Myotis daubentonii (Daubenton's bat): 132232932 Help Entry 132232932         CDS       T10294                                  Symbol TSC2 Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism mdt  Myotis daubentonii (Daubenton's bat) Pathway mdt04072   Phospholipase D signaling pathway mdt04115   p53 signaling pathway mdt04140   Autophagy - animal mdt04150   mTOR signaling pathway mdt04151   PI3K-Akt signaling pathway mdt04152   AMPK signaling pathway mdt04211   Longevity regulating pathway mdt04218   Cellular senescence mdt04714   Thermogenesis mdt04910   Insulin signaling pathway mdt04919   Thyroid hormone signaling pathway mdt05163   Human cytomegalovirus infection mdt05165   Human papillomavirus infection mdt05168   Herpes simplex virus 1 infection mdt05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:mdt00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     132232932 (TSC2)    04151 PI3K-Akt signaling pathway     132232932 (TSC2)    04152 AMPK signaling pathway     132232932 (TSC2)    04150 mTOR signaling pathway     132232932 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     132232932 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     132232932 (TSC2)    04218 Cellular senescence     132232932 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     132232932 (TSC2)    04919 Thyroid hormone signaling pathway     132232932 (TSC2)   09149 Aging    04211 Longevity regulating pathway     132232932 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     132232932 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     132232932 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     132232932 (TSC2)    05163 Human cytomegalovirus infection     132232932 (TSC2)    05165 Human papillomavirus infection     132232932 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:mdt01009]     132232932 (TSC2) Protein phosphatases and associated proteins [BR:mdt01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      132232932 (TSC2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 Motif Other DBs NCBI-GeneID:  132232932 NCBI-ProteinID:  XP_059548719 LinkDB All DBs Position 4:14291707..14328537 Genome browser AA seq 1786 aa AA seqDB search MAKPTSKDSGLREKFKILLGLGTSRPNPRSAEGKQTEFVITADILRELSVECGLNNRIRV IGQICEVAKTKKFEDHAVEALWKAVADLLQPERPPEARHAVLALLKAIVQGQGDRLGVLR ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELAEFVLQWMDIGLSSEFLLVL VNLVKFNSCYLDEYIASMVHMICLLCVQTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRAYMEDAPLLRGAVFFVG MALWGAHRLHSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYKRELQAVTWDI LLNIIERLLQQLQSLESPELRAIVHDLLTTVEELCDQNEFHGSQERYFELIERCADQRPE SSLLNLITYRAQSIHPAKVGWIHNLQLLMEKFFRSESRSAVRIKVLDVLSFVLLINRQFY EEELINTVVISQLSHIPEDRDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVIARSLS PPPELEERDMAAYSASLEDVKTAVLGLLVILQTKLYTLPASHALRVYEMLVSHIQLHYKH SYTLPIASSIRLQAFDFLLLLRADSLHRLGLPTKDGVVRFSPYCLCDYMEVERGSEKKAG GPLSPPTGLSGPASAGPAVRLGSLPYSLVFGVLLQCLKQETDWKVLKLVLSKLPESLRYK VLIFTSPCSVDQLSSALCAMLSGPKTLERLRGTPEGFSRTDLYLAVVPVLTALISYHNYL DKLRQREMVYCLEQGLIFRCASQCVVALAICSVEMPDIMIKALPVLVVKLTHISATASMA IPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPFITKGLRSNVLRSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNS PPVKEFKESSAAEAFRCRSISVSEHVVRSRIQTSLTSSSLGSADENSMAQADDNLKNLHL ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLITVTTSVGTGTRSL LGLDSGELEGSPELSSDLSMHRRQTKEAPAKLESQAGQQVCLGARDRVRSMSGGHGLRIG ALDTPASHFPGSPAFPGPQTAPASKPEKASASTQRPVQKEKTNLAAYVPLLTQGWAEILV RRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKERRDTALYKSLSVPAAS SAKPSPPPRSNTDSAVVLEEGSPDEANLLPPELEDFEATLGTDRRCRHAEAYSRSSSTSS QEEKSFHAEELSAGGIPIERAVSSEAARPSVDLSFQPSQPLSKSSSSPELQTLQDILGDP GNKADVGRLSPEAKARSQSGILDGEGTAWSAPGEASRGPSHAEGPMPSGCPRSPSGLRPR GYTISDSAPSRRGKRVERDSFKSRAGAANAEKVPGINPSFVFLQLYHSPFFGDESNKPIL LPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGKL IELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHL GNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITPLDYECNLVSLQCRKDMEGLVDTSVAK IVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRHRIREEAHYS NPSLPLMHPTGHAKAPAQAPAEPMPTYETGQRKRLISSVDDFTEFV NT seq 5361 nt NT seq  +upstreamnt  +downstreamnt atggccaagccaacaagcaaagattcaggcttgagggagaagttcaagattctgttggga ctgggaacttcaagaccaaatcccaggtctgcagagggcaaacagacggagtttgtcatc acagcggacatcctgcgagaactgagtgttgaatgtggcctcaacaatcgcattcgggtg atagggcagatctgtgaagtcgcaaaaacgaaaaaatttgaagaccatgcagtggaagca ctctggaaggcagtggctgacctgctgcagccggaacggccaccagaggcccgccacgca gtactggctctcctgaaggccatcgtgcagggacagggggatcgcttgggtgtgctcagg gccctcttcttcaaggtcatcaaggattacccctccaacgaagacctccacgaaagactg gaagttttcaaggcccttacggataatgggagacacattacctacttggaagaagagctg gctgagtttgtcctgcagtggatggatattggcctgtcctcagaattccttctggtgctt gtgaacctggtcaaattcaacagctgttacctcgatgaatatattgcatcaatggtccac atgatctgcctgctgtgtgtgcagactgtgtcctccgtggacatagaggtgtctctgcag gtgctggatgccgtggtctgctacaactgcctgccagccgagagcctccccctctttatt gtcactctctgtcgcaccatcaatgtcaaggagctctgtgagccttgctggaagttgatg cgtaaccttctgggcacccacctgggccacagtgctatctataacatgtgtcgcatcatg gaggacagagcctacatggaagatgccccgctgctgagaggagctgtgttctttgttggc atggctctctggggagcccaccgactccattctctcaagaactccccgacatctgtgctg ccatcattttatgaggccatgacctgtccaaacgaggtggtgtcctatgagatcgtcctc tctataaccaggctcatcaagaagtacaagagggagctccaggctgtgacgtgggacatt ctgctgaacattatcgagcgcctgcttcagcagcttcagagcctggagagcccagagctc agagccattgtccatgacctgctgaccacagtggaagagctatgtgatcagaacgagttc catggctcacaggagagatactttgagctcattgagagatgtgcagaccaaagacctgag tcctccctcttaaacttaataacctacagggctcagtcaatccacccagcgaaggttggc tggattcacaacctgcagttactgatggagaaattcttcaggagtgaatctcgcagtgcc gtgcgcatcaaggtgctggacgtcctgtccttcgtgctgctcatcaacaggcagttctat gaggaggagctgatcaacacggtggtcatctcacagctctcccacatccctgaggacaga gaccaccaggtccggaagttggccacccagttgctggtggacctggccgaaggctgccac acccaccacttcaacagcctgctggacatcattgagaaagtgattgcccgctccctctct ccgcccccagagctggaggaaagagacatggcggcatactctgcctccttggaggacgtg aagactgctgtcctggggctgctagtcatccttcagaccaagctgtataccttgcctgcc agccacgctctgcgtgtgtacgagatgctcgtcagtcacatccagctccactataagcac agctataccctgcccattgccagcagcatccggctgcaggccttcgacttcctgctgctg ctgcgggccgactcgctgcatcgcctcggcctgcccaccaaggatggcgtggtgcggttc agcccctactgcctctgtgactacatggaggtagagagaggctctgagaagaaggccggt ggccccctgtcccctcccaccgggctgtctggcccagcatctgcaggccccgccgttcgg cttggctctctgccctactccctggtcttcggagtcctcctgcagtgtttgaagcaggag actgactggaaggtgctgaagcttgtgctcagcaagctgcctgagtcgctgcgttacaag gtcctcattttcacctctccatgcagcgttgaccagctgtcttctgctctgtgcgccatg