Methylophilus sp. DW102: MTDW_13310
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Entry
MTDW_13310 CDS
T10702
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
medz Methylophilus sp. DW102
Pathway
medz00290
Valine, leucine and isoleucine biosynthesis
medz00660
C5-Branched dibasic acid metabolism
medz01100
Metabolic pathways
medz01110
Biosynthesis of secondary metabolites
medz01210
2-Oxocarboxylic acid metabolism
medz01230
Biosynthesis of amino acids
Module
medz_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
Enzymes [BR:
medz01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MTDW_13310 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
MTDW_13310 (leuC)
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NCBI-ProteinID:
BEV08031
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Position
1474250..1475656
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AA seq
468 aa
AA seq
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MAGKTLYDKLWDSHVVREEADGTCLIYIDRHLVHEVTSPQAFEGLRLAGRKPWRNSSIVA
NPDHNTPTKDWDKGIEDPVSRLQVETLDNNIKEFGALVYFPFKNKDQGIIHVIGPENGTT
LPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLVAKKSKRMLVKVDGQLGKGV
TAKDVALAIIGKIGTAGGTGYAIEFGGEVIRGLSMEGRMTLCNMAIEAGARAGLVAPDEK
TSAYLEGRLHAPKGEHWAQAVAYWSTLKSDADAEFDTIVTLNGAEIAPQVTWGTSPEQVL
PIGSTVPDPAQEADATKRTSIENALKYMGLTANTPIEQIQLDKIFIGSCTNSRIEDLRAA
ASVAKGKKVASNIKLAMVVPGSGQVKRQAEAEGLDKIFIEAGFEWREPGCSMCLAMNSDR
LSPGERCASTSNRNFEGRQGPGGRTHLVSPEMAAAAAIAGHFVDVRSA
NT seq
1407 nt
NT seq
+upstream
nt +downstream
nt
atggcaggtaaaacgctgtacgacaaattatgggattcgcatgtggtgcgtgaagaagca
gacggcacctgtctgatttacattgaccgccatctggtgcatgaagtgaccagcccacag
gcttttgaaggcttgcgtttggccgggcgtaaaccatggcgtaattccagcattgtggct
aaccctgaccacaatacaccgaccaaagactgggacaaaggcattgaagatccagtgtcc
cgtttgcaggtggaaacgctggataacaacatcaaagagtttggtgccttggtgtatttt
ccttttaaaaacaaagaccaaggcattattcatgtgattgggcctgaaaatggcacgacc
ttgcctggtatgaccgtggtctgtggcgatagccatacctcaactcatggtgcctttggc
gcgttggcgcacggcatcggtacctcagaggttgagcatgtcttggctacacaaaccctg
gtcgcgaaaaaatccaagcgcatgctggtgaaggtcgatggccaattgggcaaaggcgtg
acggccaaagacgtggcgctggcgattatcggcaaaatcggtaccgctggcggtacgggg
tacgcgattgagtttggcggcgaagtgatccgtggcttgtccatggaaggccgcatgacg
ctgtgtaacatggcgattgaagccggcgctcgtgcgggcctggtggccccggatgagaaa
acatcagcttaccttgaaggccgtctgcatgcgcctaagggcgagcattgggcgcaagct
gtcgcttactggagcaccctcaaatccgatgctgatgccgagtttgataccatcgtgaca
ttgaacggtgcagagattgctccacaagtgacttgggggacctcgcctgagcaagtgctg
cccatcggctccactgtgccggatcctgcccaggaagccgatgcaaccaaacgcaccagt
attgaaaacgcgctcaaatatatgggcttgactgccaataccccgattgagcaaattcag
ctcgataaaatctttattggttcctgcaccaactcgcgtattgaggacttgcgtgccgct
gccagcgtcgccaaaggtaaaaaagtggccagcaatatcaagctggcgatggtggtgccg
ggctctggccaggtgaagcgccaggccgaagctgaaggcttggacaagatttttattgag
gctggttttgagtggcgtgagcctggctgctccatgtgtctggccatgaactcagaccgc
ttgagccctggtgagcgttgcgcttcaacctccaaccgtaactttgaaggccgtcagggt
ccaggtggacgtacgcatttggtcagccctgaaatggcggcagctgctgcgattgccggt
cattttgttgacgtgcgcagcgcataa
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