Myotis daubentonii (Daubenton's bat): 132234986
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Entry
132234986 CDS
T10294
Symbol
SOS2
Name
(RefSeq) son of sevenless homolog 2 isoform X1
KO
K03099
son of sevenless
Organism
mdt Myotis daubentonii (Daubenton's bat)
Pathway
mdt01521
EGFR tyrosine kinase inhibitor resistance
mdt01522
Endocrine resistance
mdt04010
MAPK signaling pathway
mdt04012
ErbB signaling pathway
mdt04014
Ras signaling pathway
mdt04062
Chemokine signaling pathway
mdt04068
FoxO signaling pathway
mdt04072
Phospholipase D signaling pathway
mdt04150
mTOR signaling pathway
mdt04151
PI3K-Akt signaling pathway
mdt04510
Focal adhesion
mdt04540
Gap junction
mdt04630
JAK-STAT signaling pathway
mdt04650
Natural killer cell mediated cytotoxicity
mdt04660
T cell receptor signaling pathway
mdt04662
B cell receptor signaling pathway
mdt04664
Fc epsilon RI signaling pathway
mdt04714
Thermogenesis
mdt04722
Neurotrophin signaling pathway
mdt04810
Regulation of actin cytoskeleton
mdt04910
Insulin signaling pathway
mdt04912
GnRH signaling pathway
mdt04915
Estrogen signaling pathway
mdt04917
Prolactin signaling pathway
mdt04926
Relaxin signaling pathway
mdt04935
Growth hormone synthesis, secretion and action
mdt05034
Alcoholism
mdt05160
Hepatitis C
mdt05161
Hepatitis B
mdt05163
Human cytomegalovirus infection
mdt05165
Human papillomavirus infection
mdt05200
Pathways in cancer
mdt05205
Proteoglycans in cancer
mdt05206
MicroRNAs in cancer
mdt05207
Chemical carcinogenesis - receptor activation
mdt05208
Chemical carcinogenesis - reactive oxygen species
mdt05210
Colorectal cancer
mdt05211
Renal cell carcinoma
mdt05213
Endometrial cancer
mdt05214
Glioma
mdt05215
Prostate cancer
mdt05220
Chronic myeloid leukemia
mdt05221
Acute myeloid leukemia
mdt05223
Non-small cell lung cancer
mdt05224
Breast cancer
mdt05225
Hepatocellular carcinoma
mdt05226
Gastric cancer
mdt05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mdt00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
132234986 (SOS2)
04012 ErbB signaling pathway
132234986 (SOS2)
04014 Ras signaling pathway
132234986 (SOS2)
04630 JAK-STAT signaling pathway
132234986 (SOS2)
04068 FoxO signaling pathway
132234986 (SOS2)
04072 Phospholipase D signaling pathway
132234986 (SOS2)
04151 PI3K-Akt signaling pathway
132234986 (SOS2)
04150 mTOR signaling pathway
132234986 (SOS2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
132234986 (SOS2)
04540 Gap junction
132234986 (SOS2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
132234986 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
132234986 (SOS2)
04660 T cell receptor signaling pathway
132234986 (SOS2)
04662 B cell receptor signaling pathway
132234986 (SOS2)
04664 Fc epsilon RI signaling pathway
132234986 (SOS2)
04062 Chemokine signaling pathway
132234986 (SOS2)
09152 Endocrine system
04910 Insulin signaling pathway
132234986 (SOS2)
04912 GnRH signaling pathway
132234986 (SOS2)
04915 Estrogen signaling pathway
132234986 (SOS2)
04917 Prolactin signaling pathway
132234986 (SOS2)
04926 Relaxin signaling pathway
132234986 (SOS2)
04935 Growth hormone synthesis, secretion and action
132234986 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
