Methylobacterium currus: DA075_03010
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Entry
DA075_03010 CDS
T05184
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mee
Methylobacterium currus
Pathway
mee00300
Lysine biosynthesis
mee00550
Peptidoglycan biosynthesis
mee01100
Metabolic pathways
mee01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mee00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
DA075_03010
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
DA075_03010
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
DA075_03010
Enzymes [BR:
mee01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
DA075_03010
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AWB20029
UniProt:
A0A2R4WEU7
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All DBs
Position
1:653763..655235
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AA seq
490 aa
AA seq
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MTEPLWTLIDAAAAMGGRVVADADAPQNLSGISIDTRTLKVGDLFFAIRGEARDGHDFVR
DALARGAGAAVVAEERAADLAEAGPLIAVPSRDEASDGDAVLAAMRGLAVASRARTAARV
LAVTGSVGKTGTKEALRHVLAAQGATHASVASYNNHWGVPLTLSRMPASSEFGVFEIGMN
HAGEIAPLTRLVRPEIAIVTTVEPVHIEHFRSLSGIADAKGEIFSGLEPGGVAIINRDNP
NFERLKAHALASRAGRVVSFGEHREADVRAERIVMRPDLSIVDVRAMGVTVTYQLGTPGR
HTALNSLAVIAAVQALGADLALAALSLAQLRPPAGRGARHLLQVGDGEALLVDESYNANP
ASVRAALSTLAGVESAGRRIAVLGDMMELGTEAPRLHRELAQAVEEHGIDLVFTAGPLMQ
ELFEALPTARRAGARASSAELVDPVVAALRPGDAVMVKGSNSTRMGRIVEALKARYGGAA
DQDLAVGRSG
NT seq
1473 nt
NT seq
+upstream
nt +downstream
nt
atgaccgagccactctggaccctgatcgacgccgccgccgccatgggcggccgcgtcgtc
gcggatgctgacgcgccgcaaaacctgtccggaatctcgatcgacacccgcaccctgaag
gtcggggacctgttcttcgccatccgcggcgaggcccgcgacggccacgacttcgtgcgc
gacgcgctcgcccgcggcgccggcgccgcggtggtggccgaggagcgggccgccgacctc
gccgaggccgggccgctgatcgccgtcccctcccgtgacgaggcaagcgacggggatgcc
gtgctcgccgccatgcgcggcctcgccgtggcgtcgcgggcgcggaccgcggcgcgggtc
ctcgccgtcaccggctcggtcggcaagaccggcaccaaggaggccctgcgccacgtgctc
gcggcgcaaggcgccacccatgcctcggtcgcctcctacaacaaccattggggcgtgccc
cttacgttaagccggatgccggcctcgagcgagttcggggtattcgagatcggcatgaac
catgccggcgagatcgctcccctgacccgcctggtgcggcccgagatcgcgatcgtcacc
acggtcgagccggtccatatcgagcatttccgctcgctgtcgggcatcgccgacgccaag
ggcgagatcttctccggcctggagcccggcggcgtcgcgatcatcaaccgcgacaacccg
aatttcgagcgcctgaaggcccatgcgctcgcctcccgcgccggccgggtggtgagcttc
ggcgagcaccgcgaggccgatgtccgcgccgagcgcatcgtgatgcggcccgacctgtcg
atcgtcgacgtgcgggcgatgggagtgaccgtcacctaccagctcggcacgccgggccgg
cacacggcgctgaactcgctcgccgtcatcgccgccgtgcaggcgctcggcgccgacttg
gcgctcgcggccctgtcgctggcgcagctgcgcccgccggccgggcgcggcgcccgccac
ctcctgcaggtcggcgacggcgaggcgcttctcgtcgacgagagctacaacgccaacccg
gcctcggtgcgggcggcgctcagcacgctcgccggggtcgagtccgccggccgccgcatc
gcggtcctcggcgacatgatggaactcgggaccgaggcgccccgcctgcaccgcgagctg
gcccaggcggtcgaggagcacggcatcgacctcgtcttcaccgccggcccgctgatgcag
gagctgttcgaggcgctgccgaccgcccgccgcgccggcgcccgcgccagctcggccgag
ctcgtcgatccggtggtcgcggccctgcggcccggcgacgccgtgatggtcaagggctcg
aacagcacccgcatgggccggatcgtcgaggcgctcaaggcccgctacggcggggctgcg
gaccaggacctcgccgtcggccggtccggctga
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