Myotis daubentonii (Daubenton's bat): 132214156
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Entry
132214156 CDS
T10294
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
mdt Myotis daubentonii (Daubenton's bat)
Pathway
mdt00562
Inositol phosphate metabolism
mdt01100
Metabolic pathways
mdt04014
Ras signaling pathway
mdt04015
Rap1 signaling pathway
mdt04020
Calcium signaling pathway
mdt04024
cAMP signaling pathway
mdt04070
Phosphatidylinositol signaling system
mdt04919
Thyroid hormone signaling pathway
mdt04933
AGE-RAGE signaling pathway in diabetic complications
mdt05205
Proteoglycans in cancer
Module
mdt_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
mdt00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
132214156 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
132214156 (PLCE1)
04015 Rap1 signaling pathway
132214156 (PLCE1)
04020 Calcium signaling pathway
132214156 (PLCE1)
04070 Phosphatidylinositol signaling system
132214156 (PLCE1)
04024 cAMP signaling pathway
132214156 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
132214156 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
132214156 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
132214156 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mdt04131
]
132214156 (PLCE1)
Enzymes [BR:
mdt01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
132214156 (PLCE1)
Membrane trafficking [BR:
mdt04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
132214156 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
132214156 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
132214156
NCBI-ProteinID:
XP_059516819
LinkDB
All DBs
Position
13:41112124..41404321
Genome browser
AA seq
2296 aa
AA seq
DB search
MTSEEMAASDLIPVTQRKVVSSQSAADESSEKASGVSVPKTHTPGQSRPTSHTISKLNKP
KEETSGSNLPRIFSTTRGKIMSDENSNETCWEKNMPDSVKNLNVNGNNILENRQCGLPQS
QFYKTCDSVVEEGLHLETGISSSLERKVFPGIQLELDEPPMGIRPLENQSATGRAHPDSD
LAVFHFHYELDRRMSDSVSTLSDNLILDDCGNCVSLPDVGREQKKNYMAYTCKLMELAKS
CDNENKQLQGDHCDALNDEYMCCEASCRKASVVCSSDSFCREGFTDSPSAETFLSHFEDF
PDNCEDVEDYFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLAAWSYI
DMKRSGSLLPCGRVTGQLSTVLVRQDGSPCLSEAQWYPIYNAVRRGEETEDTIGSLLHFF
TKLPASETAYERINVGPCLKQCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGARSGL
LSTFGGSTGRMMLKERQPGTSMANSSALPSSSAGISKELIDLQPLIQFPEEVASILMEQE
QNIYRRVLPVDYLCFLTQNLSTPECQRSLPCLKASISASILNSQNREHNALEDLVMRFNE
VSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNTVMEFLAGLRSRKVLKMWQFM
DQSDLETMRSLKDAMAQHESSCEYRKVVTRALHIPGCRVVPFCGVFLKELCEVLDGASGL
VKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSRSLEA
EDEDSPSEGSGSRKNSLKDKAPRCQFVIGDLLDTENDIFEQPKEWDPHGLEEPQKAFDHG
IELIPWYVLSIRADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWIKPTTASPA
SAKAKLGMPTATSEPGKFPLLGNAGLSGLAEGVLDLFSVKAVYMGHPSIDIHTVCVQNKL
SSMLLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQQW
LRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSAEKPNMQRNNTLGIS
TAKKKKKILMRGESGEATDDEMATRKAKLHKECRSWSGSDPQDINEQEESEANAITSPPN
PLPSRRAHSLTTAGSPILAAGTSSPIRPVSSPVLSSNKSPSSAWSSSSWHGRIKGGMRGF
QSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDLYAVPCNRSGSESAPLYTNLTIDEN
TSGLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLGVFG
VGILQLNDFLVNCQGEHCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKDNFASK
NDESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDG
DDGMPIIYHGHTLTTKIPFKDVIEAIDRSAFINSDLPIIISIENHCSLPQQRKMADIFKT
VFGEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQ
AQAYNGGNVNPPPTNNEEEEDEEDEYDYDYESLSDDNILEDRPESKSCSDKLQFEYNEEI
PKRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTL
NASGSNRGKERKSRKSIFGNNPGRMSPGETASLNKTSGKSSYEGMRQAWEESSSPLSPAT
SLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNPLM
FWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDL
DNMEPAVYSLTIVSGQNVCPSNSTGSPCIEVDILGMPLDSCHFRTKPIHRNTLNPMWNEQ
FFFRVHFEDLIFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFV
NSRRMEEISSGSSVPASLMFSTEERKCLQTHRVTVHGVPGPEPFTVFSINGGTKAKQLLQ
QILTTEQDTKPIAADYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIVQILSSWFPEEGY
VGRIVLKTQQENLEEKSIVQDDREVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQD
VIQQTLCKAKYSYSILSNPNPNDYVLLEEVVKDTANKKSSTPKSSQRVLLDQECVFQAQS
KWKGAGKFILKLKEQVQASREDKRKGISFASEFKKFTKSTKQPRGLTSPSQVLVSESVQN
KEERPVGGSDTMDYRQ
NT seq
6891 nt
NT seq
+upstream
nt +downstream
nt
atgacttctgaagaaatggcagcttctgatctcatacctgtgactcagagaaaagtggtg
tcttctcagtcagctgcagatgaaagtagtgaaaaggcctcaggcgtcagtgttccaaag
acacatactcctgggcagagtaggccgacttctcataccatctcaaaactgaacaaaccc
aaagaggaaacttctggaagcaacttgcctaggattttctcaacaacaagggggaaaatc
atgagtgatgagaacagtaatgaaacgtgctgggagaaaaacatgcccgattctgtgaag
aaccttaacgtgaacggcaacaacatattggaaaaccgtcagtgtggtcttcctcagagc
cagttttacaaaacatgcgattctgttgtagaggaaggcctgcatttggaaactggaatc
tcttcttccctggaaagaaaggtgttccctgggattcaactggaactagacgaacctccc
atgggcattcgtcccttagaaaatcagtcagcaacaggcagggcacaccctgacagtgat
ttggcagtatttcactttcattatgaacttgacagaagaatgtcagacagtgtctctacc
ctatcagacaacttgattttggatgattgtggaaactgtgtatcactgcctgatgttggt
agggagcaaaagaaaaattatatggcatatacttgcaaactgatggaattggcaaaaagc
tgtgataatgagaacaagcagctacagggtgatcattgtgacgccttgaacgatgaatac
atgtgctgcgaagcttcctgccgaaaagccagcgtggtatgttctagtgacagcttctgc
agggagggttttactgatagtccatctgccgagacttttctgagccattttgaggacttc
cctgataactgtgaagatgtagaagattattttaaaagtaaaaaggagcgatccactttg
ttagtgaggagattttgtaaaaatgacagagaagttaagaaatctgtgtatactgggaca
agggcaattgtgaggactctgccttctggtcacattggactggcagcttggagttacatt
gatatgaagagaagtggaagcttgttgccttgtgggagagtaacgggccagctatcaaca
gtgctggttaggcaagatgggagcccctgtctgtcagaagcccagtggtatccgatctac
aatgcagtgagaaggggagaagaaacagaagacacaattggatctcttctccatttcttc
acaaagctcccagcctctgagacagcctatgaaaggattaatgttggtccctgcttaaag
caatgtgttcgagacaccgtatgtgagtatcgtgccaccctccaacggacctccatatct
