Monodelphis domestica (gray short-tailed opossum): 100029625
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Entry
100029625 CDS
T01031
Symbol
EGFR
Name
(RefSeq) epidermal growth factor receptor
KO
K04361
epidermal growth factor receptor [EC:
2.7.10.1
]
Organism
mdo
Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo01521
EGFR tyrosine kinase inhibitor resistance
mdo01522
Endocrine resistance
mdo03272
Virion - Hepatitis viruses
mdo04010
MAPK signaling pathway
mdo04012
ErbB signaling pathway
mdo04014
Ras signaling pathway
mdo04015
Rap1 signaling pathway
mdo04020
Calcium signaling pathway
mdo04066
HIF-1 signaling pathway
mdo04068
FoxO signaling pathway
mdo04072
Phospholipase D signaling pathway
mdo04144
Endocytosis
mdo04151
PI3K-Akt signaling pathway
mdo04510
Focal adhesion
mdo04520
Adherens junction
mdo04540
Gap junction
mdo04630
JAK-STAT signaling pathway
mdo04810
Regulation of actin cytoskeleton
mdo04912
GnRH signaling pathway
mdo04915
Estrogen signaling pathway
mdo04921
Oxytocin signaling pathway
mdo04926
Relaxin signaling pathway
mdo04928
Parathyroid hormone synthesis, secretion and action
mdo04934
Cushing syndrome
mdo05160
Hepatitis C
mdo05163
Human cytomegalovirus infection
mdo05165
Human papillomavirus infection
mdo05171
Coronavirus disease - COVID-19
mdo05200
Pathways in cancer
mdo05205
Proteoglycans in cancer
mdo05206
MicroRNAs in cancer
mdo05207
Chemical carcinogenesis - receptor activation
mdo05208
Chemical carcinogenesis - reactive oxygen species
mdo05210
Colorectal cancer
mdo05212
Pancreatic cancer
mdo05213
Endometrial cancer
mdo05214
Glioma
mdo05215
Prostate cancer
mdo05218
Melanoma
mdo05219
Bladder cancer
mdo05223
Non-small cell lung cancer
mdo05224
Breast cancer
mdo05225
Hepatocellular carcinoma
mdo05226
Gastric cancer
mdo05230
Central carbon metabolism in cancer
mdo05231
Choline metabolism in cancer
mdo05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mdo00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03272 Virion - Hepatitis viruses
100029625 (EGFR)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100029625 (EGFR)
04012 ErbB signaling pathway
100029625 (EGFR)
04014 Ras signaling pathway
100029625 (EGFR)
04015 Rap1 signaling pathway
100029625 (EGFR)
04630 JAK-STAT signaling pathway
100029625 (EGFR)
04066 HIF-1 signaling pathway
100029625 (EGFR)
04068 FoxO signaling pathway
100029625 (EGFR)
04020 Calcium signaling pathway
100029625 (EGFR)
04072 Phospholipase D signaling pathway
100029625 (EGFR)
04151 PI3K-Akt signaling pathway
100029625 (EGFR)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100029625 (EGFR)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100029625 (EGFR)
04520 Adherens junction
100029625 (EGFR)
04540 Gap junction
100029625 (EGFR)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100029625 (EGFR)
09150 Organismal Systems
09152 Endocrine system
04912 GnRH signaling pathway
100029625 (EGFR)
04915 Estrogen signaling pathway
100029625 (EGFR)
04921 Oxytocin signaling pathway
100029625 (EGFR)
04926 Relaxin signaling pathway
100029625 (EGFR)
04928 Parathyroid hormone synthesis, secretion and action
100029625 (EGFR)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100029625 (EGFR)
05206 MicroRNAs in cancer
100029625 (EGFR)
05205 Proteoglycans in cancer
100029625 (EGFR)
05207 Chemical carcinogenesis - receptor activation
100029625 (EGFR)
05208 Chemical carcinogenesis - reactive oxygen species
100029625 (EGFR)
05230 Central carbon metabolism in cancer
