KEGG   Myotis daubentonii (Daubenton's bat): 132212570
Entry
132212570         CDS       T10294                                 
Symbol
NOTCH1
Name
(RefSeq) neurogenic locus notch homolog protein 1 isoform X1
  KO
K02599  Notch 1
Organism
mdt  Myotis daubentonii (Daubenton's bat)
Pathway
mdt01522  Endocrine resistance
mdt04330  Notch signaling pathway
mdt04658  Th1 and Th2 cell differentiation
mdt04919  Thyroid hormone signaling pathway
mdt05020  Prion disease
mdt05165  Human papillomavirus infection
mdt05200  Pathways in cancer
mdt05206  MicroRNAs in cancer
mdt05224  Breast cancer
Brite
KEGG Orthology (KO) [BR:mdt00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    132212570 (NOTCH1)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    132212570 (NOTCH1)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    132212570 (NOTCH1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    132212570 (NOTCH1)
   05206 MicroRNAs in cancer
    132212570 (NOTCH1)
  09162 Cancer: specific types
   05224 Breast cancer
    132212570 (NOTCH1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    132212570 (NOTCH1)
  09164 Neurodegenerative disease
   05020 Prion disease
    132212570 (NOTCH1)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    132212570 (NOTCH1)
SSDB
Motif
Pfam: EGF hEGF EGF_TEN EGF_CA EGF_2 Ank_2 Ank Notch NOD NODP Ank_5 Ank_4 Ank_3 EGF_Teneurin EGF_3 Gurken_M
Other DBs
NCBI-GeneID: 132212570
NCBI-ProteinID: XP_059514485
LinkDB
Position
11:81282330..81326810
AA seq 2544 aa
MPPLLAPLLCLALLPALGARGLRCSQPSETCLNGGSCEVLPNGTEACVCSEAFVGQRCQV
HSPCLSAPCRNGGTCHVLDRGGLADYTCSCRLGFSGPLCLTPQDNACLPNPCRNGGTCDL
LTLADYKCLCPPGWSGKTCQQADPCASNPCANGGQCLPFEASYICRCPPGFHGPTCRQDV
NECGMSPPPCRHGGTCLNEVGSYRCVCRATHTGQHCELPYVPCSPSPCQNGGTCRPTGDT
THECACLPGFTGQNCEENVDDCPGNSCQNGGTCVDGVNTYNCRCPPEWTGQYCTKDMDEC
QLMPNACQNGGTCHNTQGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYC
ECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYMGPACSQDVDECSLG
ANPCEHKGKCINTLGSFECRCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICM
PGYEGVHCEVNRDECASSPCLQNGRCLDKINEFQCECPTGFTGNLCQYDVDECASTPCKN
GAKCLDGPNTYSCVCTEGYTGPHCEVDIDECDPDPCHYGSCKDGVAAFTCLCRPGYTGHH
CETNINECHSQPCRHGGTCQDRDNAYLCLCLKGTTGPNCEINLDDCASNPCDSGTCLDKI
DGYECACEPGYTGSMCNINIDECAGGPCHNGGTCEDGTNAFTCRCPEGYHGPSCLSEVNE
CSSDPCAHGSCRDGLNGYRCDCDPGWSGANCDVNNNECESNPCVNGGTCKDMTSGYVCTC
REGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCASSPCR
