KEGG   Myotis daubentonii (Daubenton's bat): 132219031
Entry
132219031         CDS       T10294                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
mdt  Myotis daubentonii (Daubenton's bat)
Pathway
mdt04010  MAPK signaling pathway
mdt04015  Rap1 signaling pathway
mdt04218  Cellular senescence
mdt04380  Osteoclast differentiation
mdt04620  Toll-like receptor signaling pathway
mdt04664  Fc epsilon RI signaling pathway
mdt04668  TNF signaling pathway
mdt04750  Inflammatory mediator regulation of TRP channels
mdt04912  GnRH signaling pathway
mdt04935  Growth hormone synthesis, secretion and action
mdt04936  Alcoholic liver disease
mdt05014  Amyotrophic lateral sclerosis
mdt05022  Pathways of neurodegeneration - multiple diseases
mdt05132  Salmonella infection
mdt05135  Yersinia infection
mdt05145  Toxoplasmosis
mdt05161  Hepatitis B
mdt05163  Human cytomegalovirus infection
mdt05167  Kaposi sarcoma-associated herpesvirus infection
mdt05169  Epstein-Barr virus infection
mdt05170  Human immunodeficiency virus 1 infection
mdt05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mdt05417  Lipid and atherosclerosis
mdt05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mdt00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    132219031 (MAP2K6)
   04015 Rap1 signaling pathway
    132219031 (MAP2K6)
   04668 TNF signaling pathway
    132219031 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    132219031 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    132219031 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    132219031 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    132219031 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    132219031 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    132219031 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    132219031 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    132219031 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    132219031 (MAP2K6)
   05161 Hepatitis B
    132219031 (MAP2K6)
   05163 Human cytomegalovirus infection
    132219031 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    132219031 (MAP2K6)
   05169 Epstein-Barr virus infection
    132219031 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    132219031 (MAP2K6)
   05135 Yersinia infection
    132219031 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    132219031 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    132219031 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    132219031 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    132219031 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    132219031 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    132219031 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mdt01001]
    132219031 (MAP2K6)
Enzymes [BR:mdt01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     132219031 (MAP2K6)
Protein kinases [BR:mdt01001]
 Serine/threonine kinases: STE group
  STE7 family
   132219031 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Haspin_kinase Choline_kinase DUF4344 APH
Other DBs
NCBI-GeneID: 132219031
NCBI-ProteinID: XP_059527013
LinkDB
Position
16:50660531..50778696
AA seq 278 aa
MELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFTVTFY
GALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVI
HRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSV
KSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLK
KNSKERPTYPELMQHPFFTLHESKATDVASFVKLIIGD
NT seq 837 nt   +upstreamnt  +downstreamnt
atggagctgggccgaggtgcgtacggagtggtggagaagatgagacatgtgcccagcggg
cagatcatggcagtgaagcggatccgggccaccgtgaacagccaggagcagaaaaggcta
ctgatggacctggatgtctccatgaggacggtggactgtccctttacggtcaccttttac
ggcgcgctcttccgggagggtgatgtttggatctgcatggagctcatggatacgtcacta
gataaattctacaaacaagtgattgataaaggccaaaccattccagaggacatcttaggg
aaaatagcagtttctattgttaaagctttagagcatttacacagtaagctctctgtcatc
catcgagacgtcaagccttccaacgtgctcatcaatgctctgggccaagtgaagatgtgc
gactttggcatcagtggctaccttgtggactcggtggctaaaactatcgatgctggatgc
aaaccgtacatggctccggaaaggataaacccggagctcaaccagaagggctacagtgtg
aagtctgacatttggagcctgggcatcaccatgattgagttggccatccttcggtttccc
tacgattcatggggaactcctttccagcagctcaaacaggtggtggaggagccgtcacca
cagctgcccgcagacaagttctccgaagagtttgtcgactttacctcgcagtgcttgaag
aagaattccaaagaacggccaacatatccagagcttatgcaacatccgtttttcactcta
catgaatccaaagcaacagacgtggcatcttttgtaaaattgattattggagactaa

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