cagtacatcacgggttctctcctagaagcaaccacatctttaggagcaagaagtgggctt
ctcagtacttttggaggatccaccggacgaatgatgctgaaagaacgccaaccgggcacc
tctatggccaattccagtgccctcccttcaagttcagctgggatcagcaaggagctgatt
gatctgcagcccctcatccagttccccgaggaagtcgccagcatcctgatggagcaggaa
cagaatatctaccggagggtcttgccggttgactatctttgcttcttgacccagaacttg
agcactccagaatgtcagaggtccctgccctgcctcaaagcatccatctcagcatcaatt
cttaactcccagaacagagagcacaatgcccttgaagatcttgtgatgagatttaatgag
gtgagctcctgggtgacgtggctgatcctcacagccggctccatggaggagaagcgggaa
gtcttctcatatttggtgcatgtggccaaatgctgctggaacatgggcaactacaacacc
gtcatggagttcttggccggcctcaggtcaagaaaagttttaaaaatgtggcagttcatg
gaccagtctgacctggagaccatgaggagtctgaaggatgccatggctcagcacgaatcc
tcctgcgagtacaggaaggtggtgacgcgggcgctgcacatcccgggctgcagggtggtc
ccgttctgcggggtgtttctgaaggagctctgtgaagtgctggacggcgcctccggcctc
gtgaagctctgccccagatacaattcccaggaggaaaccctagagtttgtagctgactac
agtggacaagataattttttacaacgcgtgggacaaaatggcttgaagaattcggaaaaa
gagtccaccgtcaacagcatctttcagatcatcaggagctgcagccgcagtctggaggcg
gaggacgaggacagccccagtgaggggagcggctctcggaaaaactccctgaaggacaaa
gctcctcgctgccagtttgtaattggagatttgctagatacagaaaatgacatctttgag
cagcccaaagagtgggaccctcatggattagaagagccacagaaggcctttgaccacggg
atagagctcatcccatggtatgtgctgtccatccgagctgacgtgcaccagttcctgctg
cagggggccacggtcatccactatgaccaggacacgcacctctctgcccgctgcttcctc
cagcttcagcctgacaatagcaccttgacctggataaagcccaccacagcctccccagcc
agtgcaaaagcaaaacttggtatgcctactgccacgtccgagcctggcaaattcccatta
ctgggcaacgctggattaagtggcctggcggagggggtcttggatctgttttccgtaaag
gctgtgtacatggggcaccctagcattgatatacacactgtgtgtgttcagaacaaactg
agtagcatgcttctctcggagactggtgtgacactgctctatgggcttcagaccacggac
aatagattactgcactttgtggcaccgaagcacacagctaaaatgctcttcagtggattg
ttggaactcactagagctgtgagaaagatgaggaagttccctgaccaaagacagcagtgg
ctgcggaaacagtacgtcagcctctatcaggaggatggacggtatgaaggcccaactttg
gctcacgctgtggagttgtttggtggcagacgatggagtactcgaaaccccagccctggg
acatcagcaaagagtgccgagaagcccaacatgcagaggaacaacaccctgggcatcagt
actgccaagaagaagaagaaaatccttatgaggggtgagagtggagaggccaccgacgac
gagatggccacccgaaaggccaaactgcacaaagagtgtcgaagctggagtggctctgat
cctcaggacattaacgagcaagaggagtcagaggcgaatgccatcacaagcccgcctaac
cctctcccttccagaagagcccattctctgactacggctgggtcccccatcttggctgcc
gggacgtcatctcccatcaggccagtgtcctcccctgtgctgtcttcaaacaagagcccg
tccagtgcctggagcagcagcagctggcacggccgcatcaaaggaggaatgagaggcttc
cagagcttcatggtttccgacagcaacatgagtttcgttgaatttgtggagctgttcaaa
tccttcagtgtaaggagccgcaaggacctgaaggatctcttcgacctctacgccgtgccc
tgcaaccggtcgggctctgagtcggccccgctctacaccaacctaaccattgacgagaac
accagcggtcttcagcctgatctagatttgttgaccagaaatgtctcagatttggggctg
ttcattaagagtaaacagcagctgtcagacaaccagaggcagatctctgacgccattgct
gctgcaagcatcgtgacgaatggcactggggtcgagagcacatccctgggcgtgtttggg
gtcggcatacttcagctcaatgacttcctagtgaactgccagggagaacactgcacttac
gatgaaatcctcagcatcatccagaagtttgagcctagcattagtatgtgtcatcagggc
ctaatgtcatttgaaggatttgcaaggtttctgatggataaagacaactttgcttcgaaa
