Metabacillus sp. B2-18: LPC09_24865
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Entry
LPC09_24865 CDS
T09916
Symbol
cobA
Name
(GenBank) uroporphyrinogen-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mebz
Metabacillus sp. B2-18
Pathway
mebz00860
Porphyrin metabolism
mebz01100
Metabolic pathways
mebz01110
Biosynthesis of secondary metabolites
mebz01120
Microbial metabolism in diverse environments
mebz01240
Biosynthesis of cofactors
Module
mebz_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mebz_M00924
Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
mebz_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mebz00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
LPC09_24865 (cobA)
Enzymes [BR:
mebz01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
LPC09_24865 (cobA)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
LPC09_24865 (cobA)
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Gene cluster
GFIT
Motif
Pfam:
TP_methylase
HEM4
Motif
Other DBs
NCBI-ProteinID:
UGB33465
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Position
complement(4979205..4980629)
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AA seq
474 aa
AA seq
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MSIGKVYLVGAGPGDQELITVKGMEAIKKADVILYDRLVNPRLLEYAPPTCELIYCGKLP
TRHFMRQHEINATLVEKALAGFTVVRLKGGDPSVFGRVGEEAQALAEQNVPYEIVPGITS
GIAAPLYAGIPVTHRDYAGSFAVVTAHDKSKEGKPNIDWEGLARGVQTIAFYMGISNLEH
ICENLVLHGKSPDTPVIIIRWGTWSRQQSVVGTLSTIVEKVREENIQNPAITLVGDIVET
RDKVKWFENQPLFGQQILYVRGSAGEESNAQHLRNQGADVIECPKWTVKENEVEIELLEK
LSSYKAILFLSSQAVTAFFNQLKRHRVDIRQISAELCCQNETALKELELMGLYPSLEMAD
QENLLIVGPEITAKRKLNLDLTYKKYDYLSIYQSYIDRRYDSIIKRSVEDADLTSIVFTS
GDAVETWINGEFHENMFSQEDEQSLEIICENDEALDAVLSHELPAKLNMELSLI
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgagcattggaaaggtgtatctagtcggagcgggtcctggagatcaggaattaatcact
gtaaaaggaatggaagcgatcaagaaggcagatgttattctttatgatcgacttgtaaat
ccaaggctgcttgaatatgcaccacctacctgtgaactaatctattgtgggaaactgcct
actcgtcattttatgagacaacacgaaatcaatgcaactttagtggaaaaagcattagct
ggctttactgttgttcgattaaaaggtggagacccgagtgtttttggcagagtaggtgag
gaggctcaagctttggcagagcaaaatgtgccatatgaaatcgttcccggcattacttct
ggtattgctgctcctctatatgctggtattccggtaacacatcgagattatgcaggatca
ttcgctgttgttactgcccatgataaatcaaaagaaggtaaaccaaatattgactgggaa
ggcttagcaagaggtgttcaaacaattgccttttatatgggtatttcaaacctggagcat
atttgcgaaaaccttgtgcttcacggtaaatcacctgatacaccagttatcattattagg
tggggaacatggagcagacagcaaagtgtagtaggcactctttctactattgttgaaaaa
gttagagaagaaaacattcaaaacccagccattacattagttggcgatattgtagaaaca
agagataaagttaaatggtttgaaaatcagcctttatttggtcaacaaattttatatgtt
cgaggaagtgccggagaagaaagtaatgctcagcacttaagaaatcagggtgcagatgta
attgaatgtcctaaatggacggtaaaggaaaacgaagtagagattgaattattggagaaa
ctatcctcatataaggcgatattatttttatcttcccaagcggttactgcctttttcaat
cagttgaaaaggcatagagttgatatccgccagatttcagcagaactttgttgtcaaaat
gaaacagctttaaaagagttagaattaatgggattataccctagcttggagatggctgat
caagaaaatcttctgattgttggccctgaaataactgctaagagaaagctgaatttagat
ttaacctataaaaaatatgactatctaagtatttatcaatcctatattgatcgaagatac
gattcaattataaaacgatctgttgaagatgctgaccttacatcgattgtgtttacttca
ggagatgcggttgaaacatggataaatggagaatttcatgaaaacatgttctctcaagaa
gatgaacaatccttagaaattatttgtgaaaatgatgaagcattagacgcagtcttgtct
catgaacttccagcaaaattaaatatggagttatctctaatctaa
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