100029625 (EGFR)
05231 Choline metabolism in cancer
100029625 (EGFR)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100029625 (EGFR)
09162 Cancer: specific types
05210 Colorectal cancer
100029625 (EGFR)
05212 Pancreatic cancer
100029625 (EGFR)
05225 Hepatocellular carcinoma
100029625 (EGFR)
05226 Gastric cancer
100029625 (EGFR)
05214 Glioma
100029625 (EGFR)
05218 Melanoma
100029625 (EGFR)
05219 Bladder cancer
100029625 (EGFR)
05215 Prostate cancer
100029625 (EGFR)
05213 Endometrial cancer
100029625 (EGFR)
05224 Breast cancer
100029625 (EGFR)
05223 Non-small cell lung cancer
100029625 (EGFR)
09172 Infectious disease: viral
05160 Hepatitis C
100029625 (EGFR)
05171 Coronavirus disease - COVID-19
100029625 (EGFR)
05163 Human cytomegalovirus infection
100029625 (EGFR)
05165 Human papillomavirus infection
100029625 (EGFR)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100029625 (EGFR)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100029625 (EGFR)
01522 Endocrine resistance
100029625 (EGFR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mdo01001
]
100029625 (EGFR)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mdo04147
]
100029625 (EGFR)
Enzymes [BR:
mdo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100029625 (EGFR)
Protein kinases [BR:
mdo01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
100029625 (EGFR)
Exosome [BR:
mdo04147
]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
100029625 (EGFR)
Exosomal proteins of pancreatic cancer cells
100029625 (EGFR)
Exosomal proteins of bladder cancer cells
100029625 (EGFR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Kinase-like
Haspin_kinase
ABC1
Motif
Other DBs
NCBI-GeneID:
100029625
NCBI-ProteinID:
XP_007500445
Ensembl:
ENSMODG00000009033
UniProt:
F7B2I8
LinkDB
All DBs
Position
6:complement(259367779..259617098)
Genome browser
AA seq
1213 aa
AA seq
DB search
MGLYGAAGAAVLVLLVGHFSQGLALEEKKVCQGTSNKLTQLGTFEDHFVSLQRMFNNCEV
VLGNLEITYVQKNYDLSFLKTIQEVAGYVLIALNAVEKIPLENLQVIRGNVLYENFYALS
VLSNYDVNKTGVKELPMRNLLEILIGGVRFNNNPSLCNVETIQWKDIVNPIYINNITIDN
NSHPKSCEKCDSSCPNGSCWGPGPQYCQTLTKTICAQQCSGRCRGSSPSDCCHNQCAAGC
TGPRESDCLVCRKFRDEATCKDNCPSLLQYNPTTYQMDVNPDGKYSFGATCVRKCPHNYV
VTDHGSCVRSCNADTYEVEEDGVRKCKKCEGPCSKVCNGIGIGEFKDVLSINATNIKQFQ
NCTIISGDLHILPVAFKGDSFTNTPPLDPRELNILRTVKEISGFLLIQSWPENMTDLHAF
EHLEIIRGRTKQHGQFSLAVVDVNISSLGLRSLKEISDGDVIISKNRRLCYANTINWTKL
FGTKSQKAKITNNKDERECRALGHVCHELCSSDGCWGPKPSHCLSCRHVSRHKKCVEKCN
ILEGEPREYMENLKCMQCHSECLPQVMNLTCTGPGPDKCIQCAHYIDGPHCVKTCPAGIM
GENDTLVWKYADADKVCQRCHPNCTYGCEGPGLEGCPTPGPKIPSIATGIIGGLLLLVVL
GLGIGLFFRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGS
GAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGI
CLTSTVQLITQLMPFGCLLDYIREHKDNIGSQYLLNWCVQIAKGMSYLEERRLVHRDLAA
RNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSY
GVTVWELMTFGSKPYDGIPASDISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPK
FRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSKFYRTLMEEEDMEDIVDADEYLIPQ
QGFFNSPSTSRTPLLSSLSATSNNSATVCIDRNGQTCPGKEENFIQRYSSDPTTVLTEDN
VDDSFQPVPEYINQSAPKNPTGSAIQNPVYHNQPLNPDASKDSLYQNSHNNSAVDNPEYL
NTTQPNLAKKAFDSNSCWNPTAKHPINLDNPDYQQDFFPQEAKPNGVFKVPAAENPEYLR
VAAQQSEFIQASA
NT seq
3642 nt
NT seq
+upstream
nt +downstream
nt
atggggctctacggggctgcaggagccgctgtcctggtgctgcttgtcggacacttctcc
cagggcttggcgctggaggaaaaaaaagtttgccaaggaacaagtaacaaactgacgcag
ttgggtacttttgaggaccacttcgtgagtctccagaggatgttcaataactgtgaggtg
gtgcttggaaatttagaaattacctacgtccaaaaaaattatgacctgtccttcctcaag
accatccaggaggttgctggctacgtgcttattgcactcaatgcagtagagaaaatccct
