Methylobacterium sp. CLZ: CLZ_21575
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Entry
CLZ_21575 CDS
T10449
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mecl Methylobacterium sp. CLZ
Pathway
mecl00290
Valine, leucine and isoleucine biosynthesis
mecl00660
C5-Branched dibasic acid metabolism
mecl01100
Metabolic pathways
mecl01110
Biosynthesis of secondary metabolites
mecl01210
2-Oxocarboxylic acid metabolism
mecl01230
Biosynthesis of amino acids
Module
mecl_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mecl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
CLZ_21575 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CLZ_21575 (leuC)
Enzymes [BR:
mecl01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
CLZ_21575 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
CLZ_21575 (leuC)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Aconitase
AcnX_3rd
Motif
Other DBs
NCBI-ProteinID:
QIJ76941
LinkDB
All DBs
Position
4685437..4686846
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AA seq
469 aa
AA seq
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MTAPRTLYDKIWDDHVVDVEPDGSALLYIDRHLVHEVTSPQAFEGLRVAGRKVRAPHKTL
AVVDHNVQTSDRSKGIEDPESRTQLEALAENVRDFGIEFYDALDRRQGIVHIIGPEQGFT
LPGQTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLIQRKAKNMRVTVDGILPPGV
SAKDIVLAIIGEIGTAGGTGHVIEYAGEAIRALSMEGRMTICNMSIEGGARAGMVAPDET
TYAYVKDRPKAPKGAAFDAARRYWESLVSDEGAHFDREIRLDAANLPPLVSWGTSPEDIV
SILGTVPDPAQIADENKRQSKEKALAYMGLTPGTRMTDVTLDRVFIGSCTNGRIEDLRIV
AKMVEGRKVHDGVSAMVVPGSGLVKAQAEAEGIDRILKDAGFDWREPGCSMCLGMNPDKL
RPGERCASTSNRNFEGRQGPRGRTHLVSPAMAAAAAVAGRFVDVREWRN
NT seq
1410 nt
NT seq
+upstream
nt +downstream
nt
atgaccgcgccgcgcaccctctacgacaagatctgggacgaccacgtcgtcgatgtcgag
ccggatggctccgccctcctctacatcgaccgccacctcgtgcacgaggtgacgagcccc
caggcgttcgaggggcttcgcgtggccggccgaaaggtgcgcgcgccgcacaagacgctg
gcggtggtcgatcacaacgtccagacctcggaccgctccaagggcatcgaggatccggag
agccgcacccagctggaggcgctcgccgagaacgtgcgcgatttcggcatcgagttctac
gacgccctcgatcggcgccaaggcatcgtccacatcatcgggccggagcagggcttcacg
ctgccgggccagacgatcgtctgcggtgattcccacacctcgacccacggcgccttcggc
gcgctggcccacggcatcggcacctcggaagtcgaacacgtgctcgccacgcagacgctg
atccagcgcaaggccaagaacatgcgcgtcaccgtcgacggcatcctgccgccgggcgtg
agcgcgaaggacatcgtgctcgccatcatcggcgagatcggcaccgccggcggcaccggc
cacgtcatcgagtatgccggcgaggcgatccgcgccctctcgatggagggccggatgacg
atctgcaacatgtcgatcgagggcggcgcgcgggccggcatggtcgcccccgacgagacc
acctacgcctacgtcaaggaccgcccgaaggcgccgaagggcgccgccttcgatgccgcc
cgccgctactgggagagcctcgtcagcgacgagggggcacatttcgaccgcgaaatccgt
ctcgacgcggcgaacctccccccgctggtctcctggggcacttcgccggaggacatcgtc
tcgatcctcggcacggtgcccgatccggcacagatcgccgacgagaacaaacggcagtcc
aaggagaaggcgctcgcctatatgggcctgacgccgggcacgcggatgaccgacgtcacg
ctcgaccgggtgttcatcggctcctgcaccaacggccggatcgaggatctgcggatcgtc
gccaagatggtcgagggccgcaaggtccatgacggcgtctcggcgatggtggtgccgggc
tccggcttggtgaaggcgcaggccgaggccgaggggatcgaccgcatcctgaaggatgcg
ggcttcgactggcgtgagcccggctgctcgatgtgcctgggcatgaacccggacaagctg
cgtcccggcgagcgttgcgcctcgacctcgaaccgcaacttcgagggccgccagggcccg
cgcggccgcacccacctcgtctccccggcgatggcggcggcggcagcggtggccggccgc
ttcgtcgacgtccgcgagtggcgcaactga
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