Methylocystis echinoides: RVU70_11640
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Entry
RVU70_11640 CDS
T10963
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
meci Methylocystis echinoides
Pathway
meci00280
Valine, leucine and isoleucine degradation
meci00640
Propanoate metabolism
meci00785
Lipoic acid metabolism
meci01100
Metabolic pathways
meci01110
Biosynthesis of secondary metabolites
meci01210
2-Oxocarboxylic acid metabolism
Module
meci_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
meci00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
RVU70_11640 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
RVU70_11640 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
RVU70_11640 (pdhA)
Enzymes [BR:
meci01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
RVU70_11640 (pdhA)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
XCP54249
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Position
2383539..2384615
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AA seq
358 aa
AA seq
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MGLHTIIDSRIDLIRFLTPDGELCENTPLPVSDEALLHFYRAMTRTRAFDGKAIALQRTG
QLGTFASALGQEAVGVGVACAMEARDVLVPSYRDHAAQFLRGMSMAECLLYWGGDERGSD
FTNSRDDFPNCVPVATQVAHAVGAAYAFSLRKEERVAVTFIGDGGTSNGAFYEALNMAGV
WNAPVVMVINNNGWAISTPRALESAAATLAQKGVAAGVACQQVDGNDVVAVFEAARRAIA
KARAGDGPTLIEALTYRLGDHTTADDATRYRDPEVVQREWTREPIARLRAYLLCKGLWSK
EQEAELLKQCGAEVAEAVATYTSTPVASSDAMFDYLYEEPPQLLKDQREIARRFAPAK
NT seq
1077 nt
NT seq
+upstream
nt +downstream
nt
atgggattgcacaccatcatcgactcaaggattgatctgatccgctttctcaccccggac
ggcgagctttgcgagaacacgccattgccggtgagcgacgaggccttgctgcacttttac
cgcgccatgacccgcacgcgcgctttcgacggaaaagcgatcgcgctgcagcggacgggg
cagctcggaacctttgcctcggcgcttggccaggaagcagtcggcgtgggcgtggcgtgc
gccatggaggcgcgcgacgttctcgttccttcttatcgcgaccatgcggcgcagtttctg
cgaggcatgagcatggcggaatgcttgctctattggggcggcgacgagcgcggcagtgat
ttcacgaattcgagggacgactttccgaattgcgtcccggtcgccacgcaagtcgcccac
gctgtcggcgcggcctatgctttctcactgcgcaaagaggagcgcgtcgccgtgaccttc
attggcgacggcggcacctccaatggagcgttttacgaagcgctgaatatggcgggcgtc
tggaacgccccggtcgtcatggtcatcaacaacaacggctgggccatctcgacgccgcgt
gcgctcgaaagcgccgccgccactctggcgcaaaagggagtcgcggccggcgtcgcctgc
cagcaggtcgacggcaatgacgtcgtcgcggtttttgaagccgcccgacgggctattgca
aaggcgcgagcgggcgacgggccgacattgatcgaggcgctgacctatcgcctcggcgat
catacgacggccgacgacgcgacgcgctatcgcgatccggaagtcgtccagcgtgaatgg
acgcgtgagcccatcgcccgtctgcgcgcctatcttctttgcaagggcctctggtcgaag
gaacaggaggctgaactcctgaagcaatgcggggcggaagtcgccgaagccgtggcgacc
tatacctctacccccgtcgcctcgagcgacgccatgttcgattatctttatgaagaaccg
ccgcagttgcttaaagatcagcgcgaaatcgcgcggcgcttcgctcccgcaaaatag
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