KEGG   Myotis daubentonii (Daubenton's bat): 132222407
Entry
132222407         CDS       T10294                                 
Symbol
AKT3
Name
(RefSeq) RAC-gamma serine/threonine-protein kinase isoform X1
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
mdt  Myotis daubentonii (Daubenton's bat)
Pathway
mdt01521  EGFR tyrosine kinase inhibitor resistance
mdt01522  Endocrine resistance
mdt01524  Platinum drug resistance
mdt04010  MAPK signaling pathway
mdt04012  ErbB signaling pathway
mdt04014  Ras signaling pathway
mdt04015  Rap1 signaling pathway
mdt04022  cGMP-PKG signaling pathway
mdt04024  cAMP signaling pathway
mdt04062  Chemokine signaling pathway
mdt04066  HIF-1 signaling pathway
mdt04068  FoxO signaling pathway
mdt04071  Sphingolipid signaling pathway
mdt04072  Phospholipase D signaling pathway
mdt04140  Autophagy - animal
mdt04150  mTOR signaling pathway
mdt04151  PI3K-Akt signaling pathway
mdt04152  AMPK signaling pathway
mdt04210  Apoptosis
mdt04211  Longevity regulating pathway
mdt04213  Longevity regulating pathway - multiple species
mdt04218  Cellular senescence
mdt04261  Adrenergic signaling in cardiomyocytes
mdt04370  VEGF signaling pathway
mdt04371  Apelin signaling pathway
mdt04380  Osteoclast differentiation
mdt04510  Focal adhesion
mdt04550  Signaling pathways regulating pluripotency of stem cells
mdt04611  Platelet activation
mdt04613  Neutrophil extracellular trap formation
mdt04620  Toll-like receptor signaling pathway
mdt04625  C-type lectin receptor signaling pathway
mdt04630  JAK-STAT signaling pathway
mdt04660  T cell receptor signaling pathway
mdt04662  B cell receptor signaling pathway
mdt04664  Fc epsilon RI signaling pathway
mdt04666  Fc gamma R-mediated phagocytosis
mdt04668  TNF signaling pathway
mdt04722  Neurotrophin signaling pathway
mdt04725  Cholinergic synapse
mdt04728  Dopaminergic synapse
mdt04810  Regulation of actin cytoskeleton
mdt04910  Insulin signaling pathway
mdt04914  Progesterone-mediated oocyte maturation
mdt04915  Estrogen signaling pathway
mdt04917  Prolactin signaling pathway
mdt04919  Thyroid hormone signaling pathway
mdt04920  Adipocytokine signaling pathway
mdt04922  Glucagon signaling pathway
mdt04923  Regulation of lipolysis in adipocytes
mdt04926  Relaxin signaling pathway
mdt04929  GnRH secretion
mdt04931  Insulin resistance
mdt04932  Non-alcoholic fatty liver disease
mdt04933  AGE-RAGE signaling pathway in diabetic complications
mdt04935  Growth hormone synthesis, secretion and action
mdt04936  Alcoholic liver disease
mdt04973  Carbohydrate digestion and absorption
mdt05010  Alzheimer disease
mdt05017  Spinocerebellar ataxia
mdt05132  Salmonella infection
mdt05135  Yersinia infection
mdt05142  Chagas disease
mdt05145  Toxoplasmosis
mdt05152  Tuberculosis
mdt05160  Hepatitis C
mdt05161  Hepatitis B
mdt05162  Measles
mdt05163  Human cytomegalovirus infection
mdt05164  Influenza A
mdt05165  Human papillomavirus infection
mdt05166  Human T-cell leukemia virus 1 infection
mdt05167  Kaposi sarcoma-associated herpesvirus infection
mdt05168  Herpes simplex virus 1 infection
mdt05169  Epstein-Barr virus infection
mdt05170  Human immunodeficiency virus 1 infection
mdt05200  Pathways in cancer
mdt05205  Proteoglycans in cancer
mdt05207  Chemical carcinogenesis - receptor activation
mdt05208  Chemical carcinogenesis - reactive oxygen species
mdt05210  Colorectal cancer
mdt05211  Renal cell carcinoma
mdt05212  Pancreatic cancer
mdt05213  Endometrial cancer
mdt05214  Glioma
mdt05215  Prostate cancer
mdt05218  Melanoma
mdt05220  Chronic myeloid leukemia
mdt05221  Acute myeloid leukemia
mdt05222  Small cell lung cancer
mdt05223  Non-small cell lung cancer
mdt05224  Breast cancer
mdt05225  Hepatocellular carcinoma
mdt05226  Gastric cancer
mdt05230  Central carbon metabolism in cancer
mdt05231  Choline metabolism in cancer
mdt05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mdt05415  Diabetic cardiomyopathy
mdt05417  Lipid and atherosclerosis
mdt05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mdt00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    132222407 (AKT3)
   04012 ErbB signaling pathway
    132222407 (AKT3)
   04014 Ras signaling pathway
    132222407 (AKT3)
