Methylophilus sp. DW102: MTDW_19860
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Entry
MTDW_19860 CDS
T10702
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
medz Methylophilus sp. DW102
Pathway
medz00230
Purine metabolism
medz01100
Metabolic pathways
medz01110
Biosynthesis of secondary metabolites
Module
medz_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
medz00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
MTDW_19860 (purL)
Enzymes [BR:
medz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
MTDW_19860 (purL)
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Ortholog
Paralog
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
BEV08686
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Position
2167760..2171671
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AA seq
1303 aa
AA seq
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MSSQAQFLSLRGSAALSQFRLDKLYRALKASAPNIAHIYTEFVHFAFSESALSVSEQDTL
RQILTYGPHTDIESPTGELLLVIPRIGTISPWASRATDIAHNCGLGHLLRLERGIAYYVT
TANGQALTEAEKQALRTAIQDRMTETVVYQLADAEKLYHHADPKPLSSVDILAGGKAALE
AANSEMGLALSPDEVDYLLENYRKMGRNPTDVELMMFAQANSEHCRHKIFNADWVIDGVQ
QELSLFNMIRNTHKLNPGNTVVAYSDNSSIVQGQKTKRFYPAADHSYQFVEDDMHYLMKV
ETHNHPTAISPFAGAATGAGGEIRDEGATGIGSKPKAGLTGFSVSNLNLPDFKQPWETNY
GKPGRIASPLQIMIDGPLGGAAYNNEFGRPNIAGYFRTFELETPAADGKREMRGYHKPIM
LAGGVGNISDSHSHKNSIPPGSALIQLGGPAMLIGLGGGAASSMDTGANTENLDFDSVQR
GNPELQRRAQEVIDRCWQMGDNNPILSIHDVGAGGISNAFPELVNDAKVGAVFQLRDVHN
EEPGMSPRELWSNEAQERYVLAVTQDQLPLFEAICERERCPFAVVGVTTEERHLTVEDRH
FDNKPVDMDLSVLLGKPPKMLRDVKSVNKTLPAFDTGNVVLHDAVSRVLRLPGVADKTFL
ITIGDRSVTGLIARDQMVGPWQVPVSNVAVTCAGFETNIGEAFAIGEKAPLALIDAPASG
RMAIGEAITNIAAAAISDIGNLKLSANWMAPAGHAGEDAALYATVKTVGMELCPALGISI
PVGKDSMSMKTVWQDQGENKAVTAPISLVISAFANTPDVRKTLTPQLRTDLGDSQLILID
LGNGKNRMGGSALAQVYQQLGNSVPDVDQPAQVKAFFAAIQQLNHEGKLLAYHDRSDGGL
FVTLAEMAFAGHCGLNLDLSALAGDNIALLFNEELGAVLQVRASDTATIVQQLQQQLGDC
VHAIGHVTAGQDIVIALKQARYQASRIDLHRMWSETTYRMQSLRDNPACAQQEYDRILNA
DDAGLHAQLTFDLNDNIAAPYINTGKRPNMAILREQGVNGQTEMAAAFDRAGFNSVDVHM
SDIISGRVALKDFAGLVACGGFSYGDVLGAGEGWAKSILFNARARDEFSAFFNRADTFAL
GVCNGCQMMSNLHSIIPGAAHWPHFVRNKSEQFEARVALVEILASPSIFFDGMAGSRMPI
AVAHGEGFTEFTDAGAVTSVLQQQLATVRYVDHAAQATEVYPFNPNGSPQGLTGFTTQDG
RFSIMMPHPERVFRAVQHSWRPDGWQEDGPWMRMFRNARKFVG
NT seq
3912 nt
NT seq
+upstream
nt +downstream
nt
atgtctagtcaagcgcaattccttagcctgcgcggcagcgccgccctctctcaattccgt
ctcgataaactgtatcgcgccctcaaagccagcgcaccgaatatcgcccatatttacacc
gaattcgtgcactttgcgtttagcgagtccgccttgagcgtgagcgagcaagacaccctg
cgccagattctgacttacggaccgcacacggatatcgagtccccgacaggcgagttgctg
ctggtgattccgaggataggcacgatttcgccctgggcctcacgcgcgacggatattgca
cacaactgtggcctgggtcatctgctgcgtctggagcgtggcattgcctattacgtgacc
actgcgaacggacaggcattgaccgaagctgagaagcaagccttgcgcactgccatccag
gaccgcatgacagaaacggtggtctaccagctggcggatgcagaaaaactctaccaccat
gccgaccctaaacctttatccagtgtggatattttagctggcggcaaagcggcgcttgaa
gctgccaatagcgagatgggtttagccttgtcgccagacgaggtggattacctgctggaa
aactaccgcaaaatgggccgcaacccgaccgatgtcgaactgatgatgttcgcccaagcg
aactccgagcattgccgccacaagattttcaatgcagactgggtgattgatggcgtacag
caagagctgtcgctgttcaacatgatccgcaacacacacaaactcaatcctggcaacacc
gtggttgcctactctgacaacagctcaattgtacaaggccagaaaaccaagcgtttttat
ccggcagccgatcacagctaccagtttgtcgaagacgacatgcattatctgatgaaggtg
