Monodelphis domestica (gray short-tailed opossum): 100022269
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Entry
100022269 CDS
T01031
Symbol
PKLR
Name
(RefSeq) pyruvate kinase, liver and RBC
KO
K12406
pyruvate kinase isozymes R/L [EC:
2.7.1.40
]
Organism
mdo
Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo00010
Glycolysis / Gluconeogenesis
mdo00620
Pyruvate metabolism
mdo01100
Metabolic pathways
mdo01200
Carbon metabolism
mdo01230
Biosynthesis of amino acids
mdo04910
Insulin signaling pathway
mdo04930
Type II diabetes mellitus
mdo04932
Non-alcoholic fatty liver disease
mdo04950
Maturity onset diabetes of the young
Module
mdo_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
mdo_M00002
Glycolysis, core module involving three-carbon compounds
Brite
KEGG Orthology (KO) [BR:
mdo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
100022269 (PKLR)
00620 Pyruvate metabolism
100022269 (PKLR)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
100022269 (PKLR)
09160 Human Diseases
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
100022269 (PKLR)
04950 Maturity onset diabetes of the young
100022269 (PKLR)
04932 Non-alcoholic fatty liver disease
100022269 (PKLR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mdo04147
]
100022269 (PKLR)
Enzymes [BR:
mdo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.40 pyruvate kinase
100022269 (PKLR)
Exosome [BR:
mdo04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
100022269 (PKLR)
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Gene cluster
GFIT
Motif
Pfam:
PK
PK_C
IMPDH
DACZ_N
HpcH_HpaI
Motif
Other DBs
NCBI-GeneID:
100022269
NCBI-ProteinID:
XP_001374169
Ensembl:
ENSMODG00000017053
UniProt:
K7E2Q6
LinkDB
All DBs
Position
2:complement(189975508..190027384)
Genome browser
AA seq
543 aa
AA seq
DB search
MEGQAGYLRRSSVAFLTQELGASFFQKQQLPAALADTFLEHLCLLDIDSEPVTARNTGII
ATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAAESFAASPITYRPV
AIALDTKGPEIRTGILQGGPEAEVKLEKGSEVRVTVNPEFRTLGNASTVWVDYPNIVQVV
QEGGFIYLDDGLISLVVKQKGQDELVTEVENGGILGSRKGVNLPGAEVDLPGLSEQDVQD
LRFGVEQGVDIVFASFIRKARDVIAIREALGLRGRGIKIVSKIENHEGVERFDEILEVSD
GIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMVTNARPTRAETSDV
ANAVLDGADCIMLSGETAKGKYPVEAVKMQHAIAREAEAAIFHRQLFEELRRAIPLSRDP
AEVTAIGAVEASFKCCAAAIIVLTTTGRSAQLISRYRPRAVVIAVTRFAQAARQAHLFRG
VFPLLYREPPAPIWSEDVDRRVQFGIENGKLRGFIRTGDLVIVVTGWRPGSGSTSIMRVL
SVS
NT seq
1632 nt
NT seq
+upstream
nt +downstream
nt
atggaggggcaagccgggtaccttcgaaggtctagtgtggcctttttgacccaggagcta
ggtgcttccttcttccagaagcaacagctcccagcagccctggcagatacctttctggag
catctctgcctactggacattgactcagaaccagtgactgcccgaaacaccggcatcatc
gctaccataggccccgcatctcgctctgtggatcggctgaaggaaatgatcaaagcagga
atgaatattgccaggctcaacttttcccatggctcccacgagtaccatgcggaatccata
gccaacgtgagagaggcggccgagagcttcgcggcgtcacccatcacctaccggcctgtg
gccatagcgctggacaccaaggggcccgagattcgcaccgggatcctccaggggggcccg
gaggcagaggtgaagctagagaagggttccgaggtccgggttacagtgaacccggaattc
cggactctggggaatgcaagcaccgtgtgggtggactatcccaacatagtccaggtagta
caggaagggggatttatctacctcgacgacgggcttatttctctggtggttaagcagaaa
ggccaagacgagctggttacggaggtcgagaatggcgggatcctgggaagcaggaaggga
gtgaacttgcctggtgcagaagtggacttgccgggattgtccgagcaggatgttcaggac
ctgcgcttcggagtggaacagggcgtggatattgtcttcgcatcctttatccgaaaggcc
cgtgatgtgattgctatacgagaagccctgggacttcggggaaggggaatcaagatagtc
agcaaaatagagaaccacgagggtgttgagaggtttgatgagatcctggaagtgagcgat
ggcatcatggtggctcgaggtgacctgggcattgagatcccagctgagaaagtcttcttg
gcacagaaaatgatgattggacgctgcaacttggctggcaagccagttgtctgtgccaca
cagatgctggaaagcatggtcaccaatgcccggccaactcgagcagaaacaagtgatgtg
gccaatgctgttctggatggggctgactgtatcatgttgtctggggagacagccaaggga
aagtaccctgtggaggctgtgaagatgcagcatgcgattgctcgggaagcagaggctgca
atctttcacaggcagctgtttgaagaacttcgtcgggcaatccccctaagtcgtgacccg
gctgaggtcactgccattggtgctgtggaggcttcattcaagtgctgtgctgctgctata
attgtgctgacaacgactggccgttcagctcaattgatctcccgataccgtccccgagca
gttgtcattgctgtcacacgttttgctcaggctgcccgccaggcccatctgtttcgtggt
gttttccccttgctctaccgtgaacccccagcgcccatctggtctgaagatgttgaccgt
cgtgtccaatttggcattgaaaatgggaagctccgtggttttatccgaactggggacctg
gtgattgtggtgacaggctggagacctggctcaggctctacaagcatcatgagagtcctg
agtgtatcctga
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