Megasphaera elsdenii: MELS_0569
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Entry
MELS_0569 CDS
T01633
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
med
Megasphaera elsdenii
Pathway
med00230
Purine metabolism
med01100
Metabolic pathways
med01110
Biosynthesis of secondary metabolites
Module
med_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
med00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
MELS_0569
Enzymes [BR:
med01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
MELS_0569
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
AIRS
DUF5645
Motif
Other DBs
NCBI-ProteinID:
CCC72791
UniProt:
G0VMW3
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All DBs
Position
658506..662249
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AA seq
1247 aa
AA seq
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MQSIRRLYVAKKGVFADEAKRLLTDLQENLLIKGLTDIHIFHRYDVSGLDDAAFEAAKNM
IFSEPPVDAVYDELPAGKDDTVLAVEYLPGQYDQRADSAMQCLQMLTMKNDSLVRTAQVL
VLSGNLSADDVAAIKHYCINPVEAREASLDPVSTLEMPWEKPADVPVIDGFDAMDDAALK
ELSAHMGLAMSFDDLKFVQAYFRDEEKRNPTVTEIRVIDTYWSDHCRHTTFMTELTDVSF
EDGTFTAPIQRAYESYKTTREKLNRKKPQTLMDMATIAVKELKAAGKLDNLDESEEINAC
TIIIPVDVDGVEEEWLLLFKNETHNHPTEIEPFGGAATCLGGCIRDPLSGRSYVYQAMRV
TGAGDPRQSVKDTLVGKLPQRKLTTGAAKGYSSYGNQIGLATGEVKEYYNPGFIAKRMEI
GAVLGAAPRNNVVREEPLPGDIIILLGGKTGRDGCGGATGSSKKHTVESLETCGAEVQKG
NALTERKIQRLFRRHEVTVLIKRCNDFGAGGVSVAIGELTDGLDINLDKVPKKYEGLDGT
ELAISESQERMAVVVAPEHVDEFMKYAAEENLEATIVAVATDTKRLVMHWRDQNVVNITR
AFLDTNGVTQHRKAVVVAPEDKDFFKAPEVKDVAKTWLDTMGTLNIASEQGLAERFDSTI
GARTVLMPFGGKYQKTPVEGMVAKIPVEHGNTTTASIFTHGYDPDLAIWSPFHGALYAVI
QSIAKLVALGGDRKKVYLTMQEFFQSLGTNEKAWGQPVSALLGAFTAQQVMEVAAIGGKD
SMSGTFENLTVPPTLVSFAIAPEHTENIISPEFKAADDAVLLFDLPRDGEEMPDFDTFKA
HCDFLHQAVLDGKVKAMHAVGQGGIAAAVAQMAFGNGIGFAVDKAFAAQELFNLRYGSIL
VETDAATAAAWAGRDHVSLVGKTTAAADVTVDGVTISLKDLQNAWEKPLSHVFPIKSESG
TGDAELPLFTTYGPRRSEAFGTPRVFIPVCPGTNCEYDSAAAFERAGATTDVMVLRNNTP
QDLAESIDEMAKRIAKAQIIMFPGGFSAGDEPEGSGKFIATLFRNPVLSEALETLLYQRD
GLALGICNGFQALIKLGLLPYGHVQPLKADSPTLTYNTIGRHLSRMVETKVVSVMSPWFS
GCKAGDVHTVAISHGEGRFVATPEQIRELAAKGQIATQYVDLSGKATYDSEYNPNQSVLA
VEGITSPDGRVLGKMAHTERFSAEDVFQNIAGNKLQPIFKSGVEYFK
NT seq
3744 nt
NT seq
+upstream
nt +downstream
nt
atgcagtctatccgacgtttgtatgttgccaagaaaggtgtttttgctgatgaagcaaaa
cgattgctcactgatttacaggaaaacctgttgattaaagggttgaccgatattcacatt
ttccatcgctatgacgtatccggtctcgatgatgcggcttttgaagcggctaaaaatatg
attttctctgaaccgcctgtcgatgccgtatacgatgaattaccggctggcaaggacgat
acggtcctggccgttgaatatctgcctggccagtatgatcagcgcgccgattcggctatg
cagtgcctgcagatgctgaccatgaagaacgacagcctcgtccgcacggcacaggtcctc
gtcctgtcgggcaacttatccgctgatgacgtcgctgcaatcaaacattattgcatcaac
cccgtcgaagcccgcgaagcttcgctggatcccgtttcgactctggaaatgccttgggaa
aaaccggctgacgttcccgtcatcgacggttttgacgccatggacgacgctgctctgaaa
gaattgtcggcgcacatgggcctggctatgagcttcgacgatttgaaattcgtccaggcc
tacttccgggatgaagaaaaacgaaatccgacggttacagaaatccgcgtcatcgatacg
tactggtcggaccactgccgtcacacgacgttcatgaccgaactcactgatgtttccttt
gaagatggcaccttcacggcgcctatccagcgcgcttatgaatcgtataagacgacccgg
gaaaaattgaaccgcaagaaaccgcagaccctcatggatatggcgaccattgccgtcaaa