NSGECRASEDYESFSCVCPAGWQGQTCEVDINECVKSPCRHGASCQNTNGGYRCHCQAGY
TGRNCETDIDDCRPNPCHNGGSCTDGVNAAFCDCLPGFQGAFCEEDINECASNPCRHGAN
CTDCVASYTCTCPPGFSGIHCENNTPDCTESSCFNGGTCVDGIDSFTCLCPPGFTGSYCE
HDINECDSRPCLHGGTCQDSYGTYKCTCPLGYTGLNCQNLVRWCDSSPCKNGGKCLQTNV
LYRCECHSGWTGLYCDVPSVSCEAAARERGIDVTHLCRNGGLCMDADNTHHCRCQPGYTG
SYCEDQVDECSPSPCQNGATCTDYPGGYSCECVAGYHGVNCSEEINECLSHPCQNGGTCI
DLTNTYKCSCPRGTQGVHCEINVDDCNPPIDPVSRGPKCFNNGTCVDQVGGYSCTCLPGF
VGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRPGHTGRRCESVINGCKGKPCKNG
GACAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLSPFT
GPECQFPASSPCVGGNPCYNQGTCEPTSESPYYRCLCPAKFNGLLCHILDYSFRGGAGLD
IAPPQIEEACELPECREEAGNKACSVRCNNHACGWDGGDCSLNFNDPWQNCTQALECWKY
FSNGHCDSQCNSAGCLFDGFDCQHAEGQCNPLYDQYCKDHFSDGHCDQGCNRAECEWDGL
DCAEHVPERLAAGTLVVVVLMPPAQLRNDSLRFLRELSRLLHTNVVFKRDASGQQMIFPY
YGREEELRKHPIRRSVDADGWAAPGALLGQVKAALLPGGGGGRWRRELDPMDIRGSIVYL
EIDNRQCVQASAQCFQSTTDVAAFLGALASLGSLNIPYKIEAVQSETVEPPPPPPLHFMY
VAVAAFLLLCFGGCGVLLSRQRRRQHGQLWFPEGFKVSEASKKKRREPLGEDSVGLKPLK
NSSDGALIDDNQNEWGDEDLETKKFRFEEPVVHPELDDQTDHRQWTQQHLDAADLRVSAM
APTPPQGEADADCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEEEDAPAVISDFIYQGA
SLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQ
ILIRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAV
NNVEAALVLLKNRANKDMQNNKEETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPR
DIAQERMHHDIVRLLDEHSLVRSPPLHGALGGAPTLSPPLCSPNGYLGNLKPAAPGKKAR
KPSTKGLAGGKEARDLRARRKKAQDGKACLLDSSSALSPVDSLESPHGYLSDVASPPLLP
SPFQPSPSVPLNHLPGMPDTHLGLGHLGVAAKPEMAALGGGGRLAFEAGPPRLSHLPVAS
STGPVLGTGGSGAVNFTVGGTTGLNSQCEWLSRLQNGLVPNQYNPLRGNVAPGSLSAQAP
ALQHGVMGPLHGGLSASTLSQMLSYQALPSTRLATQPHLVQPQQVQQQVQQPPSIQQQQN
LPPPPPHLGVSSAAGGHLGRSFLGGEPSQADVQPLGPGLAAHTILPQDSQALPTALPSSL
GPPMATAQFLTPPSQHSCSSSPVDNTPSHQLQVPEHPFLTPSPESPDQWSSSSPHSNISD
WSEGISSPPTSTQSQIAHIPEAFK
NT seq 7635 nt   +upstreamnt  +downstreamnt
atgccaccgctcctggcgcccctgctctgcctggcgctgctgcccgcgctcggcgcacga
ggcctgcgatgttcccagcccagcgagacctgcctgaacggcgggagttgtgaagtgctc
cccaacggcacggaggcctgtgtctgcagcgaggccttcgtgggccagcggtgccaggtg
cacagcccctgcctcagcgccccctgcaggaacggcgggacgtgccacgtgctggaccgg
ggcggcctggcggactacacctgcagctgccgcctgggcttctccgggcccctctgcctg
acgccccaagacaacgcctgcctccccaacccctgccgcaacggcggcacctgcgacctg
ctcacgctcgccgactacaagtgcctctgtccccccggctggtcagggaagacgtgccag
caggcggacccgtgtgcctccaacccctgtgccaacggcggccagtgcctgcccttcgag
gcctcctacatctgccgctgcccgcccggcttccacggccccacctgcaggcaggacgtg
