Monodelphis domestica (gray short-tailed opossum): 100027579
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Entry
100027579 CDS
T01031
Symbol
PLCG2
Name
(RefSeq) phospholipase C gamma 2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
mdo
Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo00562
Inositol phosphate metabolism
mdo01100
Metabolic pathways
mdo01521
EGFR tyrosine kinase inhibitor resistance
mdo04012
ErbB signaling pathway
mdo04014
Ras signaling pathway
mdo04020
Calcium signaling pathway
mdo04062
Chemokine signaling pathway
mdo04064
NF-kappa B signaling pathway
mdo04066
HIF-1 signaling pathway
mdo04070
Phosphatidylinositol signaling system
mdo04072
Phospholipase D signaling pathway
mdo04360
Axon guidance
mdo04370
VEGF signaling pathway
mdo04380
Osteoclast differentiation
mdo04611
Platelet activation
mdo04613
Neutrophil extracellular trap formation
mdo04625
C-type lectin receptor signaling pathway
mdo04650
Natural killer cell mediated cytotoxicity
mdo04662
B cell receptor signaling pathway
mdo04664
Fc epsilon RI signaling pathway
mdo04666
Fc gamma R-mediated phagocytosis
mdo04670
Leukocyte transendothelial migration
mdo04722
Neurotrophin signaling pathway
mdo04750
Inflammatory mediator regulation of TRP channels
mdo04919
Thyroid hormone signaling pathway
mdo04933
AGE-RAGE signaling pathway in diabetic complications
mdo04935
Growth hormone synthesis, secretion and action
mdo05167
Kaposi sarcoma-associated herpesvirus infection
mdo05169
Epstein-Barr virus infection
mdo05170
Human immunodeficiency virus 1 infection
mdo05171
Coronavirus disease - COVID-19
mdo05200
Pathways in cancer
mdo05205
Proteoglycans in cancer
mdo05206
MicroRNAs in cancer
mdo05214
Glioma
mdo05223
Non-small cell lung cancer
mdo05225
Hepatocellular carcinoma
Module
mdo_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
mdo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
100027579 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100027579 (PLCG2)
04014 Ras signaling pathway
100027579 (PLCG2)
04370 VEGF signaling pathway
100027579 (PLCG2)
04064 NF-kappa B signaling pathway
100027579 (PLCG2)
04066 HIF-1 signaling pathway
100027579 (PLCG2)
04020 Calcium signaling pathway
100027579 (PLCG2)
04070 Phosphatidylinositol signaling system
100027579 (PLCG2)
04072 Phospholipase D signaling pathway
100027579 (PLCG2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100027579 (PLCG2)
04613 Neutrophil extracellular trap formation
100027579 (PLCG2)
04625 C-type lectin receptor signaling pathway
100027579 (PLCG2)
04650 Natural killer cell mediated cytotoxicity
100027579 (PLCG2)
04662 B cell receptor signaling pathway
100027579 (PLCG2)
04664 Fc epsilon RI signaling pathway
100027579 (PLCG2)
04666 Fc gamma R-mediated phagocytosis
100027579 (PLCG2)
04670 Leukocyte transendothelial migration
100027579 (PLCG2)
04062 Chemokine signaling pathway
100027579 (PLCG2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
100027579 (PLCG2)
04919 Thyroid hormone signaling pathway
100027579 (PLCG2)
09156 Nervous system
04722 Neurotrophin signaling pathway
100027579 (PLCG2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
100027579 (PLCG2)
09158 Development and regeneration
04360 Axon guidance
100027579 (PLCG2)
04380 Osteoclast differentiation
100027579 (PLCG2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100027579 (PLCG2)
