Myotis daubentonii (Daubenton's bat): 132237222
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Entry
132237222 CDS
T10294
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
mdt Myotis daubentonii (Daubenton's bat)
Pathway
mdt00270
Cysteine and methionine metabolism
mdt00480
Glutathione metabolism
mdt01100
Metabolic pathways
mdt01240
Biosynthesis of cofactors
mdt04216
Ferroptosis
Module
mdt_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
mdt00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
132237222 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
132237222 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
132237222 (GCLC)
Enzymes [BR:
mdt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
132237222 (GCLC)
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GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
132237222
NCBI-ProteinID:
XP_059557381
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Position
6:77455394..77505278
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AA seq
641 aa
AA seq
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MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKRVQLVLSGEEVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRQRRKEATSLLKENQALCTITSFPRLGCPGFTLPEVKPNPVEGGASRSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINAPIFKDKNTPSPFIETFPEDDEAAKASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDVDCRWGVI
SASVDDRTREERGLEPLKNSNYRISKSRYDSIDSYLSECGEKYNDIDLTIDKEIYEQLMQ
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
QGMFYFRKDICKAGGNAVVDGCGKAQQGAELAAEEHEEYALMSIDTIINGKEGVFPGLIP
ILNSYLENMEVDVDTRCSILNYLKLIKKRASGELMTVAKWMREFIANHPDYKQDSVITDQ
INYSLILKCNQIANELCECPELLGPAFRRVRYSGSKMDSSN
NT seq
1926 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccaaggctcgccgctgagctgggaggagaccaagcgccacgccgac
cacgtgcggcggcacgggatcctccagtttctgcacatctaccacgccgtcaaggaccga
cacaaggacgtgctcaagtggggcgatgaggtggaatacatgttggtgtcttttgatcat
gaaaataagagagtccagttggtcctgtctggagaagaagtccttgaaactctacaagaa
aagggggaaaggacaaacccgaaccaccctacactttggagaccagagtacgggagttac
atgattgaagggacgcctggacagccatacggaggaaccatgtccgagttcaacacagtt
gaagacaatatgagacagcgccggaaggaggcaacttctttattaaaagaaaatcaggct
ctttgcacaataacttcatttcccagattaggctgtcctgggttcacgctgcctgaggtc
aaacccaacccagtcgaaggaggagcttccaggtccctcttctttcctgatgaagcaata
aacaagcacccccgctttagcaccctaaccagaaatatccggcataggagaggagaaaag
gtggtcatcaatgcaccaatatttaaagataagaacacaccgtctccgtttatagaaaca
tttcctgaggatgacgaggcggccaaggcttcaaagccagatcacatctacatggacgcc
atgggatttgggatgggcaattgctgtcttcaggtaacgttccaagcctgcagcatttcc
gaggctagatacctgtatgatcagttggccactatctgcccaattgtcatggctttgagt
gctgcgtctcctttttaccgaggctatgtgtcagacgttgattgtcgctggggcgtgatt
tctgcatctgtagatgatagaactcgggaggagagaggactggagccactgaagaacagt
aactataggattagtaaatcccgatatgattcaatagacagctatctgtctgagtgtggg
gagaagtacaatgacatcgacttgacaatcgataaagaaatctacgagcagctgatgcag
gaaggcattgaccacctcctggcccagcatgttgctcatctctttatcagagacccgctg
actctgtttgaagagaaaatacacctggatgatgccaatgagtctgaccattttgagaac
attcagtccacaaattggcagacaatgagatttaagcctcctcctccaaactcagacatt
ggatggagagtggagttccggcccatggaggttcagttaacagacttcgagaactcggcg
tatgtggtgtttgtggtgctgctcacgagagtgatcctttcctacaagttagattttctc
attccgctgtcaaaggttgatgaaaacatgaaagtcgcacagaaacgagatgctgtcctg
cagggaatgttctacttcaggaaagatatttgcaaagcaggtggcaacgctgtggtggac
ggctgtggcaaggcccagcaaggcgcggagctagccgcagaggagcacgaggagtacgcc
ctgatgagcatagacaccatcatcaatgggaaggaaggcgtgtttcctgggctgatccca
attctgaactcctacctggaaaacatggaagtggatgtggacaccagatgtagcattctg
aactacctgaagctgattaagaagagagcatctggagaactaatgacagtcgccaaatgg
atgagggagtttatcgcaaaccatcccgactataagcaagacagtgtaataaccgatcaa
ataaactatagccttattttaaagtgcaatcaaattgcaaatgaattatgtgaatgccca
gagttacttggaccagcatttaggagagtaagatatagtggaagtaaaatggactcttcc
aactag
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