240
Biosynthesis of cofactors
mdo04216
Ferroptosis
Module
mdo_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
mdo00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
100014379 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
100014379 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
100014379 (GCLC)
Enzymes [BR:
mdo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
100014379 (GCLC)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
100014379
NCBI-ProteinID:
XP_001364496
Ensembl:
ENSMODG00000018800
UniProt:
A0A5F8HLU9
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Position
2:complement(302214802..302285539)
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AA seq
637 aa
AA seq
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MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKERHKDVLKWGDEVEYMLVSFDH
QNKKARVVLNGEEILEALQEKGERKNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRQEASSLLKENEALCTITSFPRLGCPGFTVPDYKPTPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPFPFIETFPQDDEATQAAQPNHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSASSPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNSYRISKSRYDSIDSYLSKCGEKYNDIDLTKDKEIYERLLK
EGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
HGLFYFRKDICKGGTAVVDGCSTAQNGTETDTEEFTLMSIDTIINGKEGAFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTAARWMREFVSKHPDYKQDSVITDEINYS
LLWECNKIANELSECPELLGSGFKKAKYSGNKTGSSS
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atgggactcctgtcccagggctctccgcttagctgggaagagaccaagcgccacgcggac
catgtgcgccggcacgggatcctccagtttctgcatatttaccacgccgtcaaggagcgg
cacaaagacgtcctcaagtggggcgatgaggtggaatacatgttggtgtcttttgaccac
cagaataaaaaagcacgcgtggttctgaacggagaggaaatcctagaagcattgcaagaa
aaaggagaaaggaaaaacccaaaccatccaacactttggagaccagaatatggaagctat
atgattgaagggacaccaggacaaccatatggaggaacaatgtcagaatttaacacagtt
gaagacaacatgagaaaacgtaggcaggaggcttcgtctcttttaaaagaaaatgaggct
ttatgcactataacatcatttcccagattaggctgtcctggcttcacagtacctgactac
aaacctacacccgttgaaggaggagcttcaaagtccctgttctttccagatgaggcaata
aacaaacaccccagattcagtaccttaacaaggaatatccgacataggagaggagaaaaa
gttgttatcaatgtaccgatctttaaggacaagaatactccatttccatttatagaaacg
tttcctcaggatgatgaagccactcaagcagctcaaccaaatcatatttatatggatgct
atgggatttggaatgggcaattgctgccttcaggtgacattccaggcttgcagtatatca
gaagccagatacctttatgatcagctggctactatttgtccaattgtaatggctttgagt
gcttcgtctcctttctaccgaggctatgtgtcagatattgattgtcgctggggagtaata
tctgcctcggtagatgatagaacccgggaggagagaggattggagcctctgaagaacaac
agctataggattagcaaatcccgatatgattcaatagacagttatttgtccaaatgtggt
gaaaaatacaatgatattgacttgacaaaagataaagaaatctatgaacgcctattaaag
gaagggatcgaccatctcctggcccagcatattgcccatctcttcattcgggaccccctg
acgttgttcgaagagaagatacacctagacgatgccaatgagtctgaccattttgagaat
attcagtctacaaattggcagaccatgagatttaaacctcctcctccaaattcggatatt
ggatggagggtagaatttcggcccatggaggttcaattaacagactttgagaactctgcc
tatgtggtatttgtggtcctgctaaccagagtgatcctttcgtacaaactggattttctc
attcccctgtcaaaggttgatgaaaacatgaaagtggctcagaaacgagacgctgtctta
catggactcttttatttccggaaagatatttgcaaaggtggcactgctgtagtggatggc
tgtagtacagcccagaatggtacagagacagacaccgaagaattcactttaatgagcata
gatacaatcatcaacgggaaggaaggtgcctttcctggcctgataccaattctaaactct
tacttggaaaatatggaagtggatgtagacacaagatgcagcatacttaattacttgaag
ttaattaagaaaagagcatcaggagaactgatgacagctgcacgatggatgagggagttt
gtttcgaagcaccccgactacaagcaagacagtgtcatcactgatgaaatcaattatagc
cttctttgggaatgtaacaagattgcaaatgaattaagcgaatgcccagagctgcttggc
tcaggatttaagaaagcaaaatatagtggaaataaaacgggctcttccagttaa
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