05206 MicroRNAs in cancer
100027579 (PLCG2)
05205 Proteoglycans in cancer
100027579 (PLCG2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100027579 (PLCG2)
05214 Glioma
100027579 (PLCG2)
05223 Non-small cell lung cancer
100027579 (PLCG2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
100027579 (PLCG2)
05171 Coronavirus disease - COVID-19
100027579 (PLCG2)
05167 Kaposi sarcoma-associated herpesvirus infection
100027579 (PLCG2)
05169 Epstein-Barr virus infection
100027579 (PLCG2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
100027579 (PLCG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100027579 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mdo04131
]
100027579 (PLCG2)
Enzymes [BR:
mdo01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
100027579 (PLCG2)
Membrane trafficking [BR:
mdo04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
100027579 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
100027579 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF-hand_PLCG2
C2
SH3_1
SH3_9
PH
PH_12
EF-hand_PLCG1
SH2_1
SH3_2
EF-hand_like
PH_14
GDPD
Motif
Other DBs
NCBI-GeneID:
100027579
NCBI-ProteinID:
XP_001371778
Ensembl:
ENSMODG00000015196
UniProt:
F7BVQ1
LinkDB
All DBs
Position
1:523811063..523991606
Genome browser
AA seq
1264 aa
AA seq
DB search
MTTKINIDTLPEYEKSQIKRTLELGTVMTLFSLKKSNPERRTVQVITETRQVAWSKTADK
IEGFLDLMEIKEIRPGKNSKDFERGKASRQKEDCCFTIFYGTQFVLNTLSLAADSKDDAS
KWLCGLTILHQEAQNASTPTITESWLRKQIYSVDQTRKNSITFRELKTILPLVNFKVSSA
KFLKDKFLEIGAYKDELSFEQFHLFYKKMMFDQQKSILDEFKKDSSVFILGNTDRPDASA
IHLHDFQRFLMHEQQETWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSKENS
IWDDKYDSVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTESYIRCLRMGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVQAIRDHAFVSSQFPVILSIEEHCCVEQQRHMARV
FKEVFGDLLLTRPTEASADQLPSPAQLKEKIIIKHKKLGPRGDVDINIEDKKEEKKQQGE
LYMWDTIDQKWYRHYCAIADEKLSFSDDIEQNMEEDSVKDVAQTDLHFGEKWFHKRMEKR
TSAEKLLQEYCAETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTPEGGAMKYY
LTDNLMFNSIYDLIQHYREAHLRCAEFELRLTDPVPNPNPHESKAWYYDSLSRGEAEDML
MRIPRDGAFLIRKREGGDAYAITFRAKGKVKHCRINKDGHHFVLGTSAYFESLVELVSYY
EKHALYRKMRLRYPVTPELLERYNTERDINSLYDVRMYVDPSEINPSTPQRTVKALYDYK
AKRRDELSFCRGALIHNVSKEPGGWWKGDYGGRIQQYFPSNYVEDISTVDFEELEKQIIE
DNPLGSLCRGILDLNTYNVVKVPHGKNQKSFVFILEPKNPNDPPVEFATDKVEELFEWYQ
SIREITWKNATVETNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVET
KADSIVRQKPIDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGAQMVALNFQTADKYM
QLNHALFALNGRTGYVLQPESMRNENYDPTPLESQRKILMTLTVKVLGARHLPKLGRSIA
CPFVEVEICGTEYDNNKFKTTVVNDNGLSPVWASTQEKVTFEIYDPNLAFLRFVVYEEDM
FSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCR
QLRRRQEELNNQLFLYDTHQNIRNANRDALVNEFNVNENQLQLYQEKCNRRLREKRVSNS
KFYS
NT seq
3795 nt
NT seq
+upstream
nt +downstream
nt
atgaccaccaagatcaacatagacacccttcccgaatatgagaaaagtcagatcaagcgg
actctggaattgggaactgtcatgaccttgtttagcctcaagaagtctaaccctgagagg
agaacggtccaggtcatcacggagaccaggcaggtggcctggagcaagacggctgacaag
attgaaggattcttggacttaatggagataaaggaaatccgtccagggaaaaattcaaaa
gactttgaacgtgggaaagcaagtcgccagaaagaagattgctgcttcaccatattttat
ggcactcagtttgtcctcaacaccctgagtttagcagctgactccaaggatgacgctagt
aaatggctttgtggcttgacaattttgcaccaagaagcccagaatgcctcaacaccaact
attactgagagctggctaagaaagcaaatttattctgtagatcaaactcggaaaaatagt
atcaccttccgagaactgaagaccattcttcccttagtaaacttcaaagttagtagtgcc
aagttcctgaaggacaaattcctggaaataggtgcctacaaggatgaactcagctttgaa