132234986 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
132234986 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
132234986 (SOS2)
05206 MicroRNAs in cancer
132234986 (SOS2)
05205 Proteoglycans in cancer
132234986 (SOS2)
05207 Chemical carcinogenesis - receptor activation
132234986 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
132234986 (SOS2)
05231 Choline metabolism in cancer
132234986 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
132234986 (SOS2)
05225 Hepatocellular carcinoma
132234986 (SOS2)
05226 Gastric cancer
132234986 (SOS2)
05214 Glioma
132234986 (SOS2)
05221 Acute myeloid leukemia
132234986 (SOS2)
05220 Chronic myeloid leukemia
132234986 (SOS2)
05211 Renal cell carcinoma
132234986 (SOS2)
05215 Prostate cancer
132234986 (SOS2)
05213 Endometrial cancer
132234986 (SOS2)
05224 Breast cancer
132234986 (SOS2)
05223 Non-small cell lung cancer
132234986 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
132234986 (SOS2)
05160 Hepatitis C
132234986 (SOS2)
05163 Human cytomegalovirus infection
132234986 (SOS2)
05165 Human papillomavirus infection
132234986 (SOS2)
09165 Substance dependence
05034 Alcoholism
132234986 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
132234986 (SOS2)
01522 Endocrine resistance
132234986 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
IQ_SEC7_PH
PH_19
RHG20_PH
PH_10
PH_13
Motif
Other DBs
NCBI-GeneID:
132234986
NCBI-ProteinID:
XP_059552650
LinkDB
All DBs
Position
1:41359462..41464494
Genome browser
AA seq
1332 aa
AA seq
DB search
MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDKKLFKPSDI
EKIFSNISDIHELTIKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPKFNEHFSKLMARPAVALHFQSIADGFREAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG
YSSAEYRLKEKFVMRKIQICDKEDTCDYKHAFELVSKEENSIIFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA
AEKGEQPISVDLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIKRKKQAQANGISHNITFENPPPPIEWHISRPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILD
EAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDHDASNSKGNMKSDDDPPAIPPRQPPPPKVKPRVPAPTGALDGPL
HSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDPDWFRDVSTCPNSPN
TPPSTPSPRVPRRCHVLSSSHNNLAHPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPLY
RLPLLENAETPQ
NT seq
3999 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccctacgagttcttcagcgaagagaacagcccgaaatggcgg
ggactgttggtctcggccctgcggaaggttcaggagcaagtacatcccaatctctcagct
aatgaagaatctctctattatattgaagagctgatttttcagctgcttaataaattatgc
atggcccaaccaaggactgttcaagatgtggaggaacgagttcaaaagacctttcctcat
ccaattgataaatgggctattgctgatgcacaatctgccatagagaaacgaaaacgaaga
aatcccctcttactgcctgtggacaaaatccatccgtcactgaaggaagttttaggatac
aaagtggactaccatgtgtccttatatattgtggctgtactagagtatatctcagctgat
attttgaaattggctggtaattatgtttttaatattcgacattatgaaatatctcagcag
gacattaaagtgtcaatgtgtgcagataaggttttgatggacatgtttgatcaggatgac
ataggtttggtttccctttgtgaagatgaacctagttcttcaggtgaattaaactactat
gaccttgtcagaactgaaattgcagaagaaagacagtatctgcgagaactaaatatgatc
ataaaagtgtttcgagaagcctttctttctgacaaaaagctgtttaaaccttctgacatt
gaaaagattttcagtaacatatcagatatacatgagttgacaataaaacttttaggtttg
attgaagacacagttgaaatgactgatgagagcagtcctcaccccttggctggcagctgt
tttgaagatttggcagaagagcaagcatttgatccttatgaaacattatcacaggacatt