   04015 Rap1 signaling pathway
    132222407 (AKT3)
   04370 VEGF signaling pathway
    132222407 (AKT3)
   04371 Apelin signaling pathway
    132222407 (AKT3)
   04630 JAK-STAT signaling pathway
    132222407 (AKT3)
   04668 TNF signaling pathway
    132222407 (AKT3)
   04066 HIF-1 signaling pathway
    132222407 (AKT3)
   04068 FoxO signaling pathway
    132222407 (AKT3)
   04072 Phospholipase D signaling pathway
    132222407 (AKT3)
   04071 Sphingolipid signaling pathway
    132222407 (AKT3)
   04024 cAMP signaling pathway
    132222407 (AKT3)
   04022 cGMP-PKG signaling pathway
    132222407 (AKT3)
   04151 PI3K-Akt signaling pathway
    132222407 (AKT3)
   04152 AMPK signaling pathway
    132222407 (AKT3)
   04150 mTOR signaling pathway
    132222407 (AKT3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    132222407 (AKT3)
  09143 Cell growth and death
   04210 Apoptosis
    132222407 (AKT3)
   04218 Cellular senescence
    132222407 (AKT3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    132222407 (AKT3)
   04550 Signaling pathways regulating pluripotency of stem cells
    132222407 (AKT3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    132222407 (AKT3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    132222407 (AKT3)
   04613 Neutrophil extracellular trap formation
    132222407 (AKT3)
   04620 Toll-like receptor signaling pathway
    132222407 (AKT3)
   04625 C-type lectin receptor signaling pathway
    132222407 (AKT3)
   04660 T cell receptor signaling pathway
    132222407 (AKT3)
   04662 B cell receptor signaling pathway
    132222407 (AKT3)
   04664 Fc epsilon RI signaling pathway
    132222407 (AKT3)
   04666 Fc gamma R-mediated phagocytosis
    132222407 (AKT3)
   04062 Chemokine signaling pathway
    132222407 (AKT3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    132222407 (AKT3)
   04922 Glucagon signaling pathway
    132222407 (AKT3)
   04923 Regulation of lipolysis in adipocytes
    132222407 (AKT3)
   04920 Adipocytokine signaling pathway
    132222407 (AKT3)
   04929 GnRH secretion
    132222407 (AKT3)
   04915 Estrogen signaling pathway
    132222407 (AKT3)
   04914 Progesterone-mediated oocyte maturation
    132222407 (AKT3)
   04917 Prolactin signaling pathway
    132222407 (AKT3)
   04926 Relaxin signaling pathway
    132222407 (AKT3)
   04935 Growth hormone synthesis, secretion and action
    132222407 (AKT3)
   04919 Thyroid hormone signaling pathway
    132222407 (AKT3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    132222407 (AKT3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    132222407 (AKT3)
  09156 Nervous system
   04725 Cholinergic synapse
    132222407 (AKT3)
   04728 Dopaminergic synapse
    132222407 (AKT3)
   04722 Neurotrophin signaling pathway
    132222407 (AKT3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    132222407 (AKT3)
  09149 Aging
   04211 Longevity regulating pathway
    132222407 (AKT3)
   04213 Longevity regulating pathway - multiple species
    132222407 (AKT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    132222407 (AKT3)
   05205 Proteoglycans in cancer
    132222407 (AKT3)
   05207 Chemical carcinogenesis - receptor activation
    132222407 (AKT3)
   05208 Chemical carcinogenesis - reactive oxygen species
    132222407 (AKT3)
   05230 Central carbon metabolism in cancer
    132222407 (AKT3)
   05231 Choline metabolism in cancer
    132222407 (AKT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    132222407 (AKT3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    132222407 (AKT3)
   05212 Pancreatic cancer
    132222407 (AKT3)
   05225 Hepatocellular carcinoma
    132222407 (AKT3)
   05226 Gastric cancer
    132222407 (AKT3)
   05214 Glioma
    132222407 (AKT3)
   05221 Acute myeloid leukemia
    132222407 (AKT3)
   05220 Chronic myeloid leukemia
    132222407 (AKT3)
   05218 Melanoma
    132222407 (AKT3)
   05211 Renal cell carcinoma
    132222407 (AKT3)
   05215 Prostate cancer
    132222407 (AKT3)
   05213 Endometrial cancer
    132222407 (AKT3)
   05224 Breast cancer
    132222407 (AKT3)
   05222 Small cell lung cancer
    132222407 (AKT3)
   05223 Non-small cell lung cancer
