Methylococcus sp. EFPC2: JWZ97_06450
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Entry
JWZ97_06450 CDS
T10116
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
meef Methylococcus sp. EFPC2
Pathway
meef00290
Valine, leucine and isoleucine biosynthesis
meef00660
C5-Branched dibasic acid metabolism
meef01100
Metabolic pathways
meef01110
Biosynthesis of secondary metabolites
meef01210
2-Oxocarboxylic acid metabolism
meef01230
Biosynthesis of amino acids
Module
meef_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
meef00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
JWZ97_06450 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
JWZ97_06450 (leuC)
Enzymes [BR:
meef01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
JWZ97_06450 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
JWZ97_06450 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
QSA98444
UniProt:
A0A974ZQG7
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Position
complement(1558769..1560325)
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AA seq
518 aa
AA seq
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MTGKTLYDKLWDAHLVCTEADGSALIYIDRQLVHEVTSPQAFEGLRLADRKPWRVGANLA
VADHNVPTAGREQGIADPVSRLQVETLDRNCAEFGITEFSMSDPRQGIVHVVGPEQGATL
PGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQCLVQRKAKNLLVKVEGQVGPGVT
AKDIVLAIIGRIGTAGGTGYTIEFAGSAIRALSVEGRMTVCNMAIEAGARAGLIAVDEAT
IDYVRGRPYAPQGELFERAAAAWRELHSDADAEFDAVVEIDAAALKPQVTWGTSPELVLP
VDASVPDPAREADPIKRESMERALNYMGLEAGTPLTAIPVDKVFIGSCTNGRIEDLRAAA
EVARGRKKADSVKQVLIVPGSGLVKQQAEAEGLDRIFTEAGFEWRDPGCSMCLAMNADRL
DPGERCASTSNRNFEGRQGYGGRTHLVSPAMAAAAAIYGHFVDVSTIASLPQAGAQEASA
QTTGASASVGAEEAAKPKRKPRSSGPGRAKTAKQGKEQ
NT seq
1557 nt
NT seq
+upstream
nt +downstream
nt
atgaccggaaaaaccctctacgacaagctttgggacgcgcatctcgtttgcaccgaggcg
gatggttccgcgttgatctatatcgatcgccaactggtgcacgaggtgacttcgcctcag
gccttcgaaggcctgcgtttggccgatcgcaaaccttggcgcgtcggcgccaatttggct
gtggccgaccataacgtgccgacggcggggcgcgagcagggcatcgccgatcccgtttcg
cgcctgcaagtggaaaccctggatcgcaactgcgccgaattcggtatcaccgagttttcc
atgtcggatccgcgccagggcatcgtgcatgtggtgggaccggagcaaggcgccacgctg
cccggcatgaccatcgtctgcggtgattcgcacaccgcgacgcacggtgcattcggcgcc
ctggccttcggcatcggcacctccgaagtcgagcatgtgctggcgacccaatgtttagtc
cagcgtaaggcgaagaacctgctggttaaggtcgaggggcaggtcggccccggcgtcacc
gccaaggacatcgtactcgccatcatcgggcgcataggcaccgcgggtggcaccggctac
accatcgagttcgccggttccgccatccgcgccctgtccgtggaaggccgcatgacggtc
tgcaacatggccatcgaggccggcgcgcgcgcgggcctgatcgcggtggacgaggccacc
atcgattatgtgcgtggacgtccctacgctccgcaaggcgagctgttcgaacgggccgcg
gccgcctggcgcgaactgcacagcgacgccgatgccgaattcgatgccgtcgtcgaaatc
gatgccgccgccctcaagccgcaagtgacctggggaacctcgcccgaactggtgttgccg
gtcgatgcgtccgtgcccgatcccgcgcgggaagccgatccgatcaagcgcgagagcatg
gagcgcgccctgaactatatggggctggaggccggcacgccgctcacggctattccggtc
gataaggtattcatcggttcctgcaccaacggccgtatcgaggacctgcgggcggcggcc
gaggtggccaggggacgtaaaaaggccgacagcgtcaaacaggtcctgatcgtccccggt
tccggcttggtcaagcagcaggccgaggccgaaggcctggatcggatatttaccgaggcg
ggcttcgaatggcgcgatccgggctgttccatgtgcctggccatgaatgccgacaggctg
gatccgggcgaacgttgcgcctcgacctccaatcgtaacttcgagggacgccagggctac
ggcggccgcacccatctggtcagtcccgccatggccgcggccgccgcgatttatggtcat
ttcgtcgatgtgagcacgatcgccagcctgccgcaagccggtgctcaggaagccagcgcc
cagaccactggtgcatcggcctccgtcggagccgaagaagctgccaaaccgaagcgcaag
cctcgctcgtccgggccggggcgcgccaaaaccgccaagcaaggtaaagagcaatga
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