Monodelphis domestica (gray short-tailed opossum): 100018035
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Entry
100018035 CDS
T01031
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase 3
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
mdo
Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo00220
Arginine biosynthesis
mdo00330
Arginine and proline metabolism
mdo01100
Metabolic pathways
mdo04020
Calcium signaling pathway
mdo04022
cGMP-PKG signaling pathway
mdo04066
HIF-1 signaling pathway
mdo04071
Sphingolipid signaling pathway
mdo04151
PI3K-Akt signaling pathway
mdo04370
VEGF signaling pathway
mdo04371
Apelin signaling pathway
mdo04611
Platelet activation
mdo04915
Estrogen signaling pathway
mdo04921
Oxytocin signaling pathway
mdo04926
Relaxin signaling pathway
mdo04931
Insulin resistance
mdo04933
AGE-RAGE signaling pathway in diabetic complications
mdo05415
Diabetic cardiomyopathy
mdo05417
Lipid and atherosclerosis
mdo05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mdo00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
100018035 (NOS3)
00330 Arginine and proline metabolism
100018035 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
100018035 (NOS3)
04371 Apelin signaling pathway
100018035 (NOS3)
04066 HIF-1 signaling pathway
100018035 (NOS3)
04020 Calcium signaling pathway
100018035 (NOS3)
04071 Sphingolipid signaling pathway
100018035 (NOS3)
04022 cGMP-PKG signaling pathway
100018035 (NOS3)
04151 PI3K-Akt signaling pathway
100018035 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100018035 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
100018035 (NOS3)
04921 Oxytocin signaling pathway
100018035 (NOS3)
04926 Relaxin signaling pathway
100018035 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100018035 (NOS3)
05418 Fluid shear stress and atherosclerosis
100018035 (NOS3)
05415 Diabetic cardiomyopathy
100018035 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
100018035 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
100018035 (NOS3)
Enzymes [BR:
mdo01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
100018035 (NOS3)
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Gene cluster
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
100018035
NCBI-ProteinID:
XP_001371412
Ensembl:
ENSMODG00000003903
UniProt:
F6S3S1
LinkDB
All DBs
Position
8:215557007..215581627
Genome browser
AA seq
1193 aa
AA seq
DB search
MGNLKSVGQEPGPPCGLGLGLGLGLCSKQSGTPGPENGGPPVADISPPVARPPEGPKFSR
IKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVSPRQLQSRPTEGPPSPGQLLIQARDF
INQYYSSIKRSGSPAHGQRLGEVEAEVAATGTYQLRESELVFGAKQAWRNAPRCVGRIQW
GKLQVFDARDCSSAQEMFTYICNHIKYATNKGNLRSAITVFPQRSPGKGDFRIWNSQLIR
YAGYRQQDGSVLGDPANVEITELCIQHGWTPGDGRFDVLPLLLQASDEPPELFPLPPELV
LEVPLQHPTLEWFESLGLRWYALPAVSNMLLEIGGLEFPAVPFSGWYMSSEIGMRNLCDP
HRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIVDHHAATASFMKH
LENEQRARGGCPADWVWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWKGTTTKGTGI
TRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRLFRKAFDPRV
LCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGERFAAALMEMSGPYNSSPRPEQHKSYK
IRFNSVSCSDTLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFCAFARAVDTR
LEELGGERLLQLGQGDELCGQEEAFQGWAQAAFRASCETFCVGDDAKAAARDIFSPKRSW
KRQRYRLSAQPEGLQLLPGLIHVHRRKMFPATVLSVENLQSSKSTRATILVRLATGGQEG
LQYQPGDHIGICPPNRPGLVEALLSRVEDPPLPSEPIAVEQLEKGSPGGPPPGWVRDPRL
PSCTLQQALTFFLDITSPPGPQLLRLLSTLAEEASEQQELEALSKDARRYEEWKWFRCPT
LLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSAHPGEIHLTVAVLAYRTQDGLGP
LHYGVCSSWLSQLKAGDIVPCFIRGAPSFRLPSDPNVPCILVGPGTGIAPFRGFWQERLH
DIENKGLHPAPMTLVFGCRCSQLDHLYREEVQDAQHRGVFGRVLTAFSRELDSPKTYVQD
ILRTELASEVHRVLCREGGHMFVCGDVTMATSVLQTVQRILATEGGMELSEAGDVIGVLR
DQQRYHEDIFGLTLRTQEVTNRIRTQSFSLQERQARSAVPWALSEPTPETPES
