Myotis daubentonii (Daubenton's bat): 132211932
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Entry
132211932 CDS
T10294
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
mdt Myotis daubentonii (Daubenton's bat)
Pathway
mdt01521
EGFR tyrosine kinase inhibitor resistance
mdt04062
Chemokine signaling pathway
mdt04081
Hormone signaling
mdt04148
Efferocytosis
mdt04151
PI3K-Akt signaling pathway
mdt04217
Necroptosis
mdt04550
Signaling pathways regulating pluripotency of stem cells
mdt04630
JAK-STAT signaling pathway
mdt04658
Th1 and Th2 cell differentiation
mdt04659
Th17 cell differentiation
mdt04725
Cholinergic synapse
mdt04917
Prolactin signaling pathway
mdt04920
Adipocytokine signaling pathway
mdt04933
AGE-RAGE signaling pathway in diabetic complications
mdt04935
Growth hormone synthesis, secretion and action
mdt05140
Leishmaniasis
mdt05145
Toxoplasmosis
mdt05152
Tuberculosis
mdt05161
Hepatitis B
mdt05164
Influenza A
mdt05167
Kaposi sarcoma-associated herpesvirus infection
mdt05168
Herpes simplex virus 1 infection
mdt05200
Pathways in cancer
mdt05207
Chemical carcinogenesis - receptor activation
mdt05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mdt05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mdt00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
132211932 (JAK2)
04151 PI3K-Akt signaling pathway
132211932 (JAK2)
09133 Signaling molecules and interaction
04081 Hormone signaling
132211932 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
132211932 (JAK2)
09143 Cell growth and death
04217 Necroptosis
132211932 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
132211932 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
132211932 (JAK2)
04659 Th17 cell differentiation
132211932 (JAK2)
04062 Chemokine signaling pathway
132211932 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
132211932 (JAK2)
04917 Prolactin signaling pathway
132211932 (JAK2)
04935 Growth hormone synthesis, secretion and action
132211932 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
132211932 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
132211932 (JAK2)
05207 Chemical carcinogenesis - receptor activation
132211932 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
132211932 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
132211932 (JAK2)
05164 Influenza A
132211932 (JAK2)
05168 Herpes simplex virus 1 infection
132211932 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
132211932 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
132211932 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
132211932 (JAK2)
05140 Leishmaniasis
132211932 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
132211932 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
132211932 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
132211932 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mdt01001
]
132211932 (JAK2)
Enzymes [BR:
mdt01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
132211932 (JAK2)
Protein kinases [BR:
mdt01001
]
Non-receptor tyrosine kinases
JAK family [OT]
132211932 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
Kdo
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
132211932
NCBI-ProteinID:
XP_059512714
LinkDB
All DBs
Position
11:complement(32977988..33091250)
Genome browser
AA seq
1132 aa
AA seq
DB search
MEMACLTMTEMEGTCTPPMHQNGDIPGITDSVKQTDPVLQVYLYHSLGKTEGDYLKFSTG
EYVAEEICVAASKACGITPVYHSMFALMSETERIWYPPNYVFHIDESTRHNVLYRIRFYF
PYWYCSGSNRTYRHGISRGAEAPLLDDFVMSYLFAQWRHDFLHGWIKVPVTHETQEECLG
MAVLDMMRIAKENDQTPLDIYSSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIEQF
SHCKATAKNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSR
GKHKESETLTEQDLQLYCDFPDIIDVSIKQASQEGSNESRIVTIHKQDGKNLEIELSSLK
EALSFVSLIDGYYRLTADAHHYLCKEVASPVVLENIQSNCHGPISMDFAISKLKKAGNQT
GLYVLRCSPKEFNKYFLTFAVERDNVIEYKHCLITKNENGEYNLSGTKKNFNNLKDLLNC
YQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNSVSDVPTSPTLQRHNNVNQMVFHKI
RNEDLVFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWA
MHFLEEKNLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISVTVLPKDILQERIPWVP
PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW
YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
LLKNNGRLPRPDGCPDEIYVIMTECWNNNVNQRPSFRNLALRVDQIRDSIAG
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atggaaatggcttgcctcacaatgacagaaatggaaggaacatgtacacctcctatgcat
cagaatggagatattcctggaattactgattctgtgaagcaaacagatccagtccttcag
gtgtatctttatcattcccttgggaaaactgagggagattacctgaagttttcaactggg
gaatatgttgcagaagaaatttgtgttgctgcttctaaagcctgtggaatcacacctgtg
tatcatagtatgtttgctttaatgagtgaaacagaaaggatctggtatccgcccaactat
gtcttccatatagatgagtcaaccaggcacaatgtactctacagaataagattttacttt
ccttactggtattgtagcggcagcaacagaacttatcggcatggaatatctcgaggtgct
gaagctcctcttcttgatgactttgttatgtcttacctttttgctcagtggcggcatgat
tttttgcatggatggataaaagtacctgtgactcatgaaacacaggaagaatgtcttggg
atggcagtgttagatatgatgagaatagccaaagaaaatgatcaaaccccactcgacatc
tatagctctatcagctataagacattcttaccaaaatgtattcgagcaaagatccaagac
tatcatattttgacaagaaagcgaataaggtaccgatttcgcagatttattgagcaattc
agccattgcaaagccactgccaaaaacttgaaacttaagtatcttataaatctggaaact
cttcagtctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaaagtgaaacactgacagaacaggatttacagttatattgtgacttt
cccgatattattgatgtcagtattaagcaggcaagccaagaaggctcaaatgaaagcaga
attgtaactatccataagcaagatggtaaaaatctggaaattgaacttagttcattaaag
gaggctttgtcttttgtgtcattaattgatggatattatagattaactgcagatgcacac
cattacctctgtaaagaagtagcatctccagtggtgcttgaaaatatacaaagcaattgt
catggcccaatttcaatggattttgccataagtaaactgaagaaagcaggtaatcagact
ggactttatgtacttcgatgcagtcctaaggagtttaataaatattttttgacttttgct
gtcgagcgtgataatgtcattgaatataagcactgtttgattacaaaaaatgagaatgga
gaatacaacctcagtggaactaagaagaacttcaataatcttaaagatcttttgaattgc
taccagatggaaactgttcgctcagacaatataattttccagtttacaaaatgctgtcct
ccaaagccaaaagataaatcaaaccttctagtctttagaacaaatagtgtttctgatgta
ccaacctcaccaacattacagagacataataatgtgaaccaaatggtgtttcacaaaatc
cgaaatgaagatttagtatttaatgaaagtcttggccaaggcacttttacaaaaattttt
aaaggtgtaagaagagaagtaggagattatggtcaactgcatgaaacagaagttctttta
aaagttctggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatg
atgagccagctttctcacaagcatctggttttaaattatggagtatgtgtctgtggagag
gagaatattctggttcaggagtttgtgaaatttggatcactagatacatatttgaaaaag
aataaaaattctataaatatattatggaaacttgaagtggctaaacagttggcatgggcc
atgcattttctagaagaaaaaaaccttattcatgggaatgtatgtgccaaaaacattcta
cttatcagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcct
ggcattagtgttacagttttgccaaaggacattcttcaggagagaataccatgggtacca
cctgaatgtattgaaaatcctaaaaacttaaacttggcaacagacaaatggagttttggt
accactttgtgggaaatctgcagtggaggagacaagcctctgagtgctttggattctcaa
agaaagctacagttttatgaagatagacaccagcttcctgcaccaaagtggacagaatta
gcaaatcttattaataattgtatggattatgaaccagattttagaccttctttcagagcc
atcatacgagatcttaatagtttgtttactccagattatgaattgttaacagagaatgac
atgttaccaaatatgaggataggtgccctagggttttctggagcttttgaagaccgagac
cctactcagtttgaagagagacacttgaaatttctgcagcaacttggcaagggtaacttt
gggagtgttgagatgtgccggtatgaccctctacaagacaacactggggaggtggtggct
gtgaaaaagctccagcacagtactgaagagcacctcagagactttgaaagggaaattgaa
atccttaaatccctgcagcatgacaacattgtaaagtacaagggagtgtgctacagtgct
ggccggcgtaatctaagattaattatggaatatttaccatatggaagtttacgggactat
ctccaaaagcataaagaacgaatagatcataagaaacttctgcaatatacatctcagata
tgcaagggtatggaatatcttggtacgaaaaggtatatccacagggatctggcaacaagg
aatatattggtagagaatgaaaacagagttaaaattggagattttgggttaaccaaagtc
ttgccacaagacaaagaatactacaaagtgaaagaacctggtgaaagccctatattctgg
tatgctccagaatcactgacagagagcaagttttctgtggcctcagatgtgtggagcttt
ggagtggttctatatgaacttttcacctatattgagaagagtaaaagtccaccagcggaa
ttcatgcgtatgattggcaacgacaaacaagggcagatgattgtgtttcatttgatagaa
ctcttgaagaataatggaagattaccaagaccagatggatgcccagatgagatctatgtg
atcatgacagaatgctggaataataatgtaaatcaacgtccgtctttcagaaacctagct
cttcgagttgatcaaataagggacagcatagctggatga
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