aacgagtgtggcatgagccccccgccctgccgccacgggggcacctgcctcaacgaggtc
ggctcctaccgctgtgtctgccgcgccacccacaccggccagcactgcgagctgccctac
gtgccctgcagcccctccccctgccagaacgggggcacctgccggcccacgggcgacacc
acgcacgagtgcgcctgcctgccaggcttcaccggccagaactgcgaggagaacgtcgat
gactgtccgggaaacagctgccagaacgggggcacctgcgtggacggcgtgaacacctac
aactgccgctgcccgcccgagtggacaggtcagtactgcaccaaggacatggacgagtgc
cagctcatgcccaacgcctgccagaacggcggcacctgccacaacacccagggcggctac
aactgcgtgtgcgtcaacggctggacgggcgaggactgcagcgagaacatcgacgactgc
gccagcgcggcctgcttccacggcgccacctgccacgaccgcgtggcctccttctactgc
gagtgtccccacggccgcacaggtctgctgtgccacctcaacgacgcctgcatcagcaac
ccctgcaacgagggctccaactgcgacaccaaccccgtcaacggcaaggccatctgcacc
tgtccctcggggtacatggggccggcctgcagccaggacgtggacgagtgctcgctgggt
gccaacccctgtgagcacaagggcaagtgcatcaacacactgggctccttcgagtgccgg
tgcctgcagggctacaccggcccgcgctgcgagatcgacgtcaacgagtgcgtctcgaac
ccgtgtcagaatgacgccacctgcctggaccagatcggggagttccagtgcatctgcatg
cccggctacgagggtgtgcactgcgaggtgaaccgggacgagtgtgccagcagcccctgc
ctgcagaacggccgctgcctggacaagatcaacgagttccagtgcgagtgccccacaggc
ttcaccgggaacctgtgccagtacgacgtggacgagtgcgccagcacgccctgcaagaac
ggcgccaagtgcctggacgggcccaacacctacagctgcgtgtgcacggaaggctacacg
gggccccactgcgaggtggacatcgacgagtgtgaccccgacccctgccactacgggtcc
tgcaaggatggcgtggccgccttcacctgcctgtgccggcccggctacacgggtcaccac
tgcgagaccaacatcaacgagtgccacagccagccctgccgccacgggggcacctgccag
gaccgtgacaacgcctacctctgcctttgcctcaaggggaccacaggacccaactgtgag
atcaacctggacgactgtgccagcaacccctgcgactcgggcacgtgcctggacaagatc
gacggctatgagtgcgcctgcgagccgggctacacggggagcatgtgcaacatcaacatc
gacgagtgcgccggcggcccctgccacaacggcggcacctgcgaggacggcaccaacgcc
ttcacctgccgctgccccgagggctaccacggcccctcctgcctgtccgaggtcaacgag
tgcagcagcgacccctgcgcccacgggtcctgccgggatggcctcaacgggtacagatgt
gactgcgaccccggctggagcggggccaactgtgacgtcaacaacaacgagtgcgagtcg
aatccctgtgtcaacggcgggacctgcaaggacatgaccagcggctacgtgtgcacctgc
cgagaaggcttcagcggccccaactgccagaccaacatcaacgagtgtgcgtccaacccc
tgtctgaaccagggcacctgcatcgatgacgtggcagggtacaagtgcaactgcctgctg
ccctacacaggagccacgtgtgaggtggtgctggccccgtgtgcctccagcccctgcagg
aacagcggcgagtgcagggcgtccgaggactacgagagcttctcctgcgtgtgcccggcc
ggctggcaggggcagacctgcgaggtggacatcaacgagtgcgtgaagagcccgtgccgc
cacggcgcctcctgccagaacaccaacggcggctaccgctgccactgccaggcgggctac
acggggcgcaactgcgagacggacatcgacgactgccggccgaacccgtgccacaacggc
ggctcctgcacggatggcgtcaacgcggccttctgcgactgcctgcccggcttccagggc
gccttctgcgaggaggacatcaacgagtgcgccagcaacccctgccgccacggcgccaac
tgcacggactgcgtggccagctacacctgcacctgccccccgggcttcagcgggatccac
