Monodelphis domestica (gray short-tailed opossum): 100618058
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Entry
100618058 CDS
T01031
Symbol
SOS1
Name
(RefSeq) SOS Ras/Rac guanine nucleotide exchange factor 1
KO
K03099
son of sevenless
Organism
mdo
Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo01521
EGFR tyrosine kinase inhibitor resistance
mdo01522
Endocrine resistance
mdo04010
MAPK signaling pathway
mdo04012
ErbB signaling pathway
mdo04014
Ras signaling pathway
mdo04062
Chemokine signaling pathway
mdo04068
FoxO signaling pathway
mdo04072
Phospholipase D signaling pathway
mdo04150
mTOR signaling pathway
mdo04151
PI3K-Akt signaling pathway
mdo04510
Focal adhesion
mdo04540
Gap junction
mdo04630
JAK-STAT signaling pathway
mdo04650
Natural killer cell mediated cytotoxicity
mdo04660
T cell receptor signaling pathway
mdo04662
B cell receptor signaling pathway
mdo04664
Fc epsilon RI signaling pathway
mdo04714
Thermogenesis
mdo04722
Neurotrophin signaling pathway
mdo04810
Regulation of actin cytoskeleton
mdo04910
Insulin signaling pathway
mdo04912
GnRH signaling pathway
mdo04915
Estrogen signaling pathway
mdo04917
Prolactin signaling pathway
mdo04926
Relaxin signaling pathway
mdo04935
Growth hormone synthesis, secretion and action
mdo05034
Alcoholism
mdo05160
Hepatitis C
mdo05161
Hepatitis B
mdo05163
Human cytomegalovirus infection
mdo05165
Human papillomavirus infection
mdo05200
Pathways in cancer
mdo05205
Proteoglycans in cancer
mdo05206
MicroRNAs in cancer
mdo05207
Chemical carcinogenesis - receptor activation
mdo05208
Chemical carcinogenesis - reactive oxygen species
mdo05210
Colorectal cancer
mdo05211
Renal cell carcinoma
mdo05213
Endometrial cancer
mdo05214
Glioma
mdo05215
Prostate cancer
mdo05220
Chronic myeloid leukemia
mdo05221
Acute myeloid leukemia
mdo05223
Non-small cell lung cancer
mdo05224
Breast cancer
mdo05225
Hepatocellular carcinoma
mdo05226
Gastric cancer
mdo05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mdo00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100618058 (SOS1)
04012 ErbB signaling pathway
100618058 (SOS1)
04014 Ras signaling pathway
100618058 (SOS1)
04630 JAK-STAT signaling pathway
100618058 (SOS1)
04068 FoxO signaling pathway
100618058 (SOS1)
04072 Phospholipase D signaling pathway
100618058 (SOS1)
04151 PI3K-Akt signaling pathway
100618058 (SOS1)
04150 mTOR signaling pathway
100618058 (SOS1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100618058 (SOS1)
04540 Gap junction
100618058 (SOS1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100618058 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100618058 (SOS1)
04660 T cell receptor signaling pathway
100618058 (SOS1)
04662 B cell receptor signaling pathway
100618058 (SOS1)
04664 Fc epsilon RI signaling pathway
100618058 (SOS1)
04062 Chemokine signaling pathway
100618058 (SOS1)
09152 Endocrine system
04910 Insulin signaling pathway
100618058 (SOS1)
04912 GnRH signaling pathway
100618058 (SOS1)
04915 Estrogen signaling pathway
100618058 (SOS1)
04917 Prolactin signaling pathway
100618058 (SOS1)
04926 Relaxin signaling pathway
100618058 (SOS1)
04935 Growth hormone synthesis, secretion and action
100618058 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
100618058 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
100618058 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100618058 (SOS1)
05206 MicroRNAs in cancer
100618058 (SOS1)
05205 Proteoglycans in cancer
100618058 (SOS1)
