Monodelphis domestica (gray short-tailed opossum): 100016027
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Entry
100016027 CDS
T01031
Symbol
TOP2A
Name
(RefSeq) topoisomerase (DNA) II alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
mdo
Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
mdo00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100016027 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
mdo03032
]
100016027 (TOP2A)
03036 Chromosome and associated proteins [BR:
mdo03036
]
100016027 (TOP2A)
Enzymes [BR:
mdo01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
100016027 (TOP2A)
DNA replication proteins [BR:
mdo03032
]
Eukaryotic type
DNA Topoisomerases
100016027 (TOP2A)
Chromosome and associated proteins [BR:
mdo03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
100016027 (TOP2A)
Centrosome formation proteins
Centriole proteins
100016027 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
ComGE
Motif
Other DBs
NCBI-GeneID:
100016027
NCBI-ProteinID:
XP_007482328
Ensembl:
ENSMODG00000013152
UniProt:
F7ABY1
LinkDB
All DBs
Position
2:197115933..197146924
Genome browser
AA seq
1557 aa
AA seq
DB search
MEDLSPLQPVNENLQINKIKKNEDTKKRLSVERIYQKKTQLEHILLRPDTYIGSVEVVTQ
QMWVYDEEVGLNYRDVTFVPGLYKIFDEILVNAADNKQRDPKMNCIKVTIDSENNTISIW
NNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTV
ETACKEYKKMFKQTWMDNMGKAGEMTLKPFSGEDYTCITFQPDLSKFKMTSLDKDMVALM
SRRAYDIAGSTKDVKVFLNGNRLPVKGFRSYVDLYVKDKLDETGNPLKIIHEEVNHRWEV
CLTMSEKGFQQISFVNSIATSKGGRHVDYVADQIISRLIDVVKKKNKGGVAVKAHQVKNH
MWIFVNALIENPTFDSQTKENMTLQAKNFGSKCELSEKFIKAAIGCGIVESILNWVKFKA
QVQLNKKCSAVKHNRIKGIPKLDDANDAGSKNSTDCTLILTEGDSAKTLAVSGLGVVGRD
KYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDADSLKSLRYGKIMIM
TDQDQDGSHIKGLLINFIHHNWPSLLKHCFLEEFITPIVKVSRNKQEMSFYSLPEFEEWK
NTTENHKKWKVKYYKGLGTSTSKEAKEYFSDMSRHRIQFKYSGPEDDAAISLAFSKKQID
DRKEWLTHFMEDRRQRKLLGLPEDYLYGKATKHLTYNDFINKELILFSNSDNERSIPSMV
DGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSN
NLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPAKDDQTLKFLYDDNQRVEPE
WYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGTI
DELAPNQYVISGEVSIINSTTIEISELPVRTWTQVYKEQVLEPMLNGTDKTPPLITDYRE
YHTDTTVKFIVKMTEEKLAQAEHAGLHKVFKLQTNLTCNSMVLFDHVGCLKKYDTALDIL
RDFFDLRLKYYGLRKEWLTGMLGAESAKLNNQARFILEKIEGKIVIENKPKKELIKVLIQ
RGYDSDPVKAWKEAQQKSPGDNEEETEESDNEKETEKSDSATDSGPTFNYLLDMPLWYLT
KEKKDELCRQRTEKEQELENLKRKSPSDLWKEDLAAFVEELEVVEAKEKRDEQVGTIGKG
KAGGKPKAKKGQVAETLPSPHGRRVVPRVTVEMKAEAEKKIRKKIKTENIEGSPQEDSLD
PETLKQRLDKKLKTESGPKQKKQSKLPFKPIKKENKRNPWSDSESDLSCDESEFYAPPRE