cagttccacttattctacaaaaagatgatgtttgatcaacagaaatcaattcttgatgag
ttcaaaaaagattcatctgtgtttattctgggaaatacagaccggccagatgcatctgcc
attcacttgcatgatttccagaggtttctgatgcatgaacagcaggaaacctgggcacag
gatctaaataaagtaagagagaggatgaccaaatttatagatgacactatgagagaaaca
gctgagccattcctgtttgtcgatgagttccttacttacctgttttcaaaagaaaacagc
atttgggatgataaatatgactctgttgacatgcaagacatgaataaccccttgtctcat
tactggatttcttcatctcataacacatacctcaccggggaccaacttcgaagtgaatct
tctactgaatcgtacattcgatgtcttcgaatgggttgccggtgtatagagttggattgc
tgggatgggcctgatgggaagccgatcatctatcatggctggacacggacgacgaaaatc
aagtttgacgatgtggtgcaggccatcagagaccatgcttttgtctcctcacagttccca
gtgatcctctccattgaagaacactgctgtgtggaacagcaacgtcatatggccagggta
tttaaggaagtttttggagacctcctccttacaaggcccactgaagccagtgccgaccag
cttccatcccctgcccagctgaaagaaaagatcatcattaagcacaagaagctgggtccc
agaggagatgtggacatcaacattgaagacaagaaagaggaaaaaaaacagcaaggagaa
ctgtacatgtgggacaccattgatcagaaatggtatcgccattattgtgctatagctgat
gagaagctgtctttcagtgatgatatagaacagaatatggaggaggattctgtaaaggat
gtagcacagactgacctgcattttggtgagaagtggtttcataaaagaatggagaagaga
acaagtgctgagaaactattgcaagaatactgtgctgaaaccgggggcaaggatggaacc
ttcttagtccgtgaaagcgagactttccccaatgattatacattgtccttctggagatca
ggcagagtccagcactgtcgaatacggtcgactcctgagggaggggccatgaaatactat
ttgactgacaacctcatgttcaacagcatctatgacttgattcaacactaccgagaagcc
cacctgagatgtgctgaatttgaacttcgtttgacagacccagtgcccaaccccaatcct
catgaatcaaaagcttggtactatgatagcctgagcagaggagaagccgaagacatgttg
atgagaattccccgagatggagccttcctgattaggaaaagagaagggggagatgcgtac
gccattactttcagagccaagggaaaagtgaagcattgccggattaacaaagatgggcat
cattttgtgctggggacatctgcttactttgaaagtttggtagaattggtcagctactat
gaaaagcatgcgctctacaggaagatgaggctgcgctaccccgtgactcctgaattgctg
gagcgttacaacactgaaagggacataaattcgctctatgatgtcaggatgtatgtggat
cccagtgaaattaacccctcaacgcctcagagaaccgtgaaggctctatatgactacaaa
gccaagcgtagggatgagctcagcttctgtcggggagccctcatccacaacgtctccaag
gagcctggtggctggtggaagggtgattatggaggaaggattcagcaatattttccatct
aattatgtggaggacatatcaacagttgatttcgaagagctggaaaaacagattattgaa
gataaccctttaggatccctatgcagaggaatcttggacctcaacacttacaatgttgtg
aaagtaccacatgggaaaaatcagaaatcgtttgtgttcatcctggaacccaagaatccc
aatgatcctcctgtggagtttgcaacagacaaagtggaagaactctttgagtggtaccag
agcatcagagaaatcacttggaagaatgcgacagtggagaccaacatgaaatattgggag
aagaaccaatcaattgccatagagctatctgacttagtcgtctactgtaaaccaaccagc
aaaaccaaggataatctagaaaatcctgatttcagagaaattcgctcttttgtggagacc
aaggctgacagcatcgttaggcagaagccgattgatctcttgaaatacaatcaaaaggga
ctgactcgggtctacccgaaaggccaaagggtggactcatcaaattatgatccttttcga
ctctggctttgtggcgctcagatggttgctctgaatttccagacagcagacaaatatatg
cagctaaaccatgctttatttgcacttaatggccggactggttatgtcctacagcctgaa
agcatgaggaatgaaaactatgatccgacacccctggaatcacaaaggaagatcctgatg
actctcactgtgaaggtcttgggggcccgccatcttcccaagcttggccgaagcattgcc
tgtccatttgtagaggtggaaatttgtggcactgagtatgataataacaaattcaagaca
acggtagtaaatgataatggtctgagtccagtctgggcgtctactcaggaaaaagtgaca
tttgaaatttatgacccaaatctcgcatttctacgttttgttgtttatgaggaggatatg
ttcagcgatcccaactttctggcacatgccacttatcccattaaaggaatcaaatcaggg
tttagatctgttcctcttaaaaatggttacagtgaagatattgaactggcctcccttttg
gttttctgtgagatgcgccctgtcttggaaagcgaagaagagctctattcttcctgtcgc
caacttcgaaggcggcaagaggagctgaacaaccaactctttctctatgacactcatcag
aacatacgcaatgctaacagagatgccctggtgaatgaattcaatgtcaatgaaaatcag
ttgcagctgtatcaggaaaaatgcaacaggaggttaagggagaagagagttagtaacagc
aaattctactcctag
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integrated database retrieval system