05207 Chemical carcinogenesis - receptor activation
100618058 (SOS1)
05208 Chemical carcinogenesis - reactive oxygen species
100618058 (SOS1)
05231 Choline metabolism in cancer
100618058 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
100618058 (SOS1)
05225 Hepatocellular carcinoma
100618058 (SOS1)
05226 Gastric cancer
100618058 (SOS1)
05214 Glioma
100618058 (SOS1)
05221 Acute myeloid leukemia
100618058 (SOS1)
05220 Chronic myeloid leukemia
100618058 (SOS1)
05211 Renal cell carcinoma
100618058 (SOS1)
05215 Prostate cancer
100618058 (SOS1)
05213 Endometrial cancer
100618058 (SOS1)
05224 Breast cancer
100618058 (SOS1)
05223 Non-small cell lung cancer
100618058 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
100618058 (SOS1)
05160 Hepatitis C
100618058 (SOS1)
05163 Human cytomegalovirus infection
100618058 (SOS1)
05165 Human papillomavirus infection
100618058 (SOS1)
09165 Substance dependence
05034 Alcoholism
100618058 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100618058 (SOS1)
01522 Endocrine resistance
100618058 (SOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_19
PH_10
PH_13
RHG20_PH
IQ_SEC7_PH
Takusan
Motif
Other DBs
NCBI-GeneID:
100618058
NCBI-ProteinID:
XP_003339823
Ensembl:
ENSMODG00000008801
LinkDB
All DBs
Position
1:661712818..661874746
Genome browser
AA seq
1333 aa
AA seq
DB search
MQALQLQYEFFSEENAPKWRGLLVTALKKVQMQVHPTLASNEDALQYVEELILQLLSMLC
QAQPRSVLDVEDRVQKSFPHPIDKWAIADAQSANEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGQETCYDLVKAFMPEVRQYIRELNLLTKVFSDPLVXLSPFKLFS
SHDVENIFSRIADIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESY
AQDILRPGFHDHFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLK
QLEEKSEDQEDKECLKQAITALLNLQSSMERICSKSLAKRRLSESACRFYSQQMKGKQLA
IKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQP
RLPGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDESVIFSAKSAEEKNNWMA
ALISLQYRSTLERMLDVTMLQEEKEEQMRLPSSDLYRFAEPDSEENIVFEENMQPKSGIP
IIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEAD
RIAMENGDQPLSVELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDTDLLQRLEEFIG
TVRGKAMKKWVESITKIIQRKKMARDNGPGHNITFESSPPAVEWHISRPGHTETFDLLTL
HPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCI
VEAENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKK
ILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFS
KRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPR
NPKPLPRFPKKYNYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASA
PNSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSSDTIFIQVTLPHGPRSASVSSIS
LTKSTDEMTIPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKVYSPRYSDR
TSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSEHGNTFFPNSPSPFTPPPP
QTPSPHGTRRHLPSPPLTQQDVDLHSIPGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
RDGPPLLENAHSS
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgctgcagctgcagtacgagttcttcagcgaggagaacgcgcccaagtggagg
gggctgctggtgacggccctgaaaaaggtgcagatgcaagtccatcctacacttgcatca
aatgaggatgctctccaatatgttgaagagttaattctacagctgttaagtatgctgtgc
caagctcaaccccgaagcgttttagatgttgaggatcgtgtacaaaaaagttttcctcat
ccaattgataagtgggcaatagctgatgctcaatctgctaatgaaaagaggaagcgaaga
aatccattatctctcccagtagaaaaaattcaccccttattaaaggaagttctagggtat
aaaattgaccaccaagtttctgtttacatagtagcagtattagaatacatttctgcagat
attttaaagctggttggaaattacgtacggaatatacgacattatgaaattacaaaacag
gacattaaagtagcaatgtgtgccgataaggtattgatggatatgttccatcaagatgta
gaagatataaatatattatctttaactgatgaagaaccttccacttcaggacaggaaaca
tgctatgacctggtaaaggcatttatgcctgaagttcgacaatatataagggaacttaat