NT seq
3582 nt
NT seq
+upstream
nt +downstream
nt
atgggcaatttgaagagtgtgggtcaggagcctggcccgccctgtggactgggcttgggg
ctggggctgggattatgcagcaaacagagcgggactccaggacctgagaacggggggcca
ccggtggctgacatcagcccccctgtggcccggccacctgaaggacccaaattctcaaga
ataaagaactgggaagtaggaagcatcacctatgacacactgagtgcccaagcccaacag
gatggaccctgtactccacggagatgcctgggctcccttgtgtctccaaggcaacttcaa
agtcgccccacggaggggcccccatctcctggccagctactgatccaggctcgagatttc
attaaccaatactacagttctatcaagaggagtggctccccagcccatggacaacggctt
ggggaagtggaggctgaggtggcagccacaggcacctaccaactcagggagagtgagctt
gtgtttggggctaagcaggcctggagaaatgcccctcgatgtgtgggcaggatacagtgg
gggaagctacaggtatttgatgcccgagactgcagctctgctcaggagatgttcacctat
atttgcaatcacatcaagtatgccaccaacaaaggcaaccttcgctcagccatcacagtg
tttccccagcgctccccaggcaagggggacttccgtatctggaatagtcagttgatccga
tatgcaggctacagacaacaagatggctctgtcttgggggacccggccaatgtggagatc
actgagctctgcatccagcatggctggaccccaggggatggacgcttcgatgtgctgcca
ctgctgctccaggcctcagatgagccacctgaacttttccctctgcccccagaacttgtg
ctggaggtgccactacaacatcctacgctggagtggtttgagtccttgggtctccgttgg
tatgcactcccggccgtgtccaacatgctgctggaaattggaggcctggaattccctgca
gttcccttcagtggatggtacatgagcagtgagattggcatgcgcaacctgtgtgacccc
caccgctacaacattcttgaggatgtggctgtctgcatggacctggacacccggacaacc
tcgtctctgtggaaggacaaggcagctgtggagatcaacctagcagtgctacatagctac
caactggccaaagtgaccattgtggatcaccatgcagccacagcctctttcatgaagcat
ctggagaatgagcagagggcacgaggtggctgccccgctgactgggtctggattgtgcct
ccaatctctggcagtcttactccagtctttcaccaagagatggtcaactacttcttgtca
cctgccttccgctatcagcctgacccatggaaggggacgacaacaaaaggcactggcatc
accaggaaaaaaacctttaaggaagtggccaatgcagtgaagatttcagcttccctgatg
ggcacagtgatggcaaagcgggtgaaggcaacgattctgtatggctcagaaactggtcgg
gcccagagctatgcccagcagctgggcaggttgttccggaaagccttcgaccctcgggtc
ctttgcatggatgaatatgatgtggtgtccctggagcatgagacccttgtcctggtggta
accagcacatttggaaatggagatcctccagaaaatggagagaggtttgcagctgccttg
atggaaatgtctggcccctacaatagctctcccagaccagagcagcacaaaagctacaag
attcgtttcaacagcgtctcctgctcagacacgttggtatcttcttggagacggaagagg
aaagagtccagtaacacggacagtgcaggggccctaggaaccctaaggttctgtgtattt
gggcttggctcccgggcgtacccccatttctgtgcttttgcccgagcagtagacacacga
ctggaagaactgggaggagagaggctactgcagctgggccagggggatgaattatgtggc
caggaagaggctttccagggctgggcccaagctgcattccgggcctcctgcgagaccttc
tgtgtgggggacgatgccaaggctgctgcccgggatatattcagtcccaagagaagttgg
aagcgccaaagataccgcctgagtgcccagcctgaggggctccagctgctacccggcctg
atccacgtgcacaggcggaagatgttcccagccactgtcctctcagtggaaaacctgcag
agcagcaagtcgacccgagccacaatcctggtgcgtctggccacaggagggcaggaaggc
ctacagtatcagcctggagaccacattggaatctgccctcccaaccgacctggcttggtg
gaagccctgttgagccgtgtggaggatccacccctgcccagtgagcctatcgctgtggag
cagctggagaaggggagcccaggtggcccacccccaggttgggttcgggacccccggctg
ccttcatgcacattacaacaggctctcaccttctttctggatatcacctcccccccaggg
cctcagctccttcgactactcagcaccctggcagaggaggccagtgagcagcaagagctg
gaggccctcagcaaggatgctcggcgctatgaggaatggaaatggttccgttgtcctaca
cttctggaggtgctagagcagttcccatcagtggcactgccagcacctctcctcctcacc
caactgcctttgctccagccacggtactactcggtcagctctgcacccagtgcccaccct
ggggagatacacctcacagtggctgtgctggcctataggacacaggatgggctaggcccc
ttgcactatggggtctgctcctcatggttaagccagctcaaggctggagacatagtgccc
tgcttcatcagaggggctccatctttccggcttccatctgaccctaacgtcccctgtatc
cttgtggggcccggtacaggcatcgcccctttccgcggattctggcaggagcggctacat
gacattgagaacaaaggactgcatccggcccctatgaccctggtcttcggatgccgctgc
tcccagcttgaccacctttaccgagaggaggtgcaggatgcccagcatcggggagtcttt
ggcagagtccttacagccttttccagggaactggatagccccaagacctatgtgcaggac
atccttcggactgagctagcctccgaggtgcaccgcgtgctgtgccgggagggcggccac
atgttcgtctgcggagacgtcactatggcgaccagcgtcctgcagacggtgcagcgaatc
ctggccacggagggtgggatggagctgagtgaggccggagatgtcattggggtgctgcgg
gaccagcaacgctaccatgaggacatcttcgggctgacgctacggacgcaggaagtgacg
aaccgcattcgtacgcagagtttctcgctgcaggagcggcaagcgcggagcgccgtgccc
tgggccctcagcgagcccaccccggagacccccgagtcctga
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