gaaacgcataaccaccccactgccatttcaccctttgccggggctgcgactggggcaggc
ggtgaaatccgtgatgaaggcgccaccggcataggctctaagccgaaagcaggcttgacc
ggcttctcggtctccaacctgaacctgcctgactttaaacagccttgggaaaccaattac
ggcaaacctggccgtatcgccagcccgttgcaaatcatgatagacggtcctttaggcggg
gctgcttataacaacgaatttggccgccccaatattgccggttacttccgtacctttgaa
ctcgaaacgcctgccgccgatggcaagcgcgaaatgcgtggctatcacaagccgatcatg
ctggcgggtggggtcggcaatatctctgacagccacagtcataaaaacagcattcccccc
ggctcagccctgattcagctgggcggcccggccatgttgattggccttggcggcggcgcg
gcctccagtatggataccggcgccaacacggaaaacctggactttgactctgtacaacgc
ggcaacccggagttgcaacgccgtgcgcaagaggtgattgatcgttgctggcaaatgggc
gataacaacccgattttgagcatccacgacgtgggtgccggtggtatttccaacgccttc
cctgagctggtcaatgatgccaaagtcggcgccgtgttccagttgcgtgatgtacataat
gaagagcctggcatgagtccgcgcgaactgtggagcaacgaagcgcaagagcgctatgtt
ctcgccgtcacgcaagaccagttgcccttatttgaagcaatttgtgaacgcgaacgttgt
ccgtttgccgtcgtcggcgtcaccacggaagaacgtcatctgacggtggaagaccgtcat
tttgacaacaagccggtggatatggatctgtctgttctgctgggcaaacccccaaaaatg
ctgcgtgatgtcaaatccgtgaacaagacgctgccagcgtttgataccggcaacgtggta
ttgcatgatgccgtgtcgcgtgtactgcgcttaccgggtgtggcagataaaaccttcctg
attaccattggtgaccgtagcgtgaccggcctcatcgcccgcgatcaaatggtcggcccg
tggcaagtgcccgtcagcaacgtggcggtgacctgtgccgggtttgaaaccaatatcggc
gaagcatttgccatcggggaaaaggcgcccttggcgctgatcgacgcaccggcttccggc
cgcatggccattggtgaagccatcaccaacattgccgccgccgcaatcagtgacattggc
aacctcaagctgtccgctaactggatggcacctgccggtcatgccggtgaagatgccgcg
ctgtatgccaccgtgaaaaccgtgggcatggaattatgtccggcgctcggcatcagcatc
ccggtcggcaaagactccatgagtatgaaaacggtctggcaagatcaaggtgaaaacaaa
gcagtcacagcccccatctcactggtaatttctgcctttgccaacacgccagatgtgcgt
aaaaccctgacgccgcaactgcgcactgatctcggcgacagtcagctgatcctgatcgac
ctgggcaatggcaaaaaccgcatgggcggctcggctttggctcaagtctatcaacagtta
ggcaacagcgtgcccgatgtcgaccaaccggcacaagtgaaagcattttttgccgcgatc
cagcaactgaatcacgaaggcaaactactggcttatcatgaccgctcagatggtggcctg
tttgtcacactggcagaaatggcgtttgccggtcattgtggcctcaatcttgacctcagc
gccctggctggcgacaacattgccctgctgtttaacgaagaattgggggcggtactgcaa
gtgcgcgccagcgatacggcaaccatcgtccagcaattgcaacagcagttgggtgactgt
gtgcacgccatcggccacgtcactgccggccaggacattgtcatcgcgcttaaacaggca
cgctaccaggcatcacgcatcgacctgcaccgtatgtggtctgaaaccacttaccgcatg
cagagcctgcgtgataacccggcctgtgcccagcaggaatatgaccgcatcctgaatgcc
gacgatgccggtttgcatgcgcagctgacttttgacctcaacgacaatattgcggcacca
tatatcaacaccggcaaacgccccaacatggcgattttgcgtgagcaaggtgtcaacggg
cagaccgaaatggcggctgcgtttgaccgcgcaggttttaacagcgtcgatgtgcatatg
agcgacatcatcagcggccgtgtggcactcaaggatttcgcaggcttggtggcttgcggt
ggcttctcttatggggacgtacttggtgcaggcgaaggctgggccaagtccatcctgttc
aacgcgcgggcacgcgatgaatttagcgccttctttaaccgtgcagacacctttgcactg
ggcgtctgtaatggttgccagatgatgagtaacctgcacagcattattccaggcgccgcg
cactggccgcactttgtgcgcaacaagtccgaacagtttgaagcacgcgttgccctggtc
gagattctggcctcgccgtctatcttctttgacggcatggcaggcagccgcatgccgatt
gctgtggcacatggcgaagggtttacggaatttactgatgcgggcgcggtcacaagtgtg
ctacaacagcaactggcaaccgtgcgttatgtggaccatgctgcgcaagcgaccgaagtt
tacccgtttaacccgaatggttctcctcagggcttgaccgggtttactacgcaagatggt
cgtttcagcatcatgatgccacatcctgaacgtgtgtttagagcggtacagcattcctgg
cggccagatggctggcaggaagatggtccctggatgcgcatgttcagaaacgcacgtaag
tttgtaggttaa
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