KEGG   Methylacidimicrobium sp. AP8: MTHMO_2070
Entry
MTHMO_2070        CDS       T06915                                 
Symbol
cimA
Name
(GenBank) (R)-citramalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
meap  Methylacidimicrobium sp. AP8
Pathway
meap00290  Valine, leucine and isoleucine biosynthesis
meap00620  Pyruvate metabolism
meap01100  Metabolic pathways
meap01110  Biosynthesis of secondary metabolites
meap01210  2-Oxocarboxylic acid metabolism
meap01230  Biosynthesis of amino acids
Module
meap_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:meap00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    MTHMO_2070 (cimA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    MTHMO_2070 (cimA)
Enzymes [BR:meap01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     MTHMO_2070 (cimA)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer HCS_D2
Other DBs
NCBI-ProteinID: CAB4244408
UniProt: A0A7R8QGU5
LinkDB
Position
I:complement(1994228..1995889)
AA seq 553 aa
MEAMIRAADADSRAEEAVSIYDTTLRDGAQGENVHFSLSDKLRITRKLDEVGISYIEGGW
PGSNPKDLAFFREVAHLPLRTSRIVAFGSTRRAGTAVEEDPQILMLLDADTQAVAVFGKT
WLLHVREILRATAAENLAMIQETVAFFKQRGKEVIYDAEHAFDGYREDPGYALETLAAAA
EAGADWVVLCDTNGGSLPKQVAELTALARQKIGCRIGIHTHNDGELAVANALAAVEAGAT
QVQGTINGYGERTGNCNLISTIANLELKLGKRALPAGSLSRLRELSYFVDETANLAPNPR
APFVGRCAFAHKGGTHVNAIGKLCRSYEHIEPEAVGNRRRILVGELSGRSNIVIKARELG
LTLREDDERTRGVLQQIKEMEGRGYEFEAADASFELLLRRRLLPYPPFFDLVEYHVSIRR
FPAKKYEVSEATVKLSVQGEPVYTVAEGDGPIHALDQALRGGLERFYPDLARVRLRDYKV
RILSPEGGAAAATRVLVESSDGVRSWTTVGVSTNIVEASWEALVDSIEYWMLRSERCAGA
GMPQARSEAASPP
NT seq 1662 nt   +upstreamnt  +downstreamnt
gtggaggcgatgataagagcggcggatgcggattcccgtgccgaggaggcggtctcgatc
tacgacaccacgctgcgggacggagcccagggggagaacgtccacttttccctttcggac
aagttgcgcatcacccggaagctcgatgaggtcgggatttcttacatcgagggagggtgg
ccgggcagcaatccgaaagatttagcctttttccgggaagtggcgcatctgccgcttcgg
acgagccggatcgtcgccttcggcagcacgaggcgggccggcaccgccgtggaggaggac
cctcagatcctcatgcttttggatgccgatacccaggctgtcgcggtcttcggcaagacc
tggcttctgcatgtccgcgagatcttgcgcgccaccgcggctgagaatttggcgatgatt
caggaaaccgtcgccttcttcaagcagcgcgggaaggaagtgatctatgatgccgagcac
gccttcgatggatatcgcgaggatcccggctacgccttggagaccttggcagccgctgcc
gaggccggagcggactgggtggttctctgcgacaccaacggcgggtcgctaccgaagcag
gtggcggagctcaccgcgctggctcggcagaagatcggttgtcgcatcgggatccatacg
cataacgacggcgagcttgcggtcgccaacgccctggccgcggtggaagcgggcgcgacc
caggttcagggcacgatcaacggctatggggaaaggacaggcaactgcaatctgatttcg
accatcgccaatctcgagctcaagctgggcaagcgtgctcttcccgccggcagtctttcc
cgcctccgggaactttcctacttcgtggacgagaccgccaacctcgctccgaacccgcgc
gcccccttcgtcggccggtgcgccttcgcccataagggcggcacgcatgtcaacgcgatc
ggcaagctctgccgcagctatgagcacatcgagccggaagccgtcgggaaccggcggcgg
atcctggtgggcgagctttccggtcggagcaatatcgtcatcaaggcgcgggagctgggg
ttgacgctccgggaggatgacgagcggacgcggggagtgttgcagcagatcaaggaaatg
gagggaaggggctacgaattcgaagcggccgacgcctcgtttgagctgcttctccgcagg
cgcctgctcccgtatccacccttctttgatttggtggaataccatgtttcgatccggcgc
ttccccgccaagaagtacgaagtttccgaggccacggtgaagctgtcggtccagggagag
cccgtctacaccgttgccgagggcgacggcccgattcacgccttggaccaggccctgcgg
ggagggctcgaacgtttttatccggatctggcccgcgtgcgcctgcgggactacaaggtg
cgcatattgagtccagaagggggtgctgcggcggcgacgcgcgtgctcgtcgagtcgtca
gacggggtgcgcagctggacgacggtgggtgtatccaccaacatcgtggaggcttcctgg
gaggctcttgtcgacagcatcgaatactggatgctccgttcggagcgatgcgcgggtgcg
ggcatgccgcaagctcgctcagaggcggcctcgcctccgtag

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