aacgatgaatcacaggagaacattaaagaattacagctgcccctctcctactattacatt
gaatcttcacacaatacctacctcacaggccatcagctcaaaggagaatcctcagtagaa
ctctatagccaggtcctcctgcaaggctgtaggagcgtagagttggactgctgggacgga
gatgatgggatgcccatcatttaccatggacatacactgacaaccaagatccccttcaag
gacgtgatcgaagccattgatcgcagtgccttcatcaactctgacctgccaatcatcata
tcaattgaaaaccactgttcattgcctcagcaacgaaaaatggcagacattttcaagact
gtatttggagaaaaactggtggctaagttcttatttgaaagtgatttctcagatgatcca
atgcttccttcccctgaccaacttagaaggaaggtgcttctcaaaaataagaagctaaaa
gcccaccagacgccggtggatatcttaaagcaaaaggctcatcagttagcatccatgcaa
gctcaggcttacaatggtgggaatgtcaaccccccacctactaataatgaggaggaggaa
gatgaagaagacgagtatgattatgactatgaatctctctctgatgataacattctagaa
gacagacctgaaagcaaatcgtgtagcgacaagcttcagtttgagtataatgaagaaatc
cccaagaggataaagaaagcagataactctgcttgcaacaaaggaaaggtgtatgacatg
gagttgggagaagaattttatcttcctcagaataaaaaggaaagcagacagattgcacca
gagctttccgaccttgtcatctattgccaagcagtaaaattcccaggcctgtcaactcta
aatgcatctggctctaacagaggaaaagaaaggaaaagcaggaagtccatttttggcaac
aatccgggcagaatgagccctggggagacggcatcacttaacaaaacgtctggaaaaagt
tcctatgaaggaatgcgacaggcctgggaggagtcttcttcccccctcagcccagccacg
tccctcagcgctatcattagaactcccaaatgttaccatatctcatcgctgaatgaaaat
gccgccaaacgtctgtgtcgcaggtattctcagaaactgatccagcacaccgcctgccag
ctgctgaggacttacccggctgccacccgcatcgactcctccaaccccaaccccctcatg
ttctggctgcacgggatacagctcgtggcactcaactaccagacagatgatctcccttta
catttaaacgctgccatgtttgaggccaacggtggctgtggctatgtgttgaaaccccca
gttctgtgggacaagaactgccccatgtatcagaagttttctcccctggaaagagacctg
gacaacatggagcccgctgtctactctttgactattgtctctggccagaacgtgtgcccg
agcaacagcacaggaagcccgtgcatcgaggtcgacatcctgggcatgccgctggacagc
tgccacttccgcacgaagcccatccaccggaacactctgaaccccatgtggaacgagcag
tttttcttccgggttcactttgaagacctcatatttcttcgttttgcagttgtggaaaac
aacagctcggcggtcactgctcagaggatcatcccgctcaaggctctaaagcgaggatat
cgacatcttcagctgcgaaacctccacaatgaagtcttggaaatctctagtttattcgta
aacagcagaaggatggaagaaatctcctctggcagttccgtgccagcctctttgatgttt
agtacagaagaaagaaagtgtctgcagactcacagagtcacggtgcatggggtcccaggt
ccggagcccttcactgttttctctataaatggaggcaccaaggcaaagcaacttctccag
caaattctgaccactgaacaagacaccaaacctattgccgcagactactttttgatggaa
gaaaaatattttatatctaaagaaaagaatgaatgcagaaaacagccgttccagagggcc
attggtcccgaggaagagatcgtgcagattttaagcagctggtttccagaagagggctat
gttggcaggattgtcttaaaaacccagcaggaaaacctggaagagaaaagcattgttcaa
gatgacagggaggtgatcttgagctcggaggaggagagtttctttgtccaagtgcacgac
gtttctccagagcagccgcggacagtcatcaaagcgccgcgcgtcagcaccgcacaggac
gtcattcagcaaaccttatgcaaagccaagtactcctacagcatcctgagcaaccccaac
ccgaacgactacgtacttttggaagaggtggtgaaagacacagccaacaagaagtcttct
acccccaagtcctcccagcgtgtccttctggatcaggagtgtgtgtttcaagcccaaagc
aagtggaaaggtgcaggaaaattcatccttaaactaaaggagcaggtgcaggcatcccga
gaagacaagagaaaaggcatttcttttgcaagtgaattcaagaagttcaccaagtcaact
aaacagccccgaggactcacatcaccttctcaggtcttggtttcggaaagtgtccaaaac
aaagaggagagacctgtgggtggcagcgacacgatggactatcgacagtga
DBGET
integrated database retrieval system