Megasphaera elsdenii: MELS_1869
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Entry
MELS_1869 CDS
T01633
Name
(GenBank) possible uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
med
Megasphaera elsdenii
Pathway
med00860
Porphyrin metabolism
med01100
Metabolic pathways
med01110
Biosynthesis of secondary metabolites
med01120
Microbial metabolism in diverse environments
med01240
Biosynthesis of cofactors
Module
med_M00924
Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:
med00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MELS_1869
Enzymes [BR:
med01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MELS_1869
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MELS_1869
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
T_hemolysin
Motif
Other DBs
NCBI-ProteinID:
CCC74087
UniProt:
G0VS47
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Position
2054706..2056226
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AA seq
506 aa
AA seq
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MNGIVYLTGAGPGDYRLLTLRGREVLERADVVIYDYLADPRLLEFAPPTAEKIYVGKKAA
DHTLSQDKIIDLLIAKAKEGKIVVRLKGGDPFVFGRGGEESRALHDAGLPFEIIPGVTSA
IGAPAYAGIPVTDRTAASSFAVVTGHEDPTKGQSSIHWDKLATAVDTLVFLMGVHNLPSI
TQQLVAHGRPATTPAALVRWGTKADQETLVATVGDIAEKAAACHFKAPAVFIVGDVVALR
PSMQWFDTKPLFGLTIAVTRTHAQAPDLTHRLEELGARCLEVPTIRITPPTDGYQALDTA
IADLEHYDWVIFTSTNGVDAFFRRLQHHGRDSRALGRAKLAAIGSATAKALTAYGLQADV
VPGAYCAEDLAAALEPHLSGKERILIPRAKEARSVLPDTLRRWGAVVDVCQAYCTVEASE
NGAVLKDLLARQTIDVVTVTSSSAVRSFLSLSQAQASDLDDITFACIGPITARTCQEAGL
KKIVTAQTYTIAGLAECITDWRIKQS
NT seq
1521 nt
NT seq
+upstream
nt +downstream
nt
atgaacggtatcgtttatctcactggcgccggtcccggcgactaccgcctgctcaccctg
cggggccgggaggtcctggaacgggccgatgtcgtcatctacgactatctggccgatccg
cgccttctagaatttgctccgccaacagcggaaaaaatatatgtcggcaaaaaagcggcc
gaccacaccttgtcccaagacaaaatcatcgacctgctcattgccaaagccaaagaaggc
aagattgtcgtccgtctcaaaggcggcgaccccttcgtcttcggccgcggcggcgaagaa
agccgggcgctccacgacgcgggcctgccctttgaaatcatcccaggcgtcacgtcggcc
atcggcgccccggcctatgccggtatccccgtgaccgaccggacggcggcttcgtccttt
gccgtcgtcacaggtcacgaagacccgaccaaaggccagtcatcgattcactgggacaaa
ctggcaacggccgtcgatacgctggtcttcctcatgggcgtccacaacctgccatccatc
acccagcagctcgtcgcccacggccgtcctgcgacgacgccggcagccctggtccgctgg
ggcaccaaggccgaccaggaaacgctggtggctacggtcggagatatcgccgaaaaagcg
gcggcctgccatttcaaggcaccggccgtcttcatcgtcggcgacgtcgtcgccctgcgg
ccgtccatgcagtggttcgacacgaagcccctcttcggcctgaccatcgccgtcacccgg
acccacgcccaggcgccggacctgacacatcgcctggaagaactgggtgcccgctgcctg
gaagtgccgaccatccgcatcacgccgccgacagacggctaccaggcgctggatactgcc
atagcggacctggaacattacgactgggtcatcttcaccagcaccaacggcgtcgatgcc
tttttccgccgtctccagcatcacggccgcgacagccgtgccctgggccgggccaaactg
gccgctatcggcagtgccacggccaaggccctgacagcttacggcctccaggctgacgtc
gtccccggcgcctactgtgccgaagacctggccgccgccctggagccgcacctttccggc
aaagaacgcatcctcatccccagggccaaagaagcccggtcggtcctgcccgacacactg
cgccgctggggcgccgtcgtcgatgtctgccaggcctattgcaccgtcgaagccagcgaa
aacggcgccgtcctgaaagacctcctggcccgccagaccatcgacgtcgtgaccgtcacc
agctcgtcagccgtccgcagtttcctctccctgagccaggcccaggccagcgacctggat
gatatcaccttcgcctgcatcggccccatcacggcccgtacctgtcaggaagcgggcctg
aaaaaaatagtgacagcccagacctacaccattgccggcctggctgaatgtattacagat
tggagaatcaaacagtcatga
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