Monodelphis domestica (gray short-tailed opossum): 100017615
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Entry
100017615 CDS
T01031
Symbol
ARAF
Name
(RefSeq) A-Raf proto-oncogene, serine/threonine kinase
KO
K08845
A-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
mdo
Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo01521
EGFR tyrosine kinase inhibitor resistance
mdo01522
Endocrine resistance
mdo04010
MAPK signaling pathway
mdo04012
ErbB signaling pathway
mdo04068
FoxO signaling pathway
mdo04270
Vascular smooth muscle contraction
mdo04650
Natural killer cell mediated cytotoxicity
mdo04720
Long-term potentiation
mdo04726
Serotonergic synapse
mdo04730
Long-term depression
mdo04810
Regulation of actin cytoskeleton
mdo04910
Insulin signaling pathway
mdo04914
Progesterone-mediated oocyte maturation
mdo04928
Parathyroid hormone synthesis, secretion and action
mdo05010
Alzheimer disease
mdo05022
Pathways of neurodegeneration - multiple diseases
mdo05034
Alcoholism
mdo05160
Hepatitis C
mdo05161
Hepatitis B
mdo05200
Pathways in cancer
mdo05205
Proteoglycans in cancer
mdo05208
Chemical carcinogenesis - reactive oxygen species
mdo05210
Colorectal cancer
mdo05211
Renal cell carcinoma
mdo05212
Pancreatic cancer
mdo05213
Endometrial cancer
mdo05214
Glioma
mdo05215
Prostate cancer
mdo05218
Melanoma
mdo05219
Bladder cancer
mdo05220
Chronic myeloid leukemia
mdo05221
Acute myeloid leukemia
mdo05223
Non-small cell lung cancer
mdo05224
Breast cancer
mdo05225
Hepatocellular carcinoma
mdo05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
mdo00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
100017615 (ARAF)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100017615 (ARAF)
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
100017615 (ARAF)
09156 Nervous system
04726 Serotonergic synapse
100017615 (ARAF)
04720 Long-term potentiation
100017615 (ARAF)
04730 Long-term depression
100017615 (ARAF)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100017615 (ARAF)
05205 Proteoglycans in cancer
100017615 (ARAF)
05208 Chemical carcinogenesis - reactive oxygen species
100017615 (ARAF)
09162 Cancer: specific types
05210 Colorectal cancer
100017615 (ARAF)
05212 Pancreatic cancer
100017615 (ARAF)
05225 Hepatocellular carcinoma
100017615 (ARAF)
05226 Gastric cancer
100017615 (ARAF)
05214 Glioma
100017615 (ARAF)
05221 Acute myeloid leukemia
100017615 (ARAF)
05220 Chronic myeloid leukemia
100017615 (ARAF)
05218 Melanoma
100017615 (ARAF)
05211 Renal cell carcinoma
100017615 (ARAF)
05219 Bladder cancer
100017615 (ARAF)
05215 Prostate cancer
100017615 (ARAF)
05213 Endometrial cancer
100017615 (ARAF)
05224 Breast cancer
100017615 (ARAF)
05223 Non-small cell lung cancer
100017615 (ARAF)
09172 Infectious disease: viral
05161 Hepatitis B
100017615 (ARAF)
05160 Hepatitis C
100017615 (ARAF)
09164 Neurodegenerative disease
05010 Alzheimer disease
100017615 (ARAF)
05022 Pathways of neurodegeneration - multiple diseases
100017615 (ARAF)
09165 Substance dependence
05034 Alcoholism
100017615 (ARAF)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100017615 (ARAF)
01522 Endocrine resistance
100017615 (ARAF)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mdo01001
]
100017615 (ARAF)
Enzymes [BR:
mdo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100017615 (ARAF)
Protein kinases [BR:
mdo01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
100017615 (ARAF)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
zf-RING-like
TUG-UBL1
Viral_DNA_bp
C1_2
Motif
Other DBs
NCBI-GeneID:
100017615
NCBI-ProteinID:
XP_016282056
Ensembl:
ENSMODG00000010855
LinkDB
All DBs
Position
X:71693051..71697598
Genome browser
AA seq
467 aa
AA seq
DB search
MSRGPAATPVEAFSRGLAPPGDPSATPSTSARVGGTVKVYLPNQQRTVVTARDGMTVSDS
LDKALKVRGLNQDCCAVYRLVQGRKTATAWDAAIAPLHGEELTVEVRADVPLAAAHNFAR
KTFLALTFCDFCRRFLFHGFRCQTCGYKFHQHCSARVPTICVDMATARQPFYRSIQDLAG
GPRAHEVQPDNQALCEPLTPKSPSTQAQTSHGGEAFAFPGPGGPALQRIRSTSTPNVHMI
STTMPVDSRLIQQAAQAFQATEGTGGERIPQSSPGLVSPPGKKSPHPKASAEPTERKAPA
LADDKKKVKSLGYRDSGYYWEVAPGEVQLLKRIGTGSFGTVFHGRWHGDVAVKVLKVAQP
TAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPDFAIITQWCEGSSLYHHLHVADTHFDM
VQLIDVARQTAQGMDYLHAKNIIHRDLKSNSIHLACVCVWGGGGGKG
NT seq
1404 nt
NT seq
+upstream
nt +downstream
nt
atgagtcgaggcccagcagccaccccagtggaagccttcagcaggggtttagccccacct
ggagatcccagtgccaccccttctaccagtgctcgggttgggggcactgtgaaggtctat
ttgcccaaccaacagcgcactgtggtgactgcacgggatgggatgactgtctccgactca
ttggacaaggcactgaaggttcgggggctgaatcaggattgctgtgctgtctatcgcttg
gtacagggccggaagacagcaacagcctgggatgctgccatcgctcccttgcatggggaa
gaattgactgtggaggtccgggctgatgtcccccttgcggcagcccacaacttcgcccgg
aagacgtttctggctcttaccttctgtgacttctgccgccgcttcctctttcatggattc
cgctgccagacatgtggctacaagtttcaccaacactgcagtgcccgagtccccaccatc
tgtgtcgacatggctactgcccgccaacctttctaccgcagtatccaggatttggctgga
gggccccgtgctcatgaggttcaaccagacaaccaggccctctgtgagcctctcactcca
aagagccccagtacccaagcccagacctcccatgggggggaagcctttgctttccctggg
cctggaggcccagccttacagaggatccgttctacatccacacctaatgtgcacatgatc
agcaccacgatgcctgtggacagcaggctcatccagcaggcagcccaggccttccaggct
actgaaggaacaggtggtgagaggatccctcaaagcagtcctggccttgtttcccctcct
ggaaagaaatccccacaccccaaggcttcagcagagcccactgagcgcaaagccccagcc
ttggctgatgacaagaagaaagtgaagtccctgggctaccgagactcaggctactattgg
gaggtggcaccaggggaggtacagctgctgaagaggatcgggacaggctcatttgggacc
gtgttccatgggcgctggcacggggacgtggcggtgaaggtgctaaaggtggcgcagccc
actgctgagcaagcccaggccttcaaaaatgagatgcaagtcctcaggaagactcgccac
gtcaacatcctcttgttcatgggtttcatgacgaggcctgactttgccatcatcacccag
tggtgcgagggctccagcctctaccaccacctccatgtggctgatactcactttgacatg
gtgcagctgattgatgtggctcggcagacagctcagggcatggattacctccacgccaag
aacatcattcaccgagatctcaaatccaacagtatccacctagcctgtgtgtgtgtgtgg
gggggggggggggggaagggatga
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