TKSRRAVAANKKYTVDLDSDTDISDSKEEFQDEEDEDFIPSDGSSSKVKSVPKATKGQTT
SKVQEPPKSSPSHEGEDLEPEDTKDMALASSSSSTLDFPVELEIPDPVPKKSTAVKKTAA
KSQSSTSVTATKKRAAPKTSKKTSKTSLDSVSETSEKTVAAKSKKPRKRKPSNSDDSDSD
FGKGKSTAKAVKKSKMVDDDFQIDSNSSSTPVAPRARPGRAKKPIKYLEESDEDDMF
NT seq
4674 nt
NT seq
+upstream
nt +downstream
nt
atggaggacctgtcgccattgcagcctgtaaatgaaaatctacaaattaataaaataaag
aaaaatgaagacacgaagaaaagattgtctgttgagagaatctatcaaaagaaaacccaa
ttggagcatattttgctccgacctgatacctatattggctctgtagaggttgtgactcag
caaatgtgggtttatgatgaagaagttggacttaactacagagatgtgacttttgttcct
ggtttgtacaaaatttttgatgaaattttagtgaatgctgccgacaacaagcagagggac
ccaaaaatgaactgtattaaagtcacaatagattcggaaaacaatacaattagtatatgg
aataatgggaaaggtattcctgttgtagagcataaggttgagaaggtctatgtgccagct
cttatctttggacagctcttgacttccagtaactatgatgatgatgagaagaaggttacc
ggtggtcgaaatggatatggagccaaattatgcaatatattcagtaccaagtttacagtg
gaaactgcctgtaaagaatataagaaaatgtttaagcagacctggatggataacatgggg
aaagcaggtgaaatgactctcaagccctttagtggagaagactatacatgtattaccttc
caacctgatctatctaagtttaaaatgacatctctagacaaggatatggttgctttgatg
tctagaagagcatatgatattgctggttccaccaaagatgtcaaggtctttctcaatgga
aataggctgcctgtaaaaggattccgtagctatgtggatttgtatgtgaaggacaaattg
gatgaaactggcaacccactgaaaattatacatgaagaagtaaaccacaggtgggaagta
tgtttaactatgagtgaaaaaggcttccagcaaattagctttgtcaacagcattgccact
tccaagggtggcagacatgttgattatgtagctgatcaaattataagtagacttattgat
gttgtgaagaaaaagaacaaagggggtgttgcagtaaaagcacatcaggtgaagaaccac
atgtggatttttgtgaatgccttaattgaaaacccaacctttgactcccagactaaggaa
aatatgactctacaggccaagaactttggttcaaaatgtgaattgagtgaaaaattcatc
aaagctgcaattggttgtggaattgtagaaagcatactaaactgggtgaaatttaaggcc
caagtccagttgaataaaaagtgttcagctgttaaacataatagaatcaagggaattcct
aaacttgatgatgctaatgatgcaggcagtaagaactctacagattgtacacttatcttg
actgagggagactcagccaaaactttagctgtttctggccttggtgtggttggaagagac
aagtatggcgttttcccccttcgaggaaaaatactcaacgttcgagaagcctctcataaa
caaatcatggaaaatgctgaaattaataatatcattaagattgtgggtcttcaatacaag
aaaaactatgaagatgcagattcattaaagagcctccgttatggaaaaatcatgattatg
acagatcaggatcaagatggttcccacatcaaaggcttgttgattaatttcatccatcac
aattggccctctcttctgaaacattgttttctggaggaatttatcacccctattgtaaag
gtctcaagaaataaacaggaaatgtcattttatagccttcctgaatttgaagaatggaaa
aatactactgaaaatcacaaaaaatggaaagtcaagtattacaaaggtttgggcaccagt
acatcaaaagaagcaaaggaatacttttcggatatgtcaagacatcgaatccaattcaaa
tattctggccctgaagatgatgctgctatcagcctggcctttagcaaaaagcagattgat
gatcgaaaagaatggctaacacatttcatggaagatagaagacagcggaagttacttggc
ctccctgaggattacttatatgggaaagctactaagcatctaacatataatgactttata
aataaagaactcatcttattctcaaactctgataatgagaggtctatcccatcaatggtg
gatggtttgaagccgggtcagagaaaagtcctattcacatgtttcaaaagaaatgacaag