cttcttactaaagtttttagcgatccattagtcnatttgtctccattcaaattgttttct
tcccacgatgtagaaaatatatttagtcgtatagcagatattcatgaactcagtgttaaa
ttattgggccacatagaagacactgtagaaatgacagacgaaggcagtccccatccatta
gttggtagctgctttgaagacttagcagaggaattggcatttgatccatatgaatcgtat
gctcaagatattttacgacctggttttcatgaccactttcttagtcaattatccaagccg
ggggcagccctctatttgcagtcaataggtgaaggtttcaaagaagctgttcagtatgtt
ttacccaggttacttctagcacctgtgtaccattgtctacattactttgaacttttaaag
caattagaagaaaagagtgaagaccaggaagacaaagaatgtttgaaacaggcaatcact
gctttgcttaaccttcagagcagtatggaaagaatatgttccaagagtcttgcaaaacgg
agactgagtgaatctgcatgtcgattttatagccaacagatgaaggggaaacaactagca
ataaagaaaatgaacgaaattcagaagaacattgatggttgggagggaaaagacattgga
cagtgttgcaatgagtttatcatggaaggaacccttactcgtgtaggtgccaaacatgag
agacatatctttctctttgatggcttaatgatttgctgtaaatcaaatcatggtcagcca
agacttcctggtgctagcaatgctgagtatcgtctcaaagagaagttttttatgcgcaag
gtacaaatcaatgataaagatgacactaatgaatacaagcatgcctttgaaataatttta
aaagatgaaagtgttatattttctgccaagtctgctgaggagaaaaacaactggatggca
gcattgatatccttacaataccgcagtactctagaaaggatgctggatgtaacaatgtta
caagaagaaaaggaggagcagatgaggcttccaagttctgatctttatagatttgcagaa
ccagactctgaagaaaatattgtatttgaagaaaacatgcaacccaaatctggaattcca
atcatcaaagcaggaactgttattaaacttatagagcgactcacctaccatatgtatgct
gatcccaatttcgttcggacatttcttacaacttatagatctttctgcaagcctcaagag
ctactgagtcttctgatagagaggtttgaaattccagaacctgagccaacagaggctgat
agaattgctatggagaatggagatcaaccccttagtgtagaactaaaacgatttagaaaa
gaatacatacagcctgttcaactccgagtgctaaatgtatgtcgacattgggtagaacac
cacttctatgattttgaaagagatacagatcttttgcaacgattagaagaatttattgga
acagtaaggggcaaagcaatgaagaaatgggttgaatctatcactaaaatcatccaacgg
aaaaaaatggcaagagataatgggccaggacataatataacatttgaaagttcacctcct
gcagttgagtggcatataagcagacctggacacacagagacttttgacctgctcaccttg
cacccaatagaaattgctcgacagctcactttacttgaatcagatctctaccgagctgta
cagccatcagaattagttggaagcgtatggacaaaagaagacaaagaaattaattctcct
aaccttttgaaaatgatccgccacacaactaatctaactttgtggtttgaaaagtgtatc
gtggaagcagaaaacctagaagaaagagtagcagtggtgagtcgaataattgagattctt
caagtctttcaagaactgaacaactttaatggtgtacttgaagttgtcagtgccatgaac
tcatcacctgtttatagactggaccacacatttgagcaaattccaagtcgccaaaagaaa
attttagaggaagctcatgaactaagtgaagatcattataaaaaatatttggcaaaactc
aggtctattaatccaccatgtgtgcctttctttgggatttatttgacaaatatcttgaaa
acagaagaaggcaatcctgaagtgttgaaaagacatggaaaagaacttataaattttagc
aaaagaagaaaagttgcagaaataacaggagaaatacagcagtaccaaaatcaaccatac
tgtttgcgagtagaatctgatatcaaaagattctttgagaatttgaatccaatgggaaat
agcatggaaaaagaatttacagattatctgttcaacaagtcactggaaattgaaccaaga
aaccctaagcctctaccaagatttccaaaaaaatataattatcccctcaagtctcctggt
gttcgtccatcaaacccaagaccaggtaccatgagacatcctacaccactgcaacaggag
ccaaggaagattagttacagtcggatccctgaaagtgaaacagagagtacagcatctgca
cctaactctccacggacaccattaacacctccccctgcctctggtgcttccagtaccacc
gacgtgtgcagtgtgtttgattctgatcattcaagcccttttcactcaagcagcgatacc
atctttatccaagttacactgccccatggcccaagatctgcttcagtatcgtcaataagt
ttaaccaagagcactgatgaaatgaccatccccccacctgtgccccccagaagacgacca
gaatcagccccagcagaatcttctccctccaagatcatgtccaaacatttggatagccct
ccagcaattcctcctcggcagcccacatcaaaagtgtattcgccacgttactcagaccgg
acctcgatatcagaccccccggaaagccctccccttttaccaccaagagaacccgtgagg
acccctgatgttttctccagctctccactacatctccagccaccccctttgggcaaaaaa
agcgaacatggcaatactttcttcccaaacagcccctccccttttacgcccccccctcct
cagacaccttctcctcatggcaccaggagacatctgccatcgccaccattgacacagcag
gatgtggaccttcattccatccctgggccacctgttcctccacgacaaagcacttctcaa
cacatccccaaacttcctccaaaaacttacaaaagggagcacacgcacccctccatgcat
cgagatggaccacctttattggagaatgcccattcctcctga
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integrated database retrieval system