    132222407 (AKT3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    132222407 (AKT3)
   05170 Human immunodeficiency virus 1 infection
    132222407 (AKT3)
   05161 Hepatitis B
    132222407 (AKT3)
   05160 Hepatitis C
    132222407 (AKT3)
   05164 Influenza A
    132222407 (AKT3)
   05162 Measles
    132222407 (AKT3)
   05168 Herpes simplex virus 1 infection
    132222407 (AKT3)
   05163 Human cytomegalovirus infection
    132222407 (AKT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    132222407 (AKT3)
   05169 Epstein-Barr virus infection
    132222407 (AKT3)
   05165 Human papillomavirus infection
    132222407 (AKT3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    132222407 (AKT3)
   05135 Yersinia infection
    132222407 (AKT3)
   05152 Tuberculosis
    132222407 (AKT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    132222407 (AKT3)
   05142 Chagas disease
    132222407 (AKT3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    132222407 (AKT3)
   05017 Spinocerebellar ataxia
    132222407 (AKT3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    132222407 (AKT3)
   05418 Fluid shear stress and atherosclerosis
    132222407 (AKT3)
   05415 Diabetic cardiomyopathy
    132222407 (AKT3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    132222407 (AKT3)
   04932 Non-alcoholic fatty liver disease
    132222407 (AKT3)
   04931 Insulin resistance
    132222407 (AKT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    132222407 (AKT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    132222407 (AKT3)
   01524 Platinum drug resistance
    132222407 (AKT3)
   01522 Endocrine resistance
    132222407 (AKT3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mdt01001]
    132222407 (AKT3)
Enzymes [BR:mdt01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     132222407 (AKT3)
Protein kinases [BR:mdt01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   132222407 (AKT3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like PH_20 PH_11 ABC1 DUF6932
Other DBs
NCBI-GeneID: 132222407
NCBI-ProteinID: XP_059533328
LinkDB
Position
20:complement(12624848..12834906)
AA seq 477 aa
MSDVTIVKEGWVQKRGEYIKNWRPRYFILKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMSCC
SPTSQIDNIGEEEMDASATHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKIL
KKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSR
ERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITD
TATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELIL
MEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDSKEIMRHSFFSGVNWQDVYDKKLV
PPFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDNESRPHFPQFSYSASGRE
NT seq 1434 nt   +upstreamnt  +downstreamnt
atgagcgatgtgaccattgtgaaagaaggttgggttcagaagaggggcgaatatataaaa
aactggaggccacgatatttcattttgaagacagatggctcattcataggatataaagag
aaacctcaagacgtggacctgccttaccccctcaacaacttctcagtggcaaaatgccag
ttaatgaaaacagaacgaccaaagccaaacacattcattatcagatgtctccagtggacc
actgtaatagagagaacctttcatgtagatacgccagaggaaagggaagaatggacggaa
gctattcaggccgtagcagacagactccagaggcaagaggaggagaggatgagttgttgc
agtccaacctcacaaattgataatataggggaggaggagatggatgcttctgcaacccat
cataaaagaaagacaatgaatgattttgactatttgaaactactaggtaaaggcactttt
gggaaagttattttggttcgagagaaggcaagtgggaagtattatgctatgaagattctg
aagaaagaagttattattgcaaaggatgaagtggctcacaccctcacggagagccgggta
ttgaagaacacgaggcatcccttcttgacatccttgaaatattccttccagacaaaagac
cgtttgtgttttgtgatggaatatgtcaatgggggcgagctgtttttccatttgtcgaga
gagcgggtgttctccgaggaccgcacgcgcttctacggcgcggagatcgtctcggccctg
gactacctgcactcggggaagatcgtgtaccgggacctgaagttggagaatttgatgctg
gataaagatggccacataaaaatcacagattttggactttgcaaagaggggatcacagac
acggccaccatgaagaccttctgtggaaccccggagtacctggcgccagaggtgttggag
gacaacgactacggccgggctgtggactggtggggcctgggggtcgtcatgtatgagatg
atgtgcggcaggctgcctttctacaaccaggaccacgagaagctgttcgaactgatcctg
atggaagacatcaagttccctcgcacactctcctccgatgcaaaatcactgctttcaggg
ctcttgataaaggatccaaataaacgccttggcgggggaccagatgattcaaaagaaatt
atgagacacagtttcttctctggagtaaactggcaagatgtatatgataaaaagcttgta
cctccttttaagcctcaagtaacatctgagacagataccagatattttgatgaagaattt
acagctcagactattacaataacaccacctgaaaaatatgacgaggacggcatggacaac
gagagccggccgcacttccctcagttctcctactcggcgagcggccgcgagtag

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