tgcgagaacaacacgcccgactgcaccgagagctcctgcttcaatggcggcacctgtgtg
gacggcatcgactccttcacctgcctgtgcccgcctggcttcacgggcagctactgtgag
cacgacatcaacgagtgcgactcgcggccctgcctgcacggcggcacctgccaggacagc
tacggcacctacaagtgcacctgcccgctgggctacaccggcctcaactgccagaacctg
gtgcgctggtgtgactcctcgccctgcaagaacggcggcaagtgcttgcagaccaacgtc
ctgtaccgctgcgagtgccacagcggctggaccggcctctactgcgacgtgcccagtgtg
tcctgcgaggcggccgcccgggagcgaggcatcgacgtgacccacctgtgccggaacggc
gggctctgcatggacgcggacaacacgcaccactgccgctgccagccgggctacacgggc
agctactgcgaggaccaggtggacgagtgctcgcccagcccctgccagaatggggccacc
tgcaccgactaccccggcggctattcctgcgagtgtgtggctggctaccacggggtgaac
tgctccgaggagatcaacgagtgcctgtcccacccgtgccagaacggcggcacctgcatc
gacctcaccaacacctacaagtgctcctgtccccggggcacacagggcgtgcactgcgag
atcaacgtggacgactgcaacccccccatcgaccccgtgtcccgtggccccaagtgcttc
aacaacggcacctgcgtggaccaggtgggcggctactcctgcacctgcctgcccggcttc
gtgggcgagcgctgcgagggcgatgtcaacgagtgtctctccaacccctgtgacgcccgc
ggcacccagaactgcgtgcagcgcgtcaacgacttccactgcgagtgccgccccggccac
accgggcgccgctgcgagtccgtcatcaacggctgcaaggggaagccctgcaagaacggt
ggcgcctgcgccgtggcctccaacaccgcccgcggcttcatctgcaagtgcccggcgggc
ttcgagggcgccacgtgcgagaatgacgcacgcacctgcggcagcctgcgctgcctgaac
ggcggcacctgcatctcgggcccgcgcagccccacctgcctgtgcctgagccccttcacg
ggccccgagtgccagttcccggccagcagcccctgcgtgggcggcaacccctgctacaac
cagggcacctgcgagcccacctccgagagcccctactaccgctgcctgtgccccgccaag
ttcaacgggctcctgtgccacatcctggactacagcttccggggcggcgcgggcctggac
atcgccccgccgcagatcgaggaggcctgcgagctgcccgagtgccgcgaggaggcgggc
aacaaggcgtgcagcgtgcgctgcaacaaccacgcgtgcggctgggacggcggcgactgc
tccctcaacttcaacgacccctggcagaactgcacgcaggcgctggagtgctggaagtac
ttcagcaacggccactgcgacagccagtgcaactcggccggctgcctcttcgacggcttt
gactgccagcacgccgagggccagtgcaaccccctgtacgaccagtactgcaaggaccac
ttcagcgacggccactgcgaccagggctgcaacagggccgagtgcgagtgggacgggctg
gactgcgcggagcacgtgcccgagcgcctggcggccggcacgctggtggtggtggtgctc
atgccgcccgcgcagctgcgcaacgactcactccgcttcctgcgggagctcagccgcctg
ctgcacaccaacgtggtcttcaagcgcgacgccagcggccagcagatgatcttcccctac
tacggccgcgaggaggagctgcgcaagcaccccatcaggcgctccgtggacgcggacggc
tgggccgcgcccggtgccctgctcggccaggtcaaggccgcgctgctcccgggcggcggg
ggcgggcgctggcgccgggagctggacccgatggacatccgtgggtccatcgtctacctg
gagatcgacaaccggcagtgcgtgcaggcctccgcccagtgcttccagagcaccaccgac
gtggccgccttcctgggcgcgctcgcctcgctgggcagcctcaacatcccctacaagatc
gaggccgtgcagagtgagacggtggagccgcccccgcccccgccgctgcacttcatgtac
gtggccgtggccgccttcctgctgctctgcttcgggggctgcggcgtgctcctgtcgcgc
