Myotis daubentonii (Daubenton's bat): 132217928
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Entry
132217928 CDS
T10294
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
mdt Myotis daubentonii (Daubenton's bat)
Pathway
mdt00260
Glycine, serine and threonine metabolism
mdt00630
Glyoxylate and dicarboxylate metabolism
mdt00670
One carbon pool by folate
mdt01100
Metabolic pathways
mdt01200
Carbon metabolism
mdt01230
Biosynthesis of amino acids
mdt01240
Biosynthesis of cofactors
mdt01523
Antifolate resistance
mdt04981
Folate transport and metabolism
Module
mdt_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
mdt00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
132217928 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
132217928 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
132217928 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
132217928 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
132217928 (SHMT1)
Enzymes [BR:
mdt01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
132217928 (SHMT1)
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Gene cluster
GFIT
Motif
Pfam:
SHMT
Aminotran_1_2
DegT_DnrJ_EryC1
DUF6303
Motif
Other DBs
NCBI-GeneID:
132217928
NCBI-ProteinID:
XP_059524392
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Position
16:complement(4030414..4054182)
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AA seq
484 aa
AA seq
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MATAVSRAPKNADLWSSHDRMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFVDELEILCQKRALQVYGLDPQCWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
INYDQLEENARLFHPKLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGV
VPSPFEHCHVVSTTTHKTLRGCRAGMIFYRRGVRSTDPKTGKEILYNLESLINSAVFPGL
QGGPHNHAIAGVAVALKQAMTPEFRVYQQQVVANCRALAEALTELGYKIVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLETEFQK
VAHFIHKGIELTLQIQKDVGDKASLKEFKEKLAGDERHRGAVRALREEVESFASLFPLPG
LPDF
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atggcgaccgcggtgagcagggctcccaagaacgctgacctgtggtcctcgcatgacaga
atgctggcgcagcccctgaaagacagcgacgtcgaggtttacaacatcattaagaaggag
agtaaccggcagagggttggactagagctgatcgcctcagagaattttgccagccgagca
gttttggaggccctgggctcctgcttaaataacaagtactctgaggggtaccctggccag
aggtattacggcgggactgagtttgttgatgagctggagatcctctgtcagaagcgagcg
ctgcaggtctacggtctggacccccagtgctggggggtcaacgtccagccctactcgggc
tcccctgccaacttcgcagtgtacaccgccctggtggaaccccacgggcgcatcatgggc
ctggacctgcccgacggaggtcacctgacccacgggttcatgacggacaagaagaaaatc
tctgctacatccatcttttttgaatctatgccctataaggtgaaccccgacactggctac
atcaactacgaccagctggaggaaaacgcccgcctcttccacccgaagctcattatcgca
ggaaccagctgctactcccgaaacctggactacgctcgactgcggaagattgccgatgac
aacggggcgtatctcatggccgacatggcgcacatcagcgggctggtggcggctggcgtg
gtgccctcccccttcgagcactgccacgtggtgtccaccaccacccacaagaccctgcga
ggctgccgcgcgggcatgatcttctacaggcgaggagtgcgcagcacggaccccaaaacc
ggcaaagagattctgtacaacctggagtcgctcatcaactctgctgtgttcccagggctg
cagggcgggccccacaaccacgccattgctggggtggccgtggctctgaagcaggccatg
actccagagttccgggtgtaccagcagcaggtggtggccaactgcagggcgctggctgag
gccctgacggagctgggctacaaaatagtaacaggtggttctgacaaccatttgatcctc
gtggatctccgttccaaaggcacagatggtggccgggctgagaaggtgctagaagcctgt
tctattgcttgcaacaagaacacctgcccaggtgacagaagcgccctgcggcccagtgga
ctgcgactggggaccccagcactgacgtcccgaggacttctggaaacagagttccagaaa
gtagcccactttattcacaaagggatagaactgactctgcagattcagaaggacgttggg
gacaaggccagcctgaaggagttcaaggagaagctagcgggggatgagcggcaccgtggg
gccgtccgagccctccgggaggaggtggagagcttcgcgtctctcttccctctgcccggc
ctgccggacttttag
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