gaactgaaagcggccggcaagctcgacaatctcgacgaatcggaagaaatcaacgcctgc
accatcatcatccctgtcgatgtcgatggcgtcgaagaagaatggctcctcctcttcaaa
aatgaaacccataaccacccgacggaaatcgaaccgttcggtggtgcggctacctgcctg
ggcggctgtatccgcgatcccttgagcggccgttcctatgtctatcaggctatgcgcgtc
accggtgccggcgacccgcgccagtcggtcaaagatacgctcgtcggcaaactgcctcag
cgcaaactgacgacaggcgctgccaagggctacagctcctatggcaaccagatcggcctg
gctacgggcgaagtcaaggaatattacaaccccggcttcatcgccaaacgtatggaaatc
ggcgctgtcctcggcgctgcaccgcgcaataatgtcgtccgtgaagaaccgcttcctggc
gatatcatcatcctcctcggcggcaagaccggccgcgacggctgcggcggtgctacgggt
tcgtccaagaagcacaccgtcgaatccctggaaacctgcggcgccgaagtccagaagggc
aatgccctgacggaacgcaagatccagcgcctcttccgccgccatgaagttacggtcctc
atcaaacgctgcaacgacttcggtgccggcggtgtctccgtcgctatcggtgaattgacg
gacggcctggacatcaatctcgacaaagtcccgaagaagtacgaaggcctggacggtacg
gaactggctatttccgaatcgcaggaacgtatggccgtcgtcgtcgctccggaacacgtc
gatgaatttatgaaatacgcagctgaagaaaacctggaagcgacgatcgtcgccgtcgct
accgatacgaaacgcctggtcatgcattggcgcgaccagaacgtcgtcaatattacccgc
gctttcctcgataccaacggcgtcacccagcatcgcaaagccgtcgtcgtcgctccggaa
gataaagatttcttcaaagcgccggaagtcaaagacgtcgccaagacctggctcgatacg
atgggtaccttgaatatcgcctcggaacagggcctggctgaacgcttcgacagcaccatc
ggtgcccgcacggtcctcatgccctttggcggcaagtaccagaagacacctgtcgaaggc
atggttgccaagattcccgtggaacacggcaacacgacgacagccagcatctttacgcac
ggctatgatccggacctggctatttggagccccttccacggtgccctctatgccgtcatc
cagtccattgccaaactcgttgccctcggcggcgaccgcaagaaagtctacctgaccatg
caggaatttttccagagcctgggcacgaatgaaaaagcctggggccagccggtcagcgcc
ctcctcggtgctttcacggcccagcaggtcatggaagtcgctgctatcggcgggaaagac
agcatgagcggtacctttgaaaacctcaccgttccgccgacgctcgtttctttcgccatt
gcaccggaacatacggaaaatatcatctcgccggaatttaaagctgccgatgacgcagtc
ctcctcttcgacctgcctcgtgacggcgaagaaatgccggacttcgataccttcaaagcc
cattgcgatttcctccatcaggctgtcctcgatggcaaagtcaaagcgatgcatgctgtc
ggtcagggcggtatcgcagcggctgtggctcagatggccttcggcaatggcatcggcttc
gctgtcgacaaggcctttgctgcacaggaactgttcaatctccgctatggttcgatcctc
gtcgaaaccgacgccgctacggctgctgcatgggctggacgggatcacgtctccctcgtc
ggcaagacgacggctgctgccgatgtgactgtcgacggcgtgacgatttccctgaaagac
ctccagaacgcttgggaaaaaccgctcagccacgtcttccccatcaagagcgaaagcggc
acaggcgatgccgaactgcccttattcacgacgtatggtccgcgccgcagcgaagctttc
ggtactccgcgggtcttcatccccgtctgcccgggtacgaactgcgaatacgattcggct
gctgcctttgaacgggccggcgctacgacggatgtcatggtactgcgcaacaacacgccg
caggatctggcagaatccatcgatgaaatggccaaacgcattgccaaggcacagatcatc
atgttccccggcggtttcagtgccggtgacgaaccggaaggctcgggcaagttcattgcc
accttgttccgcaaccccgtcctgtcggaagctctggaaacgctgctctatcagcgcgat
ggcctggctctcggcatctgcaacggcttccaggctctgattaaactgggcctcctgccg
tatggccatgtacagcctttgaaggctgacagcccgactttgacgtacaacaccattggc
cgccatctgtcgcgcatggtcgaaacgaaagtcgtctccgtcatgagcccgtggttcagc
ggctgcaaggccggtgacgtccataccgtggctatctcccacggcgaaggtcgtttcgtg
gctacgccggaacagatccgtgaattggctgccaaaggccagattgcgacacagtacgtc
gacctctctggcaaagctacctatgatagcgaatacaacccgaaccagtccgtcctggct
gtcgaaggcattaccagtcccgatgggcgcgtcctcggtaagatggcacacacagaacgc
ttcagcgctgaagacgtcttccagaacattgctggcaacaaactccagccgatcttcaaa
tcgggcgtcgaatattttaagtaa
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