Methylosinus sp. C49: MSC49_08730
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Entry
MSC49_08730 CDS
T09855
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
mecq
Methylosinus sp. C49
Pathway
mecq00280
Valine, leucine and isoleucine degradation
mecq00640
Propanoate metabolism
mecq00785
Lipoic acid metabolism
mecq01100
Metabolic pathways
mecq01110
Biosynthesis of secondary metabolites
mecq01210
2-Oxocarboxylic acid metabolism
Module
mecq_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mecq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
MSC49_08730
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
MSC49_08730
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MSC49_08730
Enzymes [BR:
mecq01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
MSC49_08730
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
BBU60938
UniProt:
A0A679F3I2
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Position
complement(940046..941272)
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AA seq
408 aa
AA seq
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MRTWIMNWARARAIQALFGSRSKKFPRADEKREAAPYVSLTKLEAGPMTIGVSFQIDFLR
FLSASGELDPATPREAIDPELLLGLYHAMTRTRAYDGKAIALQRTGKLGTFASALGQEAI
GVGIGAAMRSEDVLAPSYRDHGAQLLRGMTMVENLVYWGGDERGSDYAVPRSDFPICVPV
GTQVAHAAGAAYAFKLRSEKRVAVTILGDGGASTGDFYSALNMAAVWRVPLVVIINNNQW
AISTPRDMESATATLAQKAVAAGVEGRQVDGNDVIAMRHVAHAAIEKARDGGGPTLIEAL
SYRLGDHTTADDASRYRDVDIVRREAEKEPIARLRKYLAAQGLWSEEQEKALAKDCAEEV
ERAVAAYLATPPQAFSAMFDHLFAQLPESMRDQYEEARRFAPKDGGHG
NT seq
1227 nt
NT seq
+upstream
nt +downstream
nt
atgcggacatggatcatgaactgggcgcgcgcgcgagcgattcaagcgctcttcggctca
cgcagcaaaaaattccctagggcggatgaaaagcgcgaggcggcgccttacgtctctctg
acgaagctcgaggcaggcccgatgaccattggcgtctccttccagatcgactttcttcgt
ttcctctccgcgtcgggcgagctcgatcccgcgacgccgcgcgaagcgatagaccccgag
cttctgctcggcctctatcacgcaatgacgcgcacgcgtgcttatgatggaaaagcgatc
gctctgcagcgcaccggcaagctcggcactttcgcctccgctctcgggcaggaggcgatc
ggcgtcggcataggcgcggccatgcgcagcgaggatgtgctcgcgccatcctatcgcgat
catggagcgcaattgctgcgcggcatgacgatggtggaaaatctcgtctattggggcggc
gacgagcgcggcagcgattacgccgttccgcgcagcgactttccgatttgcgttcccgtc
ggcacgcaggtcgcgcatgcggccggcgcggcttacgccttcaagctgcggagtgagaag
cgcgtcgcggtgacgatcctcggcgatggcggcgcttcgaccggggatttctattcggcc
ttgaacatggccgcggtctggcgcgttccgctcgtcgtcatcatcaataataatcaatgg
gcgatctcgacgccgcgcgacatggaatcggcgaccgcgacactcgcgcaaaaggccgtc
gccgccggcgtcgaaggacgtcaggtcgatggcaatgacgtgatcgccatgcgccatgtc
gcgcatgcggcgatagagaaagcgcgcgacggcggcgggccgacgctcatagaggcgctg
agctacaggctcggcgaccacacgaccgcggatgacgcctcgcgctatcgagacgtcgac
atcgtgcgacgcgaggcggagaaggagccgatcgcgcggctgcgcaaatatctcgcggcg
cagggattgtggagcgaggagcaggagaaggcgctcgcgaaggattgcgcggaagaggtg
gaacgcgccgtcgccgcctatctcgcgacgccgccgcaggcgttctcggcgatgttcgat
catctcttcgcgcagctgccggagtcgatgcgcgatcaatatgaggaggcgcggcgcttc
gcgccgaaggatggcggccatggctga
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