agagaagtgaaggttgcccaattagctggttcagtagctgagatgtcctcttatcatcat
ggtgaaatgtcactaatgatgaccattatcaatttggctcaaaattttgtgggcagcaac
aatctcaacctcttgcagcccattggtcagtttggtaccaggctgcatggtggcaaggac
tctgccagccctcgatacatcttcacaatgctcagcccattggctcggttacttttccca
gcaaaggatgatcagactctgaagtttttatatgatgacaaccagcgtgtagagccagag
tggtacattcctattattcccatggtattgataaatggtgcagaagggattggaactggc
tggtcctgcaagatccccaactttgatgtccgagaagttgtgaataatattagacgcctg
atggatggagaagaacctttaccaatgctacctagctacaaaaatttcaagggtacaatt
gatgagctggctccaaatcaatatgttatcagtggtgaagtgtctattataaattcaaca
accattgaaatctctgaacttccggtcagaacttggacccaggtttataaagaacaggtt
ctggagcccatgttgaatggcaccgacaagacacctcccctcataacagactacagggaa
taccacactgataccacagtgaagttcatagtcaagatgactgaagagaaactagcccaa
gcagagcatgcaggactgcacaaagtcttcaaacttcagactaatctaacatgtaattct
atggtactttttgatcatgttggctgtctaaagaagtatgatactgcattggatatccta
agagatttctttgatctgaggcttaaatattatggactgagaaaagaatggcttacagga
atgcttggtgctgaatctgccaaattgaacaaccaggctcggttcatcctagagaagata
gaggggaaaatagtcattgaaaataagcctaagaaggagttaattaaggttctgatccaa
aggggatatgattcagatcctgtcaaggcctggaaggaagctcagcaaaagagtcctggc
gacaatgaagaggaaactgaagaaagtgacaatgaaaaagaaactgaaaaaagtgactca
gccactgattctggaccgacttttaactatcttcttgatatgcctctttggtatttgacc
aaggaaaagaaagatgaactctgcaggcagagaactgaaaaagagcaagaactggagaac
ttaaagcgaaaaagtccttcagatttatggaaagaagacttggctgcttttgttgaagaa
cttgaagttgttgaagccaaggaaaaacgggatgaacaagtgggtactattggtaaaggt
aaagccggtgggaaaccaaaggcaaagaaaggtcaagtggcagaaactttgccctctcct
catggcagacgagttgtccctcgggttactgtagaaatgaaagcagaagcagaaaagaaa
atcagaaagaaaattaagactgaaaatattgagggaagtcctcaagaagacagtctagat
ccagaaactctaaaacaaagactagacaaaaagctcaagacagaatcaggtcccaagcaa
aagaagcagagcaaattgccattcaaaccaatcaaaaaagaaaataagagaaatccttgg
tctgattcagaatctgatttgagttgtgatgaaagtgaattttatgcccctcctagagaa
actaaatcacgcagggcagtagcagcaaataagaaatacacagttgatttagattccgac
acagatatttcggattctaaagaggaatttcaagatgaagaagatgaggattttatccca
tcagatggaagttcatctaaggttaaaagtgtaccaaaagcaactaaaggacaaactact
agcaaagtacaggagccaccaaaaagttctccatcacatgaaggtgaggacctggaacct
gaagatactaaggatatggctctagcttcttcaagctcttctactttagattttccagtt
gaacttgaaattccagatccagttcccaaaaaaagtactgcagtgaaaaagactgcagca
aagagtcagtcttctacttcagttactgcaacaaagaagagggcagcaccaaaaacaagt
aaaaagacctccaaaacttctctagattctgtctctgaaacctctgaaaagactgtggca
gccaaaagcaagaaacctcgcaaaaggaagccttctaactctgatgactctgattcagat
tttggaaaaggcaaatcaacagccaaggcagtgaagaaatccaaaatggtggatgatgac
ttccagattgattcaaattcaagctcaactcctgtggcaccccgggcaagacctggccga
gcaaagaagcctattaaatacctggaagaatcagatgaggatgatatgttttaa
DBGET
integrated database retrieval system