ttggaaaatctgcaagtcatcagaggaaatgtgttgtatgaaaacttttatgctctttct
gtgctatccaactatgatgtgaataaaaccggagtgaaggaactgcccatgaggaatcta
ctagaaatccttattggtggtgttcgattcaacaataacccatctttgtgtaatgtggag
acgatccagtggaaggatattgtgaaccctatctacatcaacaacatcaccatagacaat
aacagccatccaaagagttgtgaaaagtgtgattctagttgtcccaatgggagctgttgg
ggtcctgggccacaatattgccagactttgacaaaaaccatctgtgcccagcagtgctca
ggacggtgtcgtggtagttcccccagcgactgttgccacaaccagtgtgcagcgggttgt
actggaccccgagagagtgactgcttggtctgccgaaagtttcgagatgaagccacgtgc
aaagacaattgcccctctctgctgcaatacaacccaaccacataccagatggacgtcaac
ccagatggcaaatacagctttggggccacctgtgttcgcaaatgcccacataactatgtg
gtgacagaccatggttcctgtgttcgttcctgtaatgctgacacctatgaagtggaagaa
gatggtgtccgaaaatgtaaaaagtgtgaaggtccatgtagtaaagtttgcaatggaata
ggaatcggtgaatttaaagatgttctctccatcaatgcaacaaacatcaaacaattccag
aactgtaccataatcagcggtgatctgcatatcttgcccgttgcatttaaaggggattcc
ttcaccaatactccacctctggatcccagagaactgaatattctcagaactgtaaaagaa
atatcaggatttttgctgattcagtcttggcctgaaaacatgactgacctccatgctttt
gaacatctggaaattatacgaggcagaacaaagcagcatggccagttttctcttgctgtt
gttgatgtgaacataagttccttgggcttacgctcccttaaggaaatcagtgatggggat
gtcatcatttccaagaacagaagactctgctatgcaaacacaataaactggacgaaattg
tttggaacaaaaagtcagaaagccaaaatcaccaacaacaaagatgaaagagagtgccgt
gctctgggtcatgtttgtcatgagttatgctcatctgatggttgctggggtccaaagcca
agccactgcttgtcctgtcgccatgtgagtcgtcacaagaaatgtgttgagaaatgcaac
attctggaaggagagccaagggaatatatggagaatctgaaatgtatgcagtgccactct
gagtgtctgcctcaagtgatgaatctaacctgcactggaccgggtcctgacaaatgtatc
cagtgtgctcattatatagatggtccacactgtgtgaaaacttgtccagctggaatcatg
ggagaaaatgataccttggtctggaaatatgctgatgcagataaggtttgccaacgatgc
catccaaattgtacctatgggtgtgaaggaccaggtcttgaaggttgtcccacacctggc
cccaagattccttccattgccactggaattataggtggccttctcttactagtggtgttg
ggccttggcattggtctcttctttcgaaggcgccatattgttcgtaaacgcacactgcgc
aggctgctacaggaaagggagcttgttgagcctcttacccccagtggagaagctccgaac
caagctcttttgaggatcctaaaggagacagaatttaaaaagatcaaagttcttggctct
ggagcttttggcacagtgtataagggactgtggattccagaaggagagaaggtgaaaatt
cctgttgccattaaagaattaagagaggccacttctccgaaagccaataaggaaattctt
gatgaagcctatgtgatggccagtgtagacaatccccatgtatgtcgtctcctgggaatc
tgtctgacttccacagtccaactcataacacagctcatgccattcggctgcctcctggac
tacatacgagaacacaaggacaatattggctcccagtaccttctcaactggtgtgtgcag
attgccaaggggatgagttacctagaagagcgccgcttggtacaccgtgacttagcagcc
agaaatgtccttgtaaagacacctcaacatgtcaagatcacagattttgggctggcaaaa
ttacttggtgctgaggagaaagaataccatgcagaaggaggcaaggtgcctattaaatgg
atggctctggaatcgattttacaccgtatttatacccaccaaagtgatgtctggagctat
ggtgtcaccgtgtgggagctgatgacgtttgggtccaagccttacgatgggatccctgca
agtgacatttcatcgatattagagaaaggggagcgccttcctcagccacccatctgcacc
attgatgtctacatgatcatggtcaaatgctggatgatagatgctgatagtcgccccaag
tttcgtgagttaatcatagaattctctaaaatggcccgtgatccccaacgctaccttgtt
atacagggagatgaaagaatgcacttaccaagccccacagactccaaattttatcgcacc
ctaatggaagaggaggacatggaagatatcgtcgatgcggatgagtaccttatcccacag
caagggttcttcaatagcccttccacatctcggactcctctcctaagctctctgagtgct
accagcaataattctgccacagtgtgcattgacagaaacgggcagacttgtcctggaaag
gaagaaaacttcatccagagatacagttctgatcctactactgtcttaactgaagacaat
gtggatgacagcttccagcccgtaccggaatatataaaccagtcggctccaaaaaacccc
acaggctctgccatccagaaccctgtttatcacaatcagcctttaaatccagatgcctct
aaagactctctgtaccaaaattcacacaacaacagtgcagtggacaaccctgagtatctc
aacacaacccagcccaacttggccaaaaaggcattcgacagcaattcctgctggaaccca
acagccaagcacccgatcaatctggacaaccccgactaccaacaggacttcttcccccag
gaagccaagccaaatggggtttttaaagtccctgctgcggaaaatcctgagtacctcagg
gtagcagcccaacaaagcgaattcattcaagcttcagcatga
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