cagcgccggcggcagcatggccagctctggttccccgagggcttcaaggtgtcggaggcc
agcaagaagaagcggcgcgagcccctcggcgaggactccgtgggcctcaagcccctgaag
aactcctcggacggcgccctcatagatgacaatcagaacgagtggggtgatgaggacctg
gagaccaagaagttccggttcgaggagccggtggtgcatcccgagctggatgaccagacg
gaccaccggcagtggacgcagcagcacctggacgccgccgacctgcgggtgtccgccatg
gcgcccacgccgccccagggcgaggccgacgccgactgcatggacgtcaacgtccgcggg
cccgacggcttcacacccctcatgatcgcctcctgcagcggagggggcctggagacgggc
aacagcgaggaggaggaggacgccccggccgtcatctcggacttcatctaccagggcgcc
agcctgcacaaccagaccgaccgcaccggagagacggccctgcacctggccgcccgctac
tcgcgctccgacgcggccaagcgcctgctggaggccagcgctgacgccaacatccaggac
aacatgggtcgcacccccctgcacgcggccgtgtccgccgatgcccagggcgtcttccag
atcctgatccggaaccgagccacggacctggacgcccgcatgcacgacggcaccacgccg
ctgatcctggccgcgcgcctggcggtggagggcatgctggaggacctcatcaactcgcac
gccgacgtcaacgccgtggacgacctgggcaagtccgccctgcactgggccgccgccgtg
aacaacgtggaggccgcactcgtgctcctgaaaaacagggccaacaaggacatgcagaac
aacaaggaggagacgcccctgttcctggccgcccgcgagggcagctacgagacggccaaa
gtgctgctggaccacttcgccaaccgggacatcacggaccacatggaccggctgccgcgg
gacatcgcgcaggagcgcatgcaccacgacatcgtgcggctgctggacgagcacagcctg
gtgcgcagccccccgctgcacggcgccctgggcggcgcgcccaccctgtcgcccccgctc
tgctcgcccaacggctacctgggcaacctcaagccggccgcgccgggcaagaaggcacgc
aagcccagcaccaagggcctggccggcggcaaggaggcccgggacctcagggcgcggcgg
aagaaggcacaggacggcaaggcctgcctgctggacagctccagcgcgctgtcgcccgtg
gactccctcgagtcgccccacggctacctgtcagacgtggcctcgccgcccctcctgccc
tcccccttccagccgtctccgtcggtgcccctcaaccacctgccgggcatgcccgacacc
cacctgggcctgggccacctgggagtggcggccaagcccgagatggcagccctgggtggg
ggtggccggctggccttcgaggcggggccgccgcgcctctcccacctgcccgtggcctcc
agtaccggcccagtcctggggaccggcggcagcggggccgtgaatttcaccgtgggcggg
accacgggcttgaacagccagtgtgagtggctgtcccggctgcagaacggcctggtgccc
aatcagtacaaccccctgcgcgggaacgtggcgcccggctcgctgagcgcgcaggctccc
gccctccagcacggcgtgatgggcccgctgcacggcggcctctctgcctccaccctgtcc
cagatgctgagctaccaggccctgcccagcacgcggctggccacccagccccacctggtc
cagccccagcaggtgcagcagcaggtgcagcagccgccgagcatccagcagcagcagaac
ctgccgccgcccccgccgcacctgggcgtgagctcggccgccggcgggcacctgggccgg
agcttcctgggcggggagccgagtcaggcggacgtgcagccgctgggccccggcctggcg
gcgcacaccatcctgccccaggacagccaggccctgcccacggcgctgccgtcctcgctg
ggcccgcccatggccaccgcccagttcctgacgccgccctcccagcacagctgctcctcc
tcgcccgtggacaacacccccagccaccagctgcaggtgcccgagcaccccttcctcacc
ccgtcccccgagtcccccgaccagtggtccagctcttccccccactccaacatctccgat
tggtccgagggcatctccagcccgcccaccagcacgcagtcccagatcgcccacatcccg
gaggcgttcaagtaa

DBGET integrated database retrieval system