KEGG   Methylomonas sp. EFPC3: PL263_15135
Entry
PL263_15135       CDS       T10335                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
meec  Methylomonas sp. EFPC3
Pathway
meec00290  Valine, leucine and isoleucine biosynthesis
meec00620  Pyruvate metabolism
meec01100  Metabolic pathways
meec01110  Biosynthesis of secondary metabolites
meec01210  2-Oxocarboxylic acid metabolism
meec01230  Biosynthesis of amino acids
Module
meec_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:meec00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    PL263_15135 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    PL263_15135 (leuA)
Enzymes [BR:meec01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     PL263_15135 (leuA)
SSDB
Motif
Pfam: HMGL-like IPMS_D2 LeuA_dimer
Other DBs
NCBI-ProteinID: WFP49423
LinkDB
Position
3384130..3385794
AA seq 554 aa
MLANPSVKYRPFPPLALPDRRWPNRTIAHAPIWMSTDLRDGNQALFEPMNAARKLRLFET
LCGIGFKQIEVAFPSASQTDFDFVRQLIAEQRVPDDVTIEVLSHARAPLLRRTVESLHGA
RSAIVHIVNATSQPFRELVLGMSKAQVLAMAVDAVCLVKELTAALPATDWQLQYSLETFT
ATELDYALEVADAVVEAWGATPDNKLILNLPSSVEHATPNVYADQIEWMHRRIARRDSVV
LSVHPHNDRGTAVAAAELALMAGAERVEGCLFGNGERTGNVDLVTLALNLYTQGIAPGLD
FSDIDAVARSFEACTGLSVPPRQPYAGDLVFTAFSGSHQDAIKKGFAAQKTGGLWNVPYL
PFDPADVGRGYDAVIRVNSQSGKGGIAHLLESHYGMVLPRRLQVEFAQVVQQQADAGGGE
IGHAQIWRLFNATYLADAGPLRYLGHRLAEIDGGQRIELELQWHGATRCVAGDGNGPLDA
AVAALAVLDYAVTIRNYEERSLGPSRHGGDARACAFVELAGPDGQPPRYGVGIDDNLLTA
SIKALISGVNRSAE
NT seq 1665 nt   +upstreamnt  +downstreamnt
atgttagccaacccttccgtgaaataccggccgtttccgccgctggcgttgccggaccgg
cggtggccgaaccgaaccatagctcacgccccgatctggatgagtaccgatctgcgtgac
ggcaaccaggccttgttcgagccgatgaacgcggcacgtaaactccgcttgttcgaaacc
ttgtgcggcatcggcttcaagcaaatcgaagtggcgtttccgtccgcctcgcaaaccgat
ttcgacttcgtccgccaattgattgccgaacagcgggttcccgacgacgtgacgatagaa
gtgctgagccatgcccgcgcgccgttgttgcgccgcacggtcgaaagcttgcacggcgcc
cgcagcgccatcgtccatatcgtcaacgccacctcgcaaccgttccgcgagttggtgctg
ggcatgagcaaagctcaagtcttggcgatggcggtcgacgcggtgtgtttggtcaaggaa
ttgaccgccgcgctacccgctaccgactggcagttgcaatacagcctggaaaccttcacc
gccaccgaacttgattacgcgctggaggtagccgacgccgtcgtcgaagcctggggtgcg
acgccggacaacaagctcattttgaatctgccgtcgtcggtggaacacgcgacgccgaac
gtctacgccgatcagatcgaatggatgcatcgccgcatcgcccgccgcgacagcgtggtg
ttgagcgtgcatccgcacaacgaccgcggcactgcggtggcagccgccgaactggcgttg
atggccggcgccgagcgggtcgaaggttgcttgttcggcaacggcgaacgcaccggcaac
gtcgatctggtcacgttggccttgaatttgtacacccagggcatcgcgccgggtctggat
ttttccgacatcgacgcggtcgcgcgcagtttcgaggcttgcaccggcttgagcgtaccg
ccgcgccagccttatgccggcgatttggtgttcaccgcattctccggctcgcaccaggat
gcgatcaagaaaggctttgccgcccagaagactggcggcttgtggaatgtgccctatctg
ccgttcgatccggccgacgtcggccgcggttacgatgcggtgatccgggtcaacagccaa
tccggcaagggcggcattgcccatttgctggaaagccattatggcatggtcttgccgcgc
cgcttgcaggtcgaattcgctcaagtggtgcagcaacaggccgacgccggcggcggcgag
atcggccatgcgcaaatctggcgcttgttcaacgcgacttatttggcggatgctgggccg
ctccgttacctcggccaccgtttagccgaaatcgatggcggccaacggatcgaattggaa
ctgcaatggcacggcgcaacgcgctgtgtggccggcgacggcaacggtccgctggatgcg
gcggtcgccgcgttggcggtgttggattacgctgtgaccatccgcaattacgaagaacgc
tcgctcggtcccagccgccacggcggcgatgcccgcgcctgcgccttcgtcgaactggcc
gggccggatggccagccgccgcgttacggcgtcggcatcgacgataatttgctgacggcg
tcgatcaaggcgctgatcagcggcgtcaatcgctcggccgaatag

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