ctttcaggtcccaagaccctcgaacgacttcgaggcaccccagaagggttctccagaact gacctatatctggctgtggttcctgtgctgacagcattgatctcttaccataactacttg gacaaactcagacagcgggagatggtgtactgcctggagcaaggcctcatcttccgctgc gccagccagtgtgtggtggccctggccatctgcagcgtggagatgcccgacatcatgatc aaagctctgcccgtcctggttgtgaagctcacacacatctcggccacagctagtatggcc attccacttcttgagttcctgtcaactctggccaggctgcctcatctctacaggaacttc gcagcagagcagtacgcgagcgtgtttgccatctccctgccatataccaacccttccaag ttcaaccagtacattgtgtgcctggcccatcatgtcatagctatgtggttcattaggtgc cgcctgcccttccggaaagactttgttccttttatcacgaagggcctgcgctccaacgtc ctccggtcttttgatgatacccctgagaaggacagcttcagagcacggagcaccagtctc aacgagaggcccaagagtttgaggatagccagaccccccaaacaaggcttgaataactct ccacccgtcaaagaattcaaggagagctctgcagccgaggccttccggtgccgcagcatc agtgtgtctgaacatgtggtccgcagcaggatccagacgtccctcacgagctccagcttg gggtctgcagatgagaactcgatggcccaggccgatgacaacttgaaaaatctccacttg gagctcacagaaacgtgtctggatatgatggccagatacgtgttctccaacttcaccgcc gtcccgaagaggtcccctgtgggagagtttctcctggccggaggtaggaccaaaacctgg ctggttgggaataagcttatcaccgtgacaactagtgtggggactggaacccggtcgctt ctgggcctggactctggagaactggagggcagtccagagttgagctctgacctcagcatg cacaggagacagacaaaggaggcaccagccaaactggagtcccaggctgggcagcaggtg tgcctcggggcccgggaccgggttcgctccatgtctgggggccacggccttcgcattggt gccctggacactccagcctcccacttcccaggcagccctgctttcccgggtccacagact gcaccagccagcaagcctgagaaggcctcggccagcacccagcgcccggtgcagaaggag aagaccaacctggcggcctatgtgcccctgctgacccagggctgggcagagatcttggtc cggaggcccacagggaataccagctggctgatgagcctggagaacccgctcagccccttt tcctcggacatcaacaacatgccactgcaggagctgtccaatgccctcatggccgcagag cgcttcaaggagcgccgcgacacggccctgtacaagtcactgtcagtgccggcagccagc tcagccaagccttccccacccccacggtctaacacagactctgctgtggttcttgaggag ggaagtccagacgaggctaatttgctgcccccagaactggaggactttgaggcaacacta ggcacagacaggcgctgtcggcacgctgaggcttacagcaggtcatcttcaacctctagc caggaggagaagtcattccacgcagaggagctgtctgctgggggaatccccatcgagcgg gctgtctcctccgaggcagcccggccctccgtggacctctccttccagccctcacagccc ctgagcaagtccagctcctctcctgaactgcagaccctgcaggacatcctcggggaccct gggaacaaggctgatgttggccggctgagccctgaggctaaggctcggtcacagtcaggg atcctcgatggggaaggcactgcctggtcagccccaggcgaagccagccggggcccctcc cacgccgagggtcccatgccttccggctgtccccgctcccccagtggcctgcggccccga ggctacaccatctctgattcggccccgtcacgcaggggcaagagggtggagagggactcc ttcaaaagcagagcaggagccgccaatgccgagaaggtgccagggatcaatcccagcttt gtgttcctacagctctaccattcgcctttctttggtgacgagtccaacaagccaatcctt ttgcccaatgagtctttcgagcggtcagtgcagctcctcgaccagatcccatcatatgac acgcacaagattgccgtcctgtacgtgggagaaggccagagcaatagtgaactcgccatc ctgtccaacgagcatggctcctacaggtacacggagttcctgacaggcctgggcaagctc atcgagctcaaggactgtcagccggataaggtgtacctaggtggcctggacgtgtgtggc gaggacggccagtttacctactgctggcatgatgacatcatgcaagctgtcttccacatt gccaccctgatgcccaccaaggacgtagacaagcaccgctgtgacaagaagcgccacctg ggcaacgactttgtgtccattgtctacaatgactctggcgaggacttcaagctgggtacc atcaaaggccagttcaacttcgtccatgtgatcatcacccccctggactacgagtgcaac ctggtgtcgctgcagtgcaggaaagacatggagggccttgtggacaccagcgtggccaag attgtgtctgaccgcaacctgcccttcgtggcccgccagatggccctacatgcaaatatg gcctcacaggtgcaccacagccgctccaaccccactgacatctatccctccaagtggatc gccaggctccgccacatcaagaggctccgccaccggatccgtgaggaagcccactactcg aaccccagcctgcccctgatgcaccccacgggccatgccaaagccccagcacaggccccc gccgagcccatgcccacctatgagacaggccagcggaagcgcctcatctcctccgtggat gacttcacagagttcgtgtga

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