Methylacidimicrobium sp. AP8: MTHMO_1099
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Entry
MTHMO_1099 CDS
T06915
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit 1
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
meap
Methylacidimicrobium sp. AP8
Pathway
meap00290
Valine, leucine and isoleucine biosynthesis
meap00660
C5-Branched dibasic acid metabolism
meap01100
Metabolic pathways
meap01110
Biosynthesis of secondary metabolites
meap01210
2-Oxocarboxylic acid metabolism
meap01230
Biosynthesis of amino acids
Module
meap_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
meap00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MTHMO_1099 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MTHMO_1099 (leuC)
Enzymes [BR:
meap01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MTHMO_1099 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
MTHMO_1099 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
CAB4243437
UniProt:
A0A7R8QG44
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Position
I:complement(1077051..1078424)
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AA seq
457 aa
AA seq
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MTLTEHLLARASGKKTVSPGDNIWVNVDVLLTHDICGPGTIGVFQREFGKSARVWDPRKI
VIIPDHYIFTSDSQSNRNVDLLREFAREQGLPYFYDVIDDERGRWQFDPSLGPLARQYGS
RYAGICHAAAPELGHARPGEIFLGTDSHTCTAGAFNLFSTGIGNTEAGFVLGTGKLLLKV
PPTLHFRLEGELPKGVMAKDVILEIIGRIGFDGATYCAMQFDGPGVAGLSMEDRMTIANM
AIEAGGKNGVFPADQTTTDFVRESCTRNGTRVDFEPVELDPKARFQAEYTIDLSTLRPTV
AQPPNPGNRELAERLSSVRIDRAYLGSCTGGKLSDFLAFAQILNGRTVAVETFAVPATPK
VVAELHRRRIDGKSVWEILRSAGVQLTENPSCAACLGGPMDTFGRLDRPLVCISATNRNF
PGRMGHKESKVYLASPYTVAASALTGRITDPREYLSS
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atgactctcaccgaacatcttcttgcgcgggcgagcggaaaaaaaaccgtctcccccggc
gataatatttgggtaaacgtggatgtccttttgacccacgacatctgcggccccgggacc
attggcgtctttcagcgggaattcggcaaatcggctcgagtctgggatccgcgcaaaatt
gtgattattcccgatcattacatcttcacctccgattcccagtcgaaccggaacgtcgat
ttgctccgcgaattcgcccgcgagcaggggctgccctacttctacgacgtgatcgacgac
gaaaggggccgctggcagttcgacccctccctggggcccctggcccgtcaatacggcagc
cgttacgcgggcatctgccatgccgccgcgcccgagctgggccatgcccggcccggagag
atctttctgggcaccgacagccacacctgcaccgccggagccttcaacctattctccacc
ggtatcggcaacaccgaagcaggatttgtactgggcacgggaaagttgctcctcaaggtg
ccgcccaccctgcacttccgcttggaaggggagcttcccaagggagtcatggcaaaggat
gtgatcctggagatcatcggtcgcattggattcgacggggcgacctactgcgctatgcag
ttcgacggccccggcgttgccggcctctccatggaggaccggatgacaatcgcgaacatg
gcgatcgaagcgggcggcaaaaacggggtcttccccgccgaccaaacaaccaccgacttc
gtgcgggaaagctgcacgcgcaacggaacccgtgtggacttcgagcccgtggagcttgat
ccgaaggctcgctttcaagccgagtacaccatcgatctttccacgctgcggccgaccgtg
gcccagccgcccaaccccggcaaccgagagctggcggaacgtctttcttcggtgcggatc
gatcgcgcctacctgggttcctgcaccggcggaaagctttccgacttcctcgccttcgcg
caaatcctcaacggaaggaccgtcgccgtagaaaccttcgccgtgcccgcgacgccgaag
gttgtcgcggagcttcaccggaggcggatcgacggaaagagcgtctgggagatcttacgt
tctgcgggcgtgcagctcacggaaaacccctcttgcgccgcctgcctgggaggccctatg
gacaccttcgggcggctcgaccggccgttggtctgcatttcggcgaccaaccggaacttt
cccgggcggatgggccacaaggaatcgaaggtctatctggcttctccatataccgtcgcc
gcctccgcgctgaccggacgcatcaccgatccgcgggaatatctgtcttcgtga
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