ctttcaccaaaatttaatgaacatttcagtaagttgatggccagacctgcagtggctcta
cactttcagtccattgctgatggttttagagaggcagttcgttatgtccttccacgtctt
atgctagtgcctgtgtatcactgttggcactattttgaattattaaagcaattgaaagct
tgtagtgaagaacaagaagatagagaatgtttgaaccaagccattactgctctcatgaat
ctccaaggtagtatggaccgaatttacaagcagtattcacctcgacgccgacctggggat
cctgtttgccctttttataatcgtcaattaagaagcaagcacctggctattaaaaaaatg
aatgaaattcagaaaaacatagatggatgggaaggcaaagatattggacagtgttgtaat
gaattcattatggaaggtccattgacaagaattggtgctaaacacgaacggcatattttt
ctttttgatggcttaatgattagctgcaaacccaatcacagccagtcacgccttccaggt
tacagtagtgcagaatatagattaaaagaaaaatttgtcatgagaaaaatacaaatatgt
gataaagaagatacttgtgactacaaacatgcttttgaattagtatccaaagaggaaaac
agcataatatttgctgctaagtctgctgaagagaaaaataattggatggcagcacttatt
tctcttcattatcgtagtactctagatcgaatgctagattcagtattattgaaagaagaa
aatgagcaaccactgagattaccaagtcctgaagtttatcgttttgtggtaaaagactct
gaggaaaacattgtttttgaagacaacttgcaaagtagaagtggaatccccattattaaa
ggaggaacagtggtgaagttaattgaaaggttaacatatcatatgtatgcagatcccaat
tttgttcgtacttttcttactacatatcgttcattttgtaaaccacaggaattgctaagc
ttactgattgaacgatttgaaattccagagccagaacctactgaggcagataaattggca
gcagagaaaggcgaacaaccaattagtgtagaccttaaaaggtttcgcaaggaatacgtc
caaccagtgcaacttaggatcttaaatgtatttcggcactgggttgaacaccatttttat
gactttgaaagagatttggagttgctcgaaagactagaatccttcatttcaagtgtaaga
gggaaagccatgaagaaatgggtagagtcaattgctaagatcatcaagaggaagaaacaa
gctcaggcaaatggaataagccataatattacctttgaaaatccacctccgccaattgaa
tggcatatcagcagaccaggacagtttgaaacatttgatctcatgacacttcatccaata
gaaattgcacgtcagctgacacttttggaatctgatctctacaggaaagttcaaccttct
gaacttgtagggagtgtatggaccaaagaagataaagaaataaattctccgaatttatta
aaaatgattcgccatactacaaatcttactctctggtttgaaaagtgcattgtggaagca
gaaaattttgaggaacgggtggcagtactaagtagaattatagaaattctgcaagttttt
caagatttgaataatttcaatggtgtattggaaatagtcagtgcagtaaactcagtgtca
gtatacagactagatcatacctttgaggccttgcaggaaagaaaaaggaaaattttggat
gaagctgtggaattaagtcaagatcactttaaaaaatacttagtaaaacttaagtcaatc
aatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaagactgaagaa
gggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg
aaagtggctgaaattactggagaaattcagcagtatcaaaatcaaccttattgcttacgg
attgaaccagaaatgaggcggttctttgaaaaccttaaccccatgggaagtgcttctgaa
aaagagtttacagattatttgttcaacaaatcactagaaattgaaccccgaaactgcaaa
cagccacctcgatttcccaggaaatcaactttctctttaaaatctcctggaataaggcct
aatacaggccgacatggctctacctcaggcactttacgaggtcatccaacaccattagaa
agagaaccatgtaaaataagctttagtcggattgctgaaactgagcttgagtcaacagtg
tcagcaccaacctctccaaatacaccatctactccaccagtatctgcttcttcagacctt
agtgtgtttttagatgtggatctgaacagttcctgtggcagcaatagcatctttgctcca
gttctcttgccacattcaaagtctttcttcagttcgtgtggtagtttacataaactaagt
gaagagccactgattcctcctcctcttcctcctcgaaaaaaatttgatcatgatgcttca
aattccaagggaaatatgaaatctgatgatgacccccctgctattccaccaagacaacct
cctcctccaaaggtaaaacccagagttcctgctcctactggtgcattggatgggcctctg
catagtccaccgccaccaccgccgagagatcctcttcctgatactcctccaccagttccc
cttcggcctccagaacactttataaactgtccatttaatcttcagccacctccactggga
catcttcacagagatccagactggttcagagacgttagcacgtgtccaaattcaccaaac
actcctcctagcacaccctctccaagggtaccacgtcgatgccacgtgctcagttctagt
cacaataatcttgctcatcctcaagctccccctgttccaccacggcagaattcaagccct
cacctaccaaaactgccaccaaagacttacaaacgggagctttcacaccccccattgtat
agactgcctttgctagaaaatgcagaaactcctcaatga
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